transforming drug development - health 2.0 new orleans
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Transforming Drug DevelopmentIts not just for researchers you can participate!
Health 2.0 New Orleans
November 21, 2013
Thomas Krohn, RPh, MBA
Eli Lilly and Company
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Drug Development - today
Precompetitive Competitivepatent
Innovation Process
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Business Model Performance
Source: FDA.gov
Productivity Down, Costs Up Future revenues under pressure
Unsustainable Business Model
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Moores vs. Erooms Law
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The Far Side
by Gary Larson
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Incremental Improvement
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Disruptive Innovation
to S1'
to S2
S1
Time
Performance
Disruptive
Change
Simpler, Faster, Cheaper?
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Disruption in motion
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Generation and Access to Data
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Patient Digital Monitoring
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Patient Communities
Patients as microexperts not subjects
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Patient-Driven Research
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The Disruption
Power to the Patient
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Clinical Research as part of Healthcare
Public Perception 94% of people recognize the importance of participating in clinical research
in order to assist in the advancement of medical science. Yet 75% of the
general public state they have little to no knowledge about the clinicalresearch enterprise and the participation process. (www.centerwatch.com)
Less than five percent of cancer patients participate in clinical trials. If tenpercent participated, studies could be completed in one year, instead of thethree-five years that studies currently require. (National Cancer Institute)
It's not uncommon for your cancer doctor or treatment team to discuss theoption of a clinical trial as the best treatment choice for your cancer type.(www.mayoclinic.com)
Standard of Care Clinical Trial
Info & Innovation
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ClinicalTrials.Gov and Patients
98,000,000Pageviews/Month1
Sources:1) clinicaltrials.gov site2) D. Zarin 2007 Overview
47,000,000Patient driven pageviews/Month
2
What if.?
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1
Patient-Centric
Design
PatientVoice
2
Patient-Centric Study Representation & Voice
Study Representation
Informed ConsentDocumentCt.Gov
Study Design
Open
Platform
Patients
Clear eligibilityRisk/BenefitMy doctors roleStudy treatmentTime to resultsLogistics
Design Challenge
ctdesign.challengepost.com
November 14
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Clinical Open Innovation
Open
Platform
Patients
api.lillycoi.com
DailyUpdates
OpenWeb
RESTAPI
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Enabling patient matching to studies
Open
Platform
Patients
api.lillycoi.com
DailyUpdates
OpenWeb
RESTAPI
Patient StudyTarget Profiles
Study Sponsors
Patient &
Communities
Personal ElectronicMedical Records
MatchProcess
Consentto
Match
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Patient Engagement App Challenge
http://patientengagement.challengepost.com
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Join the transformation
Learn the business model Understand patient needs Identify options for value creation
Explore open data and patient engagement
Participate in challenges
Most people are afraid of making mistakes.Leaders are afraid of missing opportunities.
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References
Website: www.lillycoi.com API: api.lillycoi.com App Lab: labs.lillycoi.com
Whitepaper: link
Twitter: @Lilly_COI, @takmad
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Thanks!