transport across plasma membranes - weebly€¦ · transport across plasma membranes -simple...
TRANSCRIPT
![Page 1: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/1.jpg)
Transport across Plasma
Membranes
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-Simple diffusion: transport through lipid
bilayer, transport through channels, Ficks law of
diffusion.
-Facilitated diffusion: by carriers
Differences in diffusion Kinetics between the
previous modalities
Equivalent Concentration of particles.
Transport through plasma
membranes
Passive transport modalities
![Page 3: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/3.jpg)
-Osmosis: concept of osmotic pressure (Van’t
Hoff’s law), Oncotic (Colloid-osmotic) pressure.
Osmolarity, Osmolality
Hydrostatic pressure and filtration
Transport through plasma
membranes
Passive transport modalities
![Page 4: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/4.jpg)
- Primary active transport (ATP-ase carriers
or Pumps) (functions of pumps: Na+/K+ pump,
Ca++ pump, H+ pump, H+/K+ pump).
- Secondary active transport (Na+
dependent carriers) examples
Transport through plasma
membranes
Active transport modalities
![Page 5: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/5.jpg)
- Vesicular transport: endocytosis,
phagocytosis, transcytosis, pinocytosis and
exocytosis and its control in secretory cells.-
Transport through plasma
membranes
Active transport modalities
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Active Transport Mechanisms
• Primary active transport
• Secondary active transport
• Vesicular transport
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Types of Pumps
• Na+/K+ pump
• H+ pump
• H+/K+ pump
• Ca++ pump
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Phosphorylation &
dephosphorylation
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Types of Pumps
• Na+/K+ pump
• H+ pump
• H+/K+ pump
• Ca++ pump
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The importance of pumps for
cell functions
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Secondary Active Transport
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Secondary Active Transport
-Co-transport
-Counter transport
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Vesicular Transport
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Formation of vesicles at
ER
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Endocytosis
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Phagocytosis
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Receptor mediated
endocytosis
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Exocytosis
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Transcytosis
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Control of Transport
and activity of Enzymes
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Receptors & Enzymes
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Receptors & Channels
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Receptors & G proteins
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Control of Exocytosis
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Summary of Lectures
-Homeostasis
-Control of body functions by feed-back
mechanisms to keep homeostasis
-Functions of Cell organells (ER, Golgi
complex, Mitochondria, Lisosomes)
-Cytoskeletal structures and Functions:
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- Membrane structure and function of
lipids of plasma membrane including
phospholipids, cholesterol and PIP2)
-Functions of Protein structures of plasma
membranes (Channels, Carriers, Receptors,
Pumps, enzymes, cell markers, G proteins,
adhesion molecules)
-Activation of chemical gated channels
Plasma membrane
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-Simple diffusion: transport through lipid
bilayer, transport through channels, Ficks law of
diffusion.
-Facilitated diffusion: by carriers
Differences in diffusion Kinetics between the
previous modalities
Equivalent Concentration of particles.
Transport through plasma
membranes
Passive transport modalities
![Page 40: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/40.jpg)
-Osmosis: concept of osmotic pressure (Van’t
Hoff’s law), Oncotic (Colloid-osmotic)
pressure.Osmolarity, osmolality
Hydrostatic pressure
Transport through plasma
membranes
Passive transport modalities
![Page 41: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/41.jpg)
- Primary active transport (ATP-ase carriers
or Pumps) (functions of pumps: Na+/K+ pump,
Ca++ pump, H+ pump, H+/K+ pump).
- Secondary active transport (Na+
dependent carriers) examples
Transport through plasma
membranes
Active transport modalities
![Page 42: Transport across Plasma Membranes - Weebly€¦ · Transport across Plasma Membranes -Simple diffusion: transport through lipid bilayer, transport through channels, Ficks law of diffusion](https://reader033.vdocument.in/reader033/viewer/2022042712/5f8dddf8f59e0b6fce6f1399/html5/thumbnails/42.jpg)
- Vesicular transport: endocytosis,
phagocytosis, transcytosis, pinocytosis and
exocytosis and its control in secretory cells.-
Transport through plasma
membranes
Active transport modalities