trifecta of the trigeminal

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Trigeminal Trifecta Deborah Heath, DO Professor & Co-Chair OMM Mindy Hansen, MS, OMS IV ATSU SOMA

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Page 1: Trifecta of the Trigeminal

Trigeminal Trifecta

Deborah Heath, DO Professor & Co-Chair OMM

Mindy Hansen, MS, OMS IV

ATSU SOMA

Page 2: Trifecta of the Trigeminal

A.T. Still

“I want men and women to study

Osteopathy who reason and think for

themselves. It is never a question as to

what the remedy or the treatment will do to

the body, but what the body will do with

the remedy or treatment.”

Page 3: Trifecta of the Trigeminal

Introduction

Part I:

• Trigeminal/Occipital anatomy and physiology

• Neuromodulation – summary of evidence

based studies

Part II:

• Lab – integration of palpation, evidence and

observation

• Summary and conclusion

Page 4: Trifecta of the Trigeminal

Trigeminal Nerve “The 3 Twins”

V1 = ophthalmic

Sensory for: scalp&forehead; frontal&ethmoidal sinus; upper eyelid &conjuntiva; cornea; dura/meninges

V2 = maxillary

Sensory for: lower eyelid & conjunctiva; maxillary sinus; nasal cavity; upper lip; upper molar, incisor, & canine; superior palate; dura/meninges

V3 = mandibular

Sensory for: mucous membranes; external ear; lower lip; anterior 2/3tongue pain/temp (not taste); lower molars, incisor & caninesl dura/meninges

Motor for: medial and lateral pterygoids, masseter, temporalis;digastric anterior belly; tensor veli palatini &tympani

Page 5: Trifecta of the Trigeminal
Page 6: Trifecta of the Trigeminal
Page 7: Trifecta of the Trigeminal

Anterior/Middle

fossa:

Trigeminal nerve

Posterior fossa:

Upper 3 cervical

branches

Sympathetic

branches

Vagus

Hypoglossal

Page 8: Trifecta of the Trigeminal

Trigeminocervical Complex

Page 9: Trifecta of the Trigeminal

Trigeminal Nucleus

Main sensory nucleus:

posterior pons (touch &

pressure)

Spinal nucleus: extends to

the 2nd – 3rd cervical seg.

(pain & temp)

Mesencephalic nucleus:

around cerebral aqueduct

Motor nucleus: pons

(muscles of mastication,

tensor tympani, tensor veli

palatini, mylohyoid, ant

bellydigastric)

Page 10: Trifecta of the Trigeminal

Occipital

nerve

• Originates from

C2, C3

• Pierces fascia,

trapezius and

ascends the scalp

• Innervates scalp at

the top of the head,

the top of the ear

and over the

parotid glands.

Page 11: Trifecta of the Trigeminal

TRIGEMINAL REFLEXES

Page 12: Trifecta of the Trigeminal

Trigeminal Reflexes

Trigeminovascular system

Trigeminocardiac reflex

Trigeminocervical reflex

Trigeminomandibular reflex

Nociceptive Blink Reflex

Trigeminocervical complex C1-C3

“Hit your nose + eyes water” Reflex

“Sneeze in the sun” Reflex

Page 13: Trifecta of the Trigeminal

Occipital reflexes

• Influence on nociceptive blink reflex of trigem

Page 14: Trifecta of the Trigeminal

NEUROMODULATION

Page 15: Trifecta of the Trigeminal

How to affect change?

Pharmacology

Neuromodulation: peripheral (nerve blocks,

implantables or noninvasive)

Jurgens, T., Leone, M. Pearls and pitfalls: Neurostimulation in headache. Cephalgia. 33(8):512-525, 2013

Page 16: Trifecta of the Trigeminal

Neuromodulation

MOA

• Initially thought to be based on Gates Theory

• Evidence is suggesting PNS alters pain perception in central mechanisms

• There is a modulation of nerve activity within CNS pain processing and integration centers in the brain

Low freq = incite HA

High freq = inhibit HA

Page 17: Trifecta of the Trigeminal

Noninvasive Brain Stim

Transcranial magnetic stimulation (TCs)

• Uses weak magnetic field to alter the global currents

in the brain

• Repetitive pulses used for neuromodulation (rTMS)

• High frequency = excites cortex

• Low frequency = depresses cortex

Transcranial current stimulation (tCS)

• Direct or alternating current delivered to scalp via

electrodes

Page 18: Trifecta of the Trigeminal

Mechanical Stimulation

Mechanical pressure on trigeminal nerve endings can

elicit pain reduction and motor relaxation

• Uses mechantransduction mechanisms – mechanical

stimulation is translated into electrical, chemical, and

mechanical signals

Page 19: Trifecta of the Trigeminal

Q’s on Anatomy/Physiology?

Let’s put it all together

Page 20: Trifecta of the Trigeminal

Lab

Page 21: Trifecta of the Trigeminal

A.T. Still – to a student

“I could not wish you any better luck

than when you start practicing you may

come up against hard problems that

you have to solve. Go to a small

town...but sleep with your anatomy

under your pillow, and don’t forget you

are supposed to have a brain inside

your skull.”

Page 22: Trifecta of the Trigeminal

FIRST and FOREMOST– No Agenda

1. History – any recent: HA, head injury, sacral

injury, dental work, eye strain?

2. General Scan: assess head, OA, cervical,

thoracic, lumbar, sacrum

3. MONITORING!!

Page 23: Trifecta of the Trigeminal

Sub-occipital

Triangle

“The HA

Triangle”

Pay attention to

what attaches

where!

Page 24: Trifecta of the Trigeminal

Let’s get started

OA Junction – what do you assess?

• Tenderness when comparing sides

Any changes with an OAD?

What doesn’t change might be related to the trigeminal and occipital influences – or a restriction downstream.

Page 25: Trifecta of the Trigeminal

How do you monitor?

This is a major key in knowing when tissues

change!

It’s different and more comprehensive than just

checking for motion.

Being able to know that the area of restriction is

changing is invaluable!

Page 26: Trifecta of the Trigeminal

Occipital Nerves

Don’t forget – these innervate the posterior fossa

of the head

Page 27: Trifecta of the Trigeminal

Trigeminal and Occipital

interaction

Find the Occipital notches

• Greater is 1 cm lateral to inion

• Lesser is halfway b/t inion and mastoid

Any tenderness? Any response where you are

monitoring?

Now check V1, V2, V3 for tenderness and

reciprocal change in the OAD where you’re

monitoring

Page 28: Trifecta of the Trigeminal

Trigeminal Foramen

Page 29: Trifecta of the Trigeminal

Auriculotemporal

Page 30: Trifecta of the Trigeminal

Trigeminal

V1, V2, V3 – if you find tenderness and

reciprocal changes at the OA

• Find a pulse frequency and pressure that

allows the changes of TART at the OA

where you are monitoring

Page 31: Trifecta of the Trigeminal

Trigeminal

Next in the progression is checking C2

(this is where the TCC lives, remember?)

• The association may be ipsilateral or

contralateral – you have to pay attention to

the monitoring hand

Page 32: Trifecta of the Trigeminal
Page 33: Trifecta of the Trigeminal

Trigeminal

RECHECK

Do you have any autonomic changes like heat and moisture?

Recheck the spine, has anything changed?

See if the inhibitory signals have influenced the rest of the system.

Page 34: Trifecta of the Trigeminal

No one technique is everything

• Like any art, no one technique or tool will be

the answer for every patient.

• If something doesn’t change – it means

something else is holding it.

• Ask the question: “What does this person need

at this moment.”

• This tool can be extremely effective in the

right context.

Page 35: Trifecta of the Trigeminal

Thank you from ATSU SOMA

Deborah Heath, DO

Mindy Hansen MS, OMS IV

Page 36: Trifecta of the Trigeminal

References1. Cook, I.A., Espinoza, R., Leuchter, A.F. Neuromodulation for Depression. Neurosurg Clin N Am. 25:103-116,

2014.

2. Hong, J., Ball, P.A., Fanciullo, G.J. Neurostimulation for Neck Pain and Headache. Headache. 54:430-444, 2014.

3. Russo, A., Tessitore, A., Tedeschi, G. Migraine and Trigeminal System- I can Feel it Coming…Curr Pain Headache Rep. 17:367, 2013.

4. Jurgens, T., Leone, M. Pearls and pitfalls: Neurostimulation in headache. Cephalgia. 33(8):512-525, 2013.

5. Lambru, G., Matharu, M. Peripheral neurostimulation in primary headaches. Neurol Sci. 35(Suppl 1):S77-S81, 2014.

6. Deer, T. et al. The Appropriate Use of Neurostimulation: Stimulation of the Intracranial and Extracranial Space and Head for Chronic Pain. Neuromodulation. 17:551-570, 2014.

7. Watson, D., Drummond, P. Head Pain Referral During Examination of the Neck inMigraine and Tension-Type Headache. Headache. 52:1226-1235, 2012.

8. Watson, D., Drummond, P. Cervical Referal of Head Pain in Migraineurs: Effects on the Nociceptive Blink Reflex. Headache. 54:1035-1045, 2014.

9. Tavanaiepour, D., Levy, R. Peripheral Neuromodulatoin for Treatment of Chronic Migraine Headache. Neurosurg Clin N Am. 25:11-14, 2014.

10. Schabrun, S., Cannan, A., Mullens, R., Dunphy, M., Pearson, T., Lau, C., Chipchase, L. The Effect of Interactive Neurostimulation Therapy on Myofascial Trigger Pints Associated with mechanical Neck Pain: A Preliminary Randomized, Sham-Controlled Trial. J Alt Compl Med. 18(10):946-952, 2012.

11. Aguggia, M., Saracco, M., Cavallini, M., Bussone, G., Cortelli, P. Sensitization and pain. Neurol Sci. 34(Suppl1):S37-S40, 2013.

12. Bari, A., Pouratian, N. Brain imaging correlates of peripheral nerve stimulation. Surg Neurol Int.3(Suppl4):S260-S268, 2012.

13. Cecchini, A., Leone, M., Tullo, V., Curone, M., DiFiore, P., Bussone, G. Occipital neurostimulation in primary headaches: update. Neurol Sci. 34 (Suppl1):S113-S115, 2013.

14. Lewis, John. A.T. Still From the Dry Bone to the Living Man. John Leis 2012. Dry Bones Press, GwyneddLL41 3YW.

15. Lv, X., Wu, Z., Li, Y. Innervation of the Cerebral Dura Mater. The Neurorad J. 27:293-298, 2014.

16. Krishnan, C., at al. Safety of Noninvasive Brain Stimulation in Children and Adolescents. Brain Stimulation. 8:76-87, 2015.