1Final Program

CME CREDITS

THE 12th REGIONAL MEETING OF THE LEBANESE SOCIETYOF HEMATOLOGY & BLOOD TRANSFUSION

Under The High Patronage of His ExcellencyThe President of the Lebanese Republic

GENERAL MICHEL AOUN

October 31, November 1-2, 2019Hilton Habtoor Hotel - Beirut - Lebanon

In Collaboration withEuropean Hematology Association

The Syndicate of Clinical Biologists in LebanonThe Order of Pharmacists in Lebanon

The Order of Nurses in Lebanon

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Table of Contents

Greetings from the President 3

General Information 4

Committees and Speakers 6

Scientific Program

• Physicians Thursday 31st October 2019 8 Friday 1st November 2019 10 Saturday 2nd November 2019 13

• Pharmacists Friday 1st November 2019 15

• Nurses Saturday 2nd November 2019 16

EBAH Accreditation 17

Acknowledgements 18

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Greetings from the President

Ahmad Ibrahim, MD President of the Congress President of the Lebanese Society of Hematology & Blood Transfusion

On behalf of the Lebanese Society of Hematology and Blood Transfusion (LSHBT) I am pleased and honored to invite you to the 12th Regional Meeting and Exposition of our Society.This year’s meeting will take place in the lovely and vibrant city of Beirut, the capital of Lebanon.

The objective of the meeting is to provide high educational input for trainees, physicians, scientists, pharmacists, nurses and industry professionals in hematology. Prestigious speakers from around the globe and regional experts have been invited to this forum with the aim of promoting scientific exchange and collaboration.

The meeting will be held in joint collaboration with the European Hematology Association (EHA).

All the sessions will be educational and classified per themes: in the fields of benign and malignant hematological diseases. Some sessions will be dedicated to biologists, pathologists, pharmacists and nurses.

I encourage you to browse the pages of the program to discover the diverse topics that will be covered this year.

I look forward to welcoming you in Beirut!

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General Information

Conference SecretaristTrust and Traders International SARL - Beirut

During the Conference the Secretariat can be contacted atPhone: +961 70 504 238 +961 03 226 208Email: executive3@trustandtraders.com

AccommodationIf you are still in need of a hotel room, please contact the conferencemanagement: Phone: +961 70 504 238Email: executive3@trustandtraders.com

BadgeKindly note that participants are requested to wear their badge at all times during the conference.

Conference LanguageThe conference language is English.There will be no translation into other languages.

InternetAll participants will have free access to High Speed Wireless Internet at the conference room at no extra cost.

RegistrationFull registration will include badge, congress bag, access to the scientificsessions and exhibition, coffee breaks and lunches, and a copy of the program.

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Speakers Ready RoomOn all the following conference days, the Speakers Ready Room is located inside the conference room.Speakers are requested to bring their PowerPoint presentations Format 16x9on a USB at least 3 hours before their session starts or the day before if thesession starts early in the morning and give them to the technician at theconference room. Only Windows PowerPoint files can be accepted. No laptoppresentations will be allowed in the session rooms.

Non-SmokingThere will be a strict non-smoking policy within all areas of the facilities used by the conference.

TransportationHilton Habtoor Hotel is 10 - 15 minute drive from Beirut Rafic Hariri International Airport, and approximately 10 minutes from downtown Beirut.

Conference RoomsPhysicians Program - Emirates Hall L2Pharmacists and Nurses Program - Beirut Hall & Hamra Hall - Convention Center L3

Registration & Exhibition L2

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Committees

President of the congress

Ahmad Ibrahim, MD

Organizing Committee

Chairperson

Peter Noun, MD

Members

Dani Abi Gerges, MDTherese Abou Nasr, MDMona Al Ayoubi, MDAdnan Atallah, MDAntoine Chahine, MDAhmad Chahrour, MDBerthe Chalhoub Hachem, MD, MHAIssam Chehade, MDFadi Farhat, MDOussma Jradi, MDAbdel Fattah El Kheir, MDHassan Khalifeh, MDClaudia Djambas Khayat, MDJawad Makarim, MDWalid Moukaddam, MDWajih Saad, MD Oussama Safar, MDHanady Samaha, MD, MHAAnthony Saroufim, MDAli Youssef, MD

Scientific Committee

Chairperson

Ali Taher, MD, PhD, FRCP

Members

Miguel R. Abboud, MD, MHAAbir Alame, MDAli Bazarbachi, MD, PhD, MHANizar Bitar, MDGeorges Chahine, MDNabil Chamseddine, MDJean El-Cheikh, MDMirna Germanos, MDHadi Ghanem, MDMohamad Haidar, MDColette Hanna, MDKhaled Ibrahim, MDAdlette Inati, MDJoseph Kattan, MDJoseph Makdessi, MDFadi Nasr, MDZiad Salem, MDAhmad Youness, MDMarc-Antoine Zablith, MD

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Speakers

Miguel Abboud Lebanon Ibrahim Yakoub-Agha France Kamal Al Zahran Lebanon Sahar Atieh Lebanon Ali Bazarbachi Lebanon Paul Bröckelmann Germany Maria-Domenica Cappellini Italy Jean-Hugues Dalle France Ghandi Damaj France Naval Daver USA Stephane De Botton France Philippe de Moerloose Switzerland Ismail Elalamy France Jean El Cheikh Lebanon Laetitia Federicie France Berthe Chalhoub Hachem LebanonJohn Gribben UK Hanan Hamed Egypt Audra Hannun Lebanon Jean-Luc Harousseau France Olivier Hermine France Elias Jabbour USA Wojciech Jurczak Poland Tapan Kadia USA Mohamad Kharfan Dabaja USA Rami Komrokji USA Hans Michael Kvasnicka Germany Achille Iolascon Italy Rami Mahfouz Lebanon Kelsey Moakler USA Mohamad Mohty France Peter Noun Lebanon Owen O’Connor USA Shilpa Paul USA Naveen Pemmaraju USA France Pirenne France Caitlin Rausch USA Giuseppe Saglio Italy Phillip Scheinberg Brazil Ana Maria Balari Sureda Spain Ali Taher Lebanon Ahmad Tassi Lebanon William Wierda USA

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Physicians Program

Thursday 31st October 2019

11h30-12h30 Registration 12h30 - 14h00 Thrombosis and Bleeding Chairs Roula Farah (Lebanon), Claudia Khayat (Lebanon), Malak Nabulsi (Lebanon), Peter Noun (Lebanon)

12h30 - 12h50 Management of HIT in 2019 Ismail Elalamy

12h50 - 13h10 Hemophilia and aging Philippe de Moerloose 13h10 - 13h30 Identification of thrombotic risk in cancer patients Ismail Elalamy

13h30 - 13h50 Rare bleeding disorders Philippe de Moerloose 13h50 - 14h00 Questions and Answers 14h00 - 15h30 Myeloproliferative Neoplasms Chairs Nizar Bitar (Lebanon), Issam Chehade (Lebanon), Salem El Shemmari (Kuwait), Mouin Fouani (Lebanon) 14h00 - 14h20 Updates on the classification of myeloproliferative neoplasms Hans Michael Kvasnicka 14h20 - 14h40 JAK2 inhibitors in polycythemia vera and essential thrombocythemia Naveen Pemmaraju 14h40 - 15h00 Management of advanced systemic mastocytosis in 2019 Gandhi Damaj 15h00 - 15h20 Management of myelofibrosis in 2019 Naveen Pemmaraju 15h20 - 15h30 Questions and Answers 15h30 - 16h00 Coffee Break 16h00 - 17h10 Hodgkin’s Lymphoma Chairs Samira Bouchama (Algeria), Ahmad Chahrour (Lebanon), Ahamad Younes (Lebanon) 16h00 - 16h20 First line treatment and response adapted therapy in Hodgkin’s lymphoma Ana Maria Balari Sureda 16h20 - 16h40 Treatment of relapsed/refractory Hodgkin’s lymphoma Paul Bröckelmann 16h40 - 17h00 Hematopoietic stem cell transplantation in Hodgkin’s lymphoma Ana Maria Balari Sureda 17h00 - 17h10 Questions and Answers

Emirates Hall

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Thursday 31st October 2019

Physicians Program

17h10 - 18h10 Debates Session (I) Chairs Hassan Ghazzal (Lebanon), Maha Manachi (Syria), Ahmad Ibrahim (Lebanon), Antoine Chahine (Lebanon)

17h10 - 17h40 Relapsed / Refractory Lymphoblastic Leukemia: Antibodies vs CAR-T Elias Jabbour , Mohamad Mohty 17h40 - 18h10 First line therapy for chronic lymphocytic leukemia: Chemoimmunotherapy vs chemo free / Targeted therapy John Gribben , William Wierda

18h10 - 19h00 Opening Ceremony & Cocktail Reception

The Lebanese National Anthem

• Word of welcome by the master of ceremony Dr. Peter Noun

• Address by the President of the Lebanese Society of Hematology and Blood Transfusion Pr. Ahmad Ibrahim

• Address by the President Elect of the European Hematology Association Pr. John Gribben

• Address by the President of the Hospitals in Lebanon Mr. Sleiman Haroun

• Address by the President of the Lebanese Order of Physicians in Beirut Pr. Charaf Abou Charaf

• Address by the President of the Lebanese Order of Physicians - Tripoli Dr. Salim Abi Saleh

• Address by the Minister of Public Health H.E. Dr. Jamil Jabak

• Address by the President of the Lebanese Republic H.E. General Michel Aoun

The ceremony will be followed by a visit of the technical and pharmaceutical exhibits and a cocktail reception

Emirates Hall

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Friday 1st November 2019

07h30 - 08h00 Registration

08h00 - 09h10 Transfusion MedicineChairs Rita Feghali (Lebanon), Christian Haddad (Lebanon), Hanady Samaha (Lebanon)

08h00 - 08h20 Alloimmunization against red blood cells in transfused patients with hematological disorders France Pirenne 08h20 - 08h40 National survey of transfusion centers to guide hemovigilance policies according to international recommendations Berthe Hachem 08h40 - 09h00 Interferences and management of pre-transfusion screening tests in new treatments of multiple myeloma France Pirenne 09h00 - 09h10 Questions and Answers

09h10 - 10h40 Non Hodgkin’s LymphomaChairs Georges Chahine (Lebanon), Oussama Safar (Lebanon), Raafat Soliman (Egypt), Mahmoud Wehbi (Lebanon)

09h10 - 09h30 Is R-CHOP standard front-line therapy for high risk diffuse large B cell lymphoma in the era of molecular driven therapy Owen O’Connor 09h30 - 09h50 Management of high risk follicular lymphoma in 2019 Wojciech Jurczak 09h50 - 10h10 Management of mantle cell lymphoma in 2019 Olivier Hermine 10h10 - 10h30 Management of T cell lymphoma in 2019 Owen O’Connor 10h30 - 10h40 Questions and Answers 10h40 - 11h00 Coffee Break 11h00 - 12h00 How I Treat Session (I) Chairs Hampig Kourie (Lebanon), Amar Lal (UAE), Ali Youssef (Lebanon)

11h00 - 11h20 How I treat myelodysplastic syndromes Rami Komrokji 11h20 - 11h40 How I treat acute myeloblastic leukemia Tapan Kadia 11h40 - 12h00 How I treat chronic myelogenous leukemia Elias Jabbour

Physicians Program

Emirates Hall

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12h00 - 13h10 Multiple Myeloma Chairs Hadjira Ahmidatou (Algeria), Adnan Atallah (Lebanon), Khaled Ibrahim (Lebanon)

12h00 - 12h20 Front line therapy for multiple myeloma Mohamad Mohty 12h20 - 12h40 Treatment of relapsed/refractory multiple myeloma Jean-Luc Harousseau 12h40 - 13h00 CAR-T for multiple myeloma Ibrahim Yakoub-Agha 13h00 - 13h10 Questions and Answers

13h10 - 13h35 KEY NOTE LECTUREChair Ziad Salem (Lebanon)

Hemoglobinopathies Ali Taher 13h35 - 14h30 Lunch 14h30 - 16h00 Targeted Therapy in Acute Myeloblastic LeukemiaChairs Alaa Alwan (Iraq), Khalid Halahleh (Jordan), Ziad Salem (Lebanon), Anthony Saroufim (Lebanon) 14h30 - 14h45 Targeting IDH1/IDH2 mutations Stephane De Botton 14h45 - 15h00 Targeting FLT3 mutations Naval Daver 15h00 - 15h15 Monoclonal antibodies Tapan Kadia 15h15 - 15h30 Targeting Bcl2 Naval Daver 15h30 - 15h50 Maintenance therapy after allogeneic BMT in acute myeloblastic leukemia Ali Bazarbachi 15h50 - 16h00 Questions and Answers 16h00 - 17h00 Debates Session (II)Chairs Ahmed Al Mashhadani (Iraq), Ali Bazarbachi (Lebanon), Haifaa Dbouk (Lebanon), Walid Moukadem (Lebanon) 16h00 - 16h30 Myelodysplastic syndromes: Front line allogeneic BMT for every fit patient vs No Front line allogeneic BMT for every fit patient Ibrahim Yakoub-Agha , Rami Komrokji 16h30 - 17h00 Acute lymphoblastic leukemia Ph+: Allogeneic BMT vs No allogeneic BMT Mohamad Mohty , Elias Jabbour 17h00 - 17h20 Coffee Break

Friday 1st November 2019

Physicians Program

Emirates Hall

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Friday 1st November 2019

17h20 - 17h45 KEY NOTE LECTURE Chair Ahmad Ibrahim (Lebanon)

CAR-T in hematological malignancies Mohamad Kharfan Dabaja 17h45 - 19h00 EHA Session on Minimal Residual Disease (MRD)Chairs John Gribben (UK), Ahmad Ibrahim (Lebanon)

17h45 - 18h00 MRD in acute lymphoblastic leukemia Elias Jabbour 18h00 - 18h15 MRD in acute myeloblastic leukemia Tapan Kadia 18h15 - 18h30 MRD in multiple myeloma Jean-Luc Harrousseau 18h30 - 18h50 MRD in chronic myelogenous leukemia and treatment free remission (TFR) Giuseppe Saglio 18h50 - 19h00 Questions and Answers

Physicians Program

Emirates Hall

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Saturday 2nd November 2019

07h30 - 08h00 Registration

08h00 - 09h10 Red Cell and Iron Chairs Hassan Khalifeh (Lebanon), Elie Khoury (Lebanon), Ali Taher (Lebanon)

08h00 - 08h20 Congenital dyserythropoiesis anemias Achille Iolascon 08h20 - 08h40 Iron deficiency across different diseases Maria-Domenica Cappellini 08h40 - 09h00 Red cell membrane abnormalities Achille Iolascon 09h00 - 09h10 Questions and Answers 09h10 - 09h50 How I Treat Session (II)Chairs Rami Abu Masmah (Jordan), Joseph Kattan (Lebanon), Joseph Makdessi (Lebanon) 09h10 - 09h30 How I treat acute lymphoblastic leukemia Elias Jabbour 09h30 - 09h50 How I treat chronic lymphocytic leukemia William Wierda 09h50 - 10h10 Coffee Break 10h10 - 11h30 How I Treat Session (III)Chairs Nidal Joumaa (Lebanon), Tamima Jisr (Lebanon), Oussama Jradi (Lebanon), Christina Khater (Lebanon) 10h10 - 10h30 How I treat ITP Ali Taher , Peter Noun 10h30 - 10h50 How I treat Aplastic Anemia Phillip Scheinberg 10h50 - 11h10 How I treat TTP Hanan Hamed 11h10 - 11h30 How I treat sickle cell disease Miguel Abboud

Physicians Program

Emirates Hall

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11h30 - 13h10 Acute Leukemia Chairs Dany Abi Gerges (Lebanon), Salam Al Kindi (Oman), Malek Baassiri (Lebanon), Colette Hanna (Lebanon) 11h30 - 11h50 NGS in acute leukemia: Knocking at the door of clinical practice Rami Mahfouz 11h50 - 12h10 Acute lymphoblastic leukemia in children Jean-Hugues Dalle 12h10 - 12h30 Acute myeloblastic leukemia in elderly Stephane De Botton 12h30 - 12h50 Haploidentical allogeneic BMT in accute leukemia Jean El Cheikh 12h50 - 13h10 Questions and Answers

13h10 - 14h10 Debates Session (III) Chairs Mona Ayoubi (Lebanon), Noufissa Dreideb (Morocco), Marcel Massoud (Lebanon), Fadi Nasr (Lebanon) 13h10 - 13h40 First line therapy for chronic myelogenous leukemia: Imatinib vs 2nd generation TKIs Guiseppe Saglio , Elias Jabbour 13h40 - 14h10 First line therapy for acute myeloblastic leukemia: 3x7 regimen vs other regimens or targeted therapy Stephane De Botton , Tapan Kadia

14h10 - 15h10 Lunch

Saturday 2nd November 2019

Physicians Program

Emirates Hall

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Chairs May Fakhoury (Lebanon), Marie-Gabrielle Ghorra Hindi (Lebanon), Noha Hakime (Lebanon)

09h00 - 09h25 Biosimilars in hematology: Understanding their role and how they differ from generics Shilpa Paul 09h25 - 09h35 Questions and Answers 09h35 - 10h00 Monitoring of Direct Oral Anticoagulants (DOACs) Ismail Elalamy 10h00 - 10h10 Questions and Answers 10h10 - 10h35 Management of toxicities with new targeted therapies in acute myeloblastic leukemia Shilpa Paul 10h35 - 10h45 Questions and Answers 10h45 - 11h15 Brunch Chairs Diane Antonios (Lebanon), Myrna Germanos (Lebanon), Lucine Halipian (Lebanon)

11h15 - 11h40 Management of treatment in acute lymphoblastic leukemia: Focus on hyper-CVAD and antibodies Caitlin Rausch 11h40 - 11h50 Questions and Answers 11h50 - 12h15 Keeping drug use safe over 65 years old: The updated Beers criteria Audra Hannoun 12h15 - 12h25 Questions and Answers 12h25 - 12h50 Drugs and blood-brain barrier Laetitia Federicie 12h50 - 13h00 Questions and Answers

Friday 1st November 2019

Pharmacists Program

Beirut Hall Hamra Hall

ConventionCenter

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Saturday 2nd November 2019

Nurses Program

Chairs Rima Nehme (Lebanon), Ammar Zahreddine (Lebanon)

08h30 - 09h00 Role of nurses in hematology: Focus on treatment Kelsey Moakler 09h00 - 09h10 Questions and Answers 09h10 - 09h40 Multidisciplinary approach for complications after allogeneic hematopoetic stem cell transplantation Kamal Al Zahran 09h40 - 09h50 Questions and Answers 09h50 - 10h20 Brunch

Chairs: Shams Issa (Lebanon), Ahmad Tassi (Lebanon)

10h20 - 10h50 Patient safety for hematology patients Ammar Zahreddine 10h50 - 11h00 Questions and Answers 11h00 - 11h30 Role of the nurses in the management of tumor lysis syndrome Kelsey Moakler 11h30 - 11h40 Questions and Answers 11h40 - 12h10 Safe blood transfusion between human errors and clinical malpractices Ahmad Tassi 12h10 - 12h20 Questions and Answers 12h20 - 12h50 Keeping patients safe: All we need to know while caring for neutropenic patients Sahar Atieh 12h50 - 13h00 Questions and Answers

Beirut Hall Hamra Hall

ConventionCenter

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EBAH Accreditation

The program of the 12th regional meeting of the lebanese society of hematology & blood transfusion has been reviewed and approved for CME accreditation by the European Board for Accreditation in Hematology (EBAH). The EBAH has approved this educational activity for a maximum number of [26]CME credits. Each physician should only collect credits for time that she/he actually spent in the educational activity.

Instructions on how to collect the CME credit points for this activity: In order to make sure you obtain CME credit points, you must have an account at the EBAH online system at www.ebah.org

Visit the website: www.ebah.org and create a CME account for yourself by clicking the red button: simple procedure and free of cost.

CME

• LOP-CME: LOP card mandatory upon registration • EBAH-CME: to be obtained online after congress

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Platinum Sponsors

Gold Sponsors

Silver Sponsors

Acknowledgements

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Contributors

Registration fees

LSHBT members FreeLebanese physicians $50.00Residents and students FreeNon Lebanese doctors $400.00Nurses Free (mandatory pre-registration)Pharmacists Free (mandatory pre-registration) Include• Access to scientific sessions and exhibition area• CME accreditation• Certificate of attendance• Congress bag• Coffee breaks and lunches

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