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Volume 12 Metastatic carcinoma----------Case 1122-1169

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Page 1: Vol 12 ppt

Volume 12

Metastatic carcinoma----------Case 1122-1169

Page 2: Vol 12 ppt

Case #1122

54 year male with prior

history of metastatic renal

cell CA to proximal femur

with DHS & cement fixation

and post op radiation therapy

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One year later with

recurrent tumor

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Surgical specimen

following wide resection

proximal femur

tumor

bulge

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Photomic

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Autoclaved prox femur

placed over long stem

femoral component

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Cemented back in

normal anatomic position

with THA

osteotomy

cement

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5 months post op with

radiolucent cement

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18 months post op

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Case #1124

58 year male with metastatic renal cell CA to pelvis

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Post op treatment with

radiolucent cement

THA and radiation therapy

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Case #1125

65 year male with path fracture thru metastatic renal cell CA

in sciatic notch area

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Case #1126

48 year male with large

hemorrhagic renal cell

CA distal humerus

tumor

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Case #1127

66 year male with

metastatic renal cell CA

post op ORIF, pin

fixation and post op RT

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Case #1128

61 year female with metastatic renal cell CA hip area

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Lytic lesion in clavicle

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Multiple lesions in both hands

Metastatic Renal Cell

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Case #1128.1

57 year male with renal cell CA metastasis to fibular

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6 months later without treatment

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Bone scan

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Sagittal T-2 MRI

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Photomic

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Case #1129

61 year female with metastatic aneurysmal

renal cell CA to distal tibia

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Photomic

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Case #1130

45 year male with metastatic renal cell CA to os calcis

Metastatic Renal Cell

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Sagital T-1 MRI

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Sagittal T-2 MRI

tumor

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Axal T-1 MRI

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Axial T-2 MRI

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Photomic

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Case #1131

54 year female with metastatic aneurysmal thyroid to pelvis

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CT scan

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Case #1132

45 year female with lytic thyroid metastasis to pelvis

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Rapid progression without treatment 6 months later

tumor tumor

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Case #1133

52 year female with metastatic thyroid CA to pelvis

MetastaticThyroid

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Case #1134

54 year female with metastatic thyroid CA to pelvis

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Case #1135

48 yr male with metastatic blastic thyroid met to femoral neck

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Bone scan

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Case #1135.1

21 year female with large pelvic mass which turned out to be

a metastatic thyroid metastasis from an ovarian teratoma

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Pelvic metastasis seen on PO x-ray following teratoma surgery

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Bone scan

tumor

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Sciatic notch level

tumor

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Supra acetabular level

tumor

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I-131 isotope scan prior to teratoma surgery shows

uptake in both the ovarian teratoma and pelvic met

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Surgical specimen from resection of pelvic metastasis

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Photomic from thyroid metastasis

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Placement of multiple Steinman pins prior to cementation

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Bone cement placed over pins

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Post op reconstruction with pins and cement

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Case #1136

65 year female with old rh arth with multi THA’s and current

pseudoarthrosis; on coumadin and painful lytic lesion ilium

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CT scan looks like metastatic hemorrhagic thyroid or renal CA

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Axial T-1 MRI shows large iliac hematoma and at biopsy

no tumor was found

hematoma

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Axial T-2 MRI showing large hemorrhagic pseudotumor

old hemorrhage

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Case #1137

91 year female with aneurysmal pseudotumor of sternum thought

to be metastatic renal or thyroid met; instead an aortic aneurysm

blood

CT scan

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Case #1138

70 year male with metastatic blastic prostate R hemipelvis

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Bone scan

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Photomic showing reactive osteoid formation

tumor

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Case #1138.1

84 year male with pathologic

fracture humerus 2nd to

metastatic lytic form of

prostate CA

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Case #1139

72 year male with blastic prostate mets to pelvis & L-spine

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Photomic

osteoid

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Case #1140

79 year male with painless blastic mets to pelvis & prox femur

Metastatic prostate

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Photomic showing reactive osteoid

tumor

osteoid

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Case #1141

83 year male with lytic

prostate metastasis to

C-2

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Lateral laminogram

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Photomic

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Case #1142

38 year male with metastatic testicular CA & path fracture

right proximal femur

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Bone scan showing

multiple mets to ribs,

pelvis, spine, shoulder,

and femur

R

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Rconstruction with cemented bipolar implant and RT

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Sagittal T-1 MRI

showing multiple mets

to L-spine

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Case #1143

73 year male with lytic lung met to the intercondylar area

Metastatic Lung

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Lateral view

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Bone scan

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Coronal T-1 MRI

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Coronal T-2 MRI

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Axial T-1 MRI

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Sagittal T-1 MRI

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Sagittal T-2 MRI

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Chest x-ray showing primary lung CA

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Case #1143.1

55 year male with

subtroch path fracture

2nd to metastatic lung CA

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Lateral view

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Case #1144

55 year female with

metastatic lung CA

to distal tibia

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Chest x-ray showing primary lung CA

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Case #1145

37 year male with metastatic lung CA to pelvis

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CT scan

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Coronal T-1 MRI

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Axial T-2 MRI

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Case #1146

43 year male with

metastatic lung CA

to distal humerus

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Lateral view

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Chest x-ray showing primary lung CA right apex

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Case #1147

46 year male with central fracture dislocation thru metastatic

lung CA of left peri-acetabular area

Metastatic Lung

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Post op appearance following

modified internal hemipelvec-

tomy with cement and pins

with THA

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Case #1148

58 year male with

metastatic squamous

cell CA from right

thigh skin to right

supra-acetabular area

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Post op appearance following an internal hemipelvectomy

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Case #1149

43 year female with

metastatic lung to

distal fibula

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Case #1150

44 year male with metastatic lung to distal thumb

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AP view

Page 97: Vol 12 ppt

Case #1151

46 year male with metastatic rectal CA to acetabulum

Metastatic Rectal Carcinoma

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Post op appearance following

cemented THA

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Acetabular biopsy photomic

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Case #1152

49 year female with blastic rectal CA metastasis to pelvis

Rectal Carcinoma

Page 101: Vol 12 ppt

Case #1153

67 year male with colon metastasis to toes with prior amp

Colon CA

Page 102: Vol 12 ppt

Case #1154

74 year female with

metastatic abdominal

carcinoid to humerus

Abdominal Carcinoid to Bone

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Post op cemented

IM nail

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Case #1155

62yr male with metastatic hepatoma prox femur with fracture

Metastatic Hepatoma

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Lateral view

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Post op ORIF

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Mets to lung as well

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Case #1155.1 Metastatic Hepatoma

9/9 9/26 10/21

51 yr male with pain 3 wks prior to fracture of humerus

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Axial T-1 MRI Bone scan

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CT of liver showing primary hepatoma lesion

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Case #1156

49 year female with metastatic gallbladder CA to skull

Metastatic Gallbladder

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Photomic skull biopsy

Page 113: Vol 12 ppt

Case #1157

63 year male with prior

history of spine fusion

and recent pancreatic

CA met to L-5

Pancreatic Carcinoma to Bone

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Photomic from L-5 biopsy

Page 115: Vol 12 ppt

Case #1158

69 year male with

metastatic transitional

bladder CA to femur

Transitional Bladder CA

Page 116: Vol 12 ppt

Cae #1159

66 year male with metastatic

transitional bladder CA

to femur with path fracture

Transitional Bladder CA to Bone

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Axial T-2 MRI showing

metastatic transitional

CA to brain

Page 118: Vol 12 ppt

Case #1160

52 year female with metastatic cervical CA to R hemipelvis

Cervical CA

Page 119: Vol 12 ppt

Case #1161

54 year female with endometrial CA uterus to pelvis

Endometrial CA

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One year later without treatment

tumor

heterotopic ossification

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Photomic from pelvic metastatsis

osteoid

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photomic of endometrial adenocarcinoma

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Case #1161.1

57 year female with leg and heal pain for one year

Endometrial CA

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Post op cemented IM nail

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Case #1161.2 Endometrial CA

63 yr female with prior history of endometrial CA

Page 126: Vol 12 ppt

Case #1162

27 year male with path

fracture thru metastatic

melanoma from thigh

skin where he had a

resection 4 yrs ago

Metastatic Melenoma

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Black pigmentation in biopsy specimen

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Post op fixation with

cemented IM nail

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Case #1162.1

29 year male with pain left hip for 6 weeks

Metastatic melanoma

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Post op x-ray

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Case #1163

53 year female with

metastatic breast CA

right shoulder

Metastatic Breast

Page 132: Vol 12 ppt

Biopsy specimen showing neoplastic induced osteoclysis

Page 133: Vol 12 ppt

Case #1163.1 Metastatic Breast looking like Bone Islands

54 yr female with history of breast CA 7 yrs ago

Page 134: Vol 12 ppt

Case #1164

16 year male with bone

island proximal femur

looking like a blastic

metastasis

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CTscan

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Coronal T-2 MRI

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Axial T-2 MRI

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Macro section of resected bone island specimen

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Case #1165

45 year female with multiple bone islands looking like mets

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Case #1166

35 year male with bone island ilium looking like a

blastic metastatsis

CT scan

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Axial T-2 MRI

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Case #1167 CT scan

56 year female with bone island looking like blastic metastasis

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Negative bone scan suggests a pseudotumor diagnosis

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Case #1168

43 year female with

vertebral bone island

looking like a blastic

metastasis

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Case #1168.1

55 year male with workup for possible bone metastasis

Bone scan

Bone island

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Cor T-1 STIR Gad

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Case #1169

47 year female with stress fracture femoral neck looking like

a blastic metastasis

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Bone scan showing hot

spot left rib and right hip

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Photomic hip biopsy showing callous formation

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Photomic showing callous formation

Page 151: Vol 12 ppt

Post op bipolar prosthesis

because surgeon thought

patient had metastatic

disease when in fact the

femoral lesion and the

rib fracture are osteoporotic

pseudotumors

Page 152: Vol 12 ppt

Case #1169.1

43 yr female on steroids for lupus with bilat hip pain for 6 months

Stress fractures

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Bone scan

Page 154: Vol 12 ppt

Cor T-1

PD

Page 155: Vol 12 ppt

Axial PD