· web viewintroduction to experimental pharmacology types, methods and conditions of bioassay...

34
0 Mansoura University Faculty of Medicine Assistant

Upload: others

Post on 16-Mar-2020

0 views

Category:

Documents


0 download

TRANSCRIPT

Page 1:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

0

Personal Data

Mansoura UniversityFaculty of Medicine

Assistant Lecturer

Page 2:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Name: ………………………………………………………………

Date of Birth: …………………………………………

Home Address: ………………………………………………………………

Telephone Number: ………………………………………………………

E-mail Address: ………………………………………………………

M.B., B. Ch.: Date: ………………………………………

Degree: ………………………………………

Present Job: Work address: Mansoura University, Faculty of Medicine, Clinical

Pharmacology Dept. Date of appointment: ………………………………

Master Degree: Date of registration: ………………………………

Date of graduation (1st part): ………………

Date of discussion of thesis: ………………

Date of graduation (2nd part): ………………

Final degree: ………………………

MD Degree: Date of registration: ………………………………

Date of graduation (1st part): ………/………/…………

Date of graduation (2nd part): ………/………/…………

Date of discussion of thesis: ………/………/…………

Final degree: ……………………………………

Head of the Department Vice Dean for research and postgraduate study

Prof. Dr. Somaia Abdulatef Mokbel

1

Put your picture here

Page 3:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Assistant Lecturer:A. MD Degree Course:

Scientific Lectures (1st part) Practical Training Courses (1st part) Scientific Lectures (2nd part) Practical Training Courses (2nd part)

B. Master Degree ThesisC. Scientific Activities:

Seminars Conferences Thesis Discussion Training Courses and Workshops

D. Other Activities at the Department: Student Sections Others

A. MD Degree Course:Scientific Lectures (1st part): 1st semester (General Pharmacology)

2

Assistant Lecturer

Contents

Page 4:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Date Title SupervisorDrug transportDrug receptorsPharmacodynamicsPharmacokineticsPharmacokineticsAdverse reactions & pharmacogeneticsDrug interactionsDrug toxicityDrugs and geriatricsDrugs and pediatricsDrugs and pregnancyDrugs and diseasesDrug development and regulation Principles of prescription writingOTC, Alcohols, drug addiction & abuse

3

Page 5:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Scientific Lectures (1st part): 1st semester (Bioassay)

Date Title SupervisorIntroduction to experimental Pharmacology Types, methods and conditions

of bioassay (biological variability)

Characteristics & housing of laboratory animals

laboratory animals in experimental pharmacology

Administration of drugs to laboratory animals

Animal toxicity studiesPhysiological salt solutions, units, levers. Standard techniques of collection of bloodBioassay of agonists and antagonistsScreening for drugs treating peptic ulcerScreening for histamine & antihistaminicsScreening for analgesics and anti-inflammatoryScreening for antidepressantsScreening for serotonin& antipsychoticsScreening for anticonvulsants & antiparkinsoninsScreening for local anestheticsScreening for antialzheimerScreening for antidiabeticsScreening for Diuretics & antihypertensiveScreening for chemotherapy (Antibacterial & anticancer)

4

Page 6:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

5

Page 7:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Scientific Lectures (2nd part): 3rd semester (Basic Pharmacology)

Date Title SupervisorDrugs affecting the renin angiotensin system, Drugs affecting the Calcium channels, Vasodilators Sympathoplegics, Centrally acting antihypertensiveNitrates, beta blockers, CCB, and newer drugs modulating cardiac ischemia.Drugs affecting transmembrane ionic transportCardiotonic drugs.Antiarrhythmic drugs.Bronchodilators, anti-inflammatory, & leukotreine antagonistsAnticoagulant drugs, Thrombolytic drugs. Drugs affecting platelet function.Drugs affecting the hematopoietic systemDrugs affecting dyslipidemiasDrugs affecting CNS synapses and neurotransmitters.Opioid analgesics & antagonists, other analgesicsBasic pharmacology of Sedative-hypnoticsBasic pharmacology of antipsychotics & antidepressantsHistamine, 5-HT, peptides, serotonin, ergot alkaloids, Nitric oxide, Eicasanoids, and NSAIDsPuirnes and cannabinoidsDrugs affecting urine formation (diuretics & aquaretics)Drugs affecting renal transportersGeneral anesthetics & skeletal muscle relaxantsLocal anesthetics

6

Page 8:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

7

Page 9:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Scientific Lectures (2nd part): 3rd semester (Clinical Pharmacology)

Date Title SupervisorPharmacotherapy of Heart failurePharmacotherapy of Ischemic heart diseasePharmacotherapy of arterial hypertensionPharmacotherapy of ArrhythmiaPharmacotherapy of asthma & COPDPharmacotherapy of Pulmonary hypertension.Pharmacotherapy of Shock and Cardiopulmonary arrestPharmacotherapy of StrokePharmacotherapy of multiple sclerosisPharmacotherapy of Venous thromboembolismPharmacotherapy of Pulmonary embolism Pharmacotherapy of dyslipidemiaManagement of PainPharmacotherapy of HeadachePharmacotherapy of Parkinson's disease & other movement disordersPharmacotherapy of Alzheimer's diseasePharmacotherapy of EpilepsyPharmacotherapy of anxiety & insomniaPharmacotherapy of psychosis & maniaPharmacotherapy of depressionPharmacotherapy of Acute renal failurePharmacotherapy of Chronic kidney diseasePharmacotherapy of Urinary incontinenceDrug dosing in renal insufficiency

8

Page 10:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Pharmacotherapy of Erectile dysfunction

9

Page 11:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Practical training courses (2nd part): 3rd semester (Basic Pharmacology)

Date Title SupervisorGuinea pig ileumGuinea pig tracheal chainGuinea pig atriaEpinephrine-induced arrhythmiaRat uterusHot plate methodTail clip methodPaw compression methodStraub tail method

Practical training courses (2nd part): 3rd semester (Clinical Pharmacology)

Date Title SupervisorCase scenario (CVS)Case scenario (CVS)

10

Page 12:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Case scenario (CVS) Case scenario (CVS)Case scenario (CVS)Case scenario (blood)Case scenario (blood)Case scenario (CNS)Case scenario (CNS)Case scenario (CNS)Case scenario (CNS)Case scenario (CNS)Case scenario (renal)Case scenario (renal)Case scenario (renal)

Scientific Lectures (2nd part): 4th semester (Basic Pharmacology) Date Title Supervisor

Basic hormones & drugs controlling energy balanceDrugs affecting the reproductive systems (Hormones & inhibitors) Thyroxin & anti-thyroid drugsPancreatic hormones & antidiabetic drugsHypothalamic & pituitary hormones

11

Page 13:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Corticosteroids & antagonistsDrugs affecting Calcium & phosphorus hemostatsis.Antibacterial drugs -1Antibacterial drugs -2Antiparasitic drugs (antihelminthics)Antiprotozoal drugsAntiviral drugsAntifungal drugsMembrane transporters & drug responseCell proliferation , apoptosis, repair & regenerationCancer chemotherapyHormonal modulation of cancer & targeted therapies

Scientific Lectures (2nd part): 4th semester (Clinical Pharmacology)

Date Title SupervisorPharmacotherapy of Metabolic syndromePharmacotherapy of Diabetes mellitusPharmacotherapy of pituitary disordersContraception & Pharmacotherapy of Obstetrical & Gynecological disordersPharmacotherapy of menopause & osteoporosisPharmacotherapy of thyroid & adrenal disorders

12

Page 14:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Pharmacotherapy of Respiratory tract infections & TBPharmacotherapy of GIT & UT infectionsPharmacotherapy of Bone & soft tissue infections (e.g., Osteomyelitis)Pharmacotherapy of CNS infections (e.g., Meningitis)Pharmacotherapy of CV infections (e.g., Endocarditis)Medical & surgical antimicrobial prophylaxisPharmacotherapy of Parasitic diseasesPharmacotherapy of Sexual transmitted infectionsPharmacotherapy of AIDSPharmacotherapy of Viral infectionsPharmacotherapy of fungal infectionsPharmacotherapy of Infections in immunocompromized patientsGeneral management of CancerPharmacotherapy of Cancer breast & prostatePharmacotherapy of Leukemia & LymphomaPharmacotherapy of GIT cancers (HCC, & cancer colon)

13

Page 15:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Practical training courses (2nd part): 4th semester (Basic Pharmacology)

Date Title SupervisorAdjuvant-induced arthritisPTZ-induced convulsionTail suspension testAntagonism of perphenazine-induced catatonia in ratsSTZ-induced diabetesAlloxan-induced diabetesRighting reflexAcetic acid-induced writhing

Practical training courses (2nd part): 4th semester (clinical pharmacology)

Date Title SupervisorCase scenario (endocrine)

14

Page 16:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Case scenario (endocrine)Case scenario (endocrine)Case scenario (endocrine)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (chemotherapy)Case scenario (cancer chemotherapy)Case scenario (cancer chemotherapy)Case scenario (cancer chemotherapy)Case scenario (cancer chemotherapy)

Scientific Lectures (2nd part): 5th semester (Basic Pharmacology)

Date Title SupervisorBasic pharmacology of drugs affecting the GITLocal hormones: Histamine, 5-HT, peptides, serotonin, & ergot alkaloids, cytokines, peptides, prostanoids, & Nitric Oxide

15

Page 17:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Eicasanoids, and NSAIDsEnvironmental & occupational toxicology Heavy metals & chelatorsPharmacological studies in humans & clinical trialsPharmacogenetics, genomics & personalized medicineDrug-induced renal diseaseImmuosuppressive drugs & immunostimulantsVitaminsDietary supplement & herbal medicationsDrug-induced sexual dysfunctionIV Fluids & electrolytesBasic drugs acting on the eyeDrug-induced ocular disorders

16

Page 18:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Scientific Lectures (2nd part): 5th semester (Clinical Pharmacology)

Date Title SupervisorPharmacotherapy of NAFLD & NASH Pharmacotherapy of Irritable bowel syndromeDrug-induced liver diseases Prescribing in hepatic patients Pharmacotherapy of Peptic ulcer and upper GIT bleedingPharmacotherapy of Inflammatory bowel diseaseManagement of poisoned patients & antidotesPharmacotherapy of Rheumatoid arthritis, osteoarthritis, & goutPharmacotherapy of autoimmune disorders (e.g., Systemic lupus)Pharmacotherapy of skin disorders Drug-induced skin diseaseRegenerative medicine & stem cell medicinePrescribing in renal patientsParenteral nutrition Evidence based medicine.Life style drugs & drugs in sportPharmacotherapy of acid base and electrolyte disturbance.

17

Page 19:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Practical training courses (2nd part): 5th semester (Basic Pharmacology)

Date Title SupervisorImmobilization stress-induced ulcerIndomethacin- induced ulcerAnimal models of cerebral ischemiaAnimal models of Renal ischemiaAnimal models of hepatic ischemiaAnimal models of osteoarthritisScreening for drug toxicityScreening for drug toxicityScreening for drug teratogenicityScreening for immunosuppressive drugsScreening for immunosuppressive drugsRadioimmunoassay techniqueELISA technique

18

Page 20:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Practical training courses (2nd part): 5th semester (Clinical Pharmacology)

Date Title SupervisorCase scenario (GIT)Case scenario (liver)Case scenario (GIT)Case scenario (liver)Case scenario (toxicology)Case scenario (toxicology)Case scenario (immunology)Case scenario (immunology)Case scenario (dermatology)Case scenario (dermatology)Case scenario (dermatology)Case scenario (dermatology)Case scenario (dermatology)Case scenario (parenteral nutrition)Case scenario (life style)

Scientific Lectures (2nd part): 6th semester Date Training Subject Supervisor

Genes as drugsPharmacokinetics and pharmacodynamics

19

Page 21:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Tissue engineeringAntiproliferative gene therapyImmunostimulatory therapy Gene suppressionGene repair Oncolytic virotherapyClinical status and prospects

20

Page 22:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

B. MD Degree Thesis:

Title: ………………………………………………………..…………………………………………………………

………………………………………………………………………………………………………………………

Supervisors:……………………………………………..……………………………………………………………………………….……………………………………………………………………………………………………

………………………………………………………………………………………………………………………… ………………………………………………………………………………………………………………………… …………………………………………………………………………………………………………………………

…………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..……………

Summary of the Thesis: …………………………………………………………………………..

………………………………………………………………………………………………………………..……………… ……………………………………………………………………………………………………………………………… ……………………………………………………………………………………………………………….…………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………..……………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………….……………………………………………………………………....……………

C.Scientific Activities:Seminars:

Date Subject Supervisor

21

Page 23:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Conferences: Date Conference Supervisor

22

Page 24:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Thesis Discussion: Date Thesis discussed Supervisor

23

Page 25:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

Training Courses and Workshops: Date Training Subject Supervisor

24

Page 26:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

D. Other Activities at the Department:Student Sections:

Date Section Subject Supervisor

25

Page 27:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

.

Date Section Subject Supervisor

26

Page 28:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

.

Others: Date Activity Supervisor

.

27

Page 29:  · Web viewIntroduction to experimental Pharmacology Types, methods and conditions of bioassay (biological variability) Characteristics & housing of laboratory animals laboratory

28