welcome to institut pasteur! - paris nash
TRANSCRIPT
Welcome to Institut Pasteur!
Stanislas Pol, MD, PhD
Liver Department, Hôpital Cochin
Inserm U-1213 & Center for Translational Science, Institut Pasteur
Université Paris Descartes, Paris, France
Institut Pasteur: a research institute
4 missions to serve scientific progress and health
• Research
• An international research institute of excellence in medicine, clinical
research and public health
• Health and public health
• A mission of public health with (15 CNR et 9 CCOMS) at national and
international levels (health watch, alerts and interventions)
• Education
• A teaching and training centre
• Research applications
Technology transfer and industrial relations
Institut Pasteur: a research institute An original economic model: Independence in
research directions and reactivity
€296.4 M Current income in 2014
€88.2 M Research
contracts and
agreements
€39.6 M Industrial
royalties
€18.1 M€ External services
€145.9 M
Revenue from
own activities
49.2%
€87.1 M
Public gifts & donations
and revenues from
assets
€54.8 M
French Ministry of
Research
29.4%
€33.3 M Donations
€17.3 M Legacies
€35.3 M Revenues from assets
€1.2 M Apprenticeship tax
€3.5 M French Institute for
Public Health
Surveillance (InVS)
€58.3 M€
Government
contributions
19.7% 1.7%
€5.1 M
€5.1 M
Other income
The Institut Pasteur is a nonprofit organization and relies on the generosity and support of the public to carry out its research programs.
Institut Pasteur: a research institute
• Pr Christian Bréchot
- Director of IP: 2013-2017
- EASL secretary
- Very famous Hepatologist:
HBV:
first genomic diagnosis (Hybridotest)
first demonstration of direct hepatocarcinogenesis
Institut Pasteur: a research institute
11 departments in Paris 33 institutes in the Network
Vir
olo
gy
De
ve
lop
me
nt
Neu
roscie
nces
Gen
om
es
Etc
.
Cam
bo
dia
Sen
eg
al
Mo
rocco
Cam
ero
on
Etc
.
2015 : Creation of transversal centers
4
Institut Pasteur: An international institute at the
very heart of Paris
130
research
units 2,500
employees
650 scientists
4 transversal
research
centers
1,000
Ph students
and
postdocs
per year
11 scientific
departments
more than
60
nationalities
A 55,000 m2 campus
14
technological
platforms
Center for translationnal science
An integrated view of translational research: « guichet unique »
Center for translationnal science
An integrated view of translational research: « guichet unique »
Hospital Bedside
Translation
Research
Lab Bench
Center for translationnal science
Center for translationnal science
JRT Séminaire techno
(CRT-TC)
Matinales (CRT-CC) ¼ h Med ¼ h Science
Rassembler les acteurs de la rech.
translationnelle
Informer sur les nouvelles technologies
Informer sur la recherche clinique
Donner une culture médicale aux chercheurs
Faire connaître la recherche de l'IP dans
les hôpitaux
1/an (200p) 8/an (8p) 5/an (30p) 20/an (50p) 5/an à l’hôpital (10p)
Clémentine Schilte
Breakthrough session Storm
Patients et chercheurs (avec CRT-IB) Évènement social
Faciliter de nouvelles collaborations avec le
réseau
Rassembler médecins et chercheurs sur une
thématique
Réflexion sur la place des patients dans la recherche
Créer des liens entre médecins et chercheurs
1/an (100p) 1 ou 2/an (40p) 1/an (80p) 1/an (50p)
NASH: A multidisciplinary translationnal topic
- Hepatologist/Endocrinologist/Cardiologist/Nutritionnist/Surgeons… - Scientists of liver disease, metabolism pathways, imaging…
NASH: A multidisciplinary translationnal topic
Rinella, Nature rev. 2016
Unmet needs
- Noninvasive diagnosis of NASH
- Biomarkers of
progression of fibrosis
- Combination therapies
- Hepatologist/Endocrinologist/Cardiologist/Nutritionnist/Surgeons… - Scientists of liver disease, metabolism pathways, imaging…