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S epsis FACTS Sepsis arises when the body’s response to an infection injures its own tissues and organs. It may lead to shock, multi-organ failure, and death – especially if not recognized early and treated promptly. Sepsis is the final common pathway to death from most infectious diseases worldwide, including viruses such as SARS-CoV-2. At least 11 million deaths per year 2 47 – 50 million cases per year 1 1 in 5 deaths worldwide is associated with sepsis 3 September 13 You can help #StopSepsis and #SaveLives Get involved at worldsepsisday.org References 1, 2, 3, 8, 10 Rudd et al, https://doi.org/10.1016/S0140-6736(19)32989-7. 4 Rhee et al, https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2724768 5 Torio et al, https://www.hcup-us.ahrq.gov/reports/statbriefs/sb204-Most-Expensive-Hospital-Conditions.pdf 6 Buchman et al, https://journals.lww.com/ccmjournal/Fulltext/2020/03000/Sepsis_Among_Medicare_Beneficia- ries__3__The.4.aspx 7 Prescott et al, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839473/ 9 Rhee et al, https://jamanetwork.com/journals/jama/fullarticle/2654187 11 Seymour et al, https://www.nejm.org/doi/10.1056/NEJMoa1703058 40% of cases are children under 5 8 Up to 50% of sepsis survivors suffer from long-term physical and/or psychological effects 7 $ 1 Sepsis is the number • Cause of death in hospitals 4 • Cause for hospital readmissions 5 • Healthcare cost 6 SEPSIS is always caused by an infection like pneumonia or diarrheal illness 10 80% of sepsis cases occur outside of a hospital 9 SEPSIS is a medical emergency - if you or someone you know shows signs of sepsis, seek medical care immediately. Every hour counts. 11 These signs may indicate sepsis These signs may indicate sepsis: : w Ä#rÖzYx 4 ü* H Ö 6Yj S Slurred Speech lurred Speech or Confusion or Confusion E Extreme Shivering xtreme Shivering or or Muscle Muscle Pain Pain /Fever /Fever P Passing No assing No Urine Urine All Day All Day S Severe evere Breathlessness Breathlessness I It Feels Like t Feels Like You‘re Going You‘re Going to Die to Die S Skin Mottled kin Mottled or Discolored or Discolored (e.g. $62 billion is spent on sepsis healthcare costs in the US alone) Last updated: November 2020

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Page 1: Sepsis

Sepsis

FACTS

Sepsis arises when the body’s response to an infection injures its own tissues and organs. It may lead to shock, multi-organ failure, and death – especially if not recognized early and treated promptly. Sepsis is the final common pathway to death from most infectious diseases worldwide, including viruses such as SARS-CoV-2.

At least

11million

deaths per year

2

47 – 50 million

casesper year1

1 in 5 deaths worldwide isassociated

with sepsis3

September 13You can help #StopSepsis and #SaveLives Get involved at worldsepsisday.org

References1, 2, 3, 8, 10 Rudd et al, https://doi.org/10.1016/S0140-6736(19)32989-7.

4 Rhee et al, https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2724768

5 Torio et al, https://www.hcup-us.ahrq.gov/reports/statbriefs/sb204-Most-Expensive-Hospital-Conditions.pdf

6 Buchman et al,https://journals.lww.com/ccmjournal/Fulltext/2020/03000/Sepsis_Among_Medicare_Beneficia-ries__3__The.4.aspx

7 Prescott et al,https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839473/

9 Rhee et al,https://jamanetwork.com/journals/jama/fullarticle/2654187

11 Seymour et al,https://www.nejm.org/doi/10.1056/NEJMoa1703058

40%of cases

are children

under 58

Up to 50% of sepsis survivors

suffer from long-term physical and/or

psychological effects7

$1Sepsis is the number

• Cause of death in hospitals4

• Cause for hospital readmissions5

• Healthcare cost6

SEPSIS

is always caused by an

infection like pneumonia ordiarrheal illness10

80%of sepsis cases

occur outside

of a hospital9

SEPSIS is a medical emergency - if you or someone you know shows signs of sepsis, seek medical care immediately.

Every hour counts.11

These signs may indicate sepsisThese signs may indicate sepsis::w

Ä#rÖzYx4ü*

HÖ6Yj

SSlurred Speech lurred Speech or Confusionor Confusion

EExtreme Shivering xtreme Shivering oror MuscleMuscle PainPain

/Fever/Fever

PPassing No assing No Urine Urine

All DayAll Day

SSevere evere BreathlessnessBreathlessness

IIt Feels Like t Feels Like You‘re Going You‘re Going

to Dieto Die

SSkin Mottled kin Mottled or Discoloredor Discolored

(e.g. $62 billion is spent on sepsis healthcare costs in the US alone)

Last updated: November 2020

Neonatal Sepsis (Sepsis Neonatorum) medical management not included

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