www.uk-cpi.com © & confidential to the centre for process innovation ltd the centre for process...
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www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd
The Centre for Process Innovation
Wilton, Redcar
www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd
The Strategy for Success
www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd
Features of the CPI vision
• A National Resource– World-class, internationally recognised– Regional and UK Plc agenda– Scope - base, speciality, fine, pharmaceuticals, downstream
• Collaborative applied research and development– Market/Industry led – Incremental build of skills, knowledge, facilities and capability– Multi-company or one-on-one
• Manufacturers
• Catalyst producers
• Technology developers/suppliers
– Universities: regional, national and international
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So …..
• We’re here to reduce the barriers to innovation by – sharing risk, providing facilities, resources, and knowledge
• We’re a company limited by guarantee– we can’t make and distribute a profit
• We do not provide money……– We’re not a government grant agency
• We’re about action…we’re here to do things– With confidentiality assured
• We want a (small) share of the action – To cover costs and make us self-sustaining
• We recruit the Best Talent available– Work as a Team
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Strong Industry Involvement
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How CPI works
Industry/Market Demand
Functional Materials Advanced Processing &
ManufacturingThrusts
Platforms
Programmes
Science Base Universities
Supercritical Fluids
Company nCompany
Electronic Polymers
Collaborators
Demand
Technology Advisory Committee – oversees agenda and advises on relevance and quality
Academic links will be stimulated by part-sponsorship of chairs/post-docs/joint programmes
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Fuel Cell Applications Facility
• Objective: create a fuel cells cluster in the Tees Valley
• Static applications
– Supply security and fuel efficiency main drivers– Demonstrator projects
• Significant Involvement– DuPont, Huntsman, Johnson Matthey*, BOC, Air Products*, Terra Nitrogen,
Norsk Hydro, Black & Decker – Intelligent Energy*, Fuel Cells UK*, DTI, Carbon Trust, Canadian Research
Council, US Department of Energy
• Progress is substantial– 3 demonstrators in place, 2 more planned– Targeting €2.8bn European funding………enabling a supply chain
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Polymer Electronics
• Collaboration with DuPont Teijin Films– Initial project on the Functional Materials Platform– Objective is to develop luminescent polyester films for displays– “Disruptive Technology”– Development facility at CPI
• Progress– £xm project– DTF/CPI contract executed
• Potential consortium members– Xaar, Avecia, ICI, DuPont Teijin, Du Pont Displays, Kodak, Plastic
Logic, Cambridge Displays, Philips, University of Durham – UK Plastic Electronics Manufacturing Facility potential
………Building a new industry
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Functional Materials Platform
• Focused on developing new products – Significant number of opportunities– Challenge is not to get distracted!– Many companies interest in molecular level effects
but common agenda needs to be defined
• Advanced Functional Materials Centre Proposal– £xM application to DTI– £x+M matched by Industry– Links with University of Durham, White Rose Nano-factory and others
………Exploiting material properties
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Business Development
• Offers leading edge support and Technology Transfer to industry
– Facilitating improvement by sharing Best Practice– Pilot plant equipment brokerage– Specialist consultancy services– Direct support to 40+ SMEs
• Relationships with Universities– Possible sponsorship of chairs
• Newcastle for Chemical Engineering• Durham for Chemistry
– Encouraging collaborations between Universities – Interdisciplinary Research Centre in Polymer Science– Support to spin-outs and start-ups
………leveraging knowledge
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Bio-Processing
• Centre of Excellence in Bio-catalysis, Bio-transformations and Bio-catalytic Manufacturing – CoEBio3
– Focused on high value fine chemicals and pharmaceutical intermediates– Pro-Bio, EPSRC and DTI supported initiative– led by Prof Roberts from University of Manchester– £20m project over 5 years– Core academic research at Manchester plus York & Heriot-Watt– £2.5m capital pre-manufacturing scale up facility at CPI
• 20 + companies interested including:– AstraZeneca, GSK, Johnson Matthey, Angel Biotech, BASF– 15 already signed up as of 01/12/04
………developing new ways to make things
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Supercritical Fluids Processing
• A new processing route– Enables highly selective chemistry – Of interest to control particulate formulation– Novel process fluid e.g. water– Can be used to make a wide range of molecules
• Developing collaborative project with several companies, Nottingham University, Newcastle University and others
– Pre-competitive generic development – creating IPR for the partners– Initial programme focusing on water– £xm project– Future one-to-one programmes with other collaborators – catalysis,
hydrogenation
………developing new ways to make things
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Batch to Continuous Processing
• Significant opportunity:– Cost pressures as margins squeezed– Process & Analytical Technology (PAT) Initiative brings whole
pharmaceutical industry into play
• 4 consortia running or being established:– 5 companies working together with a university based
technology for novel reaction systems– Several companies coming together with CPI to look at heat-
exchange reaction systems– Bioreactor consortium is under development– A consortium is under development to look continuous
precipitation and crystallisation options
………developing new ways to make things
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Advanced Processing Platform
• Focused on manufacturing routes– More with less – increase capital intensity and variable cost efficiency– Increasing speed of development of new processes– Only making the molecules you want & reducing by-products– “Green” processing
• Vision is to systematically create a multi-purpose demonstration capability:
– 80:20 concept – non-optimised, proof of concept– Multiple feedstock and types– Reaction system options coupled with separation & purification
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Business Intensification by Advanced Processing
Feed
React
Separation+Product Handling
Water
SCF
Solvent
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Enzyme
Frisky
Slow, well mixed
Generic
e.g.Fermentor
e.g. Heat exchanger reactor
e.g OBR
CSTR
Business Intensification by Advanced Processing
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Business Intensification by Advanced Processing
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Speeding the adoption of new technologies
• Develop and demonstrate putative processes
• Produce trial quantities of product
• Demonstrate whole process
• Assess and mitigate commercial case and risk
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Thank You