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www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

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Page 1: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

The Centre for Process Innovation

Wilton, Redcar

Page 2: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

The Strategy for Success

Page 3: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Features of the CPI vision

• A National Resource– World-class, internationally recognised– Regional and UK Plc agenda– Scope - base, speciality, fine, pharmaceuticals, downstream

• Collaborative applied research and development– Market/Industry led – Incremental build of skills, knowledge, facilities and capability– Multi-company or one-on-one

• Manufacturers

• Catalyst producers

• Technology developers/suppliers

– Universities: regional, national and international

Page 4: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

So …..

• We’re here to reduce the barriers to innovation by – sharing risk, providing facilities, resources, and knowledge

• We’re a company limited by guarantee– we can’t make and distribute a profit

• We do not provide money……– We’re not a government grant agency

• We’re about action…we’re here to do things– With confidentiality assured

• We want a (small) share of the action – To cover costs and make us self-sustaining

• We recruit the Best Talent available– Work as a Team

Page 5: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Strong Industry Involvement

Page 6: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

How CPI works

Industry/Market Demand

Functional Materials Advanced Processing &

ManufacturingThrusts

Platforms

Programmes

Science Base Universities

Supercritical Fluids

Company nCompany

Electronic Polymers

Collaborators

Demand

Technology Advisory Committee – oversees agenda and advises on relevance and quality

Academic links will be stimulated by part-sponsorship of chairs/post-docs/joint programmes

Page 7: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Fuel Cell Applications Facility

• Objective: create a fuel cells cluster in the Tees Valley

• Static applications

– Supply security and fuel efficiency main drivers– Demonstrator projects

• Significant Involvement– DuPont, Huntsman, Johnson Matthey*, BOC, Air Products*, Terra Nitrogen,

Norsk Hydro, Black & Decker – Intelligent Energy*, Fuel Cells UK*, DTI, Carbon Trust, Canadian Research

Council, US Department of Energy

• Progress is substantial– 3 demonstrators in place, 2 more planned– Targeting €2.8bn European funding………enabling a supply chain

Page 8: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Polymer Electronics

• Collaboration with DuPont Teijin Films– Initial project on the Functional Materials Platform– Objective is to develop luminescent polyester films for displays– “Disruptive Technology”– Development facility at CPI

• Progress– £xm project– DTF/CPI contract executed

• Potential consortium members– Xaar, Avecia, ICI, DuPont Teijin, Du Pont Displays, Kodak, Plastic

Logic, Cambridge Displays, Philips, University of Durham – UK Plastic Electronics Manufacturing Facility potential

………Building a new industry

Page 9: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Functional Materials Platform

• Focused on developing new products – Significant number of opportunities– Challenge is not to get distracted!– Many companies interest in molecular level effects

but common agenda needs to be defined

• Advanced Functional Materials Centre Proposal– £xM application to DTI– £x+M matched by Industry– Links with University of Durham, White Rose Nano-factory and others

………Exploiting material properties

Page 10: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Business Development

• Offers leading edge support and Technology Transfer to industry

– Facilitating improvement by sharing Best Practice– Pilot plant equipment brokerage– Specialist consultancy services– Direct support to 40+ SMEs

• Relationships with Universities– Possible sponsorship of chairs

• Newcastle for Chemical Engineering• Durham for Chemistry

– Encouraging collaborations between Universities – Interdisciplinary Research Centre in Polymer Science– Support to spin-outs and start-ups

………leveraging knowledge

Page 11: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Bio-Processing

• Centre of Excellence in Bio-catalysis, Bio-transformations and Bio-catalytic Manufacturing – CoEBio3

– Focused on high value fine chemicals and pharmaceutical intermediates– Pro-Bio, EPSRC and DTI supported initiative– led by Prof Roberts from University of Manchester– £20m project over 5 years– Core academic research at Manchester plus York & Heriot-Watt– £2.5m capital pre-manufacturing scale up facility at CPI

• 20 + companies interested including:– AstraZeneca, GSK, Johnson Matthey, Angel Biotech, BASF– 15 already signed up as of 01/12/04

………developing new ways to make things

Page 12: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Supercritical Fluids Processing

• A new processing route– Enables highly selective chemistry – Of interest to control particulate formulation– Novel process fluid e.g. water– Can be used to make a wide range of molecules

• Developing collaborative project with several companies, Nottingham University, Newcastle University and others

– Pre-competitive generic development – creating IPR for the partners– Initial programme focusing on water– £xm project– Future one-to-one programmes with other collaborators – catalysis,

hydrogenation

………developing new ways to make things

Page 13: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Batch to Continuous Processing

• Significant opportunity:– Cost pressures as margins squeezed– Process & Analytical Technology (PAT) Initiative brings whole

pharmaceutical industry into play

• 4 consortia running or being established:– 5 companies working together with a university based

technology for novel reaction systems– Several companies coming together with CPI to look at heat-

exchange reaction systems– Bioreactor consortium is under development– A consortium is under development to look continuous

precipitation and crystallisation options

………developing new ways to make things

Page 14: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Advanced Processing Platform

• Focused on manufacturing routes– More with less – increase capital intensity and variable cost efficiency– Increasing speed of development of new processes– Only making the molecules you want & reducing by-products– “Green” processing

• Vision is to systematically create a multi-purpose demonstration capability:

– 80:20 concept – non-optimised, proof of concept– Multiple feedstock and types– Reaction system options coupled with separation & purification

Page 15: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Business Intensification by Advanced Processing

Feed

React

Separation+Product Handling

Water

SCF

Solvent

Page 16: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Enzyme

Frisky

Slow, well mixed

Generic

e.g.Fermentor

e.g. Heat exchanger reactor

e.g OBR

CSTR

Business Intensification by Advanced Processing

Page 17: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

D

A---->B---->C---->D

A

B

B2C

Business Intensification by Advanced Processing

Page 18: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Speeding the adoption of new technologies

• Develop and demonstrate putative processes

• Produce trial quantities of product

• Demonstrate whole process

• Assess and mitigate commercial case and risk

Page 19: Www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd The Centre for Process Innovation Wilton, Redcar

www.uk-cpi.com © & Confidential to The Centre for Process Innovation Ltd

Thank You