YSF- FEBS Working Group on the Career of Young Scientists

Claudina Rodrigues-Pousada

Activities of the YSF at the 22nd IUBMB/37th FEBS2012, Seville

FROM SINGLE MOLECULES TO SYSTEM BIOLOGY

The organization of the scientific program of the 12th YSF, 2012 was completed according to the program included as an annex of this report (annex1). The YSF was held in the seaside resort of Costa Ballena (Cádiz), in sunny Spain, 1-4 September 2012. The site was indeed nice but unfortunately quite expensive that among other matters made the budget to exceed largely 1,000 per student. The budget is shown in annex 2 in which can be seen that the total sum is 136,000 Euros. A comparison with the budget of the 11th YSF with the one of this year is presented. I have identified a few problems that can explain this discrepancy. For instance the organizers have taken as reference the budget of the 10th YSF meeting held in Gothenburg which presented an excess of 13,000 Euros. However this divided by 125 students gives 1,109.24 Euros per student e.g. 11% increase in Gothenburg and now we are spending 1 360.€ per student that means 36% increase! Another problem is related to the fact that the chairman of the Organizing committee of the 12th YSF of Seville did not attend the 11th YSF in Torino and as such they could not be well informed about all the process. The lack of communication was also a problem as the OC worked independently without asking the correct information.

The Organizing Committee (OC) was composed of Irene Díaz-Moreno (the chairman) and Ricardo Louro (Vice-chairman) and José Manuel García-Heredia besides 6 students to help them. Many thanks are due to all of them for their efforts in arranging with efficiency this event.

I will give a detailed oral report on the YSF meeting at the council with more relevant information on the way how the forum developed. As you can see in annex 3, 36 countries were represented, but we did not have applicants from Norway. The total number of applicants was 490 from which 100 were selected (Figure 1), and the average age was between 26 and 28 years old. Another aspect which should be emphasized is that the number of female applicants is like in the previous year’s higher (67%) than the number of male applicants (33%). We equilibrated however this ratio after selection (45% M and 55% F).

I prepared a questionnaires addressed to the students with FEBS grants whose answers will be analysed and I will show to the council.

13th YSF in St Petersburg

With respect of the 13th YSF to be held in St Petersburg next year the chairman is Alexey Belogurov who is in contact with me addressing all the pertinent questions and I am also sending all the information as to avoid all the problems which we have had this year mainly the one related to the budget. I could appreciate his way of working because he came to Seville and has collaborated in the selection of our students. It was really quite helpful his contribution in this task.

Annex 1

Programme

Welcome & Opening (19:30-20:00)

· Irene Díaz-Moreno (Chair of YSP2012) · Angelo Azzi (IUBMB President) · Claudina Rodrigues-Pousada (Chair of the FEBS Working Group on the Career of Young Scientist) · Mike Walsh (General Secretary of IUBMB)

· Vicente Rubio (Chair of FEBS Fellowships) · Ricardo Louro (co-Chair of YSP2012) ______________________________________________________________________

Oral Session 1: PROTEIN STRUCTURE AND DYNAMICS (8:30-9:30) · Cheng-Chung Lee (Taiwan): The Hexameric Structures of Human Heat Shock Protein 90 - 12 +3 min · Ana Sofia Fernandes Oliveira (Portugal): Molecular mechanisms of ABC transporters: Insights from Molecular Dynamics simulations - 12 +3 min · Feng Wang (USA): T Cell Receptor and Membrane Dynamics Analyzed with Super-Resolution Imaging Secondary Ion Mass Spectrometry - 12 +3 min · Markus Weingarth (The Netherlands): Unravelling supramolecular organisation of membrane proteins by solid state NMR and Molecular Dynamics simulations - 12 +3 min ______________________________________________________________________

GUEST-PRESENTATION Dan Tawfik _______________________________________________________________________

Oral Session 2: PROTEIN FUNCTION (11:00-12:00)

· Jonathan Bizarro (France): Deciphering the role of Trip3 and the R2TP in the assembly of RNP complexes containing L7Ae protein - 12 +3 min · Alison Parkin (United Kingdom): Hydrogenases: highly active and selective biological H2 catalysts to inspire Pt-free H2/O2 fuel cells - 12 +3 min · Joana Alexandra Teixeira Rosa (Portugal): Identification of novel molecular determinants of tissue mineralization in fish - 12 +3 min · Agnes Toth-Petroczy (Israel): Why do some proteins evolve slowly? - 12 +3 min

Oral Session 3: SINGLE MOLECULES AND SYSTEMS BIOLOGY (16:30-17:30) · Louise Aigrain (United Kingdom): Single-molecule fluorescence in bacteria cells - 12 + 3 min · Isabel Cruz Gallardo (Spain): Structural screening of cupredoxins against malaria - 12 + 3 min · Meenakshisundaram Kandhavelu (Finland): Probing the in vivo transcription initiation dynamics of unidirectional promoters at the single molecule level - 12 + 3 min · Adi Minis (Israel): New insights gained from neuronal sub-cellular transcriptomics by deep sequencing - 12 + 3 min

____________________________________________________________________ Oral Session 4: SIGNALING (17:30-18:45) · Lisa Arzt (Austria): What is the reason for the deregulation of the STAT signaling pathway in malignant pelural mesotheolioma? - 12 + 3 min · Gavin Higgins (Australia): Relationship between autophagy and ubiquitin-proteasome system during neuronal cell death under oxidative stress - 12 + 3 min · Diego Rojas Rivera (Chile): TMBIM3/GRINA is a novel unfolded protein response (UPR) target gene that controls apoptosis through the modulation of ER calcium homeostasis - 12 + 3 min · Lukasz Dariusz Skalniak (Poland): MCPIP1, regulating the regulator - 12 + 3 min · Tobias Wagner (Germany): Deacetylation of p53 and apoptosis following genotoxic stress are regulated by sumoylation of HDAC2 - 12 + 3 min

_____________________________________________________________________ GUEST-PRESENTATION – EMBO Young Investigator lecture

Ben Lehner - The Biology of individuals

__________________________________________________________________________ Oral Session 5: GENE REGULATION (8:30-9:30)

· Artem Bonchuk (Russia): Multimerization domains of insulator proteins of Drosophila melanogaster in long-range genomic interactions - 12 + 3 min · Sarah Diermeier (Germany): Epigenomic Characterization of the Structure-Function Relation in Chromatin - 12 + 3 min · Sarah Louise Dombernowsky (Denmark): Molecular mechanisms of Adam17 activation - new directions from a functional genomic screen - 12 + 3 min · Sebastian Przemyslaw Sacharowski (Poland): Analysis of expression and identification of interacting partners of ATSWP73A and ATSWP73B subunits of Arabidopsis SWI/SNF-type chromatin remodeling complex - 12 + 3 min

______________________________________________________________________

GUEST-PRESENTATION Ángela Nieto : Twenty years with a snail

_______________________________________________________________________ Oral Session 6: DISEASES (11:00-12:00) · Benedetta Mannini (Italy): Chaperones suppress the toxicity of aberrant protein aggregates. Molecular insight into the mechanism of action - 12 + 3 min · Laura Nogués-Vera (Spain): G Protein coupled Receptor Kinase 2 (GRK2) contributes to cellular transformation and breast tumor progression - 12 + 3 min · Aida Platero Luengo (Spain): Vascular niche factors regulate rodent adult carotid body stem cell activity - 12 + 3 min · Maria Ryazantseva (Russia): Mutations in presenilin-1 gene linked with Alzheimer's disease cease impairments in calcium channels functions in neurons - 12 + 3 min

_________________________________________________________________________

ROUND-TABLE

Development of Scientific Career Talks (16:30- 19:15) Young Scientist Career (16:30-17:00) · Claudina Rodrigues-Pousada (Chair of the FEBS Working Group on the Career of Young Scientists): How FEBS is promoting the young scientist career - 12 +3 min · Mike Walsh (General Secretary of IUBMB): Travels of an academic biochemist - 12 +3 min Journals (17:00-18:00)

· Angelo Azzi (President of IUBMB): Writing, submitting and publishing a scientific paper - 35 min + 5 min · Pura Muñoz Cánoves (FEBS Journal Editor): FEBS Journal - 15 + 5 min Fellowships (18:00-18:45) · Alan Craig (European Research Council): Marie Curie Fellowships - European Funding for Researchers - 12 + 3 min

· Andrea Hutterer (European Molecular Biology Organisation): EMBO and the EMBO Fellowship Programme - 12 + 3 min · Vicente Rubio (Chair of the FEBS Fellowships Committee): The scope of FEBS Fellowships - 12 + 3 min

Entrepreneurs (18:45-19:00)

Stuart Levy: Can an academic be an entrepreneur? - 12 + 3 min CV Workshop (19:00-19:15) · Keith Elliot (FEBS Biochemical Education): Preparing your curriculum vitae. How to make the most of yourself! - European Funding for Researchers - 12 + 3 min

Annex 2

Budget and comparison with the one of 11th YSF held in Torino, Italy

Slides Figure 3

YSF- FEBS Working Group on the Career of Young Scientists

YSP/12th YSF-2012, September 1st -4th 2012, Seville/Costa Ballena

Chairman: Claudina Rodrigues-Pousada

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Working Group During my visit to Seville to select the participants27th – 29th February

Alexey Irene Ricardo JoséJordi Alexey

Belegurov is the chairman of the 13th YSF

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80%

20% PhD students

Post-doc

83%

17%Total Number of FEBS participants ....490Selected............................................. 100 <> 20.4%Total Number of IUBMB..................... 108Selected.............................................. 20 <> 18.5%

Budget: FEBS 136,000 €IUBMB 40,000 €

Some Figures

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Before selection

After selection

Females

Males

45% 55%

33%

67%

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Distribution of the selected participants according to the age

AGE

Participants

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Distribution by Countries

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13th YSF In S Petersburg in 2013Alexey Belegurov is the chairman of the 13th YSF

ABOUT

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