STARHOTELS ROSA GRANd

piazza Fontana 3, milano

6TH INTERNATIONAL CONFERENCE ON THORACIC ONCOLOGY

Milan, June 21st - 23rd 2018

programmE

AIOT Board

Fortunato CiardielloFilippo de MarinisCesare GridelliLucio Crinò

Marina Chiara GarassinoNicola Normanno Lorenzo Spaggiari

Filippo de Marinis

SCIENTIFIC & ORGANIZING COMMITTEE

PRESIDENT OF THE CONFERENCE

WELCOME FROM THE PRESIDENTUnder the auspices of

Dear Collegue,

it’s my great pleasure to invite you to partecipate in theproceedings of 6th

Italian Conference on Thoracic

Oncology (CIOT) that, in its annual recurrence, will takeplace in Milan from June 21st to June 23rd 2018organized by AIOT (Italian Association of ThoracicOncology) and that I’ve the responsibility to chair.

I would like to call your attention to at least threeinteresting aspects of Milan’s Conference that make theappointment very peculiar and that I identify in itsInternational form, in the location and in its goals.

International form

The 70% of Faculty is composed of foreignspeakers, everybody playing an active part in clinicalresearch in Thoracic Oncology and KOL in theirrespective countries. We expect a significant foreigndelegation. The official language of the Conference willbe English.

Location

Located in a wonderful position, in the heart ofMilan, the conference venue offers to the city a meetingpoint of extraordinary importance. Its natural eleganceand flexibility make it the ideal location for congresses,meetings and events of any kind.The location is in the heart of history and Milan fashiondistrict.

Goals

Setted immediately after ASCO, the Conferencewill give an update on the data coming from ClinicalResearch in Thoracic Oncology directly from the voiceof its Authors more representative in an appointmentthat we would like to be lasting inside of the internationalcongressional track.

For these reasons I’m trusting that you shouldappreciate the effort of the organizing secretariat torealize this scientific meeting doing credit to us withyour attendance in Milan.

Arrivederci

President of 6th CIOTFilippo de Marinis

CONFERENCE VENUE

STARHOTELS ROSA GRAND piazza Fontana 3, milano

Tel. (+39) 02 88311

The STARHOTELS ROSA GRAND is located in thecenter of the main cultural area of the city and about500 metres from the famous shopping area.The meeting takes place in the Auditorium located atthe ground floor of the Hotel.

HOTEL ACCOMMODATIONOrganizing secretariat SOS Scientific OrganizingService S.r.l. (rossella.spinetti@alice.it), will be at yourdisposal for any information on hotel reservations.

GENERAL INFORMATION

PARKING FACILITIESThe indoor car parking, located aside the Hotel, will beat disposal of all the delegates at their charge;

SECRETARIAT AND REGISTRATION DESKSThe pre-registration and on site registration desks willbe at the disposal of participants as follow:

Thursday, June 21 - 13.00/18.30 hrsFriday, June 22 - 09.00/18.30 hrs

Saturday, June 23 - 09.00/13.00 hrs

At the secretariat desk will be available the followingservices:• On site registration (cash, cheques)• Pre-registrations A - L• Pre-registrations M - Z• Faculty registration • CME credits desk

CLOAKROOMIt will be at disposal of all the guests free of charge.Delegates are kindly requested not to leave theirpersonal belongings after the closing time.

BARLocated in the Conference area it will be at thedisposal of the participants at their charge.

INSURANCEConference organizers cannot accept liability forpersonal injuries or for loss of or damage to propertybelonging to congress participants, either during or asa result of the Conference.

CLIMATEJune weather in Milan is generally sunny and warm.The temperature often rises during the day at anaverage of 25°. Light summer clothing is mostsuitable. Rain is also possible; light raincoat andsomething warm for the evening are advisable

CURRENCYThe official currency in Italy is the Euro (€).

TIPPINGService is usually included in the bill in bars andrestaurants but tips are welcome.

BANKBanks are open from Monday to Friday from 08.30 to13.30 hrs and from 15.00 to 16.00 hrs. Banks areclosed on Saturday and Sunday. Many banks haveautomatic currency exchange machines that also takecredit cards.Most hotels, restaurants and shops accept foreigncurrency and major credit cards.

ELECTRICITYVoltage is 220V AC, 50Hz. Plugs have two or threeround pins. Foreign voltage could require and adapter.

PRACTICAL INFORMATION

All fees are requested in Euros.It’s possible to register individually by visiting AIOTwebsite www.oncologiatoracica.it in the propersection following the instructions.

WHAT IS COVERED BY THE FEE?The registration fee includes an unlimited access to allscientific sessions, a full set of congress material andlunch on Friday June 22.

ADMISSIONName badges will be used as passes. All participantsand official guests are kindly requested to wear theirname badge during the Meeting activities and socialevents. The badge will allow the entrance to thescientific sessions and lunch.

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REGISTRATION FEES

KEY ATTRACTIONS

MILAN

MILAN KEY ATTRACTIONS

11. Duomo 4. Santa Maria delle Grazie

2. Palazzo Reale 5. Navigli

3. Castello Sforzesco 6. Via Monte Napoleone

7. Piazza Gae Aulenti

8. Citylife

3

12

4

5

6

7

8

SCIENTIFIC INFORMATION

MAIN SCIENTIFIC PROGRAMME OUTLINEThe scientific programme covers three days (ThursdayJune 21, Friday June 22 and Saturday June 23, 2018)and consists of State-of-the-Art Lectures, MainLectures, Debates and Face to Face sessions.

The “Debates” sessions will be about controversialtopics in thoracic oncology; the “Face to Face”sessions instead will go on vexed questions and theywill deal with two speakers and to add requests fromsome “shooters” put in charge in order to stimulatethe audience for a lively discussion.

WEBSITEVirtual Meeting of the Conference will be availableafter the end of the Meeting on AIOT official websitewww.oncologiatoracica.it.

ITALIAN MINISTRY OF HEALTH - CME CREDITS The accreditation has been asked for entirely meeting.To obtain Italian credits the delegates must attend inthe 100% percentage of the time sessions. Anelectronic device will be arrange.

At the moment of registration each participant will receivethe evaluation forms and learning questionnaire of thescientific sessions. These forms and questionnairemust be filled in and return to the “CME credits” desk. Electronic tags will be used to record the CME credits.

The electronic readers will be placed just outside the“Auditorium”. It will be sufficient to pass through theelectronic device to have the credits recorded.

To obtain credits, Italian participants must be:

• record both the entrance and the exit of eachMeeting day

• return the electronic tag to the Organizing Secretariatat the end of the Conference

• return the evaluation forms and questionnaire dulyfilled into the “CME credits” desk. The anagraphicaldata must compulsorily be indicated since requiredby the Italian Ministry of Health

Please note that should you loose or fail the tag,you will be charged € 10,00 by the OrganizingSecretariat.

FACULTYGuidelines for Speakers and Chairs

For Chairs:• Locate your session Room in due time

• Be in the Room assigned for presentation at least 10minutes before the beginning of the session

• Respect the timing allowed to the session and eachpresentation

• All presentations, discussions and questions are inEnglish

For Speakers:• Follow the instructions indicated at the paragraph“Audiovisual Instructions”

• Locate your session Room in due time

• Be in the Room assigned for presentation at least 10minutes before the beginning of the session to meetthe Chairs

• Respect the timing allowed for your presentation

• All presentations, discussions and questions are inEnglish

AUDIOVISUAL INSTRUCTIONSA multimedial projection centre will be at the disposalof the Speakers at the ground floor of the StarhotelsRosa Grand aside the Auditorium.

ONLY PC DATA PROJECTION WILL BE AVAILABLE AT THE CONFERENCE

The “Auditorium” will be provided with the laptop.Use of one’s laptop is not allowed.

Should Speakers have their personal laptop, a CDRom or a USB key, they are kindly requested to go tothe multimedial projection centre to have theirpresentation copied. The presentation will be thenforwarded through a LAN network from multimedialprojection centre directly to the computer in thepresentation room.

We recommend to contact the multimedial projectioncentre the day before your presentation. At any rate,presentation material must be available:

• 45 minutes before for Power Point presentation onCD Rom or USB key

• 1 hour before for presentation on Personal Computer

CERTIFICATE OF ATTENDANCEAttendance certificates will be issued on request to allregularly registered participants at the SecretariatDesk at the end of the meeting.

FACULTY GUIDELINES

June 21st, 2018 THURSDAY

WELCOME LECTURE FROM THE PRESIDENT OF IALSC

14.30 Introduction: Fortunato Ciardiello (Naples, I)

14.35 Lecture Giorgio Vittorio Scagliotti (Turin, I)

FACE TO FACE ITREATMENT OF OLIGOMETASTATIC NSCLC:SURGERY VS RADIOTHERAPY AFTER SYSTEMIC TREATMENT

Chair: Lucio Crinò (Meldola, I)

15.00 Pro surgery Lorenzo Spaggiari (Milan, I)

15.20 Pro radiotherapy Cecile Le Pechoux (Paris, F)

15.40 Discussion

PROGRAMME

16.00-17.00 SCIENTIFIC SESSIONLOCALLY ADVANCED NSCLC: FROM BENCH TO BESIDE

Unrestricted grant

Modera: Filippo de Marinis (Milan, I)

Intervengono:. il radioterapista Umberto Ricardi (Turin, I). l’oncologo Marina Chiara Garassino (Milan, I)

FACE TO FACE IIANTIANGIOGENETICS IN A-NSQ NSCLC THERAPY: 1ST VS 2ND LINE USE

Chair: Fortunato Ciardiello (Naples, I)

17.00 Pro first-line Javier De Castro (Madrid, E)

17.20 Pro second-line Maurice Perol (Lion, F)

17.40 Discussion

LECTURE IINEW OPTIONS IN SCLC TREATMENT

18.00 Introduction: Cesare Gridelli (Avellino, I)

18.10 Speaker:Naiyer Rizvi (New York, US)

June 22nd, 2018 FRIDAY

09.00-10.00 SCIENTIFIC SESSIONSELEZIONE E SEQUENZA DI TRATTAMENTO: HOT TOPICS NEL NSCLC

Unrestricted grant

Modera: Filippo de Marinis (Milan, I)

Intervengono. il patologo Massimo Barberis (Milan, I). l’oncologo Federico Cappuzzo (Ravenna, I)

SPECIAL SYMPOSIUM ITHE BEST TREATMENT SEQUENCE OF NSCLC WITH ALK GENETIC ALTERATION

Chair: Marina Chiara Garassino (Milan, I)

10.00 Starting from Crizotinib Benjamin Besse (Paris, F)

10.20 Starting from Alectinib Tony Mok (Hong Kong, HKG)

10.40 New options after biological 1st line failure Enriqueta Felip (Barcelona, E)

11.00 Discussion

ARENA2ND LINE NSCLC IMMUNOTHERAPY AMONG DIFFERENT MABS

Chair: Cesare Gridelli (Avellino, I)

11.20 Nivolumab Suresh Ramalingam (Atlanta, US)

11.40 Pembrolizumab Naiyer Rizvi (New York, US)

12.00 AtezolizumabDavid Gandara (Sacramento, US)

12.20 Discussion

LECTURE IIIIS THE BRAIN STILL A SANCTUARY OR A NEW TARGET IN LUNGCANCER TREATMENT?

18.00 Introduction: Federico Cappuzzo (Ravenna, I)

18.10 Speaker:Tony Mok (Hong Kong, HKG)

15.00-16.00 SCIENTIFIC SESSIONPROSPETTIVE FUTURE NEL NSCLC: COME CAMBIA LO SCENARIOE PERCHÈ?

Urestricted grant

15.00 Status quo sulle terapie di combinazioneMarina Chiara Garassino (Milan, I)

15.20 Quale lo scenario futuro: come cambia e perchèFilippo de Marinis (Milan, I)

15.40 Discussione

16.00-17.30 SCIENTIFIC SESSION

LE LINEE GUIDA DEL NSCLC

Unrestricted grant

16.00 Introduzione:Cesare Gridelli (Avellino)

16.20 NSCLC non oncogene addicted: il ruolo dell’immunoterapiaFilippo de Marinis (Milan, I)

16.40 NSCLC oncogene addicted: il ruolo dei TKIs di seconda/terza generazioneFederico Cappuzzo (Ravenna, I)

17.00 Il ruolo della “Patient Advocacy” nella decisione terapeuticaMarina Chiara Garassino (Milan)

17.20 Linee Guida AIOTCesare Gridelli (Avellino, I)

Al termine della sessione verranno distribuite le Linee Guida AIOT aggiornate al 2018

June 23rd, 2018 SATURDAY

SPECIAL SYMPOSIUM III1ST LINE A-NSCLC IMMUNOTHERAPY: SINGLE AGENT OR COMBO

Chair: Lucio Crinò (Meldola, I)

09.00 Predictive biomarkers for immunotherapy Keith Kerr (Aberdeen, US)

09.20 PD-1 MAbs Martin Reck (Groshansdorf, D)

09.40 PD-L1 MAbs Shirish Gadgeel (Detroit, US)

10.00 Discussion

FACE TO FACE IIITHE BEST TREATMENT SEQUENCE OF NSCLC WITH EGFR MUT+

Chair: Filippo de Marinis (Milan, I)

10.20 Starting with Osimertinib Suresh Ramalingam (Atlanta, US)

10.40 Starting from 1st/2ndgeneration TKIs Luis Paz Ares (Madrid, E)

11.00 Discussion

SPECIAL SYMPOSIUM IVNEW TARGETS: WHERE ARE WE?

Chair: Nicola Normanno (Naples, I)

11.20 ROS-1 Federico Cappuzzo (Ravenna, I)

11.40 B-RAF David Planchard (Paris, F)

12.00 c-MET Christian Rolfo (Antwerp, B)

12.20 Discussion

CLOSING LECTURE IVNEW OPTIONS IN MPM SYSTEMIC TREATMENT

12.40 Introduction Filippo de Marinis (Milan, I)

12.45 Speaker: Shirish Gadgeel (Detroit, US)

13.15 Closing of the conference Fortunato Ciardiello e Filippo de Marinis

LEVEL SPONSOR

OTHER SPONSOR

BRONZE SPONSOR

PLATINUM SPONSOR

GOLD SPONSOR

SCIENTIFIC SECRETARIATAIOT - Associazione Italiana di Oncologia Toracica

Via Salaria, 237 - 00199 RomaTel. +(39) 333 65 93 541 - Fax (+39) 06 85 40 679

oncologiatoracica@yahoo.it - www.oncologiatoracica.it

ORGANIZING SECRETARIAT bySOS S.r.l.

Via Salaria, 237 - 00199 Roma Tel. (+39) 333 65 93 541 - Fax (+39) 06 85 40 679

www.scientificorganizingservice.com - rossella.spinetti@alice.it

THIS PROGRAMME AND REGISTRATION FORM ARE AVAILABLE ON AIOT WEBSITE

www.oncologiatoracica.it