a700 iviivviv -test slide, various normal tissuesiv).pdf · a700(iv): test slide, various normal...

For research use only

A700IVIVIVIV-Test slide, Various normal tissues

(formalin fixed)

Specifications:

• No. of cases: 12

• Tissue type: Test slide, Various normal tissues

• No. of spots: 12 non-neoplastic spots (12 spots)

•Total spots: 12

• Corresponding normal tissues with cancers:

• Diameter: 1. 0 mm

Documents:

• Product specification: layout, summary of tissue spots

• H&E stained images

• Detailed pathological information

Layout:

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Summary of tissue spotsFor research use only(formalin fixed)

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QC sheet_LOT#112111005021

Hematoxylin and Eosin staining

For research use only(formalin fixed)

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A1 A2 A3 A4

A5 A6 B1 B2

B3 B4 B5 B6

NoNoNoNo SexSexSexSex AgeAgeAgeAge Key wordKey wordKey wordKey word Histological DiagnosisHistological DiagnosisHistological DiagnosisHistological Diagnosis

1111 A 1 m 53Liver:

non-neoplastic

Liver, segmentectomy: Hepatocellular carcinoma 1) size: 4.5cm in the greatest dimension 2) Edmondson grade I to II 3) trabecular and compact histologic type 4) infiltrative growth pattern with intrahepatic metastasis 5) hepatic capsular invasion 6) no vascular invasion 7) intact intrahepatic resection margins (safety margin: less than 2mm) 8) extensive necrosis(more than 85% of total volume) 9) non-neoplastic liver showing chronic B viral hepatitis with moderate inflammatory activity(Grade III) macronodular cirrhosis (Stage IV) and fatty metamorphosis(grade II:25-50%)Gallbladder, cholecystectomy, separately submitted: Chronic cholecystitis with cholesterol polyp.

2222 A 2 f 74Lung:

non-neoplastic

Lung, left lower lobe, lobectomy: 1. Left lower lobe: Non-small cell carcinoma, mainly large cell carcinoma, with focal area of clear cell carcinoma and acinar type adenocarcinoma. - mass size: 5.5x5cm - visceral pleural involvement - marked tumor necrosis 2. Surrounding lung - Obstructive pneumonitis - Honey-comb lung, focally - Bronchiectasis and emphysema 3. Bronchial resection margin: Free of tumor. 4. Regional lymph node: Free of tumor in all nodes(0/21), in detail, A-P window(0/5), left lower paratracheal(0/1),IPL(0/4), subcarinal(0/4), hilar(0/2), peribronchial(0/5). 5. Results of special staining:Mucicarmine(-), PAS(+), S-100(-), Synaptophysin(-), NSE(-), Chromogranin(-).

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A700(IV): Test slide, Various normal tissues

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NoNoNoNo SexSexSexSex AgeAgeAgeAge Key wordKey wordKey wordKey word Histological DiagnosisHistological DiagnosisHistological DiagnosisHistological DiagnosisCoordinateCoordinateCoordinateCoordinate


3333 A 3 m 69stomach:

non-neoplastic

Stomach, subtotal gastrectomy: Ulceroinfiltrative adenocarcinoma(Borrmann type III), poorly differentiated, with multifocal retrodifferentiation, in antrum 1) size: 8x7cm 2) infiltrative growth type(Ming classification) and gastric type(Japanese classification) 3) extension to perigastric soft tissue and serosa 4) marked hemorrhagic necrosis 5) no venous invasion 6) non neoplastic stomach showing multifocal atrophic gastritis Resection margins, proximal and distal: Free of tumor. Lymph nodes, No.3(1/7), No.7(0/12), No.8(0/2), No.12(0/1):(1/22): Tumor metastasis to 1 out of 22 lymph nodes with perinodal soft tissue extension.

4444 A 4 f 66colon:

non-neoplastic

Sigmoid colon with pericolic fatty tissue, low anterior resection: Fungating adenocarcinoma, well to moderately differentiated, probably arising in adenomatous polyp 1) size: 8.5x5.5x3.2cm 2) infiltrative growth 3) extension and metastasis to pericolic soft tissue 4) vascular invasion 5) intact proximal and distal resection margins 6) metastasis to 5 out of 15 pericolic regional lymph nodes (pericolic(5/15) and principal, separately submitted(0/0))

5555 A 5 m 52brain:

non-neoplastic

autopsy

6666 A 6 m 52heart:

non-neoplastic

autopsy

7777 B 1 f 74kidney:

non-neoplastic

Kidney, right, nephrectomy: Angiomyolipoma, focally extending beyond renal capsule, but confined to Gerota's fascia. Ureter, resection margin: Free of tumor. Renal artery and vein: Free of tumor. Adrenal gland: Free of tumor. Result of immunohistochemistry: Vimentin(+), Actin(+), Desmin(+), Low MW Cytokeratin(-), EMA(-), Factor VIII(-), CD31(-), S-100(-).

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NoNoNoNo SexSexSexSex AgeAgeAgeAge Key wordKey wordKey wordKey word Histological DiagnosisHistological DiagnosisHistological DiagnosisHistological DiagnosisCoordinateCoordinateCoordinateCoordinate


8888 B 2 f 46breast:

non-neoplastic

Breast, right, mastectomy: 1. Fibrocystic change with foci of adenosis, columnar cell change and papillomatosis. 2. No residual ductal carcinoma in situ. 3. Nipple and areoila: Free of tumor. 4. Overlying skin: Free of tumor. 5. Underlying fascia: Free of tumor. 6. Regional lymph node, axillary(0/8): Free of tumor.

9999 B 3 f 41fallopian tube:non-neoplastic

Ovary and fallopian tube, side unstated, salpingooophorectomy: 1. Ovary: Borderline serous and mucinous tumor with serous micropapillary pattern (so called micropapillary serous adenocarcinoma by Kurman), confined within ovarian capsule. 2. Fallopian tube: No pathological diagnosis.

10101010 B 4 f 46pancreas:

non-neoplastic

Pancreas, distal pancreatectomy: Serous oligocystic adenoma.

11111111 B 5 f 8spleen:

non-neoplastic

Pancreas, distal pancreatectomy: Thin walled unilocular cyst lined by acellular collagenous tissue and surrounding dysgenetic duct structures, highly suggestive of congenital(dysgenetic) cyst, see note.Spleen, splenectomy: No pathological diagnosis.Appendix, appendectomy: No pathological diagnosis.

12121212 B 6 f 67skin: non-neoplastic

Skin, vulva, left, excision: Polypoid proliferation of collagen fibers associated with blood vessels, most likely fibroepithelial polyp(skintag).

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