adeeva life care presentation

Wishing you for a betterment…

WELCOMETO

ADEEVA LIFECARE PVT. LTD.

Adeeva Life Care Pvt. Ltd. is setup by KPS Clinical Services Pvt. Ltd. (a

leading Contract Research Organization) in the auspicious of RAHE

Group of Organizations.

Adeeva Life Care is a different kind of pharmaceutical and healthcare

products company. We are an India based company focused on

management of various kinds of ailments by developing our unique

range of innovative products.

VISION

To become a top leading brand as pharmaceutical & healthcare

company across the globe in sphere of excellence by providing

innovative, therapeutically effective and economical

pharmaceutical and rehabilitation products for the better health

of human race.

MISSION

•To serve and redress the sufferings of human race and march

ahead in making world free from ailments.

•To win the trust of customers by catering them high quality

products.

•To provide the healthcare products at economical price.

•To comply with the highest regulatory standards.

•Manage to provide uninterrupted services to our business allies.

SERVICES AT A GLANCE

ADNOSYL

ADNOXIB-90

ADLORPHEN

ADEGOPAIN

ADLAZINE-L

PRODUCT CATEGORIESPHARMACEUTICALS

ADLAZINE-L KID

BAINPRAM

CLAVUGONO

OCLOPEP

DANENTIA-AD


VATIORTH

WISONAD

CLACUCAL

ADNOSYL-WIN


Composition

Ferrous Ascorbate 100 mg

Folic Acid IP 1.5 mg

Adenosylcobalamin 15 mcg

Zinc sulphate 22.5 mg

IndicationsFor pregnant women to:•To prevent spina bifida in an unborn fetus, • To improve iron utilization•To prevent folate or iron deficiency anemia

Mechanism of Action

Ferrous Ascorbate is a synthetic form of iron and vitamin C. It converts the ferric form to ferrous form, making it absorbable from duodenum & upper jejunum, thus enhancing the absorption of iron.Folate is necessary for production & maintenance of new cells, for DNA synthesis and RNA synthesis, important during frequent cell division and growth, such as infancy and pregnancy.Adenosylcobalamin, (Vitamin B12 supplement,) used in treatment & prevention of Vitamin B deficiency, depression, panic attacks and anxiety.It is also used as nutritional supplement to promote anabolism, increase muscle strength & mass, improve mental concentration in adults.

Dosage One tablet OD

ADNOSYL

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ADNOXIB-90

Composition: Etoricoxib-90 mg

Mechanism of Action

Etoricoxib is a member of a new class of agents called coxibs.

It is a potent, orally active cyclooxygenase2 (COX-2) specific inhibitor..

Selective inhibition of COX-2 ↓ses pain, inflammation, these symptoms with decreased potential for GI toxicity and effects on platelet aggregation

IndicationsTo treat painful conditions such as :

Arthritis, Gout and dental pain after surgery.

It eases pain and reduces inflammation

ADNOXIB-90Dosage: 90mg OD - For rheumatoid arthritis or ankylosing spondylitis . After dental surgery up to three days .120 mg OD - For Gout

COMPETITORS

BRAND NAME COMPANY NAME

ALCOXIB ALKEM

ALCOX ALTAR LS

EBOV GLENMARK

BIOTROX BIOCHEMIX

ECOXPIC-P ALPIC BIOTECH

ADEGOPAIN

Composition

Thiocolchicoside 4mg

Aceclofenac 100mg

Mechanism of Action

Aceclofenac

M.O.A based on inhibition of prostaglandin synthesis.

Inhibitor of enzyme cyclooxygenase, involved in production of prostaglandins

Thiocolchicoside

Act as GABAAR agonist/antagonist that induces depression of CNS &, in turn, myorelaxation.

TCC exhibits molecular structure similar to colchicine,( plant alkaloid) that binds to tubulin, induces depolymerization of microtubules, disrupts axonal transport, and inhibits mitosis

Indications Anti-Inflammatory, Analgesic, Neck and Shoulder

Dosage: One tablet OD/BD or as advised by the physician.

ADEGOPAIN

COMPETITORS


LUKOTAS-LC INTAS

MONTAIR LC TAB CIPLA

MONTEK LC SUN PHARMA

MONTRAL MICRO

TELEKAST L LUPIN

ADLAZINE-L

CompositionMontelukast : 10 mg

Levocetirizine: 5mg

Mechanism of Action

Montelukast

Selective and orally active leukotriene receptor antagonist

Inhibits the cysteinyl leukotriene (CysLT1), receptor

Levocetirizine

R-enantiomer of cetirizine

Orally active,potent, selective and long acting H1-histamine receptor antagonist with no anticholinergic activity.

Indications For relief from allergic rhinitis [seasonal or perennial] Treatment of comorbid asthma and allergic rhinitisIn patients 15 years of age and over

Dosage: Adults [>15years]: 1 Tablet OD

COMPETITORS


LEVOCET GEN X(HETERO)

L MORTUS FOURTS

RID AR CIPLA

MONTEMAC MACLEODS

TELEKAST L TAB LUPIN

ADLAZINE-L

ADLAZINE-L KID

Composition Montelukast : 4 mgLevocetirizine: 2.5mg

Mechanism of Action

Montelukast

Selective and orally active leukotriene receptor antagonist

Inhibits the cysteinyl leukotriene (CysLT1), receptor.

Levocetirizine

R-enantiomer of cetirizine

Orally active,potent, selective and long acting H1-histamine receptor antagonist with no anticholinergic activity.

Indications

For relief of symptoms of allergic rhinitis [seasonal or perennial],

Treatment of asthma

In patients 2 to 5 years of age

ADLAZINE-L KIDDosage: One tablet OD

COMPETITORS


LUKOTAS-LC INTAS

MONTAIR LC TAB CIPLA

MONTEK LC SUN PHARMA

MONTRAL MICRO

TELEKAST L LUPIN

CLAVUGONO

Composition

Cefuroxime Axetil : 500mg

Clavulanic Acid : 125 mg

Mechanism of Action

Cefuroxime Axetil

Inhibition of cell wall synthesis by binding to essential target proteins

It has two ionizable groups in physiological range (amino group in alpha-position to amide carbonyl group & carboxyl group).

Clavulanic acidIt is a β-lactam structurally related to the penicillins.

Inactivate a wide variety of β-lactamases by blocking the active sites of these enzymes.

Combination prevent destruction of cefuroxime that isa substrate for this enzyme

Indications

Pharyngitis/tonsillitis,Acute bacterial maxillary sinusitis Acute bronchitis. Uncomplicated skin and skin-structure infections Uncomplicated UTIUncomplicated gonorrhea (urethral and endocervical)

CLAVUGONO

DOSAGE: One tablet BD

COMPETITORS


PULMOCEF MICRO

ZEFU - CV FDC

BIGCEF CV BESTOCHEM FORMULAT

ALTACEF CV GLENMARK

CEROXIM XP RANBAXY

ADLORPHEN

Composition Lornoxicam : 4mgParaetamoL : 325mg

Mechanism of Action

Lornoxicam

Inhibits prostaglandin biosynthesis by blocking the enzyme Cyclo- oxygenase

Distinguished from established oxicams by relatively short elimination half-life (3 to 5 hours),

Advantageous from a tolerability standpoint

Paracetamol

NSAID, Inhibition of (COX).

Produce analgesia through a central inhibition of prostaglandin synthesis

IndicationsA nonsteroidal anti-inflammatory drug (NSAID), Moderate to severe pain, osteoarthritis, and rheumatoid arthritis. Muscle pain and Musculo skeletal pain. Low back pain. Post operative pain.Ankylosing spondylitis. Acute Sciatica

ADLORPHEN

DOSAGE: One tablet BD

COMPETITORS


LORNASAFE PLUS (4+500) MANKIND PHARMACEUTICALS PVT. LTD.

LORNICAM PLUS (4+500) ARISTO PHARMACEUTICALS PVT LTD.

LORSAID P (4+500) PIRAMAL HEALTHCARE

FLEXILOR P (4+500) GLENMARK PHARMACEUTICALS LTD.

FULACTIVE P (4+500) RANBAXY LABORATORIES LTD.,

CLAVUCAL Composition

Amoxicillin : 500 mg

Clavulanic acid : 125mg

Mechanism of Action

Amoxicillin Inhibits synthesis of bacterial cell walls. Inhibits cross-linkage between linear peptidoglycan polymer chains that make major component of the cell walls of Gram +ve & Gram -ve bacteria It has two ionizable groups in physiological range (amino group in alpha-position to amide carbonyl group & carboxyl group).

Clavulanic acid It is a β-lactam structurally related to the penicillins.

Inactivate a wide variety of β-lactamases by blocking the active sites of these enzymes. Combination may prevent amoxicillin from hydrolyzed by β-lactamase.

Indications

Infections caused by susceptible β-lactamase- producing strains of E.coli, Haemophilus influenzae, Klebsiella spp. and Staphylococcus aureus .Acute sinusitis,acute exacerbations of chronic bronchitis in adults, pneumonia and lung abscesseshuman and animal bites and clenched-fist injuries, together with procaine benzylpenicillin,UTI in children, osteomyelitis due to Haemophilus influenzae or unknown pathogen in children ≤ 5 years, together with cloxacillin &cefotaxime. Prophylaxis in contaminated surgery.

CLACUCAL

DOSAGE:Adults and children over 12 years: One Tablet TDSChildren: Tablets are not recommended in children of 12 years and under.

COMPETITORS


ADVENT tab CIPLA

AFYMOX-CLAV 625 tab SANIFY HEALTHCARE

CLAMCHEK 625 tab INDOCO

CLAMP tab DR. REDDY'S LAB

CLAVIDUR tab LUPIN

DANENTIA-AD

Composition Memantine : 10mg

Donepezil : 5 mg

Mechanism of Action

Memantine

Voltage dependent, moderate affinity uncompetitive NMDA receptor antagonist

Modulates the effects of pathologically elevated tonic levels of glutamate that may lead to neuronal dysfunction.

Donepezil

Specific and reversible inhibitor of acetylcholinesterase, the predominant acetylcholine sterase in the brain.

1000 times more potent an inhibitor of this enzyme than of butyrylcholinesterase, an enzyme that is present mainly outside the central nervous system

Indications Moderate to severe dementia related to Alzheimer’s disease

DANENTIA-AD

DOSAGE: One tablet OD in the evening prior to retiring.

COMPETITORS


DONAMEM SUN PHARMA

ALZIL-M INTAS

DONEP-M FORTE ALKEM

VATIORTH

CompositionAceclofenac: 100mg

Paracetamol: 325mg

Serratiopeptidase: 15mg

Mechanism of Action

AceclofenacIt inhibits cyclooxygenase (COX) activity and to suppress the PGE2 production by inflammatory cells, by inhibiting IL-Beta & TNF in the inflammatory cells (Intracellular Action).It blocks degeneration and stimulates synthesis of extra cellular matrix of cartilages by inhibiting the action of different cytokines. ParacetamolParacetamol is a peripherally acting analgesic and is well absorbed orally. Paracetamol produces analgesia by elevation of the pain threshold and antipyresis through action on the hypothalamic heat-regulating center.Paracetamol is equal to aspirin in analgesic and antipyretic effectiveness.

VATIORTH

Mechanism of Action

SerratiopeptidaseThis anti-inflammatory proteolytic enzyme bind to the alpha-2-macroglobulin in the blood, which helps to mask its antigenicity.Then it is slowly transferred to the site of inflammation. Serratiopeptidase hydrolyze bradykinin, histamine, serotoxin responsible for oedema.It reduces swelling improves microcirculation and expectoration of sputum. Due to this action Serratiopeptidase has anti-inflammatory, antioedemic and fibrinolytic activity and act rapidly on localized inflammation.

Indications

AceclofenacIt is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.ParacetamolThis drug is used to treat mild to moderate pain (from headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and pains) and to reduce fever.Serratiopeptidase It is proteolytic enzyme that has potent anti-inflammatory property.

VATIORTH

DOSAGE: One tablet BD or (as advised by the physician).

COMPETITORS


ACEMIZ-S LUPIN LABORATORIES LTD.

VETORY SP HETERO HEALTHCARE LTD.

AROFF-EZ UNICHEM LABORATORIES LTD.

ZYNAC-SP ZYDUS CADILA HEALTHCARE LTD.

TERIOFLAM CADILA HEALTHCARE LTD.

ADNOSYL-WIN

CompositionFerrous Bis-glycianate

eq to Elemental Iron 60mg

Zinc Bis-glycianate

eq. to elemental Zinc 15mg

Folic Acid IP 01mg

Mecobalamin JP 500mcg

Mechanism of Action

Mecobalamin: better absorbed as compared to cyanocobalamin. Used for enhanced brain function and for improvement in symptoms of neuropathy.

Ferrous Bisglycinate: Iron supplement. Involved in oxygen distribution in the body. 60 % absorbed as compared to ferrous sulphate. Zinc Bisglycinate: Increases the oral bioavailability of Zinc by 43.4 % in the body as compared to Zinc gluconate.Important role in pregnancy, in cellular metabolism and gene expression.

Folic Acid: Prevent loss of vision by preventing age related macular degeneration.

Indications Used for treatment of deficiency disorders of Vitamin B, Zinc and Iron.

ADNOSYL-WIN

DOSAGE: One tablet OD/BD or (as advised by the physician).

COMPETITORS


SAFEROZ-XT PLUS INDIA

FERIUM-XT EMCURE

LIVOGEN-XT MERCK

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