1. basic human pathology lecture #1 cellular …ocw.tufts.edu/data/51/551831.pdf1. basic human...
Post on 09-Mar-2018
216 Views
Preview:
TRANSCRIPT
1. Basic Human Pathology Lecture #1 Cellular Adaptations to Dis...
2. Definitions
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 1
3. Definitions (cont’d)
4. Review: Tissue, Cellular, and Plasma Membrane Anatomy and Te...
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 2
5. Definitions
6. Parenchyma and Stroma
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 3
7. Plasma Membrane
8. Reaction of Cells to Stimuli
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 4
9. Hypertrophy - Masseter Muscle
10. Hypertrophy
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 5
11. Hypertrophy – Skeletal Muscle
12. Left Ventricular Wall Hypertrophy of Cardiac Muscle –...
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 6
13. Hypertrophy – Cardiac Muscle
14. Nodular Hyperplasia – Prostate
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 7
15. Nodular Hyperplasia – Prostate
16. Hypertrophy and Hyperplasia
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 8
17. Hypertrophy and Hyperplasia During Pregnancy
18. Physiological Hyperplasia –
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 9
19. Physiological Hyperplasia – Endometrium of Uterus
20. Developmental causes of reduced cell mass
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 10
21. Adaptation to Environmental Stress (cont’d) – <b...
22. Adaptation to Environmental Stress (cont’d) –
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 11
23. Adaptation to Environmental Stress (cont’d)
24. Autophagy and Cell Atrophy
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 12
25. Adaptation to Environmental Stress (cont’d)
26. Adaptation to Environmental Stress
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 13
27. Local Atrophy - Disuse
28. Atrophy - Endocrine
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 14
29. Atrophy
30. Hemifacial Atrophy
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 15
31. Adaptation to Environmental Stress (cont’d)
32. Involution – Thymus Gland
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 16
33. Adaptation to Environmental Stress (cont’d)
34. Adaptation to Environmental Stress (cont’d)
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 17
35. Cellular Adaptations to Disease/Cell Injury and Death I: Sli...
36. Respiratory Epithelium Prior to Metaplasia
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 18
37. Cellular Adaptations to Disease/Cell Injury and Death I: Sli...
38. Esophageal Mucosa Metaplastic to Stratified Squamous Epithel...
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 19
39. Ductal – Squamous Metaplasia
40. Squamous Metaplasia
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 20
41. Summary of Adaptation to Environmental Stress
42. Summary
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 21
43. Cell Adaptation Key Facts
44. Reaction of Cells to Injury
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 22
45. Reaction of Cells to Injury on a Biochemical Level
46. Reaction of Cells to Injury on a Biochemical Level
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 23
47. Function of Ubiquitin in Cell Stress
48. Protein Kinesis
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 24
49. Reaction of Cells to Injury on a Biochemical Level
50. Reaction of Cells to Injury on a Biochemical Level
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 25
51. Free Calcium’s Role as a Destructive Agent
52. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 26
53. Hydropic Change
54. Hydropic Change - Leukoedema
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 27
55. Hydropic Degeneration - Leukoedema
56. Reversible Change – Cell Degeneration
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 28
57. Reversible Cellular Changes and Accumulations
58. Fatty Change
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 29
59. Fatty Change
60. Fatty Change - Liver
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 30
61. Fatty Change - Liver
62. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 31
63. Reversible Cellular Changes and Accumulations
64. Hyaline Change – Liver Cell
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 32
65. Reversible Cellular Changes and Accumulations
66. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 33
67. Labial Melanotic Macule – Focal Melanosis
68. Melanin Pigmentation – Labial Melanotic Macule
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 34
69. Reversible Cellular Changes and Accumulations
70. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 35
71. Hemosiderin in Liver Cells
72. Hemosiderin – Lung Alveoli
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 36
73. Reversible Cellular Changes and Accumulations
74. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 37
75. Reversible Cellular Changes and Accumulations
76. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 38
77. Hemochromatosis - Pancreas
78. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 39
79. Lipofuscin – Striated Muscle and Liver
80. Reversible Cellular Changes and Accumulations
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 40
81. Pathologic Calcifications
82. Metastatic Calcification Hypercalcemia - Lung
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 41
83. Pathologic Calcifications
84. Calcific Stenosis of Aortic Valve
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 42
85. Dystrophic Calcification – Medial Sclerosis
86. Dystrophic Calcification – Medial Sclerosis
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 43
87. Dystrophic Calcification – Stomach Injury
88. Dystrophic Calcification – Periapical and Pulpal Patho...
Tufts OpenCourseWare © 2008 Tufts University
Cellular Adaptations to Disease/Cell Injury and Death I
OCW: Basic Human Pathology: Parts I and II (M. Kahn) Page - 44
top related