Lab: Cellular Pathology

Cellular adaptation• Ventricular hypertrophy; Heart• Testicular atrophy; Testis• Pregnant uterus & Atrophic uterus in

elderly• Hyperplasia – Benign prostatic

hyperplasia (CP00009A)• Metaplsia – Squamous metaplasia of

cervix (CP00010A)

Ventricular hypertrophy; Heart

Testicular atrophy; Testis

Pregnant uterus & Atrophic uterus

Reversible injury• Cloudy swelling and Vacuolar Change,

Liver (CP00001A)• Fatty change; Liver• Fatty change & Mallory bodies in

Alcoholic hepatitis (CP00002A)

Intracellular Accumulation

• Fatty change; Liver• Fatty change & Mallory bodies in

Alcoholic hepatitis (CP00002A)• Anthracosis; Lung• Anthracotic Pigments; Hilar lymph

node (CP00017A)

Fatty change; Liver

Fatty change; Liver

Anthracosis; Lung

Intracellular Accumulation

• Hemosiderosis;• Hemosiderosis of liver• Hemochromatosis of pancreas

• Hemosiderin pigment; Endometrioticcyst of Ovary (CP00012A)

• Dystrophic calcification; Arterosclerosis of aorta

• Dystrophic calcification; Skin(CP00015A)

• Metastatic calcification; Kidney

Hemosiderosis; Liver

Hemochromatosis; Pancreas

Dystrophic calcification; Arterosclerosis

Intracellular Accumulation

• Lipofuscin pigment, heart (CP00011A)• Bile Pigments; Cholestasis in Liver

(CP00013A)• Metastatic melanoma in lymph nodes• Melanin Pigments;

– Malignant melanoma ofskin(CP00014A)

– Intradermal nevus (CP00014B)

Metastatic melanoma in lymphnodes

Intracellular Accumulation

• Hyaline Changes, intracellular;– Fatty change & Mallory bodies in

Alcoholic hepatitis (CP00002A)• Hyaline Changes, extracellular ;

– Leiomyoma (CP00003A)– Amyloidosis of liver (CP00003B)

Irreversible injury or death• Coagulative necrosis

• Splenic infarct• Renal infarct

• Coagulation Necrosis; Splenic infarct (CP00004 A)

Coagulative necrosis; Splenic infarct

Coagulative necrosis; Renal infarct

Irreversible injury or death• Liquefactive necrosis

• Lung abscess• Liver abscess• Brain infarct

Liquefactive necrosis; Lung abscess

Liquefactive necrosis; Liver abscess

Liquefactive necrosis; Brain infarct

Irreversible injury or death

• Caseous necrosis; Ovary, lymph nodes and Intestine

• Caseous Necrosis – lung & Pleura (CP00005A)

• Omentum; Enzymatic fat necrosis• Pancreas; Enzymatic fat necrosis• Fat Necrosis, enzymatic (CP00007A)

Caseous necrosis; Ovary

Caseous necrosis; lymph nodes and intestine

Caseous necrosis; lymph nodes

Caseous necrosis; lymph nodes

Acute hemorrhagic pancreatitis; Enzymatic fat

necrosis

Omentum; Enzymatic fat necrosis

Irreversible injury or death• Hemorrhagic necrosis of small

intestine; Gangrene; Small intestine

Gangrene; Small intestine

The end