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AC Marine Collagen PF
Tomorrow’s Vision… Today!®
Hydration + Conditioning
Technical Information:
Product Code: 20739
INCI Name: Soluble Collagen
INCI Status: Conforms
Suggested Use Levels: 1.0 – 10.0%
Suggested Applications: Hydration, Conditioning
AC Marine Collagen PF
• Collagen has become the topic of daily conversation!• Improving the skin and lips natural collagen structure • Introducing new collagen through invasive injections
• AC Marine Collagen PF consists of:• Fish derived soluble collagen • Excellent hydrating properties • Film forming benefits in a safe, reliable manner
AC Marine Collagen PF
Science
• Collagen is created by fibroblasts, specialized cells found in the dermal layer of the skin
• Fibroblasts are responsible for the production of collagen, elastin, and fibronectin that act as the structural support beams within the skin
• Fibroblasts synthesize collagen within the cell and release it through exocytosis• A process by which molecules diffuse through the cell membrane
• Once outside the cell, the collagen molecules will self-assemble, creating the same structures found in skin
AC Marine Collagen PF
Benefits
• Restore one’s youthful appearance by hydrating the skin and helping to increase its natural collagen production
• Can be easily incorporated into the water phase
• Can be used in a wide variety of personal care formulas
• Marine collagen is capitalizing on what is arguably the most profound trend in cosmetics in the last decade
AC Marine Collagen PF
Improvements in Hydration
AC Marine Collagen PF
0
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12
Baseline AC Marine Collagen PF
Pe
rce
nt
(%)
Imp
rove
me
nt
Protocol• 2 week study with 10 M/F
• Concentration: 5.0%
• Applied on volar forearms twice daily
• Improved skin hydration by 12%
• Enhance hydration levels for both skin and scalp care
Figure 1. Percent improvement in hydration following application of AC Marine Collagen PF.
Moisturization Assay
AC Marine Collagen PF
Protocol
• AC Marine Collagen PF is capable of increasing stratum corneum moisturization values after 1 hour
• AC Marine Collagen PF may be added to anhydrous systems to effectively increase epidermal moisture
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50
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10 20 30 40 50 60 70 80 90 100
Pe
rce
nt
(%)
Mo
istu
re U
pta
ke
AC Marine Collagen PBF
Hydrolyzed Collagen
Figure 2. Percent increase in moisturization following application of AC Marine Collagen PF.
Improvements in Compatability
AC Marine Collagen PF
Protocol• Concentration: 5.0%
• Increased the sensorial perception of wet combing ease by 90.0%
• Participants rated the control as increasing combability by 40.0% and the test material as increasing dry combability by 50.0%
• Useful for preventing damage and breakage which typically results from excessive combing forces during styling
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20
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Wet Combability Dry Combability
Pe
rce
nt
(%)
Imp
rove
me
nt
Control AC Marine Collagen PF
Figure 3. Percent change in Combability.
ORAC Assay
AC Marine Collagen PF
Protocol• AC Marine Collagen PF exhibited
antioxidant activity comparable to 100μM Trolox®
• AC Marine Collagen PF increased as the concentration increased, as a result we can assure that its ability to minimize oxidative stress is dose dependent
• Ingredient is not only capable of providing functional benefits but it is also capable of providing potent antioxidant benefits when added to cosmetic applications
0
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100µM Trolox 12.5µM Trolox 0.5% AC MarineCollagen PF
0.1% AC MarineCollagen PF
0.05% AC MarineCollagen PF
An
tio
xid
ant
Cap
acit
y (µ
MTE
)
Figure 4. Antioxidant capacities.
Sirius Red Fast Green Report
AC Marine Collagen PF
Protocol• Human dermal fibroblasts were seeded
into 24-well tissue culture plates
• AA2G and IGF-1 were used a positive controls
• Concentrations: 1.0%, 0.1%, 0.01%
• AC Marine Collagen PF exhibited positive collagen synthesis activity
• The increase in collagen production may lead to improvement in the dermal-epidermal junction integrity as well as an improved scaffolding matrix
2.0
0
2.3
1
1.3
0 1.8
4
1.8
8
1.7
8
50
.91
61
.37
26
.05 45
.98
46
.13
46
.32
1
10
100
1000
100µg/mL 50ng/mL 1% 0.1% 0.01%
Ascorbic Acid IGF-1 CompleteMedia
20739 AC Marine Collagen PF
Pro
tein
Co
nce
ntr
atio
n (
µg)
Collagen Proteins Non-Collagen Proteins
Figure 5. Collagen and non-collagen protein concentrations.
Sirius Red Fast Green Report
AC Marine Collagen PF
Figure 6. Percent collagen compared to non-collagen proteins.
3.92% 3.76%
4.99%3.99% 4.08% 3.84%
0%
5%
10%
15%
20%
100µg/mL 50ng/mL 1% 0.1% 0.01%
Ascorbic Acid IGF-1 CompleteMedia
20739 AC Marine Collagen PF
% C
olla
gen
/No
n-C
olla
gen
Pro
tein
s
Protocol• Human dermal fibroblasts were seeded
into 24-well tissue culture plates
• AA2G and IGF-1 were used as positive controls
• Concentrations: 1.0%, 0.1%, 0.01%
• AC Marine Collagen PF exhibited positive collagen synthesis activity
• The increase in collagen production may lead to improvement in the dermal-epidermal junction integrity as well as an improved scaffolding matrix
Technical Information:
Product Code: 20739
INCI Name: Soluble Collagen
INCI Status: Conforms
Suggested Use Levels: 1.0 – 10.0%
Suggested Applications: Hydration, Conditioning
AC Marine Collagen PF
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www.activeconceptsllc.comWhen you register, you will have access to the complete product
documentation available.
AC Marine Collagen PF
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