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NeurologyNeurology

NAPLEX

Drugs used for Convulsive Disorders

Drugs used for Convulsive Disorders

NAPLEX

PG 88

The medication lorazepam (Ativan) has which of the following pharmacological activities?

a. sedative/hypnotic

b. anticonvulsant

c. muscle relaxant

d. anxiolytic

e. all of the above

The medication lorazepam (Ativan) has which of the following pharmacological activities?

a. sedative/hypnotic

b. anticonvulsant

c. muscle relaxant

d. anxiolytic

e. all of the above

The medication lorazepam (Ativan) has which of the following pharmacological activities?

a. sedative/hypnotic

b. anticonvulsant

c. muscle relaxant

d. anxiolytic

e. all of the above

The medication lorazepam (Ativan) has which of the following pharmacological activities?

a. sedative/hypnotic

b. anticonvulsant

c. muscle relaxant

d. anxiolytic

e. all of the above

Major Types of Convulsive Disorders

Major Types of Convulsive Disorders

• Partial – generally involves only one hemisphere of the brain (initially) and asymmetrical:

Simple-no loss of consciousness

Complex-loss of consciousness

Phenytoin, carbamazepine, barbiturates, valproate

• Generalized – generally involves both hemispheres of the brain; bilateral/symmetrical:

absence, myoclonic, clonic, tonic, tonic-clonic,

Valproate, lamotrigine, carbamazepine, ethosuximide

• Status epilepticus—30 minutes of continuous seizures or five

minutes of convulsive seizures.

Lorazepam is drug of choice; midazolam or propofol

• Partial – generally involves only one hemisphere of the brain (initially) and asymmetrical:

Simple-no loss of consciousness

Complex-loss of consciousness

Phenytoin, carbamazepine, barbiturates, valproate

• Generalized – generally involves both hemispheres of the brain; bilateral/symmetrical:

absence, myoclonic, clonic, tonic, tonic-clonic,

Valproate, lamotrigine, carbamazepine, ethosuximide

• Status epilepticus—30 minutes of continuous seizures or five

minutes of convulsive seizures.

Lorazepam is drug of choice; midazolam or propofol

PG 88

Anticonvulsant DrugsAnticonvulsant Drugs AED monotherapy is preferred, but some patients do

require combination therapy. First-line AEDs for partial seizures include carbamazepine,

phenytoin, lamotrigine, valproic acid, and oxcarbazepine.

First-line AEDs for generalized absence seizures include valproic acid and ethosuximide.

First-line AEDs for tonic-clonic seizures include phenytoin, carbamazepine, and valproic acid.

Alternative AEDs include gabapentin, topiramate, levetiracetam, zonisamide, tiagabine, primidone, felbamate, lamotrigine, and phenobarbital.

AED monotherapy is preferred, but some patients do require combination therapy. First-line AEDs for partial seizures include carbamazepine,

phenytoin, lamotrigine, valproic acid, and oxcarbazepine.

First-line AEDs for generalized absence seizures include valproic acid and ethosuximide.

First-line AEDs for tonic-clonic seizures include phenytoin, carbamazepine, and valproic acid.

Alternative AEDs include gabapentin, topiramate, levetiracetam, zonisamide, tiagabine, primidone, felbamate, lamotrigine, and phenobarbital.

PG 89-90

PG 89-90

PG 89-90

Which of the following medications is NOT an inducer of the liver CYP450 system?

a. carbamazepineb. phenytoinc. valproate

d. olanzapinee. phenobarbital

Which of the following medications is NOT an inducer of the liver CYP450 system?

a. carbamazepineb. phenytoinc. valproate

d. olanzapinee. phenobarbital

Which of the following medications is NOT an inducer of the liver CYP450 system?

a. carbamazepineb. phenytoinc. valproate

d. olanzapinee. phenobarbital

Which of the following medications is NOT an inducer of the liver CYP450 system?

a. carbamazepineb. phenytoinc. valproate

d. olanzapinee. phenobarbital

Valproic acid is available in which of the following dosage forms?

I. CapsulesII. LiquidIII. Tablets

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Valproic acid is available in which of the following dosage forms?

I. CapsulesII. LiquidIII. Tablets

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Valproic acid is available in which of the following dosage forms?

I. CapsulesII. LiquidIII. Tablets

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Valproic acid is available in which of the following dosage forms?

I. CapsulesII. LiquidIII. Tablets

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

A drug specific for petit mal is:

a. clonazepam

b. diazepam

c. flurazepam

d. lorazepam

e. oxazepam

A drug specific for petit mal is:

a. clonazepam

b. diazepam

c. flurazepam

d. lorazepam

e. oxazepam

A drug specific for petit mal is:

a. clonazepam

b. diazepam

c. flurazepam

d. lorazepam

e. oxazepam

A drug specific for petit mal is:

a. clonazepam

b. diazepam

c. flurazepam

d. lorazepam

e. oxazepam

Which of the following has no known drug interaction with oral contraceptives?

a. Neurontin

b. Carbamazepine

c. Valproic Acid

d. Phenytoin

e. Topiramate

Which of the following has no known drug interaction with oral contraceptives?

a. Neurontin

b. Carbamazepine

c. Valproic Acid

d. Phenytoin

e. Topiramate

Which of the following has no known drug interaction with oral contraceptives?

a. Neurontin

b. Carbamazepine

c. Valproic Acid

d. Phenytoin

e. Topiramate

Which of the following has no known drug interaction with oral contraceptives?

a. Neurontin

b. Carbamazepine

c. Valproic Acid

d. Phenytoin

e. Topiramate

Drugs to Treat Parkinson’s Disease

Drugs to Treat Parkinson’s Disease

NAPLEX

PG 91

Drugs to Treat Parkinson Disease

Causes of Parkinson disease

Disruption of dopaminergic / cholinergic balance

Characteristics of patients (TRAP)

Slow onset; Tremor, Rigidity, Akinesia, Postural instability

Drug therapy

Goals – Mainly palliative; attempt to inhibit cholinergic and attenuate dopaminergic action

PG 91

Drugs to Treat Parkinson Disease (cont’d)

Anticholinergic Drugs. Watch for dry mouth, constipation, urinary retention, intraoccular pressure

• Procyclidine (Kemadrin)

• Trihexyphenidyl (Artane)

• Benztropine (Cogentin)

• Biperiden (Akineton)

• Diphenhydramine (Benadryl)

Bradykinesia is best defined as:

a. slow movements

b. rapid heart rate

c. narrowing of the pupil

d. excessive sweating

e. loss of desire for pleasurable

activities

Bradykinesia is best defined as:

a. slow movements

b. rapid heart rate

c. narrowing of the pupil

d. excessive sweating

e. loss of desire for pleasurable

activities

Bradykinesia is best defined as:

a. slow movementsb. rapid heart rate (tachycardia)

c. narrowing of the pupil (miosis)

d. excessive sweating (diaphoresis)

e. loss of desire for pleasurable

activities (apathy)

Bradykinesia is best defined as:

a. slow movementsb. rapid heart rate (tachycardia)

c. narrowing of the pupil (miosis)

d. excessive sweating (diaphoresis)

e. loss of desire for pleasurable

activities (apathy)

PG 91

Drugs to Treat Parkinson Disease (cont’d)

Dopaminergic Agents

• Levodopa (Larodopa, Dopar) - watch for on-off effect and B6 decreases efficacy, iron increases absorption

• Levodopa/carbidopa (Sinemet) - wait 8 hours if converting from

levodopa. Cut levodopa dose to 25% of original.

• Amantadine (Symmetrel) - increases release of dopamine stores (hypersensitivity); antiviral properties - antiviral for flu

• Ergot-derived dopamine receptor agonists - stimulate dopamine

receptors; (a) bromocriptine mesylate (Parlodel), and (b)

pergolide mesylate (Permax)

PG 92

Drugs to Treat Parkinson Disease (cont’d)

• Nonergot dopamine receptor agonists - stimulate dopamine

receptors; (a) pramipexole (Mirapex), (b) ropinirole (Requip), and

(c) rotigotine (Neupro Transdermal)

--- ropinirole approved to Restless Leg Syndrome

• COMT inhibitors - adjunct that extends the action of

levodopa/carbidopa; (a) Tolcapone (Tasmar), monitor hepatic

function, and (b) entacapone (Comtan)

---no monotherapy

• MAO-B inhibitor-adjunct that decreases breakdown of dopamine; (a) selegiline (Eldepryl, Emsam, Zelapar), (b) rasagiline (Azilect)

---watch for MAO-inhibitor drug interactions

What information should the doctor know prior to initiating Mirapex in a patient with Parkinson’s Disease?

I. Decrease the levodopa dose by 20-30% when initiating Mirapex

II. Patient must wear patch for 24 hours for efficacy

III. Monitor for serious cardiac side effects

a. I only

b. III only

c. I and II only

d. II and III only

e. I, II, III

What information should the doctor know prior to initiating Mirapex in a patient with Parkinson’s Disease?

I. Decrease the levodopa dose by 20-30% when initiating Mirapex

II. Patient must wear patch for 24 hours for efficacy

III. Monitor for serious cardiac side effects

a. I only

b. III only

c. I and II only

d. II and III only

e. I, II, III

What information should the doctor know prior to initiating Mirapex in a patient with Parkinson’s Disease?

I. Decrease the levodopa dose by 20-30% when initiating Mirapex

II. Patient must wear patch for 24 hours for efficacy

III. Monitor for serious cardiac side effects

a. I only

b. III only

c. I and II only

d. II and III only

e. I, II, III

What information should the doctor know prior to initiating Mirapex in a patient with Parkinson’s Disease?

I. Decrease the levodopa dose by 20-30% when initiating Mirapex

II. Patient must wear patch for 24 hours for efficacy

III. Monitor for serious cardiac side effects

a. I only

b. III only

c. I and II only

d. II and III only

e. I, II, III

Alzheimer's DrugsAlzheimer's Drugs

NAPLEX

p. 118

Drugs for Alzheimer’s Disease

Cholinesterase inhibitors: all enhance cholinergic activity• Donepezil (Aricept)• Galantamine (Razadyne) (Reminyl – D/C))• Rivastigmine (Exelon)

Glutamate antagonists• Memantine (Namenda)

Miscellaneous agents• Vitamin E• Selegiline (Eldepryl)

p. 118

Cholinesterase Inhibitors DosingCholinesterase Inhibitors Dosing

Drug Starting dose

Time before Increasing dose

Increase dose by

Max dose

Donepezil (Aricept)

5mg QHS 6 weeks 5mg QHS 10mg QHS

Rivastigmine (Exelon)

1.5mg BID 2 weeks 1.5mg BID

6mg BID

Galantamine (Razadyne)

4mg BID 4 weeks 4mg BID Recommen-ded range of 16-24 mg a day.

• Dose dependent side effects require titration• Start low and take in steps to avoid side effects

p. 118

Drugs for Alzheimer’s Disease

Adverse Effects

Cholinesterase inhibitors:• Hepatotoxicity• Cholinergic effects (N/D, anorexia, salivation)• Bradycardia• Headache

Glutamate antagonists• Hypertension• Tachycardia• Insomnia

p. 118

Reference Sources for Pharmacists

Reference Sources for Pharmacists

NAPLEX

PG 399PG

Literature ReviewLiterature Review Primary literature Original journal articles

(research reports, case reports, editorials); serves as information for development of secondary and tertiary literature resources

Secondary literature Indexing and abstracting services (e.g. MEDLINE, IPA, EMBASE, Cochrane)

Tertiary literature Textbooks and review articles; summarize and interpret primary literature

Primary literature Original journal articles (research reports, case reports, editorials); serves as information for development of secondary and tertiary literature resources

Secondary literature Indexing and abstracting services (e.g. MEDLINE, IPA, EMBASE, Cochrane)

Tertiary literature Textbooks and review articles; summarize and interpret primary literature

PG 399

ReferencesReferences

USP-NF Official monographs for drug structure, solubilities, assays

and therapeutic category Limited info on dosage, dosage forms

USP DI (Micromedex) Three volume set

• I---DI for healthcare professionals (“package insert”) 11,000 drug products

• II---Advice for patients – easy to understand• III---Approved Drug products, legal requirements, Orange book

FDA Orange Book (electronic - 2004) Bioequivalence information

USP-NF Official monographs for drug structure, solubilities, assays

and therapeutic category Limited info on dosage, dosage forms

USP DI (Micromedex) Three volume set

• I---DI for healthcare professionals (“package insert”) 11,000 drug products

• II---Advice for patients – easy to understand• III---Approved Drug products, legal requirements, Orange book

FDA Orange Book (electronic - 2004) Bioequivalence information

PG 399

ReferencesReferences

Remington’s “Pharmacy encyclopedia” – pharmacology, theoretical

science, sterilization, practical pharmacy practice

Facts and Comparisons Rx and OTC by therapeutic category – monthly updates

AHFS Good info on drug pharmacology – intended for institutional

Blue Book / Red Book Drugs / OTC / Cosmetics Prices, NDC numbers, manufacturer address

Remington’s “Pharmacy encyclopedia” – pharmacology, theoretical

science, sterilization, practical pharmacy practice

Facts and Comparisons Rx and OTC by therapeutic category – monthly updates

AHFS Good info on drug pharmacology – intended for institutional

Blue Book / Red Book Drugs / OTC / Cosmetics Prices, NDC numbers, manufacturer address

PG 399

ReferencesReferences Physician’s Desk Reference (PDR)

White pages—manufacturer index of products Pink pages—product names by trade name Blue pages—products by therapeutic category Yellow pages—generic and trade names with colored product

ID Martindale’s

Comprehensive drug lists (think foreign products - EUP) Merck Manual

Describes diseases by symptoms Merck Index

Listing of chemicals Drugs in Pregnancy and Lactation (Briggs)

Gold standard

Physician’s Desk Reference (PDR) White pages—manufacturer index of products Pink pages—product names by trade name Blue pages—products by therapeutic category Yellow pages—generic and trade names with colored product

ID Martindale’s

Comprehensive drug lists (think foreign products - EUP) Merck Manual

Describes diseases by symptoms Merck Index

Listing of chemicals Drugs in Pregnancy and Lactation (Briggs)

Gold standard

PG 399

A comparison of the relative daily cost of six brands of HCTZ can most easily be obtained by using the:

a. Martindale’s Extra Pharmacopeia b. Facts and Comparisons

c. Red Book/Blue Book d. Merck Index

e. Remington’s

A comparison of the relative daily cost of six brands of HCTZ can most easily be obtained by using the:

a. Martindale’s Extra Pharmacopeia b. Facts and Comparisons

c. Red Book/Blue Book d. Merck Index

e. Remington’s

A comparison of the relative daily cost of six brands of HCTZ can most easily be obtained by using the:

a. Martindale’s Extra Pharmacopeia (drug lists foreign)

b. Facts and Comparisons (therapuetics)

c. Red Book/Blue Book (prices & NDCs)

d. Merck Index (list of chemicals)

e. Remington’s (pharmacology)

A comparison of the relative daily cost of six brands of HCTZ can most easily be obtained by using the:

a. Martindale’s Extra Pharmacopeia (drug lists foreign)

b. Facts and Comparisons (therapuetics)

c. Red Book/Blue Book (prices & NDCs)

d. Merck Index (list of chemicals)

e. Remington’s (pharmacology)

Which of the following items is NOT presented in USP DI Volume III:

a. Description of therapeutic uses for drugs

b. List of orphan drugs

c. Description of good pharmacy compounding practices

d. Definition of official storage conditions

e. The Federal Controlled Substances Act

Which of the following items is NOT presented in USP DI Volume III:

a. Description of therapeutic uses for drugs

b. List of orphan drugs

c. Description of good pharmacy compounding practices

d. Definition of official storage conditions

e. The Federal Controlled Substances Act

Which of the following items is NOT presented in USP DI Volume III:

a. Description of therapeutic uses for drugsb. List of orphan drugs (Martidale)

c. Description of good pharmacy compounding practices (“a handbook on compounding”)

d. Definition of official storage conditions(Remington's or AHFS)

e. The Federal Controlled Substances Act (Guide to Federal Pharmacy Law)

Which of the following items is NOT presented in USP DI Volume III:

a. Description of therapeutic uses for drugsb. List of orphan drugs (Martidale)

c. Description of good pharmacy compounding practices (“a handbook on compounding”)

d. Definition of official storage conditions(Remington's or AHFS)

e. The Federal Controlled Substances Act (Guide to Federal Pharmacy Law)

Compilation of information concerning parenteral drug solutions are found in:

a. Goodman and Gilman

b. Martindale’s

c. Merck Index

d. Remington’s

e. Trissel’s

Compilation of information concerning parenteral drug solutions are found in:

a. Goodman and Gilman

b. Martindale’s

c. Merck Index

d. Remington’s

e. Trissel’s

Compilation of information concerning parenteral drug solutions are found in:

a. Goodman and Gilman

b. Martindale’s

c. Merck Index

d. Remington’s

e. Trissel’s

Compilation of information concerning parenteral drug solutions are found in:

a. Goodman and Gilman

b. Martindale’s

c. Merck Index

d. Remington’s

e. Trissel’s

Solubility data for potassium gluconate will be found in:

I. Merck IndexII. USP-NFIII. Remington’s

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Solubility data for potassium gluconate will be found in:

I. Merck IndexII. USP-NFIII. Remington’s

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Solubility data for potassium gluconate will be found in:

I. Merck IndexII. USP-NFIII. Remington’s

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Solubility data for potassium gluconate will be found in:

I. Merck IndexII. USP-NFIII. Remington’s

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Contraindications for a commercial prescription drug may be located in:

I. PDRII. Merck ManualIII. USP-NF

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Contraindications for a commercial prescription drug may be located in:

I. PDRII. Merck ManualIII. USP-NF

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Contraindications for a commercial prescription drug may be located in:

I. PDRII. Merck ManualIII. USP-NF

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Contraindications for a commercial prescription drug may be located in:

I. PDRII. Merck ManualIII. USP-NF

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

PG.40PG.40

What is the generic name for Actos?

a. Indinavir

b. Glyburide

c. Pioglitazone

d. Rosiglitazone

e. Zafirlukast

What is the generic name for Actos?

a. Indinavir

b. Glyburide

c. Pioglitazone

d. Rosiglitazone

e. Zafirlukast

The pharmacist should inform the patient that the Actos:

a. must be taken first thing in the morning before breakfastb. must be taken with the evening meal c. must be taken approximately 1 h before

bedtime d. requires consumption of at least 1 glass of

water e. may be taken any time during the day

The pharmacist should inform the patient that the Actos:

a. must be taken first thing in the morning before breakfastb. must be taken with the evening meal c. must be taken approximately 1 h before

bedtime d. requires consumption of at least 1 glass of

water e. may be taken any time during the day

The pharmacist should inform the patient that the Actos:

a. must be taken first thing in the morning before breakfastb. must be taken with the evening meal c. must be taken approximately 1 h before

bedtime d. requires consumption of at least 1 glass of

water e. may be taken any time during the day

The pharmacist should inform the patient that the Actos:

a. must be taken first thing in the morning before breakfastb. must be taken with the evening meal c. must be taken approximately 1 h before

bedtime d. requires consumption of at least 1 glass of

water e. may be taken any time during the day

Which of the following cold remedies would be suitable for Ms Doolittle’s cough?

I. Robitussin DMII. Robitussin ACIII. Robitussin PE

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Which of the following cold remedies would be suitable for Ms Doolittle’s cough?

I. Robitussin DMII. Robitussin ACIII. Robitussin PE

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Which of the following cold remedies would be suitable for Ms Doolittle’s cough?

I. Robitussin DMII. Robitussin ACIII. Robitussin PE

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Which of the following cold remedies would be suitable for Ms Doolittle’s cough?

I. Robitussin DMII. Robitussin ACIII. Robitussin PE

a. I onlyb. III onlyc. I and II onlyd. II and III onlye. I, II, and III

Which one of the following analgesics is most suitable to relieve the fever and headache of Ms. Doolittle’s 3-year-old boy?

a. Anacin

b. Ascriptin

c. Bayer PM

d. Panadol

e. Bayer Children’s Aspirin

Which one of the following analgesics is most suitable to relieve the fever and headache of Ms. Doolittle’s 3-year-old boy?

a. Anacin

b. Ascriptin

c. Bayer PM

d. Panadol

e. Bayer Children’s Aspirin

Which one of the following analgesics is most suitable to relieve the fever and headache of Ms. Doolittle’s 3-year-old boy?

a. Anacinb. Ascriptin

c. Bayer PM d. Panadol (acetaminophen) e. Bayer Children’s Aspirin

Reye Syndrome – 1970s – caused by inborn error of metabolism or toxin – peak onset age 6,

Which one of the following analgesics is most suitable to relieve the fever and headache of Ms. Doolittle’s 3-year-old boy?

a. Anacinb. Ascriptin

c. Bayer PM d. Panadol (acetaminophen) e. Bayer Children’s Aspirin

Reye Syndrome – 1970s – caused by inborn error of metabolism or toxin – peak onset age 6,

Which one of the following drug products has the same active ingredient as Calan?

a. Dyazide

b. Effexor

c. Isordil

d. Plendil

e. Verelan

Which one of the following drug products has the same active ingredient as Calan?

a. Dyazide

b. Effexor

c. Isordil

d. Plendil

e. Verelan

Which one of the following drug products has the same active ingredient as Calan?

a. Dyazide

b. Effexor

c. Isordil

d. Plendil

e. Verelan

Which one of the following drug products has the same active ingredient as Calan?

a. Dyazide

b. Effexor

c. Isordil

d. Plendil

e. Verelan

Bactrim DS is probably being used to treat which of the following microorganisms?

a. Chlamydia pneumoniaeb. Clostridium difficile c. Enterococcus faecalisd. Escherichia colie. Pseudomonas aeruginosa

Bactrim DS is probably being used to treat which of the following microorganisms?

a. Chlamydia pneumoniaeb. Clostridium difficile c. Enterococcus faecalisd. Escherichia colie. Pseudomonas aeruginosa

Bactrim DS is probably being used to treat which of the following microorganisms?

a. Chlamydia pneumoniaeb. Clostridium difficile c. Enterococcus faecalisd. Escherichia colie. Pseudomonas aeruginosa

Bactrim DS is probably being used to treat which of the following microorganisms?

a. Chlamydia pneumoniaeb. Clostridium difficile c. Enterococcus faecalisd. Escherichia colie. Pseudomonas aeruginosa

Which of the following lab alterations would you expect to see in Ms. Brown as a result of starting the Bactrim DS?

a. Increased INRb. Decreased INR c. Increased potassium d. Decreased potassiume. Increased sodium

Which of the following lab alterations would you expect to see in Ms. Brown as a result of starting the Bactrim DS?

a. Increased INRb. Decreased INR c. Increased potassium d. Decreased potassiume. Increased sodium

Which of the following lab alterations would you expect to see in Ms. Brown as a result of starting the Bactrim DS?

a. Increased INRb. Decreased INR c. Increased potassium d. Decreased potassiume. Increased sodium

Which of the following lab alterations would you expect to see in Ms. Brown as a result of starting the Bactrim DS?

a. Increased INRb. Decreased INR c. Increased potassium d. Decreased potassiume. Increased sodium

A patient recently moved to the United States from England. She brings in her prescription bottle and asks the pharmacist if they carry the antibiotic that she has been taking for a UTI. Which of the following references could be used by the pharmacist to determine if there is an equivalent antibiotic available in the United States?

a. Facts and Comparisonsb. Martindalec. Merck Indexd. PDRe. Red Book

A patient recently moved to the United States from England. She brings in her prescription bottle and asks the pharmacist if they carry the antibiotic that she has been taking for a UTI. Which of the following references could be used by the pharmacist to determine if there is an equivalent antibiotic available in the United States?

a. Facts and Comparisonsb. Martindalec. Merck Indexd. PDRe. Red Book

A patient recently moved to the United States from England. She brings in her prescription bottle and asks the pharmacist if they carry the antibiotic that she has been taking for a UTI. Which of the following references could be used by the pharmacist to determine if there is an equivalent antibiotic available in the United States?

a. Facts and Comparisonsb. Martindalec. Merck Indexd. PDRe. Red Book

A patient recently moved to the United States from England. She brings in her prescription bottle and asks the pharmacist if they carry the antibiotic that she has been taking for a UTI. Which of the following references could be used by the pharmacist to determine if there is an equivalent antibiotic available in the United States?

a. Facts and Comparisonsb. Martindalec. Merck Indexd. PDRe. Red Book

THANKS!!!!!THANKS!!!!!

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