nutrigenomics
Post on 31-Dec-2015
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Nutrigenomics
KNH 413
Nutrigenomics and Disease
CancerUse of omega-3 & EPA for rare typesPredicting benefit difficult in other types
Responders and non-responders
Colon cancerFolate intake and alcoholFruits and vegetables
Breast cancerAntioxidants
Nutrigenomics and Disease
ObesitySusceptibility with conducive environmentPolygenic traitPromising research
Perilipin Serotonin receptor gene promoter
Nutrigenomics and Disease
Thrifty Gene hypothesisMetabolic status and fetal adaptation predict disease
in adulthoodProneness to metabolic syndrome, obesity, diabetes,
CVD
Nutrigenomics and Disease
DiabetesFocus on type 2Metabolic syndrome, insulin resistanceGLUT 2PPARyAPOE
Nutrigenomics and Disease
Cardiovascular DiseaseDyslipidemiasFamilial hypercholesterolemiaPUFAs on HDLOmega-3s and TGOmega-6s and inflammation
Dietetics and Genetics
Understanding nutrient interactions and genes
Future of diet counseling
Beware of home testing kits“DNA diet”ScionaCostly
EGAPP ProjectTo establish a coordinated process Evaluation of genomic applications and
practice/preventionq
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