bacterial infections 1 - gmch
TRANSCRIPT
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BACTERIAL INFECTIONS
•Bacterial flora of normal skin Resident flora -Grow on skin
Stable in number Attached to skin
Transient flora -Unable to grow on skin Exogenous source Unattached to skin Transient residents
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Composition of normal flora
Aerobic-Gram positive cocci (Staphylococcus) Gram positive bacilli Gram negative cocci (Acinetobacter)
Anaerobic-Propionibacterium
P.acnes P.granulosum P.avidum
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Bacterial infections Impetigo Ecthyma Folliculitis (All caused by staphylococci Furunculosis
streptococcus) Carbuncle Erysipelas Cellulitis Erythrasma caused by corynebacterium
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Impetigo -Superficial, contagious
infection of skin
- Children
Two varieties-
-Bullous
-nonbullous
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Etiology Non bullous
-Staph./ Strept.
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Non bullous Impetigo
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Non bullous Impetigo
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Bullous impetigo - S. aureus
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Bullous impetigo
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Pathology -Intra epidermal bulla
-Numerous neutrophils
-Few acantholytic cells
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Clinical features -Erythematous,
vesiculo-pustules
with discharge
-Honey/straw-coloured/
golden yellow granular crust
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-Peripheral extension with
central healing
-Healing without scarring
- Regional lymphadenitis
-Fever
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Ecthyma
-Deeper variant
-Chocolate colored crust
- indurated base with
surrounding erythema
-Adherent crust
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Ecthyma
Beneath crust -purulent ulcer
Healing with scarring
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Ecthyma Sites :
Lower limb
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Folliculitis
-Inflammation of hair follicle
Etiology-
-S. aureus (mainly)
-Gram negative rods
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Folliculitis
Predisposing factors -Seborrhoeic dermatitis
-Trauma (sharing)
-Emotional stress
-Exfoliative dermatitis,
steroid intake, DM
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Folliculitis
Clinical Features -Single/ multiple
-Dome shaped papules/
pustules hair in centre
-Surrounding erythema
-Tender area
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Clinical Features -Inflammatory indurated
nodule in few days
-Fever,
constitutional symptoms
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Superficial folliculitis
(Bockhart’s Impetigo) Terminal part of hair follicles
i.e.ostia
Pustules involving scalp,
hair margin,extremities
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Superficial folliculitis
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Deep folliculitis (involving whole length
of hair follicle)
Sites of predilection:
-beard area
(Sycosis barbae)
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Folliculitis
Herpes Simplex
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Folliculitis
Pityrosporum ovale
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Furunculosis (Boils)
Involvement of hair follicle
and perifollicular region
(dermis & subcutaneous) S. aureus main agent
Furunculosis =
folliculitis+perifolliculitis
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Abcess
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Carbuncle
-Deeper infection of
contiguous follicles
with S. aureus
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Carbuncle Clinical Features
Firm, tender, indurated lump
Multiple openings
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Sites Back of neck, shoulder,
hips, thighs
-Healing with scar
-Associated with DM,
exfoliative dermatitis etc.
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Erysipelas
Upper sub-cutaneous &
lymphatic tissue involvement
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Etiology -Steptococcal/Staph.
-Entry through wound,
injury
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Clinical Features -Swelling
Spreads peripherally
Overlying skin- Tense
(Peau‘d’ orange )
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Sites -Abd. wall (infants) -Lower leg,face,ear (adults) -Face/limb (child)
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Cellulitis -Acute infection of
deeper subcutaneous tissue
-Streptococcus / S.aureus
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Cellulitis -Deeper variant of Erysipelas
-Indistinct border
-Presence of malaise, fever
-Association with DM
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Necrotizing Fascitis
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Management of Staph. & Strept. Infections •Local hygiene
•Treatment of Immuno-compromising factors
- steroid
- malnutrition
- DM
•Avoid insect bites
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Topical treatment - Bacitracin
- Framycetin 1%
- Polymyxin B
- 1% Gentian violet
- Neomycin
- Mupirocin
- Sodium fusidate
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Systemic treatment
-Penicillinase stable penicillin's
-Erythromycin i.e. Macrolides
-Cotrimoxazole
-Cephalosporins