Bio 414LS Week 2Lecture:Normal Fly Development& Microscopy

Activity:Disc dissection

Lecture:Fly Genetics, Husbandry & Handling

Activity:Virgining

Assessment:Sabotage!

Reading:Tyler ManualChapter 8

DrosophilaGuide

Reading:Fly PushingChapter 1

Activity:Virgining

Activity:Virgining

Activity:Virgining

The lecture and activity are to achieve these objectives:*Students will be able to briefly describe how a fertilized egg will develop into a 1st instar larvae with regard to patterning, germ layers & germ cells.*Students will be able to describe the life cycle with regard to timing of stages. *Students will be able to identify the parts of an adult wing. *Students will be able to dissect and identify larval imaginal discs by shape and position.

The lecture and activity are to achieve these objectives:*Students will be able to explain the relationship between genome sequence, genetic & cytological maps across the chromosome.*Students will be able to predict (in a very, very rough way) where their mutation lies on the genome by comparing the known genetic and/or cytological map position for their gene.*Students will be able to describe what an adult fly would look like given a genotype.*Students will be able to explain the differences between Drosophila and human dosage compensation*Students will be able to explain what balancers are used for and which is used for which chromosome.*Students will be able to sort and show the difference between sexes & virgins.*Students will be able to set up the light source & dissecting microscope.

Formative Assessment

Bio 414LS Week 2Lecture:Normal Fly Development& Microscopy

Activity:Disc dissection

Lecture:Fly Genetics, Husbandry & Handling

Activity:Virgining

Assessment:Sabotage!

Reading:Tyler ManualChapter 8

DrosophilaGuide

Reading:Fly PushingChapter 1

Activity:Virgining

Activity:Virgining

Activity:Virgining

The lecture and activity are to achieve these objectives:*Students will be able to briefly describe how a fertilized egg will develop into a 1st instar larvae with regard to patterning, germ layers & germ cells.*Students will be able to describe the life cycle with regard to timing of stages. *Students will be able to identify the parts of an adult wing. *Students will be able to dissect and identify larval imaginal discs by shape and position.

The lecture and activity are to achieve these objectives:*Students will be able to explain the relationship between genome sequence, genetic & cytological maps across the chromosome.*Students will be able to predict (in a very, very rough way) where their mutation lies on the genome by comparing the known genetic and/or cytological map position for their gene.*Students will be able to describe what an adult fly would look like given a genotype.*Students will be able to explain the differences between Drosophila and human dosage compensation*Students will be able to explain what balancers are used for and which is used for which chromosome.*Students will be able to sort and show the difference between sexes & virgins.*Students will be able to set up the light source & dissecting microscope.

Summative AssessmentBig course objective to match:Students will be able to design an experiment to identify a mutation by mapping techniques and illustrate how that mutation in the genome could affect a protein and how that change could cause a phenotype. (Synthesis & Application)