blood component and sis
TRANSCRIPT
-
8/8/2019 Blood Component and sis
1/29
Blood component and
Hemapheresis blood component blood component bloodcomponent Hemapheresis Hemapheresis Hemapheresis
-
8/8/2019 Blood Component and sis
2/29
blood component
blood component
bloodcomponent
Hemapheresis Hemapheresis Hemap
-
8/8/2019 Blood Component and sis
3/29
-
8/8/2019 Blood Component and sis
4/29
- - Double bag , Triple bag , Quadupl
bag- 1,800 RPM 7 - 3,000 RPM 10
:- :- :- cryoprecipitate
-
8/8/2019 Blood Component and sis
5/29
Blood componentPlatelet Concentrate (PC)Fresh Frozen Plasma (FFP)
CryoprecipitateCryo-remove plasma (CRP)
-
8/8/2019 Blood Component and sis
6/29
P latelet Concentrate 20c 20c (60 70 ml)
, 1-6 c 72 hrs20 24c 5 days5.5 x 1010 /
-
8/8/2019 Blood Component and sis
7/29
IndicationSpontaneous bleeding (< 20,000/ul) Aplastic anemia,Acute leukem
Pt. ChemotherapeuPt. Surgery ITP , DIC
-
8/8/2019 Blood Component and sis
8/29
Plt Alloimmunization ABO , Plt Ag,HAg.
-
8/8/2019 Blood Component and sis
9/29
0.1 unit/kg
Plt ABO
Plt O
-
8/8/2019 Blood Component and sis
10/29
Fresh Frozen Plasma Whole blood PC-18 c in 8 hrs (1 yr)
Coagulation factor
-
8/8/2019 Blood Component and sis
11/29
CryoprecipitateFFP 200 mlFreezed in 1 hr thaw 1-6c
(10-15 ml)Freezed - 30c ( 1 yr)Fibrinogen , Factor V , Factor VIII
Willebrand s factorFactor XIII
-
8/8/2019 Blood Component and sis
12/29
IndicationHemophilia AVon Willebrand s disease
DIC FFP
-
8/8/2019 Blood Component and sis
13/29
Cryo-remove plasma= age plasmaFactor IX, Factor X, prothrombin
complaxPlasma expander
-
8/8/2019 Blood Component and sis
14/29
Packed Red Cell- 1-6c -
- Hct
-
8/8/2019 Blood Component and sis
15/29
Leukocyte Reduced RBC
(LR-RBCs)LR-RBCs = WBC < 5X108(NHFTR)Hct 85%
-
8/8/2019 Blood Component and sis
16/29
Leukocyte-deplete bloodLeukocyte-deplete blood = WBC 1,500 x109 / LWBC > 100 X 109 / L
-
8/8/2019 Blood Component and sis
22/29
PlateletpheresisSingle donor platelet (SDP)
-
8/8/2019 Blood Component and sis
23/29
ComplicationDeath 3/10,000 :-cardiacarrhythmia, ARDS, Anaphylaxis
Vas.Perforation , sepsis, Thrombosis,hemorrhage
-
8/8/2019 Blood Component and sis
24/29
2. Vas. injury- Vas. Perforation- Thrombosis
-Deep hematoma- AV fistula
-
8/8/2019 Blood Component and sis
25/29
3 . Pharmacodynamic
alteration- Antibiotic- Antiepileptic
- Digitalis
-
8/8/2019 Blood Component and sis
26/29
-
8/8/2019 Blood Component and sis
27/29
5. Hypovolumia- > 15% of bl. Volume- IV replacement
-
8/8/2019 Blood Component and sis
28/29
6. Res. distress- minor allergic reaction- Generalized urticarial reaction
- Ethylene oxide gas- FFP (Complement activation)- Antihistamine , Steroids
-
8/8/2019 Blood Component and sis
29/29
7. Infection- FFP (bl. born disease)- globulin
- Steroid