cdti funding: from seminconductors to digital healthphantomsfoundation.com/imaginenano/2018/... ·...

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CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTH This report is solely for the internal use of potential partner personnel. No part of it may be circulated, quoted, or reproduced for distribution outside the potential partner organization without prior written approval from AlphaSIP Group. This material was used by AlphaSIP Group during an oral presentation; it is not a complete record of the discussion.

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Page 1: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

CDTI FUNDING:

FROM SEMINCONDUCTORS

TO DIGITAL HEALTH

This report is solely for the internal use of potential partner

personnel. No part of it may be circulated, quoted, or reproduced

for distribution outside the potential partner organization without

prior written approval from AlphaSIP Group. This material was

used by AlphaSIP Group during an oral presentation; it is not a

complete record of the discussion.

Page 2: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

BOSTON – MADRID – ZARAGOZA STRICTLY CONFIDENTIAL

AlphaSIP

• Advanced electronic medical diagnostics laboratory founded in 2008.

• Experts in infectious respiratory diseases and antibiotic resistance (PneumoSIP)

• Winner of the SME Instrument Phase 2 of the European Commission (Top 10 largest projects)

• We develop point-of-care diagnostics devices, based on nanoelectronics, lateral-flow and microfluidics, toprovide immediate and reliable results. Patented DNA based Molecular Dx

• Only Spanish company approved by Traffic Department (DGT) in drug detection

• Partnerships with national and international Universities, Technological Centers and Hospitals such asHarvard University, Universidad Complutense de Madrid, Autónoma Barcelona, University of Zaragoza,National Center for Microelectronics, CSIC- Consejo Superior de Investigaciones Científicas, CEEI Aragón,Clinical Hospitals, Miguel Servet, La Paz, Can Ruti, Clinic, La Fe and Instituto de Salud San Carlos

• Extensive market know-how and continuous investment in R&D (More than 10 European projects)

• Direct investment of more than 14 Million EUR in Product R&D (Up to 18 Million in conjunction with Bosch,ST, Philips, NXP)

• 120 exclusive patent licenses and 10 own patents

• Team of 32 employees (PhD & Engineers) and external researchers in cooperation projects.

Page 3: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

Madrid - Zaragoza - USA

Company Overview

Molecular Diagnostics

Antibiotic resistance & Infectious Diseases

R&D Line

R&Dconsulting projects

DOA Line

Drugs of Abuse Detection

2

Engineering

Page 4: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

Product Portfolio 2018 in the market

DRUG TESTERSDrug SIP

SME INSTRUMENTPhase2

PneumoSIP

Pilot Line IA ECSEL& Lighthouse

Initiave

Advance Bio & Nanoelectronics

Engeneering

CDTI NEOTEC 2008 “SENDA” ENABLE FOLLOW

ON 14M EUR INVESTMENT IN R&D & 10 Patents

Page 5: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

Madrid - Zaragoza - USA

Molecular diagnostics

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Page 6: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

pneumosipdx.com

3

Page 7: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

•Why Pneumonia?

Each year 3,4 million cases of

pneumonia are diagnosed in

Europe, costing more than € 10bn

www.alphasip.es

Madrid - Zaragoza - USA

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Page 8: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

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PneumoSIP SystemPneumoSIP is a system that combines all manual laboratory steps for PCR detection

• Robotic arm and automatic pipette for preparationand pre-PCR tasks

• Thermocycler and fluorescence detector for qPCR

• Cross-contamination prevention flow system

• Internal and external bar code reader / QR

• Touch screen

Page 9: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

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PneumoSIP SystemPneumoSIP uses its own consumables that contains all the necessary reagents in a safe way

• Made in white room, under ISO13485

• Sealed to maintain reagent freshness until testtime

• Cost-effective, adaptable to variety of panels

• Includes bar codes / QR for identification

• Contains elements in patent process

Page 10: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

Madrid - Zaragoza - USA

DOA LineDrugs of Abuse Detection Line

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Page 11: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

DOA LineWe have developed the FirstSafety Device for Rapid DrugDetection in Saliva.

Madrid - Zaragoza - USA

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1. MOBILITY 4.0 (Thermostated, Saliva)2. DrugSIP DUAL Medical (Saliva & Urine)3. DrugSIP Manual

Page 12: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

DOA ApproachBiochemical research has positioned us as the first Spanish company in Drug of Abuse Detection knowledge

www.alphasip.es

Madrid - Zaragoza - USA

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Page 13: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

Madrid - Zaragoza - USA

R&D Pilot Line 4.0

IMPACT

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Page 14: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

R&D Line: Manufacturing 4.0

AlphaSIP is the only Spanish companypresent in the Pilot Line of EuropeanManufacturing Ecsel InForMed, thatallows large scale manufacturing of chipsin the facilities of Philips and Medtronics

AlphaSIP has the support of Cerler GlobalElectronics as a priority manufacturer

Madrid - Zaragoza - USA

18

Manufacturing and Distribution

Establish strategic partnerships,a number of large distributors are

searching for such products

Page 15: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

www.alphasip.es

Madrid - Zaragoza - USA

CDTI Funding

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Page 16: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

Year 1 Year 3 Year 5 Year 7

Proof of concept

Colon Cancer

with CEA

AlphaSIP

established

ENIAC CAJAL4EU Project

. 25 MILL EUR, 30

partners, 9 countries

Licensed out 400 patents

from Nantero

CDTI SENDA D-Dimer

chip generation I.

ENIAC SILVER project

12MILL EUR Cleantech

Nanocardiococo Mill

EUR Clinical Essay

Innpacto

AvanSurf CIEN

CATRENE 3DFF

Ecsel Silense

SME Instrument

Phase II Pneumosip

Year 11

ECSEL - Informed

Penta 2 ESAIR Infineon

“Pending National GO”

11 Years of Evolution

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www.alphasip.es

Beyond Core Business Line

CDTI CIEN “Avansurf” has helped to enternew business niche like cleantech, energyfinance

PID will yield to IoT works with Infineonlead business IoT

Madrid - Zaragoza - USA

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CDTI IMPACT

NEOTEC SENDA: Proof of concept new CMOS CNTs Based

Page 18: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

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8Sources: The World Nanotechnology Market 2006; Nanotechnology Market Forecast to 2011; Elaboración propia

BioMEMS* (BioMEMS = BioMicroelectromechanical Devices) abarcan desde el tamaño de un SIM de teléfono móvil hasta 1000 veces el tamaño de un Globulo Rojo

Thanks to coordinate large projects AlphaSIP is part

of JTI ECSEL Governing Board (5 Bn EUR)

Page 19: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

SAMPLE

PREPARATIONTRANSDUCTION

BIOSENSORBIOCHEMISTRYELECTRONIC

SYSTEM

DIAGNOSIS

EQUIPMENT

AlphaSIP designs, patents and outsourcesmanufacture of medical nanotechnology (fabless)

Page 20: CDTI FUNDING: FROM SEMINCONDUCTORS TO DIGITAL HEALTHphantomsfoundation.com/IMAGINENANO/2018/... · 21 6 tips: Learnt Lessons CDTI is a real way of financing new start-up businesses

Premios y Reconocimientos

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Premio MEJOR PYME

2012

Premio Jóvenes Emprendedores – Empresa

de Base Tecnológica

Premio Redherring

2012

Premio Emtech 2011

ISCTE-IUL MIT-

Portugal Venture

Competition

Premio Emprendedores XXI

categoría CRECES XXI

Fondo Emprendedores de Repsol 2013

Premio Idea 2009

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6 tips: Learnt Lessons

CDTI is a real way of financing new start-up businesses or new business line of revenue.

Foster international exposure and proactively helps to find new partners all over the world or in any expertise domain.

Thanks to this AlphaSIP has interacted over 700 partners in 11 years of experience.

Support from technical experts from CDTI allow us to take part in large projects at a European and International level.

Our participation in large projects is a good opportunity to get in contact and take part in European Making Decisions Boards.

Timelines of R&D financed projects push your company to launch products to the market at a competitive time (without delays).

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www.alphasip.es

THANKSReliability Safety Efficiency

Madrid - Zaragoza - USA

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