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    CLOSED INTRAMEDULLARY

    INTERLOCKING NAILING

    FOR FEMORAL SHAFT FRACTUREMANAGEMENT

    Dr. SARDAR SOHAIL AFSAR,

    YEAR 4, POST GRADUATE TRAINEE,ORTHOPAEDIC UNIT, LRH, PESHAWAR.

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    Femur Fractures

    Common injury due to major violent trauma 1 femur fracture/ 10,000 people

    More common in people < 25 yr or >65 yr

    Femur fracture leads to reduced activity for107 days, the average length of hospital stay

    is 25 days

    Motor vehicle, motorcycle, auto-pedestrian,

    aircraft, and gunshot wound accidents aremost frequent causes

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    Anatomy Long tubular bone, anterior

    bow, flair at femoral condyles

    Blood supply

    Metaphyseal vessels

    Single nutrient artery in

    diaphysis enters through thelinea aspra

    Nutrient artery communicateswith medullary arteries inintramedullary canal

    Medullary arteries supply 2/3 ofendosteal blood supply

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    Blood Supply

    Reaming destroysintramedullary endosteal bloodsupply

    Periosteal blood flow increases

    Medullary blood supply is

    re-established over 8-12

    weeks if spaces left in

    canal by implant

    Unreamed intramedullarynailing decreases blood flowless; restoration of endostealblood flow earlier but equal toreamed canal at 12 weeks

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    Femur Fracture Classification

    AO/OTA Femur Diaphysis - Bone segment 32

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    Femur Fracture Management

    Piriformis fossa intact,

    lesser trochanter intact

    Can you nail this ?

    Should you nail this ?

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    Femur Fracture

    Management Initial traction with portable traction splint or

    transosseous pin and balanced suspension

    Evaluation of knee to determine pinplacement

    Timing of surgery is dependent on:

    Resuscitation of patient

    Other injuries - abdomen, chest, brain

    Isolated femur fracture

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    Hare traction splint for initial reduction of

    femur fractures prior to OR or skel

    etal

    traction

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    Diaphyseal fractures are managed by

    Intramedullary nailing.

    Proximal or distal 1/3 fractures MAY bemanaged best with a plate or an

    intramedullary nail depending on the location

    and morphology of the fracture

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    CLOSED INTRAMEDULLARY INTERLOCKING

    NAILING

    Effective method

    Preferred procedure

    Associated with high union rates and lowcomplication rates

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    HISTORY

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    Mid 1800s

    Ivory pegs were

    inserted into the

    medullary canal for

    non-union.

    It had been observed

    that ivory would get

    reabsorbed in thehuman bone.

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    1890

    Gluck recorded the first description of an

    interlocked intramedullary device.

    The device consisted of an ivory

    intramedullary nail that contained 2 holes at

    the end, through which ivory interlocking pins

    could be passed through.

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    WORLD WAR I

    Hey Groves of England reported the use of

    metallic rods for the treatment of gunshot

    wounds.

    Very high infection rate.

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    The Evolution of Kntscher Nailing

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    Gerhard Kntscher 1900-1972

    Gerhard Kntscher was born in Germany in

    1900.

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    Gerhard Kntscher - continued

    His early interest inintramedullary devices resulted

    from his work with the Smith-

    Petersen nail.

    Kntscher believed the same

    basic science principles would

    be able to be used for

    diaphyseal fractures.

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    Gerhard Kntscher - continued

    During development of his marrow nail he conducted

    studies on cadavers' and animals

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    Gerhard Kntscher - continued

    By late 1940s,

    Kntscher had

    designed a new nail,

    the cloverleaf nail.

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    Gerhard Kntscher - continued

    While there was some interest in the use of

    Kntschers technique in Europe during

    World War II, his method was essentially

    unknown in the US.

    This was until it was described in an article

    published in the March 12, 1945, TimeMagazine. Titled Amazing Thighbone

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    Medicine: Amazing Thighbone Monday, Mar. 12, 1945

    At England General Hospital in Atlantic City last week was a

    wounded soldier with a strangely mended femur (thighbone).The man had been treated by the Germans, his captors.

    When the broken bone failed to heal, after weeks of conventional treatment, the soldier was operated on.

    He was mystified to find that his only new wound was a 2-inch incision above the hipbone.

    Two days later, the German surgeons told him to move his

    leg; a few days after that, they told him to walk.

    He did and he has walked ever since.

    .

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    After his exchange, U.S. Army doctors X-rayed thesoldier's leg.

    They were amazed at what they saw: a half-inch metal rodof some kind had been rammed down the thighbonethrough the marrow for three-quarters of the bone's length,thus supplying a permanent, internal splint.

    Mechanically, the surgeons agree, there is no reason sucha splint should not work if the lower end of the rod werefirmly wedged in hard tissue.

    But in the past, use of internal splints has been restrictedto slim wire to align broken bones in fingers, toes andarms. In such cases, outside splinting is also used and themended bones are not required to withstand any end-to-end pressure.

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    They call the rod technique "a daring operation"

    and wonder how their German colleagues insert

    it without dangerously cutting down blood supplyand without introducing infection.

    Surgeons at the hospital cautiously say they"have no opinion one way or another about this

    case."

    But they add that they are not quite satisfied withthe way the bone is mending around the metal

    crutch, possibly because of impaired circulation.

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    1950s

    Two important techniques were developed.

    1. Intramedullary reamers

    2. Interlocking Screws

    Both techniques improved stability.

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    1950s Intramedullary reamers

    Flexible reamers were

    developed by

    Kntscher.

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    1960s Intramedullary nailingwent on hiatus in the

    1960s. Due to

    increased enthusiasm

    for compression plating

    of long bone fractures.

    Developments still

    continued with the

    cephalomedullary

    nails.

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    1960s continued

    The development of radiological image

    intensification,

    allowed surgeons to

    readopt closed nailingtechniques. With

    lower risks to surgeon

    and patient.

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    1970s and 1980s

    The exuberance that accompanied the

    advent of compression plating for tibias and

    femurs in the 1960s quickly diminished in the

    1970s.

    Thus renewed interest in refining closed

    nailing techniques appeared.

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    1990s and the 21st Century

    Introduction of new titanium nails,

    cephalomedullary devices such as the GSH

    (Green- Seligson-Henry) nail.

    Slotted cloverleaf designs were being

    replaced by non-slotted designs. Which

    provided greater torsional rigidity.

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    Future

    Two areas of future research.

    1. Biomaterials

    Biodegradable polymers

    Shape memory alloy

    2. Biological

    1. Bone morphogenic protein-2 and -7

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    PRESENT PRACTICE

    CLOSED ANTEGRADE INTRAMEDULLARY

    INTERLOCKING NAILING

    GOLD STANDART

    FOR FEMORAL SHAFT FRACTURE

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    Multiple choices

    Antegrade vs retrograde

    Via piriformis fossa vs trochanteric

    Supine position or lateral position

    With or without traction

    Reamed or unreamed

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    Several factors

    Fracture characteristic

    Associated musculoskeletal and/or visceral

    injuries

    Body habitus

    Associated local soft tissue injury

    Technical familiarity

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    INSERTION PORTAL

    ANTEGRADE NAILING Piriformis starting point

    Trochanteric starting point

    RETROGRADE NAILING

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    Antegrade nailing

    Piriformis starting point Healing rates as high as

    99% and low complication

    rates

    Colinear trajectory with

    long axis of femoral shaft

    Reduces the risk ofiatrogenic fracture

    communition and varus

    malalignment

    Relative technical difficulty

    esp. obese patients Also sensitive to

    anteroposterior translation-

    --hoop stresses

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    }

    Guide pin

    Degree of overlap indicates

    posterior position in piriformis fossa

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    Early antegrade nails designed for this

    starting point

    Based upon anatomy of proximal femur,posterior piriformis fossa is in line with

    proximal femoral canal

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    Subcutaneous location of greater trochantertechnically

    easier

    Risk of varus malalignment and iatrogenic fracture

    comminution

    Medially directed insertion angle---iatrogenic

    comminution

    So starting point not too lateral is crucial to avoid this

    Nail rotation by 900---- modification

    Implants specifically built--- proximal lateral bend

    This all has lead to reduced complication rates withresults similar to those seen with piriformis nailing

    Trochanteric starting point

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    TROCHANTERIC ENTRY

    Guide pin

    Need lateral image to judge anterior-

    posterior position

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    Retrograde nailing

    RELATIVE INDICATIONS

    Ipsilateral Fractures Femoral Neck

    Intertrochanteric

    Acetabular

    Tibia Patella

    Bilateral Femurs

    Polytrauma

    Obesity

    Pregnancy Distal Fractures

    Retrograde nailing hasadv. of

    improved fracturealignment of distalshaft fractures

    decreased operatingroom time

    decreased bloodloss

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    RETROGRADE ENTRY

    PCL

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    RETROGRADE NAILING Continued

    Alternative

    Insertion site in intracondylar notch at the apex of

    blumensaat line--- 1cm anterior to posterior

    cruciate ligament origin

    Distal end of nail must be buried beneath

    subchordral bone to avoid injury to patella with the

    knee in flexion

    At least two distal interlocks to minimize risk of

    secondary telescoping of nail into knee joint

    Retrograde nailing using modern techniques i.e.

    reaming, snug fitting nails, interlocking screws

    union rates similar to that of antegrade nailing

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    CONCERNS REGARDING RETROGRADE

    Cartilage Injury?

    Patello -femoral jointmechanics

    Nonunion and implantfailure with migration intoknee

    Intraarticular infection

    Nail removal

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    PATIENT POSITION

    Position--- supine

    Skin traction with foot

    secured in boot

    Non injured leg----hemilithotomy position

    Lateral decubitus ---

    improved ease ofaccess to piriformis

    fossa

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    BILATERAL FEMUR FRACTURES

    FREE LEG POSITION

    Supine

    Shortest set up time

    Easy Starting portal

    Ideal for Polytrauma +/-

    Bilateral

    **Need Extra Help***

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    REAMING

    Persistent subject of debate

    Systemic effects of reaming on multitraumapatient esp. with pulmonary injury

    Degree of fat embolization almost similar with reamed or unreamed nails

    Disrupted endosteal blood supplyreconstitutes rapidly

    Use nail 1 to 1.5 mm smaller then largestreamer used

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    REAMING Continued

    Avoid thermal necrosis and fat embolization Use of modern fluted reamer designs

    Sharp reamers

    Slower reamers produce less heat but more emboli

    then faster reaming

    Reaming has

    Beneficial effects on union rates Deposition of local bone graft

    Beneficial inflammatory response

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    REAMING Continued

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    NAIL INSERTION

    RETROGRADE

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    SPECIAL SITUATION

    Multitrauma patient

    Open fractures

    Vascular and neurological injury

    Obese

    Ipsilateral proximal femur and femoral shaft

    fractures

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    Multiple trauma

    Timing and safety of reaming

    Additional trauma of IM nail--- Borderline stable

    patient to decompensation cuz

    Release of inflammatory mediators

    Hypothermia

    Effects of reaming

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    Damage control orthopaedics

    Provisional surgical

    stabilization to minimizesurgical time, blood loss and

    additional trauma

    Usually with monolateral

    external fixator

    Converted to IM nailing

    Retrograde unreamed nailing

    with or without proximal

    interlocking--- alternative to

    external fixator

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    Open fractures

    Much less common then tibia

    Significant soft tissue trauma

    Timing of initial debridment does not significantly

    affect infection risk Severity of open injury most significant factor

    Wounds should be extended

    Nonviable soft tissues and bone should be debrided

    with serial debridment at 24 to 48 hoursrecommended

    Immediate IM nailing---- all but most severe cases

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    Provision external fixator

    useful Converted to IM nailing

    Intravenous antibiotics

    Gun shots causingfemoral fractures withentry and exit wound canbe treated as closefractures

    Extensive wounds ----treated as open fractures

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    Vascular and neurological injuries Rare and associated with penetrating trauma

    Algorithm for management

    Bony stabilization

    Neurovascular repair with attention to obtain proper length Usually external fixator

    Converted to IM nailing in 2 weeks

    Another option is retrograde IM nailing with interlocking

    deferred until vascular repair

    Reduces ischemic time and need for fasciotomy

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    Obese patient

    Starting point in antegrade nailing is problem

    Retrograde nailing --- good results

    Reduces surgery time and radiation exposure

    Antegrade

    Better results with trochanter insertion point rather then

    piriformis in obese patients esp. with new implants i.e.

    prox. Lateral bend

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    Ipsilateral proximal femur and femoral shaft

    fracture SOF fracture with NOF or intertrochanteric

    fracture--- challenging injuries

    In up to 9% of all SOF fractures

    Easily missed Do hip and knee radiology to all SOF fractures

    Variety of fixation techniques Separate implants

    Single IM device i.e. recon nail

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    COMPLICATIONS OF FEMORAL

    NAILING

    Malunion

    Nonunion

    Leg length discrepancy

    Infection

    Other potential complications

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    Malunion( angular and rotational) Angular malunion most common in prox. (30%)

    and distal (10%) fractures Blocking screws can be used

    Interference fit

    Diaphyseal angular malunion----in elderly patients

    with capacious canals Rotational malunion --- remain concern

    Alignment of anterior superior iliac spine, thepatella and the second toe

    Both legs should be examined for rotationalsymmetry

    CT is more accurate

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    Nonunion

    Less then 10%

    Deep infection should beconsidered

    Treatment

    Dynamization

    Exchange nail Plate fixation with bone

    grafting

    Fractures with bony

    defects, atrophic

    characteristics or faileddynamization

    Reaming with exchange

    nail or open graft and

    repair

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    Leg length discrepancy

    Obtaining equal lengths after nailing in

    comminuted fractures---- challenge(43% length

    discrepancy rates) Length should be compared immediately after

    nailing

    Post operative clinical examination or CT

    scanogram to define discrepancies

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    Infection

    Ranges from 1% to 3.8%

    Early (

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    Nail is removed

    Canal reamed for debridment purpose

    Nonviable bone resected Intravenous and potentially local antibiotics for at

    least 6 weeks

    Definitive reconst. delayed until the infection is

    controlled Monitoring

    Close clinical observation

    Complete blood count

    Erythrocyte sedimentation rate

    C-reactive protein levels

    Host factors

    Smoking and malnutrition should be addressed

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    Still concern for infection--- frozen tissue sections

    intraoperatively

    Other potential complications

    Heterotropic bone at site of antegrade nail

    insertion

    Neurovascular injury

    Prominent hardware

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    FUNCTIONAL OUTCOME

    May have functional residual deficit

    Reduced strength of hip abductors and

    extensors

    Altered gait patterns

    Needs prolonged muscle strengthening

    exercises

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    SUMMARY

    Effective method

    High union and low complication rates

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    Descriptive study

    On 68 patients in orthopaedic unit of ladyreading hospital, Peshawar

    From march 2002 to march 2004

    Patient age more then 15 years of each genderwith fracture shaft of femur due to high velocity

    gunshot injuries were included

    Patients with intertrochanteric, supracondylar

    fractures were excluded and also who failed tofollow up

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    All patients treated with either close or open

    interlocking nailing

    Out come was measured as poor, good and

    excellent

    Follow up for 18 months and in some cases

    for up to 30 months

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    64(94.12%) male and 4(5.88%) female

    64(94.12%) had close interlocking nailing while4(5.88%) had open interlocking nailing

    58(85.29%) had static and 10(14.71%) had dynamic

    interlocking nailing

    5(7.35%) had knee flexion contracture

    2(2.94%) had limb shortening of < 2cm

    4(5.88%) had non union

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    Excellent in 42(61.76%)

    Good in 18(26.4%)

    Poor in 8(11.77%)

    CONCLUSION

    So interlocking nailing is best option for treatment

    of fracture shaft of femur caused by high velocitygunshots

    ON GOING RESEARCH PROJECTS

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    ON GOING RESEARCH PROJECTS

    ON INTERLOCKING NAIL

    SIGN NAIL OPEN INTERLOCKING NAIL

    WITH OUT USE OF IMAGE INTENSIFIER

    COMPLICATIONS OF CLOSE ANTEGRADE

    INTRAMEDULLARY INTERLOCKING

    NAILING IN FEMORAL SHAFT FRACTURE

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    THANK YOU