diabliss - the world's first diabetic freindly cane sugar: introduction & product performance

7/22/2019 Diabliss - The world's first diabetic freindly cane sugar: Introduction & Product Performance

1/20

DIABLISSWORLDS FIRSTDIABETIC FRIENDLY CANE SUGAR:

INTRODUCTION & PRODUCTPERFORMANCE


2/20

Summary

For the first time in the world DiaBliss has been successful in making cane sugar

diabetic friendly by blending with a herbal extract rich in anti-oxidants,

nutrients and therapeutic agents

DiaBliss Sugar provides unlimited food choices for diabetics, pre-diabetics and

wellness solutions for entire family.

DiaBliss Herbal Solution is colorless, odorless and tasteless thereby allowing high

degree of versatility in formulations and for delivery of health & wellness to

various segments of population

DiaBliss Sugar is a drop in replacement to normal cane sugar and can be used

wherever sugar is used. DiaBliss tested and developed over 20 products todate spanning all categories of food including prepared foods, beverages,

chocolates, sweets, baked goods.

DiaBliss Sugar has been extensively tested and found to be safe for human

consumption. Hundreds of diabetics ranging in age from 8 to 82 (type 1, type

2) have consumed DiaBliss Sugar for periods ranging from 3 months to 4 yearswith HbA1c, Fasting and PP levels showing lowering trends


3/20

Diabetes Mellitus

Diabetes (diabetes mellitus) is classified as a

metabolism disorder

Types of diabetesType 1, Type 2 & Gestational

Diabetes (i.e. during pregnancy). 80% of diabeticpopulation is type 2.

In diabetics the body either does not produce

enough insulin, produces no insulin (Type 1), or hascells that do not respond properly to the insulin the

pancreas produces (type 2).

Diabetes effects almost every organ in the body

3


4/20

Diabetes A global Epidemic

IndiaDiabetic

Capital of the

world!

A global epidemicwith significant

growth rates of

diabetes projected.

Diabetes ratesexpected to double

world wide in next

20 years

Asia Diabetics % Diabetic North America Diabetics % DiabeticIndia 85,923,733 7.1% United States 38,818,308 12.3%

China 60,931,800 4.5% Mexico 11,345,990 10.1%

Pakistan 13,882,616 7.6% Canada 4,066,503 11.6%

Indonesia 10,931,501 4.6% Puerto Rico 459,630 12.4%

Bangladesh 9,303,599 6.1%

Japan 9,297,280 7.3%

Philippines 6,186,636 6.7% Europe Diabetics % Diabetic

Korea, Republic of 5,354,958 9.0% Germany 9,839,160 12.0%

Thailand 5,076,322 7.7% France 6,166,870 9.4%Malaysia 3,232,940 10.9% Turkey 5,596,426 7.4%

Viet Nam 2,574,620 2.9% Italy 5,235,959 8.8%

Spain 4,112,083 8.7%

Middle East Diabetics % Diabetic Poland 3,583,642 9.3%

Iran 4,714,873 6.1% United Kingdom 3,095,907 4.9%

Saudi Arabia 3,970,642 13.6% Argentina 2,695,740 6.0%

Iraq 2,599,740 7.8% Romania 1,599,676 8.4%

Morocco 2,497,580 7.6% Portugal 1,309,710 12.4%

Syrian Arab Re publ ic 1,828,988 8.3% Netherl ands 1,291,968 7.7%

Afghanistan 1,683,007 6.6% Greece 951,737 8.8%

United Arab Emirates 1,008,217 12.2% Austria 950,713 11.2%

Tunisia 916,088 8.5% Czech Republic 914,903 8.7%

Yemen 613,175 2.5%

Israel 567,510 7.1% South America Diabetics % Diabetic

Jordan 471,068 7.5% Brazil 14,258,480 6.0%

Kuwait 386,862 10.8% Colombia 2,255,424 4.8%

Lebanon 332,948 7.7% Venezuela 1,707,820 5.9%

Oman 307,856 11.1% Peru 1,706,608 5.6%

Qatar 254,976 13.3% Cuba 1,228,033 11.0%

Bahrain 177,778 14.4% Guatemala 1,065,248 6.9%

4


5/20

Diabetic Prevalence Rates in IndiaUrban vs. Rural

Metro cities diabetes prevalence rates is approximately 15%, with pre diabetics constituting

another 15% of the population. Target market in urban India is therefore 30%!

Rural India has significantly lower Diabetes prevalence rates due to lifestyle factors & also

due to poor detection

5


6/20

What is DiaBliss?

For the first time in the world we are able to render pure cane sugar diabetic

friendly:

DiaBliss is coming to you after 10 years of R&D and 4 years of product

performance testing among100s of diabetics

A colorless, odorless and tasteless herbal solution is extracted from 7-17 spicesincluding Turmeric, Black Pepper, Cinnamon, Ginger, Fenugreek, Gooseberry,

Pomegranate by using only water and no other chemicals or solvents .

DiaBliss system has limitless versatility: The herbal solution is blended with sugar

makes sugar diabetic friendly and allows glucose present in the blood stream to be

effectively absorbed by the body at a cellular level. The solution when blendedwith rice renders carbohydrates diabetic friendly. Along the same lines, fruit based

foods and beverages have been blended with herbal solution to render them

diabetic friendly.

DiaBliss developed over 20 products which are being launched into retail FMCG

applications in a phased manner.

6


7/20

DiaBliss Herbal Solution

Active Ingredients

Herbal solution contains a variety of active phytochemicals, including the

flavonoids, terpenoids, lignans, sulfides, polyphenolics, carotenoids, coumarins,

saponins, plant sterols, curcumins, and pthalides.

Many of these herbs contain potent antioxidant compounds that provide

significant protection against chronic diseases. These compounds are known to have variety of health & wellness

characteristics - LDL cholesterol from oxidation, inhibit cyclooxygenase andlipoxygenase enzymes, improved metabolism, enhance insulin sensitivity, inhibit

lipid peroxidation, or have antiviral or antitumor activity.

7

Fenugreek

TurmericBlack Pepper

GingerCinnamon

GooseberryPomagranate


8/20

Competitive Positioning Sweeteners vs. DiaBliss

8

Product Brand Names Composition/

Chemical Name

Manufacturing Process Taste Factors & Cooking Solutions Health Effects Calorific Value

Aspertame Equal, Nutra

Sweet

N-L-aaspartyl-L-

phenylalanine-l-methyl

ester (APM)

Fermentation and sysnthesis with

methanol with metal catalysts

Interacts with some f oods and cannot

perfectly replace sugar, not thermally

stable; Bitter after taste.

Aspartame must be avoided by people

with the genetic condition

phenylketonuria(PKU); Recent

packaging indicates not recommended

for children.

4 calories per

gram; 180 times

sweeter than

sugar

Sucralose Splenda,

Sugar Free

4-chloro-4-deoxy-.alpha.-

D-galactopyranosyl 1.6-

dichloro-1.6-dideoxy-

.beta.-D-fructo-

furanoside

Five Step Chemical Process

including chlorination of sucrose,

followed by high temperature, low

pH process for final conversion to

sucralose

There is still a distinct chemical taste

especially when products are used to

make sweets. Thermally stable and can

be used in almost all categories of foods &

beverages.

FDA & WHO evaluated over 100 studies

over 20 years and concluded the product

is generally safe. Short term studies

indicated 10-15% accumulating in the

body.

No calorific

content

Saccharin Sweet' n Low,

Sweet Twin, and

Necta Sweet

2H-16,2-benzothiazol-

1,1,3-trione

Two chemical synthesis processes Bitter after taste. Not thermally stable. Suspected Carcinogen (bladder cancer). 1 calorie per

gram, 10x

sweeter

Stevia Truvia, PureVia,

SweetLeaf

Sweetening ingredient -

Steviol glycosides. Class

of Compaounds found in

Stevia plant leaf.

Minimal Processing for dark

colored stevia extracts. Crystalline

forms involves some level of

chemcal processing

Bitter after taste; Can be used for cooking

and baking

Approved by FDA; Banned in some

European countries

4 calories per

gram; 200-400

times sweeter

than sugar

Levulose Dezire D-Frustose Residual after taste for a long time; Can

be used for cooking and baking; Indiansweets have a distinct after taste

Fructose based productuct. A lot of

literature on impact of fructose onobesity and type 2 diabetes.

4 calories per

gram; LowerGlycemic Index

than Sugar

Herbal Cane Sugar DiaBliss Cane Sugar blended with

herbal extracts

A colourless, tasteless and

odourless extract from 7 common

herbs and spices; Only water used

in preparation of herbal solution.

Only product that can claim exact same

taste of sugar; Thermally stable and can be

used in all categories of foods similar to

Sucralose.

HbA1c, Fasting and Post Pradial levels

show decreasing trends; Analysis and

animal studies indicate product is safe

for human consumption

4 calories per

gram; Lower

Glycemic Index

than Sugar


9/20

Overall Process

Water based

extraction ofmolecular values

Herbs & Spices

Herbal Extract

Herbal

SolutionBlending

Ageing/

DryingPackaging

Sugar

(or Salt, Rice)

Primary Products

DiaBliss Sugar

DiaBliss Salt

DiaBliss Rice

HerbalSolution

Blending Processing Packaging

Ingredients

Derivative Products

DiaBliss Beverages(Lemon Tea, Lemon Juice, Instant Tea & Coffee Mix)

DiaBliss Prepared Foods ( Mixed Fruit Jam, Ketchup, Indian Sweet Mixes, etc)

DiaBliss Cereals (Multigrain Porridge)DiaBliss Chocolates (Dark, Milk & Filled)DiaBliss Ice Cream Mixes (Vanilla, Mango)

Institutional Products(Bulk Packaging of DiaBliss Sugar & other products)

Sweet Chains

BakeriesHotels & Institutional

Food Companies

Beverage Companies

9


10/20

DiaBliss Phase 1 FMCG Products(Chennai, Hyderabad & Bangalore Soft Launch)

10

DiaBliss Herbal Sugar Standy Pouch, 500g DiaBliss Herbal Sugar Sachet Box, 30x5g

DiaBliss Mixed Fruit Jam, 200g

DiaBliss Iodised Herbal Salt, 1 kg

(July 2013 Launch)

DiaBliss Lemon Tea Sachet Box, 30x10g


11/20

Product Performance Summary

Product Characterization @ SGS

labs, Chennai

Trials @ Sugen Life Sciences,

Tirupati

Acute & Sub-Acute Toxicity studies

Summary of Product Usage &

Customer Testimonials

Short Term Trials

Long Term Trials

Product composition is safe for humanconsumption based on heavy metals & pesticide

analyses.

No detrimental impact on animals health

parameters. Histopathological studies indicated

no organ impact when subject to acceleratedusage of product

GTT data indicates DiaBliss Sugar can be

classified as low glycemic index product

Extended GTT results with diabetic subjectsindicated excellent blood sugar control even with

high loading of DiaBliss sugar.

Data from diabetics who consumed product for

periods between 3 months to 36 months indicates

product is providing significant health benefits to

diabetics

11


12/20

Acute Oral Toxicity with Wistar Rats


13/20

Sub-Acute Oral Toxicity with Wistar Rats


14/20

DiaBliss - Low Glycemic Index Sugar14

DiaBliss Sugar - Low Glycemic Index Food (GI = 53 vs. 60-65 for normal sugar & 100 for glucose)

11-20% decrease in GI can explain part of the observation that consumers do not see increase in

blood sugar when they consume DiaBliss Sugar

Normalised average blood sugar values of diabetic subjects shows similar GI behavior of Diabliss

sugar on blood sugar profiles


15/20

DiaBliss Sugar Excellent Short Term Absorption of

Blood Glucose

For over 70% of diabetics in this trial, blood sugar levels have come down to below fasting levels

within 3 hours of consuming DiaBliss Herbal Sugar indicating excellent absorption characteristics ofDiabliss Sugar. NOTE: Each diabetic consumed 50g of Dibliss Sugar (8times the daily consumption

levels for diabetics)

Glycosuria analysis between regular sugar and Diabliss sugar consumption for subject 6 shows safetytrigger mechanism of glucose excretion through urine not triggered with Diabliss sugar

15

SubjectNumber Fasting 60 min 120 min 180 min

1 Nil + Trace Nil

2 Nil Trace Nil Nil

3 Trace ++ + Trace

4 Nil + Nil Nil

5 Nil Trace + Nil

6 (Regular Sugar) Nil ++ + Nil

6 (DiaBliss Sugar) Nil Trace Trace Nil

7 Nil Trace Nil Nil

8 Nil + Trace

Urine Analysis

Note:

Reading

Trace

+

++

+++

++++ 1,500-2,000 mg/dl

500-1,000 mg/dl

250-500 mg/dl

Up to 250 mg/dl

Urine Glucose (Glycosuria)

1,000-1,500 mg/dl


16/20

Excellent Long Term Safety & Blood Sugar

Levels HbA1c

Excellenperf

ormance in

type 1 &

type 2

diabetics:

Type 1

30-45%

lower

HbA1c

Type 2

diabetics10-

20%

lower

HbA1c

16


17/20

Long Term Efficacy Type 1 Diabetic ExampleFasting, PP & HbA1c Levels

Type 1 diabetic, Age 58

9 months on DiaBliss Herbal cane sugar

40% reduction in HbA1c

0

50

100

150

200

250

4/3/2012 14/8/2012 15/9/2012 17/9/2012

BloodSugarLevels,mg/dl

Type 1 Diabetic, Female, age 58 - Fasting & PP Profiles

Fasting

PP

Started consuming DiaBliss Herbal Cane Sugar

for Tea & Coffee

6

6.5

7

7.5

8

8.5

9

4/3/2012 6/6/2012 14/8/2012 17/9/2012

HbA1c

Type 1 Diabetic, Female, age 58 - HbA1c Profile

Started consuming DiaBliss

Herbal Cane Sugar for

Tea & Coffee

* Blood Sugar levels measured at Mohan Diagnostics, Madurai

17

Subject underwent

Fistula Operation


18/20

Long Term Efficacy Type 1 Juvenile DiabeticHbA1c Levels

8 year old juvenilediabetic

Two years on

DiaBliss Sugar

Major lifestyle

improvement Able to go to

school full-time

Able to enjoy all

kinds of foods &

sweets

Gaining body

weight without

significant increase

in insulin dosage

45% reduction in

HbA1c levels* Blood Sugar levels measured at Priya Diagnostics, Besant Nagar, Chennai

18


19/20

Long Term Efficacy Type 2 Diabetic ExampleFasting, PP & HbA1c Levels

Type 2 Diabetic, Age 63

18 months on DiaBliss herbal cane sugar

Lowered medication by 50%; Stabilized Fasting, PP & HbA1c swings

* Blood Sugar levels measured at Hi Tech Labs, Vadapalani, Chennai & Precision Labs, Adyar, Chennai

19


20/20

THANK YOUDiaBliss Contacts:

www.diabliss.com

20

VR. Ramanathan, [email protected]

Tel: +91-9840427966

Siva Vallabhaneni, COO

[email protected]: +91-7760980631

diabliss - the world's first diabetic freindly cane sugar: introduction & product performance

Documents