dissolution media preparator dissolution media preparator Ÿ enables filtration, pre-heating,...
TRANSCRIPT
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Dissolution Media PreparatorŸ Enables filtration, pre-heating, deaeration,
and precise dosing of media in the vessel within the dissolution bath
Ÿ 21 ltr media tank capacity allows filling of dissolution vessels for up to 3 dissolution tests (n = 6)
Ÿ Batch degassing ensures inter-vessel degassing consistency
Ÿ Volumetric dispensing with an accuracy better than + 1% as per USP, FDA and Ph. Eur. requirements
Ÿ Special nozzle design allows the handling of surfactant and frothing media like Sodium Lauryl Sulphate (SLS)
Ÿ Programmable deaeration time, temperature and vacuum for effective deaeration of different media
Ÿ Maintains media under vacuum at desired temperature while in idle condition
Ÿ Virtually zero dead volume minimizes wastage of media
Ÿ Programmable dispensing volumes from 200 ml to 4 ltrs
Ÿ Fast filling of dissolution vessels at a dispensing rate of 900 ml/min
Ÿ Programmable rinse and cleaning cycle allows the instrument to run through a prevalidated self cleaning procedure
Ÿ On-board memory stores 10 batch information of degassed media
QbDQuality by Design
Ÿ Unparalleled versatility due to 1 ml volume change increments
oŸ 360 turning radius allows it to be
maneuvered in tight placesŸ Multifunction single hose for dispensing,
aspirating, cleaning, rinsing, and draining ensures no lifting of heavy media tanks
Versatility
Ÿ Ergonomically designed nozzle with embedded dispense switch for ease of operation
Ÿ User friendly validation and calibration of media volumes
User friendly
Ÿ Print out of validation, calibration, dispensed volume and temperature reports
Reports
360 turningradius°
CIPClean-In-Place No lifting of
media tankVolume change
increment
1ml
Media volume
21 Ltr.
Frothy mediahandled
Dead volume
0Virtually
Programmablevacuum
EMP-21
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The information contained in this document is believed to be correct, But E LECTROLAB accepts no liability for any errors and reserves the right to alter specifications without notice
• Complete range of Dissolution Testers • Disintegration Testers • Friability Testers• Tablet Hardness Testers • Tap Density Testers • Electromagnetic Sieve Shaker • Powder Flow Tester
Specifications
Our Products
Certified ISO 9001 : 2008
< 6 ppm is recommended dissolved oxygen level for USP Prednisone Tablets RS (Ref : USP Dissolution Toolkit version 2.0)
USP 35 states “Dissolved gases can cause bubbles to form, which may change the results of the test.”
Importance of Degassing
2 to 21 litres
± 1%
900 ml/min
0.2 to 4 litres
± 1%
900 ml/min
o o 20 C to 50 Co0.5 C
Accuracy
Aspiration :
Media volume
Flow rate (during run cycle)
Dispense :
Dispense volume
Temperature :
Temperature range
Accuracy
Flow rate (during run cycle)
Temperature accuracy
100 kg
Stainless Steel
100 to 500 mm/Hg
High performance piston pump
230 VAC/50 Hz 10%110 VAC/50 Hz ± 10%
±
55 x 92 cm cm
± 1%Piston pump accuracy
Degassing level (measured by DO meter)2
Media tank
Vacuum
Piston pump
Electrical power
Dimensions (Ø x H)
Weight
Model EMP-21
Other specifications :
Inter & Intra Laboratory
VariabilityReliability
Ÿ 52.3% of mean percent dissolved Ÿ 11.8% of standard deviation
Effective deaeration reduces variability in results by:
Ref : Eaton J et al. Perturbation Study of Dissolution Apparatus Variables -A Design of Experiment Approach. Dissolution Technologies;14(2):20-26.
* Dependent on media type and conditions
CE
Optional Accessory : Optical DO meter2
< 5 ppm of *DO2
ELECTROLAB
&Service
Worldwide
SalesHead Office:
401, Tirupati Udyog, I. B. Patel road, Off. Western Express Highway, Goregaon (East), Mumbai- 400063, India.
Tel: +91-22-40413131 Fax: +91-22-40413199, Website : www.electrolabindia.com, Email : [email protected]
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