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Page 1: PARTNERSHIP FOR RESEARCH AND EDUCATION IN MATERIALS NSF/DMR 0934212

New Mexico Highlands UniversityMorehouse College

Georgia Institute of TechnologyLight-Matter Interactions: Theory and Applications (LMITA)

PARTNERSHIP FOR RESEARCH AND EDUCATION IN MATERIALS NSF/DMR 0934212

The general goal of LMITA Thrust 1 to find efficient synthetic route to obtain E,E-3,5-bis(thienylidene)piperid-4-ones with donor substituents, that will be tested as materials for photodynamic therapy as photosensitizer.

Photodynamic therapy (PDT) combines a drug (called a photosensitizer) with a specific type of light to kill cancer cells.

Undergraduate student Rachel Lucero and graduate student Evgenia Leonova working on the synthetic project under supervision of Professors Timofeeva and Martinez.

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0

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1400 R=CH

3, R

1=NMe

2, n=1

R=CH3, R

1=NEt

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R=H, R1=NMe

2, n=1

TP

A C

ros

s S

ec

tio

n (

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-50c

m4s

/ph

oto

n)

Excitation Wavelength (nm)

Two Double Bonds

Graph demonstrating significant two-photon activity of synthesized molecules with a long chain of conjugation.

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