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C:\Users\Admin\Desktop\Dr_michael_mullan_sarasota_publications.txt Tuesday, September 04, 2012 9:00 PM

Publications By Dr. Michael Mullan

President and CEO of Roskamp Institute, Sarasota, FL

1.

2012

Sean Kennelly; Laila Abdullah; Rose Anne Kenny; Venkat Mathura; Cheryl A Luis; Benoit Mouzon;

Fiona Crawford; Michael Mullan ; Brian Lawlor

Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the

antihypertensive nilvadipine in Alzheimer's patients--an open-label trial.

International journal of geriatric psychiatry 2012;27(4):415-22.

2.

2011

Laila Abdullah; Gogce Crynen; Jon Reed; Alex Bishop; John Phillips; Scott Ferguson; Benoit

Mouzon; Myles Michael Mullan ; Venkatarajan Mathura; Michael Mullan ; et al.

Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents.

Neuromolecular medicine 2011;13(4):275-88.

3.

2011

Daniel Paris; David Beaulieu-Abdelahad; Corbin Bachmeier; Jon Reed; Ghania Ait-Ghezala; Alex

Bishop; Jin Chao; Venkat Mathura; Fiona Crawford; Michael Mullan

Anatabine lowers Alzheimer's Aß production in vitro and in vivo.

European journal of pharmacology 2011;670(2-3):384-91.

4.

2011

S P Kennelly; L Abdullah; D Paris; J Parish; V Mathura; M Michael Mullan ; F Crawford; B A

Lawlor; R A Kenny

Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug

Nilvadipine: results from a 6-week open label study.


5.

2011

Corbin J Bachmeier; David Beaulieu-Abdelahad; Michael J Michael Mullan ; Daniel Paris

Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro

model of the blood-brain barrier.

Microcirculation (New York, N.Y. : 1994) 2011;18(5):373-9.

6.

2011

Corbin Bachmeier; David Beaulieu-Abdelahad; Michael Mullan ; Daniel Paris

Selective dihydropyiridine compounds facilitate the clearance of ß-amyloid across the

blood-brain barrier.


7.

2011

Corbin J Bachmeier; David Beaulieu-Abdelahad; Nowell J Ganey; Michael J Michael Mullan ; Gary M

Levin

Induction of drug efflux protein expression by venlafaxine but not desvenlafaxine.

Biopharmaceutics & drug disposition 2011;32(4):233-44.

8.

2011

Daniel Paris; Corbin Bachmeier; Nikunj Patel; Amita Quadros; Claude-Henry Volmar; Vincent

Laporte; Jim Ganey; David Beaulieu-Abdelahad; Ghania Ait-Ghezala; Fiona Crawford; et al.

Selective antihypertensive dihydropyridines lower Aß accumulation by targeting both the

production and the clearance of Aß across the blood-brain barrier.

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Molecular medicine (Cambridge, Mass.) 2011;17(3-4):149-62.

9.

2011

Pancham Bakshi; Elaina Margenthaler; Jon Reed; Fiona Crawford; Michael Mullan

Depletion of CXCR2 inhibits ?-secretase activity and amyloid-ß production in a murine model of

Alzheimer's disease.

Cytokine 2011;53(2):163-9.

10.

2011

Daniel Paris; Venkat Mathura; Ghania Ait-Ghezala; David Beaulieu-Abdelahad; Nikunj Patel;

Corbin Bachmeier; Michael Mullan

Flavonoids lower Alzheimer's Aß production via an NF?B dependent mechanism.

Bioinformation 2011;6(6):229-36.

11.

2011

Cheryl A Luis; Laila Abdullah; Ghania Ait-Ghezala; Benoit Mouzon; Andrew P Keegan; Fiona

Crawford; Michael Mullan

Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum ß-Amyloid.

International journal of Alzheimer's disease 2011;2011():786264.

12.

2010

Corbin Bachmeier; Michael Mullan ; Daniel Paris

Characterization and use of human brain microvascular endothelial cells to examine ß-amyloid

exchange in the blood-brain barrier.

Cytotechnology 2010;62(6):519-29.

13.

2010

Daniel Paris; Nowel Ganey; Magdalena Banasiak; Vincent Laporte; Nikunj Patel; Myles Michael

Mullan ; Susan F Murphy; Gi-Taek Yee; Corbin Bachmeier; Christopher Ganey; et al.

Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's

disease.

The Journal of neuroscience : the official journal of the Society for Neuroscience

2010;30(34):11251-8.

14.

2010

S Ferguson; B Mouzon; G Kayihan; M Wood; F Poon; S Doore; V Mathura; J Humphrey; B O'Steen; R

Hayes; et al.

Apolipoprotein E genotype and oxidative stress response to traumatic brain injury.

Neuroscience 2010;168(3):811-9.

15.

2010

Daniel Paris; Nowell J Ganey; Vincent Laporte; Nikunj S Patel; David Beaulieu-Abdelahad; Corbin

Bachmeier; Amelia March; Ghania Ait-Ghezala; Michael J Michael Mullan

Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's

disease.

Journal of neuroinflammation 2010;7():17.

16.

2010

Nikunj S Patel; Venkatarajan S Mathura; Corbin Bachmeier; David Beaulieu-Abdelahad; Vincent

Laporte; Ophelia Weeks; Michael Mullan ; Daniel Paris

Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling

via direct interaction with VEGFR-2.

Journal of neurochemistry 2010;112(1):66-76.

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17.

2010

Venkatarajan S Mathura; Nikunj Patel; Corbin Bachmeier; Michael Mullan ; Daniel Paris

A 3D-QSAR model based screen for dihydropyridine-like compound library to identify inhibitors

of amyloid beta (Aß) production.


18.

2009

Pancham Bakshi; Chao Jin; Pierre Broutin; Beniam Berhane; Jon Reed; Michael Mullan

Structural optimization of a CXCR2-directed antagonist that indirectly inhibits gamma-secretase

and reduces Abeta.

Bioorganic & medicinal chemistry 2009;17(23):8102-12.

19.

2009

Laila Abdullah; Cheryl Luis; Daniel Paris; Benoit Mouzon; Ghania Ait-Ghezala; Andrew P Keegan;

Duolao Wang; Fiona Crawford; Michael Mullan

Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease

in an ADAPT subcohort.


20.

2009

Claude-Henry Volmar; Ghania Ait-Ghezala; Jeremy Frieling; Ophelia I Weeks; Michael J Michael

Mullan

CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity

independently of tumor necrosis factor receptor associated factor (TRAF) signaling.

Experimental cell research 2009;315(13):2265-74.

21.

2009

F Crawford; M Wood; S Ferguson; V Mathura; P Gupta; J Humphrey; B Mouzon; V Laporte; E

Margenthaler; B O'Steen; et al.

Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury.

Neuroscience 2009;159(4):1349-62.

22.

2009

Cheryl A Luis; Laila Abdullah; Daniel Paris; Amita Quadros; Myles Michael Mullan ; Benoit

Mouzon; Ghania Ait-Ghezala; Fiona Crawford; Michael Mullan

Serum beta-amyloid correlates with neuropsychological impairment.

Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

2009;16(2):203-18.

23.

2009

Laila Abdullah; Cheryl Luis; Daniel Paris; Ghania Ait-ghezala; Benoit Mouzon; Elizabeth Allen;

Julia Parrish; Myles A Michael Mullan ; Scott Ferguson; Marcie Wood; et al.

High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease

patients.


24.

2009

Cheryl A Luis; Andrew P Keegan; Michael Mullan

Cross validation of the Montreal Cognitive Assessment in community dwelling older adults

residing in the Southeastern US.


25.

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2009

Venkatarajan S Mathura; Daniel Paris; Michael J Michael Mullan

A novel physico-chemical property based model for studying the effects of mutation on the

aggregation of peptides.

Protein and peptide letters 2009;16(8):991-8.

26.

2008

Pancham Bakshi; Elaina Margenthaler; Vincent Laporte; Fiona Crawford; Michael Mullan

Novel role of CXCR2 in regulation of gamma-secretase activity.

ACS chemical biology 2008;3(12):777-89.

27.

2008

Ghania Ait-ghezala; Laila Abdullah; Claude-Henry Volmar; Daniel Paris; Cheryl A Luis; Amita

Quadros; Benoit Mouzon; Myles A Michael Mullan ; Andrew P Keegan; Julia Parrish; et al.

Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's

disease.

Cytokine 2008;44(2):283-7.

28.

2008

Vincent Laporte; Ghania Ait-Ghezala; Claude-Henry Volmar; Christopher Ganey; Nowell Ganey;

Marcie Wood; Michael Mullan

CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice.

Brain research 2008;1231():132-42.

29.

2008

Michael J Michael Mullan ; Hanna Magowan; Colin D Weir

Femoral artery necrosis due to parenteral intravascular drug misuse: a case report and

literature review.

The Ulster medical journal 2008;77(3):203-4.

30.

2008

Barbara K Martin; Christine Szekely; Jason Brandt; Steven Piantadosi; John C S Breitner;

Suzanne Craft; Denis Evans; Robert Green; Michael Mullan

Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial

(ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.

Archives of neurology 2008;65(7):896-905.

31.

2008

Claude-Henry Volmar; Ghania Ait-Ghezala; Jeremy Frieling; Daniel Paris; Michael J Michael Mullan

The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta)

production.

Cytokine 2008;42(3):336-44.

32.

2008

Nikunj S Patel; Amita Quadros; Steven Brem; Marguerite Wotoczek-Obadia; Venkatarajan S Mathura;

Vincent Laporte; Michael Mullan ; Daniel Paris

Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide.

Amyloid : the international journal of experimental and clinical investigation : the official

journal of the International Society of Amyloidosis 2008;15(1):5-19.

33.

2008

Michael J Michael Mullan ; Julie L Scoffield; Pawan K Rajpal

Appendicectomy complicated by Addisons disease.

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The Ulster medical journal 2008;77(1):58-9.

34.

2007

Fiona C Crawford; Marcie Wood; Scott Ferguson; Venkatarajan S Mathura; Brandon Faza; Sarah

Wilson; Tao Fan; Barbara O'Steen; Ghania Ait-Ghezala; Ronald Hayes; et al.

Genomic analysis of response to traumatic brain injury in a mouse model of Alzheimer's disease

(APPsw).

Brain research 2007;1185():45-58.

35.

2007

Laila Abdullah; Daniel Paris; Cheryl Luis; Amita Quadros; Julia Parrish; Luis Valdes; Andrew P

Keegan; Venkatarajan Mathura; Fiona Crawford; Michael Mullan

The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels.

Neuroscience letters 2007;428(2-3):53-8.

36.

2007

Daniel Paris; Nikunj Patel; Amita Quadros; Monica Linan; Pancham Bakshi; Ghania Ait-Ghezala;

Michael Mullan

Inhibition of Abeta production by NF-kappaB inhibitors.

Neuroscience letters 2007;415(1):11-6.

37.

2007

Ghania Ait-Ghezala; Claude-Henry Volmar; Jeremy Frieling; Daniel Paris; Miles Tweed; Pancham

Bakshi; Michael Mullan

CD40 promotion of amyloid beta production occurs via the NF-kappaB pathway.

The European journal of neuroscience 2007;25(6):1685-95.

38.

2007

H Fai Poon; Laila Abdullah; Myles A Michael Mullan ; Michael J Michael Mullan ; Fiona C Crawford

Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells.

Neurochemistry international 2007;50(1):69-73.

39.

2007

Timothy A Crowell; Cheryl A Luis; David E Cox; Michael Mullan

Neuropsychological comparison of Alzheimer's disease and dementia with lewy bodies.

Dementia and geriatric cognitive disorders 2007;23(2):120-5.

40.

2007

H Fai Poon; Laila Abdullah; Jon Reed; Sarah M Doore; Cyndi Laird; Venkat Mathura; Michael

Mullan ; Fiona Crawford

Improving image analysis in 2DGE-based redox proteomics by labeling protein carbonyl with

fluorescent hydroxylamine.

Biological procedures online 2007;9():65-72.

41.

2007

Venkatarajan S Mathura; Mahendiranath Rangareddy; Pankaj Gupta; Michael Mullan

CliniProteus: A flexible clinical trials information management system.


42.

2006

Fiona C Crawford; Marcie L Wood; Sarah E Wilson; Venkatarajan S Mathura; Tyler R Hollen; Freya

Geall; Deepak N Kolippakkam; Michael J Michael Mullan

Cocaine induced inflammatory response in human neuronal progenitor cells.

-5-


Journal of neurochemistry 2006;97(3):662-74.

43.

2006

Laila Abdullah; Ghania Ait-Ghezala; Fiona Crawford; Timothy A Crowell; Warren W Barker; Ranjan

Duara; Michael Mullan

The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease.


44.

2006

Timothy A Crowell; Juno Paramadevan; Laila Abdullah; Michael Mullan

Beneficial effect of cholinesterase inhibitor medications on recognition memory performance in

mild to moderate Alzheimer's disease: preliminary findings.

Journal of geriatric psychiatry and neurology 2006;19(1):13-5.

45.

2006

Vincent Laporte; Ghania Ait-Ghezala; Claude-Henry Volmar; Michael Mullan

CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models.

Journal of neuroinflammation 2006;3():3.

46.

2006

Amy R Borenstein; James A Mortimer; Yougui Wu; Fern M Jureidini-Webb; M Daniele Fallin; Brent J

Small; Michael Mullan ; Fiona C Crawford

Apolipoprotein E and cognition in community-based samples of African Americans and Caucasians.

Ethnicity & disease 2006;16(1):9-15.

47.

2005

Ghania Ait-Ghezala; Venkatarajan S Mathura; Vincent Laporte; Amita Quadros; Daniel Paris;

Nikunj Patel; Claude-Henry Volmar; Deepak Kolippakkam; Fiona Crawford; Mike Michael Mullan

Genomic regulation after CD40 stimulation in microglia: relevance to Alzheimer's disease.

Brain research. Molecular brain research 2005;140(1-2):73-85.

48.

2005

Venkatarajan S Mathura; Daniel Paris; Ghania Ait-Ghezala; Amita Quadros; Nikunj S Patel; Deepak

N Kolippakkam; Claude-Henry Volmar; Michael J Michael Mullan

Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein.

Biochemical and biophysical research communications 2005;332(2):585-92.

49.

2005

Daniel Paris; Ghania Ait-Ghezala; Venkatarajan S Mathura; Nikunj Patel; Amita Quadros; Vincent

Laporte; Mike Michael Mullan

Anti-angiogenic activity of the mutant Dutch A(beta) peptide on human brain microvascular

endothelial cells.

Brain research. Molecular brain research 2005;136(1-2):212-30.

50.

2005

Daniel Paris; Amita Quadros; Nikunj Patel; Anthony DelleDonne; James Humphrey; Michael Mullan

Inhibition of angiogenesis and tumor growth by beta and gamma-secretase inhibitors.

European journal of pharmacology 2005;514(1):1-15.

51.

2005

Terrence Town; Jun Tan; Richard A Flavell; Mike Michael Mullan

T-cells in Alzheimer's disease.

Neuromolecular medicine 2005;7(3):255-64.

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52.

2004

Dylan G Harwood; Warren W Barker; Raymond L Ownby; Michael Mullan ; Ranjan Duara

No association between subjective memory complaints and apolipoprotein E genotype in

cognitively intact elderly.


53.

2004

Dylan G Harwood; Warren W Barker; Raymond L Ownby; Peter St George-Hyslop; Michael Mullan ;

Ranjan Duara

Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample.

International psychogeriatrics / IPA 2004;16(3):317-26.

54.

2004

Daniel Paris; Nikunj Patel; Anthony DelleDonne; Amita Quadros; Robert Smeed; Michael Mullan

Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosis.


55.

2004

J Todd Roach; Claude-Henry Volmar; Samvid Dwivedi; Terrence Town; Robert Crescentini; Fiona

Crawford; Jun Tan; Michael Mullan

Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice.

Brain research 2004;1015(1-2):161-8.

56.

2004

Jiazhi Sun; Michelle A Blaskovich; Rishi K Jain; Frederic Delarue; Daniel Paris; Steven Brem;

Marguerite Wotoczek-Obadia; Qing Lin; Domenico Coppola; Kihang Choi; et al.

Blocking angiogenesis and tumorigenesis with GFA-116, a synthetic molecule that inhibits

binding of vascular endothelial growth factor to its receptor.

Cancer research 2004;64(10):3586-92.

57.

2004

Ryan T Mott; Ghania Ait-Ghezala; Terrence Town; Takashi Mori; Martina Vendrame; Jin Zeng; Jared

Ehrhart; Michae Michael Mullan ; Jun Tan

Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine

production.

Glia 2004;46(4):369-79.

58.

2004

Daniel Paris; Amita Quadros; James Humphrey; Nikunj Patel; Robert Crescentini; Fiona Crawford;

Michael Mullan

Nilvadipine antagonizes both Abeta vasoactivity in isolated arteries, and the reduced cerebral

blood flow in APPsw transgenic mice.

Brain research 2004;999(1):53-61.

59.

2004

Daniel Paris; Kirk Townsend; Amita Quadros; James Humphrey; Jiazhi Sun; Steven Brem; Marguerite

Wotoczek-Obadia; Anthony DelleDonne; Nikunj Patel; Demian F Obregon; et al.

Inhibition of angiogenesis by Abeta peptides.

Angiogenesis 2004;7(1):75-85.

60.

2003

Amita Quadros; Nikunj Patel; Robert Crescentini; Fiona Crawford; Daniel Paris; Michael Mullan

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Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw

transgenic mice.


61.

2003

Daniel Paris; James Humphrey; Amita Quadros; Nikunj Patel; Robert Crescentini; Fiona Crawford;

Michael Mullan

Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model

of Alzheimer's disease: role of inflammation.

Neurological research 2003;25(6):642-51.

62.

2003

Fiona C Crawford; Ghania Ait-Ghezala; Mark Morris; Maxine J Sutcliffe; Robert A Hauser; Archie

A Silver; Michael J Michael Mullan

Translocation breakpoint in two unrelated Tourette syndrome cases, within a region previously

linked to the disorder.

Human genetics 2003;113(2):154-61.

63.

2002

Jun Tan; Terrence Town; Fiona Crawford; Takashi Mori; Anthony DelleDonne; Robert Crescentini;

Demian Obregon; Richard A Flavell; Michael J Michael Mullan

Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice.

Nature neuroscience 2002;5(12):1288-93.

64.

2002

Terrence Town; Martina Vendrame; Anant Patel; Daniel Poetter; Anthony DelleDonne; Takashi Mori;

Robert Smeed; Fiona Crawford; Thomas Klein; Jun Tan; et al.

Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42).

Journal of neuroimmunology 2002;132(1-2):49-59.

65.

2002

Jun Tan; Terrence Town; Laila Abdullah; Yajaun Wu; Andon Placzek; Brent Small; Jodi Kroeger;

Fiona Crawford; Dan Richards; Michael Mullan

CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease.


66.

2002

K P Townsend; D Obregon; A Quadros; N Patel; Ch Volmar; D Paris; M Michael Mullan

Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature.

Annals of the New York Academy of Sciences 2002;977():65-76.

67.

2002

Robert L Yuspeh; Rodney D Vanderploeg; Timothy A Crowell; Michael Mullan

Differences in executive functioning between Alzheimer's disease and subcortical ischemic

vascular dementia.

Journal of clinical and experimental neuropsychology 2002;24(6):745-54.

68.

2002

Daniel Paris; Kirk P Townsend; Demian F Obregon; James Humphrey; Michael Mullan

Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain.

Prostaglandins & other lipid mediators 2002;70(1-2):1-12.

69.

2002

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Terrence Town; Joseph Zolton; Reed Shaffner; Billy Schnell; Robert Crescentini; Yajuan Wu; Jin

Zeng; Anthony DelleDonne; Demian Obregon; Jun Tan; et al.

p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro.

Journal of neuroscience research 2002;69(3):362-72.

70.

2002

Jun Tan; Terrence Town; Mike Michael Mullan

CD40-CD40L interaction in Alzheimer's disease.

Current opinion in pharmacology 2002;2(4):445-51.

71.

2002

G Ait-Ghezala; L Abdullah; R Crescentini; F Crawford; T Town; S Singh; D Richards; R Duara; M

Michael Mullan

Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample.


72.

2002

F C Crawford; R D Vanderploeg; M J Freeman; S Singh; M Waisman; L Michaels; L Abdullah; D

Warden; R Lipsky; A Salazar; et al.

APOE genotype influences acquisition and recall following traumatic brain injury.

Neurology 2002;58(7):1115-8.

73.

2002

Daniel Paris; Kirk P Townsend; James Humphrey; Demian F Obregon; Kiyoko Yokota; Michael Mullan

Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and

inflammation in rat aortae.

Atherosclerosis 2002;161(2):293-9.

74.

2002

Jun Tan; Terrence Town; Takashi Mori; Demian Obregon; Yajuan Wu; Anthony DelleDonne; Amyn

Rojiani; Fiona Crawford; Richard A Flavell; Mike Michael Mullan

CD40 is expressed and functional on neuronal cells.

The EMBO journal 2002;21(4):643-52.

75.

2002


Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling

elderly sample.

Alzheimer disease and associated disorders 2002;16(1):8-14.

76.

2002

J A Schinka; T Town; L Abdullah; F C Crawford; P I Ordorica; E Francis; P Hughes; A B Graves; J

A Mortimer; M Michael Mullan

A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and

other substances.

Molecular psychiatry 2002;7(2):224-8.

77.

2002


Apolipoprotein E genotype and cognitive impairment in community-dwelling black older adults.

International journal of psychiatry in medicine 2002;32(1):55-67.

78.

2001

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C Russ; J F Powell; J Zhao; M Baker; M Hutton; F Crawford; M Michael Mullan ; G Roks; M Cruts;

S Lovestone

The microtubule associated protein Tau gene and Alzheimer's disease--an association study and

meta-analysis.


79.

2001

T Town; J Tan; M Michael Mullan

CD40 signaling and Alzheimer's disease pathogenesis.

Neurochemistry international 2001;39(5-6):371-80.

80.

2001

T Mori; D Paris; T Town; A M Rojiani; D L Sparks; A Delledonne; F Crawford; L I Abdullah; J A

Humphrey; D W Dickson; et al.

Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic

APP(SW) mice.

Journal of neuropathology and experimental neurology 2001;60(8):778-85.

81.

2001

T Town; J Tan; N Sansone; D Obregon; T Klein; M Michael Mullan

Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42.


82.

2001

F C Crawford; M J Freeman; J A Schinka; M D Morris; L I Abdullah; D Richards; S Sevush; R

Duara; M J Michael Mullan

Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase

gene.

Experimental neurology 2001;167(2):456-9.

83.

2000

T Town; J Schinka; J Tan; M Michael Mullan

The opioid receptor system and alcoholism: a genetic perspective.


84.

2000

J Tan; T Town; M Michael Mullan

CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42

MAPK pathway.

The Journal of biological chemistry 2000;275(47):37224-31.

85.

2000

J Tan; T Town; T Mori; Y Wu; M Saxe; F Crawford; M Michael Mullan

CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42

mitogen-activated protein kinase.

The Journal of neuroscience : the official journal of the Society for Neuroscience

2000;20(20):7587-94.

86.

2000

F C Crawford; M J Freeman; J A Schinka; L I Abdullah; M Gold; R Hartman; K Krivian; M D Morris;

D Richards; R Duara; et al.

A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease.

Neurology 2000;55(6):763-8.

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87.

2000

D Paris; T Town; J Humphrey; K Yokota; M Michael Mullan

Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory

pathway.

Biochemical and biophysical research communications 2000;274(2):553-8.

88.

2000

A Tandon; E Rogaeva; M Michael Mullan ; P H St George-Hyslop

Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins.

Current opinion in neurology 2000;13(4):377-84.

89.

2000

F C Crawford; M J Freeman; J Schinka; L I Abdullah; D Richards; S Sevush; R Duara; M J Michael

Mullan

The genetic association between Cathepsin D and Alzheimer's disease.


90.

2000

B J Small; A B Graves; C L McEvoy; F C Crawford; M Michael Mullan ; J A Mortimer

Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?

Neurology 2000;54(11):2082-8.

91.

2000

Y M Kuo; F Crawford; M Michael Mullan ; T A Kokjohn; M R Emmerling; R O Weller; A E Roher

Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to

amyloid accumulation in Alzheimer's disease.

Molecular medicine (Cambridge, Mass.) 2000;6(5):430-9.

92.

2000

F Crawford; M Freeman; L Abdullah; J Schinka; M Gold; R Duara; M Michael Mullan

No association between the NOS3 codon 298 polymorphism and Alzheimer's disease in a sample from

the United States.

Annals of neurology 2000;47(5):687.

93.

2000

D Paris; T Town; T Parker; J Humphrey; M Michael Mullan

A beta vasoactivity: an inflammatory reaction.


94.

2000

Z Suo; G Su; A Placzek; A Kundtz; J Humphrey; F Crawford; M Michael Mullan

A beta vasoactivity in vivo.


95.

2000

D Paris; T Town; T Parker; J Humphrey; M Michael Mullan

beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating

agents.


96.

2000

D Paris; T Town; T Mori; T A Parker; J Humphrey; M Michael Mullan

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Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway.

Neurobiology of aging 2000;21(2):183-97.

97.

2000

F Crawford; L Abdullah; J Schinka; Z Suo; M Gold; R Duara; M Michael Mullan

Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease.


98.

2000

D Paris; T Town; M Michael Mullan

Novel strategies for opposing murine microglial activation.


99.

2000

S Sevush; G Peruyera; F Crawford; M Michael Mullan

Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with


The American journal of geriatric psychiatry : official journal of the American Association for

Geriatric Psychiatry 2000;8(3):254-6.

100.

2000

D G Harwood; W W Barker; R L Ownby; M J Michael Mullan ; R Duara

Family history of dementia and current depression in nondemented community-dwelling older adults.

Journal of geriatric psychiatry and neurology 2000;13(2):65-71.

101.

1999

J Tan; T Town; D Paris; T Mori; Z Suo; F Crawford; M P Mattson; R A Flavell; M Michael Mullan

Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

Science (New York, N.Y.) 1999;286(5448):2352-5.

102.

1999

J Tan; T Town; M Saxe; D Paris; Y Wu; M Michael Mullan

Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent

TNF-alpha production that is opposed by TGF-beta 1 and IL-10.

Journal of immunology (Baltimore, Md. : 1950) 1999;163(12):6614-21.

103.

1999

T Town; L Abdullah; F Crawford; J Schinka; P I Ordorica; E Francis; P Hughes; R Duara; M

Michael Mullan

Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency.

American journal of medical genetics 1999;88(5):458-61.

104.

1999

T Town; D Paris; T A Parker; A Kundtz; J Tan; R Duara; M Gold; F Crawford; M Michael Mullan

Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G

protein beta3, either independently or interactively with apolipoprotein E.


105.

1999

J Tan; T Town; Z Suo; Y Wu; S Song; A Kundtz; J Kroeger; J Humphrey; F Crawford; M Michael

Mullan

Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides.

Brain research bulletin 1999;50(2):143-8.

-12-


106.

1999

J Tan; T Town; A Placzek; A Kundtz; H Yu; M Michael Mullan

Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in

PC12 cells.


107.

1999

D L King; G W Arendash; F Crawford; T Sterk; J Menendez; M J Michael Mullan

Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for


Behavioural brain research 1999;103(2):145-62.

108.

1999

F Crawford; T Town; M Freeman; J Schinka; M Gold; R Duara; M Michael Mullan

The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control

sample.


109.

1999

G W Arendash; G C Su; F C Crawford; K B Bjugstad; M Michael Mullan

Intravascular beta-amyloid infusion increases blood pressure: implications for a vasoactive

role of beta-amyloid in the pathogenesis of Alzheimer's disease.


110.

1999

J Tan; T Town; D Paris; A Placzek; T Parker; F Crawford; H Yu; J Humphrey; M Michael Mullan

Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis.


111.

1999

F Crawford; M Freeman; T Town; D Fallin; M Gold; R Duara; M Michael Mullan

No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic

or population based samples.


112.

1999

D Paris; T Town; T A Parker; J Tan; J Humphrey; F Crawford; M Michael Mullan

Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in

microglia by a cGMP-dependent mechanism.


113.

1999

D G Harwood; W W Barker; R L Ownby; M Michael Mullan ; R Duara

Factors associated with depressive symptoms in non-demented community-dwelling elderly.


114.

1999

G C Su; G W Arendash; R N Kalaria; K B Bjugstad; M Michael Mullan

Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate

CNS glial cells and induce peripheral hemorrhage.

Brain research 1999;818(1):105-17.

115.

-13-


1999

D G Harwood; W W Barker; D A Loewenstein; R L Ownby; P St George-Hyslop; M Michael Mullan ; R

Duara

A cross-ethnic analysis of risk factors for AD in white Hispanics and white non-Hispanics.

Neurology 1999;52(3):551-6.

116.

1999

P N Pompl; M J Michael Mullan ; K Bjugstad; G W Arendash

Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive

impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.

Journal of neuroscience methods 1999;87(1):87-95.

117.

1998

Z Suo; J Humphrey; A Kundtz; F Sethi; A Placzek; F Crawford; M Michael Mullan

Soluble Alzheimers beta-amyloid constricts the cerebral vasculature in vivo.


118.

1998

W Barker; D Harwood; R Duara; M Michael Mullan ; D Fallin; P S Hyslop; E Rogaeva; Y Song

The APOE-epsilon4 allele and Alzheimer disease among African Americans, Hispanics, and whites.

JAMA : the journal of the American Medical Association 1998;280(19):1661-2; author reply 1663.

119.

1998

D Paris; T Town; T A Parker; J Humphrey; M Michael Mullan

Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by

Alzheimer's beta-amyloid peptide.


120.

1998

F Crawford; C Soto; Z Suo; C Fang; T Parker; A Sawar; B Frangione; M Michael Mullan

Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational

intermediate.

FEBS letters 1998;436(3):445-8.

121.

1998

Z Suo; J Tan; A Placzek; F Crawford; C Fang; M Michael Mullan

Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the

roles of cytokines and CD40.

Brain research 1998;807(1-2):110-7.

122.

1998

T Town; D Paris; D Fallin; R Duara; W Barker; M Gold; F Crawford; M Michael Mullan

The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease:

independent risk and linkage disequilibrium with the known APOE polymorphism.


123.

1998

R T Zori; J L Gardner; J Zhang; M J Michael Mullan ; R Shah; A R Osborn; H Houlden; M R

Wallace; S Roberts; T P Yang

Newly described form of X-linked arthrogryposis maps to the long arm of the human X chromosome.


124.

1998

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D Paris; T A Parker; T Town; Z Suo; C Fang; J Humphrey; F Crawford; M Michael Mullan

Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40

peptide.


125.

1998

F Crawford; D Fallin; Z Suo; L Abdullah; M Gold; A Gauntlett; R Duara; M Michael Mullan

The butyrylcholinesterase gene is neither independently nor synergistically associated with

late-onset AD in clinic- and community-based populations.


126.

1998

F Crawford; Z Suo; C Fang; M Michael Mullan

Characteristics of the in vitro vasoactivity of beta-amyloid peptides.


127.

1997

F Crawford; Z Suo; C Fang; A Sawar; G Su; G Arendash; M Michael Mullan

The vasoactivity of A beta peptides.


128.

1997

G C Su; G W Arendash; R N Kalaria; M J Michael Mullan

Long-term venous A beta 1-40 infusion in rats causes lung hemorrhage and brain perivascular

gliosis.


129.

1997

F Crawford; Z Suo; C Fang; M Michael Mullan

beta-Amyloid peptides and enhancement of vasoconstriction by endothelin-1.


130.

1997

D Fallin; A Kundtz; T Town; A C Gauntlett; R Duara; W Barker; F Crawford; M Michael Mullan

No association between the low density lipoprotein receptor-related protein (LRP) gene and

late-onset Alzheimer's disease in a community-based sample.


131.

1997

X Cai; D Fallin; J Stanton; P Scibelli; R Duara; F Crawford; M Michael Mullan

APOE is linked to Alzheimer's disease in a large pedigree.


132.

1997

T Town; D Fallin; F Crawford; S Walsh; R Solomon; M Michael Mullan

Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic

schizophrenia.


133.

1997

Z Suo; C Fang; F Crawford; M Michael Mullan

Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial

toxicity.

-15-


Brain research 1997;762(1-2):144-52.

134.

1997

D Fallin; S Reading; J Schinka; J Hoyne; P Scibelli; M Gold; F Crawford; M Michael Mullan

No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's

disease.


135.

1997

X Cai; J Stanton; D Fallin; J Hoyne; R Duara; M Gold; S Sevush; P Scibelli; F Crawford; M

Michael Mullan

No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic

and population-based samples.


136.

1997

D Fallin; A C Gauntlett; P Scibelli; X Cai; R Duara; M Gold; F Crawford; M Michael Mullan

No association between the very low density lipoprotein receptor gene and late-onset

Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and

clinic samples.

Genetic epidemiology 1997;14(3):299-305.

137.

1996

M Michael Mullan ; P Scibelli; R Duara; D Fallin; M Gold; J Schinka; J Hoyne; A Osborne; S

Sevush; F Crawford

Familial and population-based studies of apolipoprotein E and Alzheimer's disease.


138.

1996

F Crawford; J Hoyne; X Cai; A Osborne; D Poston; J Zaglul; N Dajani; S Walsh; R Bradley; R

Solomon; et al.

Dopamine DRD2/Cys311 is not associated with chronic schizophrenia.


139.

1996

T Thomas; G Thomas; C McLendon; T Sutton; M Michael Mullan

beta-Amyloid-mediated vasoactivity and vascular endothelial damage.

Nature 1996;380(6570):168-71.

140.

1995

S E Poduslo; D Riggs; J Schwankhaus; A Osborne; F Crawford; M Michael Mullan

Association of apolipoprotein E but not B with Alzheimer's disease.

Human genetics 1995;96(5):597-600.

141.

1995

F Crawford; J Hoyne; P Diaz; A Osborne; J Dorotheo; D Sheehan; M Michael Mullan

Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder.


142.

1995

C Bennett; F Crawford; A Osborne; P Diaz; J Hoyne; R Lopez; P Roques; R Duara; M Rossor; M

Michael Mullan

Evidence that the APOE locus influences rate of disease progression in late onset familial

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Alzheimer's Disease but is not causative.


143.

1995

M Michael Mullan ; C Bennett; C Figueredo; D Hughes; R Mant; M Owen; A Warren; M McInnis; A

Marshall; P Lantos

Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14.


144.

1994

M Michael Mullan ; F Crawford

The molecular genetics of Alzheimer's disease.

Molecular neurobiology 1994;9(1-3):15-22.

145.

1994

M Michael Mullan ; F Crawford; J Buchanan

Technical feasibility of genetic testing for Alzheimer's disease.

Alzheimer disease and associated disorders 1994;8(2):102-15.

146.

1993

M Michael Mullan ; H Houlden; F Crawford; A Kennedy; P Rogues; M Rossor

Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology.


147.

1993

M Michael Mullan ; F Crawford

Genetic and molecular advances in Alzheimer's disease.

Trends in neurosciences 1993;16(10):398-403.

148.

1993

M Michael Mullan ; S Tsuji; T Miki; T Katsuya; S Naruse; K Kaneko; T Shimizu; T Kojima; I

Nakano; T Ogihara

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val-->Ile mutation

in the amyloid precursor protein gene.

Neurobiology of aging 1993;14(5):407-19.

149.

1993

H Houlden; F Crawford; M Rossor; M Michael Mullan

Screening for the APP codon 670/671 mutations in Alzheimer's disease.


150.

1993

H Houlden; M Michael Mullan

Alzheimer's disease aetiology: amyloid and chromosome 14.

British journal of hospital medicine 1993;49(8):535-6.

151.

1993

A M Kennedy; S Newman; A McCaddon; J Ball; P Roques; M Michael Mullan ; J Hardy; M C

Chartier-Harlin; R S Frackowiak; E K Warrington

Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor

protein gene (amyloid precursor protein 717 valine-->glycine).

Brain : a journal of neurology 1993;116 ( Pt 2)():309-24.

152.

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1993

J Brown; S Gydesen; S A Sorensen; A Brun; S Smith; H Houlden; R Twells; M Michael Mullan ; M

Rossor; J Collinge

Genetic characterization of a familial non-specific dementia originating in Jutland, Denmark.

Journal of the neurological sciences 1993;114(2):138-43.

153.

1992

M Michael Mullan ; H Houlden; M Windelspecht; L Fidani; C Lombardi; P Diaz; M Rossor; R Crook;

J Hardy; K Duff

A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal

to the alpha 1-antichymotrypsin gene.

Nature genetics 1992;2(4):340-2.

154.

1992

M Michael Mullan

Familial Alzheimer's disease: second gene locus located.

BMJ (Clinical research ed.) 1992;305(6862):1108-9.

155.

1992

K J Johnson; T Sander; A A Hicks; A van Marle; D Janz; M J Michael Mullan ; B P Riley; M G

Darlison

Confirmation of the localization of the human GABAA receptor alpha 1-subunit gene (GABRA1) to

distal 5q by linkage analysis.

Genomics 1992;14(3):745-8.

156.

1992

J Hardy; M Michael Mullan

Alzheimer's disease. In search of the soluble.

Nature 1992;359(6393):268-9.

157.

1992

M Michael Mullan ; F Crawford; K Axelman; H Houlden; L Lilius; B Winblad; L Lannfelt

A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of

beta-amyloid.

Nature genetics 1992;1(5):345-7.

158.

1992

L Fidani; K Rooke; M C Chartier-Harlin; D Hughes; R Tanzi; M Michael Mullan ; P Roques; M

Rossor; J Hardy; A Goate

Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor

protein gene in familial Alzheimer's disease: identification of a further family with APP717

Val-->Ile.

Human molecular genetics 1992;1(3):165-8.

159.

1992

J Collinge; J Brown; J Hardy; M Michael Mullan ; M N Rossor; H Baker; T J Crow; R Lofthouse; M

Poulter; R Ridley

Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features.

Brain : a journal of neurology 1992;115 ( Pt 3)():687-710.

160.

1992

F Crawford; M C Chartier-Harlin; M Michael Mullan ; J Hardy; A Delacourte; G Arnott

Alzheimer's--a correction.

-18-


Nature 1992;356(6368):390.

161.

1992

P L Lantos; P J Luthert; D Hanger; B H Anderton; M Michael Mullan ; M Rossor

Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and

sporadic Alzheimer's disease have the same cytoskeletal pathology.


162.

1992

J Hardy; M C Chartier-Harlin; M Michael Mullan

Alzheimer disease: the new agenda.

American journal of human genetics 1992;50(3):648-51.

163.

1992

C L Katona; M Michael Mullan ; C Taylor

Depressive disorders and organic brain disorders: validation of the depressive signs scale.

Clinical neuropharmacology 1992;15 Suppl 1 Pt A():169A-170A.

164.

1991

F Crawford; J Hardy; M Michael Mullan ; A Goate; D Hughes; L Fidani; P Roques; M Rossor; M C

Chartier-Harlin

Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with

early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence.


165.

1991

R C Pearson; M Michael Mullan ; J Hardy; P J Harrison

Nicotine intake and Alzheimer's disease.

BMJ (Clinical research ed.) 1991;303(6798):361.

166.

1991

M C Chartier-Harlin; F Crawford; K Hamandi; M Michael Mullan ; A Goate; J Hardy; H Backhovens;

J J Martin; C V Broeckhoven

Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended

pedigrees with early onset Alzheimer's disease.


167.

1991

D L Ewins; M N Rossor; J Butler; P K Roques; M J Michael Mullan ; A M McGregor

Association between autoimmune thyroid disease and familial Alzheimer's disease.

Clinical endocrinology 1991;35(1):93-6.

168.

1991

C M van Duijn; C van Broeckhoven; J A Hardy; A M Goate; M N Rossor; A Vandenberghe; J J Martin;

A Hofman; M J Michael Mullan

Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease.

The British journal of psychiatry : the journal of mental science 1991;158():471-4.

169.

1991

M Michael Mullan

A genetic defect causing Alzheimer's disease.

British journal of hospital medicine 1991;45(3):131.

170.

-19-


1991

A Goate; M C Chartier-Harlin; M Michael Mullan ; J Brown; F Crawford; L Fidani; L Giuffra; A

Haynes; N Irving; L James

Segregation of a missense mutation in the amyloid precursor protein gene with familial


Nature 1991;349(6311):704-6.

171.

1991

M J Michael Mullan ; L Giuffra; J A Hardy; I Ovenstone; A R Haynes; L A James; R Williamson; P

J Newton; M J Owen; P Roques

Clinical and pathologic features of chromosome 21-linked familial Alzheimer's disease.


172.

1991

J Brown; S Smith; A Brun; J Collinge; S Gydesen; J Hardy; M Michael Mullan ; A Goate

Genetic characterization of a novel familial dementia.


173.

1990

P H St George-Hyslop; J L Haines; L A Farrer; R Polinsky; C Van Broeckhoven; A Goate; D R

McLachlan; H Orr; A C Bruni; S Sorbi; et al.

Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder.

Nature 1990;347(6289):194-7.

174.

1990

J Clinton; P L Lantos; M Rossor; M Michael Mullan ; G W Roberts

Immunocytochemical confirmation of prion protein.

Lancet 1990;336(8713):515.

175.

1990

J Collinge; F Owen; M Poulter; M Leach; T J Crow; M N Rossor; J Hardy; M J Michael Mullan ; I

Janota; P L Lantos

Prion dementia without characteristic pathology.

Lancet 1990;336(8706):7-9.

176.

1990

S Hodgkinson; M J Michael Mullan ; H M Gurling

The role of genetic factors in the etiology of the affective disorders.

Behavior genetics 1990;20(2):235-50.

177.

1990

L A Farrer; R H Myers; L A Cupples; P H St George-Hyslop; T D Bird; M N Rossor; M J Michael

Mullan ; R Polinsky; L Nee; L Heston

Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for

heterogeneity.

Neurology 1990;40(3 Pt 1):395-403.

178.

1990

A M Goate; J A Hardy; M J Owen; A Haynes; L James; M Farrall; M J Michael Mullan ; P Roques; M

N Rossor

Genetics of Alzheimer's disease.

Advances in neurology 1990;51():197-8.

179.

-20-


1990

M J Owen; M J Michael Mullan

Molecular genetic studies of manic-depression and schizophrenia.

Trends in neurosciences 1990;13(1):29-31.

180.

1989

J A Hardy; A M Goate; M J Owen; M J Michael Mullan ; M N Rossor; R C Pearson

Modelling the occurrence and pathology of Alzheimer's disease.

Neurobiology of aging 1989;10(5):429-31; discussion 446-8.

181.

1989

M J Michael Mullan ; R M Murray

The impact of molecular genetics on our understanding of the psychoses.


182.

1989

A M Goate; A R Haynes; M J Owen; M Farrall; L A James; L Y Lai; M J Michael Mullan ; P Roques;

M N Rossor; R Williamson

Predisposing locus for Alzheimer's disease on chromosome 21.

Lancet 1989;1(8634):352-5.

183.

1989

J A Hardy; M J Owen; A M Goate; L A James; A R Haynes; M N Rossor; P Roques; M J Michael Mullan

Molecular genetics of Alzheimer's disease.

Biochemical Society transactions 1989;17(1):75-6.

184.

1986

M J Michael Mullan ; H M Gurling; B E Oppenheim; R M Murray

The relationship between alcoholism and neurosis: evidence from a twin study.


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