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DSM Nutritional Products strength to succeed HyD ® - The strength to succeed Unlimited. DSM

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DSM Nutritional Products

strength to succeed

Hy•D® - The strength to succeed

Unlimited.DSM

Unlimited.DSM

11 Hy•D® • STRENGTH TO SUCCEED

Black Cyan Magenta Yellow CUTTER GUIDE DO NOT PRINT

51939 ©

DSM Nutritional Products Ltd.

Designed by: Mono Design Limited 10/2008

DSM Nutritional Products LtdP.O. Box 2676CH-4002 BaselSwitzerland

www.dsmnutritionalproducts.com

IntroductionTo remain profitable in today’scompetitive, global marketspoultry producers, whether theyproduce broilers, layers or tur-keys, must supply a whole-some, competitively-pricedproduct that meets and ideallyexceeds the increasing de-mands of the consumer.

At the same time they must strive to in-crease the efficiency of their units tomaximize profits and minimize waste and losses.

Feed continues to be the single biggestcost of poultry production and all produ-cers must develop and feed diets thatallow birds to exploit their full genetic po-tential. This means diets that maximizeproduction while ensuring the bird re-mains fit and healthy. Increasingly theemphasis is being placed on micro nu-trients.

The importance of stronghealthy birdsWhatever the system of production, mo-dern birds must have a strong skeleton.However due to rapid growth and inten-sive production conditions, birds are in-creasingly susceptible to lameness. Thereason is that the skeletal system hasbeen unable to keep completely up withthe genetic improvements in body mass.

A robust skeleton is affected by manyfactors with nutrition playing a major rolein its development. Specifically calcium,phosphorus and vitamin D3 are essentialto strengthen the skeleton and promotemaintenance of healthy bones. VitaminD3, or more specifically the metabolite 25-hydroxyvitamin D3 is vital for optimalcalcium and phosphorus utilization.

25-hydroxyvitamin D3 plays a crucial role in:• Bone mineralization• Calcium and phosphorus homeostasis• Remodeling the structural bones• Immune system modulation• Muscle satellite cells.

Birds fed vitamin D3 have to convert it into 25-hydroxyvitamin D3 via a complex met-abolic pathway. Research and practicalexperiences worldwide show that moderncommercial poultry are not able to con-vert enough vitamin D3 into 25-hydroxyvi-tamin D3 to provide optimum levels of themetabolite to support the birds’ require-ments, especially under intensive produc-tion condition with rapid growth rates,high egg output and enteric disease bur-dens.

2

What is Hy•D®

?

Hy•D® • STRENGTH TO SUCCEED

Hy•D® - The immediatealternativeHy•D® is a unique feed additive whichcontains 25-hydxoxyvitamin D3 and sobypasses the metabolic step which has tobe undergone by standard vitamin D3.Furthermore, intestinal binding proteinsshow a higher affinity to 25-hydxoxyvitaminD3 than to vitamin D3, thus resulting in amore efficient and faster uptake.

Trials worldwide have shown that addingHy•D® to poultry diets will improve:• Bone and skeletal formation• Muscle development• Calcium and phosphorus absorption• Immune response.

It is not a case of feeding more, it is acase of feeding better!

It is not possible to achieve the benefitsof feeding Hy•D® just by greatly incre-asing the inclusion rate of vitamin D3.

Overdosing vitamin D3 may also affect theabsorption of other fat soluble vitamins bycompeting for lipoproteins that function astransporters for nutrients.

Feeding Hy•D® will maximize the produc-tivity of growing and laying birds undercommercial conditions.

Hy•D® • STRENGTH TO SUCCEED3

Hy•D®Vitamin D3

the shorter the journey...…the greater the benefits

BroilersProfitable commercial broiler production requires:• Low mortality• High skeleton strength• High yields of breast meat• Minimal carcass condemnations.

Modern broilers face a number of skeletal health challengeswhich can affect performance and meat quality. A strongerskeleton translates into more meat and can reduce the numberof birds either condemned or downgraded by the processor.Hy•D® is proven to provide the nutritional technology to improvephysiological development, overall poultry health and animalwelfare.

Specifically Hy•D® delivers the following benefits:• Enhanced bird welfare by minimizing leg abnormalities• Minimized rickets & metabolic bone diseases, such as tibial

dyschondroplasia• Improved survivability and growth rates• Reduced wastage & down-grades at processing• Improved breast meat yield.

Hy•D® gives your birds better, strongerbones resulting in more efficient birdswith better breast meat yieldBirds fed Hy•D® grow faster and use feed more efficiently.Research from trials across the major poultry producingcountries has indicated responses of the order of:

• 2-3% increased daily liveweight gain

• 1-2% improvement in feed conversion

• 2-4% increased in breast meat yield.

You want more breast meat -Hy•D® delivers

Supplementing diets with Hy•D® increases the yield ofbreast meat in commercial trials.

You want stronger birds - Hy•D® delivers

Birds fed Hy•D® had a lower level of lameness.

Developing a stronger skeleton will help reduce lameness andmortality in growth-out units.

Chickens with leg problems are commonly downgraded, leadingto an economic loss. Leg problems are commonly associatedwith birds that have an immature digestive tract or face entericchallenges while also being required to grow quickly. Hy•D®

helps ensure a strong skeleton is developed, even during periodsof enteric challenge. Hy•D® has also been shown to play an im-portant role in the development of a robust immune system.

Stronger bones are also proven to improve food safety throughreducing levels of contamination in processing plants.

Control with Hy•D®

Subjective lameness score - good = 1, poor = 52.5

2

1.5

1

0.5

0

4

Broilers

Breast meat yield21.8

%

21.7

21.6

21.5

21.4

21.3

21.2

21.1

21

20.9

20.8Control with Hy•D®

Source: APSI (2007) - US

Source: APSI (2007) - US

Hy•D® • STRENGTH TO SUCCEED5

Reduced Black Bone SyndromeConsumers place considerable importance on the appearanceof poultry meat and use it as an indicator of quality. Discoloredchicken meat is considered a quality defect and leads to rejec-tion. Poultry processors worldwide suggest that as many as30% of bone-in chicken thighs are affected by discolored meatclose to the bone after cooking – Black Bone Syndrome.

Where skeletal maturity at slaughter is lower the consequence isincreased bone porosity. This leads to leaching of blood andbone marrow into the surrounding tissue and results in darke-ning of the meat. The more rapid growth rate displayed by mo-dern broilers means that they achieve a lower level of skeletalmaturity at slaughter leading to a greater incidence of BlackBone Syndrome.

Feeding Hy•D® helps improve skeletal structureand reduce the incidence of Black Bone Syndrome.

Adding Hy•D® to the diet of fast-growing broilers resulted ingreater consumer acceptance of thigh meat, due to the redu-ced incidence of black discoloration of the thigh meatnext to the femur.

Adding Hy•D® to broiler diets can help improveperformance and profits.

trabecularbone

bone marrowleakage

cortical bone

thigh

bone marrow

Analysis of consumer perception of acceptance of thigh meat

Black Bone Syndrome

Control

like

with Hy•D®

neither like nor dislike dislikeSource: University of Alberta (Korver et al 2006)

BreedersTo build better and more eggs or chicks, you must firstbuild a better hen.

Profitability in breeder units is directly related to:• Lay persistence• Minimizing mortality• Maximizing hatchability• One-day old chick quality.

Eggs are a means to an end. To be globally competitive it isessential to maximize the number of chicks per housed hen.

There is a direct relationship between the pullet's developmentduring rearing and subsequent performance during the layingcycle. The best way to increase persistence of lay andensure high shell quality is to maximize the strengthof the pullet’s frame before sexual maturity.

Many of the problems which occur during the early part of lay,including mortality can be traced back to the growing period.To avoid these problems, pullets must be fed in a manner thatwill allow optimal body development during the growing period.

Breeders fed Hy•D® will have the optimum levels of25-hydroxyvitamin D3 required to support the birds’ skeletaldevelopment despite the stresses of production and/orenteric disease insults.

You want more hatched eggs per hen -Hy•D® deliversHatchability

Feeding Hy•D® increased both liveability and rate of layleading to a significant increase in total egg production.

6

Liveability Eggs/hen* Hatching Total% (eggs/hen)* eggs

Control 95.70 75.07 70.47 2,560,000

With Hy•D® 96.64 78.68 74.60 2,680,000

Difference +0.94 +3.61 +4.14 +120,000

Breeders

* period: 18 monthsSource: Commercial trials (2004) - Brazil

Hy•D® • STRENGTH TO SUCCEED7

HatchabilityTo maximize the profitability of breeding operations, it isnecessary to produce as many eggs per housed hen aspossible, while optimizing the hatchability rate and thequality of day-old-chicks.

Optimal nutritional status of breeders is essential for the effectivetransfer of nutrients to the embryo. Higher concentrations ofessential nutrients are associated with improved hatchability,livability, performance and healthier chickens.

Numerous trials show that the maternal supplementation withHy•D® increases hatchability and the number of first qualitychicks. Hy•D® supports the development of the embryo and itimproves chick early innate immune function.

You want higher hatchability -Hy•D® delivers

You want lower early embryo mortality -Hy•D® delivers

Including Hy•D® in breeder diets can improve the key areasaffecting profitability

Early mortality

5

6

7

4%

3

2

1

0Control with Hy•D®

Hatchability and fertility

94

96

98

92%

90

88

86

84Fertility Hatchability

Control with Hy•D®

University of Alberta (Korver and Saunders-Blades, 2005) – Canada

Source: Commercial trials (2005) – Arkansas

LayersLayer units face similar challenges to breeder units.Early-lay metabolic disorders associated with calciumhomeostasis can have a detrimental effect on performance,reducing bird health and the persistency of lay.

Profitable egg production relies on strong healthy birds, minimalhen mortality, good rates of lay and shell strength. To build betterand more eggs, you must first build a better bird and the key tothis is maximizing the pullet’s frame development before it reachessexual maturity and maintaining it during the production cycle.

Research has shown that an optimal early frame developmentand an adequate maintenance during production are linked toimproved shell quality.

Feeding Hy•D® to layers can help:• Achieve better bone development• Adequate calcium/phosphorus metabolism• Increase rates of lay• Increase lay persistence• Improve shell quality.

You want more eggs and stronger shells -Hy•D® delivers

Including Hy•D® in layer diets resulted in more eggswith better egg shell quality

You want fewer broken eggs -Hy•D® delivers

In trials flocks fed Hy•D® saw a 20% reduction in the inci-dence of broken shells.

Egg production Egg shell strength88.5

%

88

87.5

87

86.5

86

85.5Control with Hy•D® Control with Hy•D®

Control

Month 1 Month 2 Month 3 Month 4 Month 5 Month 6

0.75

with Hy•D®

2.5

2

1.5

1

0.5

0

1.030.78 0.96

1.571.25

1.9

1.28

2.141.83

1.18

8

Layers

Broken eggs

%br

oken

eggs

Source: Avila et al. (2004) – Mexico

Source: Soto-Salanova and Hernandez (2004) – Spain

3600

3550

3500

3450

3400

3350

3300

g/m

m2

Including Hy•D® in layer diets can improve the keyareas affecting profitability.

Hy•D® • STRENGTH TO SUCCEED

TurkeysProfitability in turkey production depends on achieving heavy,healthy birds with significant yields of high quality breast meat.Variance in carcass composition have lead to increasedincidence of locomotive problems in the final stages of turkeyrearing often leading to a need to compromise on breast meat yield.

During periods of rapid growth the assimilation of vital nutrientsinto bone can be compromised leading to a weaker skeleton andleg problems. Improving skeletal integrity in turkeys can improvebird welfare as well as allowing producers to maximize breast meatyield and profitability.

Hy•D® has been shown to help prevent some of the skeletalchallenges and:• Improve locomotion and fitness• Improve liveweight and feed conversion• Increase breast meat yield• Reduce carcass condemnations• Improve animal welfare.

You want fitter birds - Hy•D® delivers

Feeding Hy•D® resulted in birds with increased skeletalstrength resulting in improved locomotion.

You want larger turkeys - Hy•D® delivers

Birds fed Hy•D® were on average 7% heavier.

You want increased breast meat yield -Hy•D® delivers

Birds fed Hy•D® had on average 3.5 % increase inbreast meat yield.

11.54

11.52

11.5kg

11.48

11.46

11.44

11.42

11.4Control with Hy•D®

23.4

23.2

23

22.8

22.6

22.4

22.2

22Control with Hy•D®

11.56

Control With Hy•D®

Locomotive difficulties 12 weeks 72.3a 81.3a

top marks A, % 15 weeks 60.4a 80.4b

(A = Normal mobility)

Maximum load resulting 15 weeks 695 733in fracture, N

9

Turkeys

Liveweight

Breast meat yield

%

Source: Larroudé et al 2005

Source: Larroudé et al. (2005) – France

Source: Larroudé et al. (2005) – France

Walking ability

Including Hy•D® in turkey diets can improve the keyareas affecting profitability.

10

QualityDSM Quality you can trustAs market leader, DSM Nutritional Products constantly strives tomaintain and advance its own high quality standards. The aim isnot only to give our customers the peace of mind that onlycomes with a superior quality supply but also to be thebenchmark for the industry.

FormulationThe enhanced formulation utilizing patented spray-dried beadlettechnology used to produce ROVIMIX® Hy•D® provides a moreuniform, better flowing product with good mixability properties.

StabilityROVIMIX®Hy•D® is stable when included in pelleted feeds understandard conditions.

ROVIMIX®Hy•D® 1.25% the DSM product form that warrantsoptimal supplementation of 25-hydroxyvitamin D3 in feed.

Recommended Inclusion Rates

25-OHD3 ROVIMIX® Hy•D® 1.25%

Broiler, Breeder, Layer 69mg/mt 5.52g/mt

Turkey 92mg/mt 7.36g/mt

When using Hy•D® with vitamin D3 in the same diet, verify thatthe existing maximum permitted concentration of vitamin D3

is not exceeded. Your local DSM representative can supportyou in this verification.

Depending on production objectives, your nutritionist or DSMrepresentative may suggest alternative feeding programs.

Stability of ROVIMIX Hy•D 1.25% in pelleted feed, after processing

100

80

60

40

20

0trial 1:70ºc

after processing

%re

cove

ry

after processing & 1 month storage

pelleting temperaturetrial 1:75ºc trial 1:85ºc trial 1:90ºc trial 2:80ºc

8895 92

8597

83

You want to generate profit -Hy•D® delivers

DSM Nutritional Products

strength to succeed

Hy•D® - The strength to succeed

Unlimited.DSM

Unlimited.DSM

Black Cyan Magenta Yellow CUTTER GUIDE DO NOT PRINT

51939 ©

DSM Nutritional Products Ltd.

Designed by: Mono Design Limited 10/2008

DSM Nutritional Products LtdP.O. Box 2676CH-4002 BaselSwitzerland

www.dsmnutritionalproducts.com

DSM Nutritional Products

strength to succeed

Hy•D® - The strength to succeed

Unlimited.DSM

Unlimited.DSM

11 Hy•D® • STRENGTH TO SUCCEED

Black Cyan Magenta Yellow CUTTER GUIDE DO NOT PRINT

51939 ©

DSM Nutritional Products Ltd.

Designed by: Mono Design Limited 10/2008

DSM Nutritional Products LtdP.O. Box 2676CH-4002 BaselSwitzerland

www.dsmnutritionalproducts.com