elsha ghina novtaress
TRANSCRIPT
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5 Reasons to recognize Compounds
CannabidiolUsually, when it comes to marijuana, people were thinking that marijuana
would make "giting" and dangerous for consumption. hey think like this
because the public generally only knows one acti!e compound in marijuana is
C #etrahydrocannabinol$. C is the compound that makes the wearer feel
the effects of euphoria or commonly spelled "giting". %hat has not been much
public know marijuana is one of the compounds named
Cannabidiol.&ndonesian'hare Cannabidiol #C()$, are compounds that are non*
psychoacti!e cannabis that has great therapeutic properties for health.
C() high le!els can enhance the positi!e effects of C while pressing
the negati!e effects of C as paranoid and feeling uncertain. C() cooperation
with C in the way it works. %hen used separately, C() or C would notbe as effecti!e as treating chronic pain as if they are used simultaneously. he
problem is, the farmers realized that since the first C was as an attraction that
sells marijuana, C gi!es a sense of euphoria and giting and this is what has
always been associated with marijuana. o impro!e the content of C, they
are trying to eliminate C from certain types of cannabis, so the result of
marijuana that gi!es high e+perience psychoacti!e effects, which are considered
dangerous by those who support marijuana prohibition laws. he difference
between the use of C and C() simultaneously and the use of pure C
ere are some reasons why we need to know C() closer ..
5 C() repair brain damage caused by alcohol.
-ccording to research at the Uni!ersity of entucky, C() brain change
physiologically and can repair damage due to acute alcoholic. he study found
that C() could reduce ner!e damage as much as /0.01 in the entorhinal
corte+. here ha!e been many who know if some suction cannabis can relie!e a
hango!er, but this study focuses on the potential treatment of marijuana to a
new le!el.
/ C() effecti!ely cope with se!ere social an+iety.
2any ha!e claimed that marijuana to relie!e their an+iety while others say the
opposite. his is because the content of the C() in e!ery different marijuana
plants. - study is held to determine the impact of the C() on social an+iety in
public speaking. urns out they were pre!iously gi!en a dose of C(), an+iety
and ner!ous they diminished during their public speaking. he researchers
stated that the C() has many ad!antages compared with other anti*depressant
drugs because of the effect that fast with not cause a sense of dependency.
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3 C() kill cancer cells are found in metastasis #other organs in!ol!ed terjalar
cancer cells$
Researchers at the California 4acific 2edical Center found that C() kill cancer
cells to spread. his study also makes UC- study on marijuana does not cause
lung cancer becomes more attracti!e6 &s own cannabinoids may be able toeliminate carcinogens #cancer*causing$ which are found in cigarettes7
&s it true that marijuana is a real anti*cancer drugs7
8 C() is an anti*psychotic drugs are powerful.
- clinical trial in 9ermany found that the C() effecti!ely treat schizophrenia
as usual anti*psychotic drugs with little side effects. his shows yin*yang on
cannabis compounds which ha!e the effect of high doses of C psychotic.
C() was the one that suppresses the negati!e properties of C. -nd for this
reason the C() well for those who ha!e a family history of mental disorders.
: -nd the last is, legally.
;es, in some state laws for medical marijuana has been legalized. hey can
plant, culti!ate, e!en buy marijuana in accordance with the regulations set by
the go!ernment they are. his means they ha!e easy access to cheap drugs.
C() can be processed into food, be!erage, oil, capsules, lotions, and e!en
chewing gum.
-ddiction
Chronic marijuana use can lead to physical and psychological
dependence, and e+perience withdrawal symptoms shortly after stopping use.hese symptoms may occur after chronic use for at least 3 weeks. hese
symptoms peaked on day /, and began to be resol!ed within 8 weeks calculated
from the last time use traditional cannabis. characteristic withdrawal symptoms
are restlessness, decreased appetite, nausea, irritability and sleep disruption
?4ope @ ;urgelum*odd, :AAB. &n general, these symptoms will only make the
user feel uncomfortable but no threat to life.
8. Cogniti!e )ysfunction
Chronic Cannabis 'yndrome, better known by the term -moti!ational
'yndrome is cogniti!e impairment in chronic users which resulted in a decrease
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in the ability to plan or get the purpose of life6 then causes the user is placed in a
job that reDuires only low*le!el cognition.
Research on humans and animals indicate that the use of cannabis at an
early age long impact on cognition and increase the likelihood neuropsikis
disorders ?'chneider, 8EE0. %ilson et al. ?8EEE compared the long*termmarijuana users who start mengganja at the age of :F years and below :F years
and abo!e. &n pengganja which began at the age of :F years and below shows
the low percentage of gray matter ?neurons and dendrites, where the thought
process occurs and the high percentage of white matter ?myelinated a+ons
compared with whole brain !olume.
3. 2ental illness
2any studies show that there is a correlation between the use of cannabis
with high risk of psychosis and some studies ha!e found a link between the doseresponse of psychosis ?Gergusson, 4oulton, 'mith, @ (oden, 8EEB6 Hammit,
-llebeck, -ndreasson, undberg, @ ewis, 8EE8. after browsing through the
a!ailable e!idence, of the many results of published research can be concluded
that cannabis use may increase the risk of psychosis in young people, but it has
a significant effect on those who ha!e a predisposition psychosis.
/. Cancer
Research in this area manunjukan many contradictions. 'idney,
Iuesenberry, Griedman, @ ekawa ?:AAF found that smoking marijuana is not
at all associated with an increased risk of cancer. 2eanwhile, in different places,
Gligiel ?:AAF, found that histological and molecular changes in the bronchial
epithelium similar between smoking cannabis with tobacco smoking. he
conclusion that can be drawn while, there ha!e not been enough studies to
pro!ide an e!aluation that is strong enough to suggest that smoking marijuana
associated with cancer risk.
5. Reproduction
intensi!ecannabis ?olodny, 2asters, olodner, @ oro, :AF/. GKC?forced e+piratory !olume in the first secondsetelah take a deep breath,
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diffusion capacity, or hyperacti!e breathing as occurs in tobacco smokers
?etrault, Crothers, @ 2oore, 8EEF.
Physical advantage Marijuana Users
Lust as we ''
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P!"C!PLE# E#P$"#!%LE C&""&%!E# U#E
Remember the days when the smoke has not enacted legislation7 2any
smokers who smoke anywhere6 eating at home, in the office, house of worship,e!en in public transport. Ginally, many are bothered by cigarette smoke,
especially those who do not smoke. hen diberlakukanlah go!ernment
regulations to maintain order in the smoke, so that all the people * smoke or not
* feel comfortable and not feel disad!antaged.
ikewise with marijuana, if marijuana is legalized then there will be legal
regulations go!erning the distribution and use of marijuana. 'o many Duestions
that came to us with regard to what would happen if marijuana was legalized.
heir concern minors will be using marijuana and disturbing achie!ement in
school, or the number of people who use marijuana e!erywhere, causing unrestin the community, a lot of abuse and e!erywhere much under the influence of
marijuana.
%e really understand their concerns about the impact of legalizing
marijuana in public, medical and leisure. his is because as long as the
go!ernment participated in the anti*marijuana propaganda by the U= global
cannabis prohibition law, it is understandable that there are many people who
oppose the legalization of marijuana because of bad information about
marijuana they recei!ed and their ignorance of marijuana itself.
'o, what would happen if marijuana is legalized7 ow to order whichwould regulate the distribution and use of marijuana for the con!enience
together7 ooks like we can learn from policies that ha!e been implemented by
the de!eloped countries that ha!e legalized marijuana, one of which was made
by the organizationNs (oard of =
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to those who are still minors are they growing as a responsible adult. -dult
means thinking about any decision to be taken carefully and be accountable for
the decisions and outcomes of those decisions. -nd those whoN!e grown
obligations was to demonstrate to those who are still under the age of what it
means to a responsible adulthose who want to use marijuanaN!e done it earlier though the legal status
of marijuana is still illegal. -nd indeed there will be some other adults who will
use marijuana if marijuana is regulated by the go!ernment. he legal regulation
of marijuana would regulate the circulation of marijuana that the law would be
different with cigarettes, alcohol, soda, and e!en heroin. -nd for teenagers and
those who are still minors, the legal regulation of marijuana would likely
narrow the scope of the black market that sells marijuana to them. -nd the legal
regulations ensure marijuana is sold only in the place specified by the
go!ernment with a reasonable law, one of which is to pro!e that the person isold enough to get marijuana and memilliki permission from doctors to use
marijuana as their treatment #if legalized for medical special$. -nd where the
sale of marijuana were gi!en permission by the go!ernment will lose its right to
sell marijuana if pro!en to ha!e been sold to those who are still minors.
P J+cept for patients who are still minors who super!ised his marijuana use
and on the recommendation of a doctor
8. )ri!ing.
Responsible cannabis users do not dri!e a motor !ehicle or other
dangerous machinery during the influence of marijuana, as well as the influence
of other drugs. -lthough e+perts say that the use of marijuana is safer than
alcohol and other drugs, but the safety of the public wants those who are under
the influence of marijuana should not get in the way and a way to know how
many le!els of marijuana on the dri!er under the influence of marijuana should
be de!eloped and used rather than test it chemically. his does not mean the
e!idence that cannabis ad!ersely affect the ner!es of motion. 2any studies
pro!e that the dri!ing influence of marijuana is harmless compared to the
influence of alcohol. Under the influence of alcohol, dri!ers tend not careful,
feeling bra!e and challenged, and improper coordination. %hile the dri!erunder the influence of marijuana tend to dri!e with caution, not ambition to
dri!e Duickly, and was not challenged to penetrate the personal speed record.
-lthough many feel able to get behind the wheel, traffic*related legal marijuana
regulations reDuire them to not dri!ing for the sake of common security.
(ecause the law banning marijuana has been pro!en unsuccessful and
had a lot of people who use cannabis despite the illegal status, then it is time to
accept the fact that the legal regulation of marijuana would likely prohibit those
under the influence of cannabis on dri!ing. %ith the enforcement of marijuana
laws regulations6 time, energy, and funds the go!ernment to arrest those whouse cannabis are the responsibility of the home > not in a public place, could be
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di!erted to allow the police to arrest the real offenders, including the dri!er who
is under the influence of marijuana.
3. 'ituation @ Conditions.
Responsible cannabis users will be cautious in beha!ior, procedures, andregulate its use with either. "he situation" here refers to setting the !alues,
attitudes, e+perience and personality, and "condition" here relates to the
physical and social situation of the users of the marijuana. Responsible
marijuana users will always be aware of the situation and condition, place, time,
mood, etc. and did not hesitate to say "=
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Countries in the 'orld thats een legali*e cannais
ere is a list of the countries in the world that ha!e legalized marijuana
possession.
:. =etherlands * Cannabis can be bought and consumed directly in
"Coffeshop," but sell and consume marijuana outside Coffeshop, illegal.
'ince :AFB, the =etherlands has been a leader in reforming the =arcotics
-ct to draw a clear distinction between soft drugs ?soft drugs and hea!y
drugs ?hard drugs. 2arijuana into the mild narcotic and legal groups in
limited Duantities.
8. 9ermany *
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:E.(elgium * -ccording to the law, adults can carry up to 3 gramganja.
(elgium is one of the first countries to make perbedaanhukum between
"4ossession of cannabis for personal use and other types of drug type of
offense."
::.Czech Republic * 'ince 8E:E, possession of drugs and psychotropic
already didekriminalisasi. (ecause according to the study, the =arcotics
-ct tidakhanya increase pra!elensi drug use in the country, but also failed
to stop the illicit trafficking of illicit drugs.
:8.(razil * )ecriminalization of marijuana and drug decriminalization of
personal untukkeperluan in place since 8EEB. &t is the result of =arcotics
re!isiUU massi!ely in 8EEB.
:3.Chile * Consuming marijuana in small amounts is allowed as long as it isdone in the home and alone.
:/.Uruguay *
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!n Cannais Com+ounds !nhiit Cancer
Compounds found in marijuana is belie!ed by scientists United 'tates
can stop the spread of breast cancer throughout the body.
he team of "California 4acific 2edical Center Research &nstitute" hope thatcannabidiol or C() could be a non*to+ic alternati!e to chemotherapy.
Unlike cannabis, C() does not ha!e the characteristics of psychoacti!e so that
its use does not !iolate the law, the report of the "2olecular Cancer
herapeutics".
he author emphasizes that they do not ad!ise patients to smoke
marijuana.
hey add that it is !ery unlikely that effecti!e concentrations of C() could be
reached by smoking cannabis.
C() works by blocking the acti!ity of a gene called &d*: are belie!ed to beresponsible for the aggressi!e spread of cancer cells from the tumor site of
origin * a process called metastasis. 4re!ious research has shown that C() can
block aggressi!e human brain cancers. Recent research found that C()
appeared to ha!e a similar effect on breast cancer in laboratory
5 2arijuana Compounds hat Could elp Combat
Cancer, -lzheimers, 4arkinsons ?&f
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because they naturally occur in the marijuana plant.
hats right. &n the eyes of the U' go!ernment, these non*psychotropic
cannabinoids are as dangerous to consume as heroin and they possess absolutelyno therapeutic utility. &n the eyes of many scientists, howe!er, these
cannabinoids may offer a safe and effecti!e way to combat some of the worlds
most se!ere and hard*to*treat medical conditions. eres a closer look at some
of these promising, yet illegal, plant compounds.
Cannabidiol
-fter C, C() is by far the most studied plant cannabinoid. Girst identified in
:A/E ?though its specific chemical structure was not identified until :AB3,
many researchers now describe C() as Duite possibly the most single important
cannabinoid in the marijuana plant. hat is because C() is the cannabinoid that
arguably possesses the greatest therapeutic potential.
- key word search on the search engine 4ub2ed Central, the U.'. go!ernmentrepository for peer*re!iewed scientific research, re!eals o!er :,EEE papers
pertaining to C() S with scientists interest in the plant compound increasing
e+ponentially in recent years. &ts easy to understand why. - cursory re!iew of
the literature indicates that C() holds the potential to treat dozens of serious
and life*threatening conditions.
T'tudies ha!e suggested a wide range of possible therapeutic effects of
cannabidiol on se!eral conditions, including 4arkinsons disease, -lzheimers
disease, cerebral ischemia, diabetes, rheumatoid arthritis, other inflammatory
diseases, nausea and cancer. hat was theconclusionof researcher -ntonio
Huardi, writing about C() in the (razilian Lournal of 4sychiatry in 8EE0. -
8EEA literature re!iewpublished by a team of &talian and &sraeli in!estigators
indicates that the substance likely holds e!en broader clinical potential. hey
acknowledged that C() possesses an+iolytic, antipsychotic, antiepileptic,
neuroprotecti!e, !asorela+ant, antispasmodic, anti*ischemic, anticancer,
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462008000300015&lng=en&nrm=iso&tlng=enhttp://www.ncbi.nlm.nih.gov/pubmed/19729208http://www.ncbi.nlm.nih.gov/pubmed/19729208http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462008000300015&lng=en&nrm=iso&tlng=en -
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antiemetic, antibacterial, antidiabetic, anti*inflammatory, and bone stimulating
properties. 2artin ee, cofounder and director of the non*profit group 4roject
C()S which identifies and promotes C()*rich strains of cannabis S agrees.
Cannabidiol is Tthe Cinderella molecule, writes ee in his new book, 'moke'ignalsO - 'ocial istory of 2arijuana S 2edical, Recreational, and 'cientific
?'cribner, 8E:8. T#&ts$ the little substance that could. #&ts$ nonto+ic,
nonpsychoacti!e, and multicapable.
&ts also e+ceptionally safe for human consumption. -ccording to a just
published clinical trialin the journal Current 4harmaceutical )esign, the oral
administration of BEE mg of C() in :B subjects was associated with no acutebeha!ioral and physiological effects, such as increased heart rate or sedation.
T&n healthy !olunteers, V C() has pro!en to be safe and well tolerated,
authors affirmed. - 8E:: literature re!iewpublished in Current )rug 'afety
similarly concluded that C() administration, e!en in doses of up to :,/5E
milligrams per day, is non*to+ic, well tolerated, and safe for human
consumption.
;et despite calls from !arious researchers to allow for clinical trials to assess the
use of C() in the treatment of !arious ailments, includingbreast cancer, colon
cancer,prostate cancer, and schizophrenia, a re!iew of the website S the online
registry for federally supported federal trials worldwide S identifies only four
U'*based clinical assessments of C(). wo of these are safety studies6 the
other two are e!aluations of C()s potential to mitigate cra!ings for heroin and
opiates. 'ati!e+, a pharmaceutically produced, patented oromucosal spraycontaining e+tracts of C and C(), is also undergoing testing in =orth
-merica for use as a cancer pain relie!er under the name =abi+imols. he drug
is already a!ailable by prescription in Canada, the United ingdom, and
throughout much of Jurope for the treatment of !arious indications, including
multiple sclerosis.
4resently, howe!er, options for U' patients wishing to utilize C() are
e+tremely limited. 2ost domestically grown strains of cannabis contain
http://www.projectcbd.com/http://www.projectcbd.com/http://www.ncbi.nlm.nih.gov/pubmed/22716148http://www.ncbi.nlm.nih.gov/pubmed/22129319http://www.ncbi.nlm.nih.gov/pubmed/16728591http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339795/?tool=pubmedhttp://www.nature.com/tp/journal/v2/n3/full/tp201215a.htmlhttp://clinicaltrials.gov/http://www.gwpharm.com/sativex.aspxhttp://www.projectcbd.com/http://www.projectcbd.com/http://www.ncbi.nlm.nih.gov/pubmed/22716148http://www.ncbi.nlm.nih.gov/pubmed/22129319http://www.ncbi.nlm.nih.gov/pubmed/16728591http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339795/?tool=pubmedhttp://www.nature.com/tp/journal/v2/n3/full/tp201215a.htmlhttp://clinicaltrials.gov/http://www.gwpharm.com/sativex.aspx -
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relati!ely little C()and many smaller*sized cannabis dispensaries do not
consistently carry such boutiDue !arieties. - handful of prominent cannabis
dispensaries, mostly in California and Colorado, do carry C()*rich strains of
cannabis or C()*infused products. owe!er, in recent months, se!eral of thesepro!iders, such as arborside ealth Center in
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shown to promote anti*cancer acti!ity in malignant cell lines and to possess
bone*stimulating properties. 2ore recently, a 8E:: preclinical trialreported that
C(C influences ner!e endings abo!e the spine to modify sensations of pain.
T#his$ compound might represent #a$ useful therapeutic agent with multiplemechanisms of action, the study concluded.
Cannabigerol
'imilar to C(C, cannabigerol ?C(9 also has been subject to relati!ely few
scientific trials since its disco!ery in :AB/. o date, there e+ist only limited
number of papers a!ailable referencing the substance S a keyword search on4ub2ed yields fewer than 55 citations S which has been documented to possess
anti*cancer, anti*inflammatory, analgesic, and anti*bacterial properties.
-ccording to a 8E:: re!iewpublished in the (ritish Lournal of 4harmacology,
T#-$ whole plant e+tract of a C(9*chemotype V would seem to offer an
e+cellent, safe new antiseptic agent for the treatment of multi*drug resistant
bacteria. - more recent re!iewpublished this year in the journal 4harmacology
@ herapeutics further acknowledges that C(9 and similar non*psychotropiccannabinoids Tact at a wide range of pharmacological targets and could
potentially be utilized in the treatment of a wide range of central ner!ous system
disorders, including epilepsy.
etrahydrocannabi!arin
)isco!ered in :AFE, tetrahydrocannabi!arin ?CK is most typically identified
in 4akistani hashish and cannabis strains of southern -frican origin. )ependingon the dose, CK may either antagonize some of the therapeutic effects of
C ?e.g., at low doses CK may repress appetite or promote them. ?igher
doses of CK e+erting beneficial effects on bone formation and fracture
healing in preclinical models, for e+ample. Unlike, C(), C(=, C(C, C(9,
high doses of CK may also be mildly psychoacti!e ?but far less so than
C.
o date, fewer than 3E papers a!ailable on 4ub2ed specifically reference
CK.
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anticon!ulsant properties, as well as its ability to mitigate inflammation and
pain S in particular, difficult*to*treat neuropathy.
ike C(), CK is on the radar of (ritish biotech 9% 4harmaceuticals
?makers of 'ati!e+. -ccording to its website, the company has e+pressedinterest in the potential use of tetrahydrocannabi!arin in the treatment of
obesity, diabetes and other related metabolic disorders. hough the compound
has been subject to 4hase & clinical testing, a keyword search
on clinicaltrials.go!yields no specific references to any ongoing studies at thistime.
Low-dose vaporized cannabis signifcantly improvesneuropathic pain.
%e conducted a double*blind, placebo*controlled, crosso!er study
e!aluating the analgesic efficacy of !aporized cannabis in subjects, the majority
of whom were e+periencing neuropathic pain despite traditional treatment.
hirty*nine patients with central and peripheral neuropathic pain underwent a
standardized procedure for inhaling medium*dose ?3.531, low*dose ?:.8A1,
or placebo cannabis with the primary outcome being !isual analog scale pain
intensity.
4sychoacti!e side effects and neuropsychological performance were alsoe!aluated. 2i+ed*effects regression models demonstrated an analgesic response
to !aporized cannabis. here was no significant difference between the 8 acti!e
dose groupsN results ?4 X .F. he number needed to treat ?== to achie!e 3E1
pain reduction was 3.8 for placebo !ersus low*dose, 8.A for placebo !ersus
medium*dose, and 85 for medium* !ersus low*dose. -s these ==s are
comparable to those of traditional neuropathic pain medications, cannabis has
analgesic efficacy with the low dose being as effecti!e a pain relie!er as the
medium dose.
4sychoacti!e effects were minimal and well tolerated, and
neuropsychological effects were of limited duration and readily re!ersible
within : to 8 hours. Kaporized cannabis, e!en at low doses, may present an
effecti!e option for patients with treatment*resistant neuropathic pain.
PERSPECTIVE:
he analgesia obtained from a low dose of delta*A*tetrahydrocannabinol
?:.8A1 in patients, most of whom were e+periencing neuropathic pain despite
con!entional treatments, is a clinically significant outcome. &n general, the
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931567/?tool=pubmedhttp://www.gwpharm.com/Metabolic%20Disorders.aspxhttp://clinicaltrials.gov/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931567/?tool=pubmedhttp://www.gwpharm.com/Metabolic%20Disorders.aspxhttp://clinicaltrials.gov/ -
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effect sizes on cogniti!e testing were consistent with this minimal dose. -s a
result, one might not anticipate a significant impact on daily functioning.
Marijuana Lin,ed To %etter %rain unction !n
%i+olar Patients
Results from a new study show indicate that bipolar patients with a
history of marijuana use ha!e better neurocogniti!e function than those who
ha!e ne!er used cannabis.
he team, from he Hucker illside ospital in 9len
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e!aluations and completed a battery of tests measuring neurocogniti!e
functioning.
here were no significant differences between patients who used
cannabis ?"suffered from CU)" and those who didnNt, regarding age, race, or
education, the researchers wrote inPsychiatry Research.(ut, according to the
researchers, patients with "Cannabis Use )isorder" were more likely to ha!e a
history of psychosis than those who didnNt toke up, at 08 percent !ersus BF.3
percent.
(ut patients "with CU)" ?dammit, & mean pot smokers had significantly
better attention, processing speed>set*shifting, and working memory than those
without, putting the lie to the tired old stereotypes of "burnouts" and "stoners."
"hese analyses indicate an interesting pattern suggesting superior
neurocogniti!e performance among bipolar patients with comorbid CU) when
compared to bipolar patients without a history of cannabis use," (raga and team
concluded. "2oreo!er, this cogniti!e ad!antage is noted in spite of e!idence of
a more se!ere clinical course."
"%e hope that the results from this study will help guide and encourage future
large studies and help further elucidate the multifaceted associations and
possible impact of cannabis use in bipolar disorder," the researchers wrote
Cannais Can .el+ in &l*heimers %attle
-dd another link to the growing chain of studies showing that certain
chemicals found in the cannabis plant can help -lzheimerNs patients.- study
published earlier this year in the Lournal of -lzheimerNs )isease shows that C
can slow or end the progress of the disease.
(ut itNs more complicated than gi!ing patients a joint to toke ** though puffing
apparently has itNs benefits as well. Researchers at the Uni!ersity of 'outh
Glorida treated isolated -lzheimerNs cells in a lab with !arying amounts of C.
he results show that C reduces or eliminates the protein buildup associated
with the disease.
-lzheimerNs attacks the brain by building up plaDues that cause
inflammation. 2arijuana, coincidentally, has amazing anti*inflammatoryproperties.
http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327 -
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"C is known to be a potent antio+idant with neuroprotecti!e properties, but
this is the first report that the compound directly affects -lzheimerNs pathology
by decreasing amyloid beta le!els, inhibiting its aggregation, and enhancing
mitochondrial function," the studyNs lead author wrote in the journal. ")ecreased
le!els of amyloid beta means less aggregation, which may protect against the
progression of -lzheimerNs disease. 'ince C is a natural and relati!ely safe
amyloid inhibitor, C or its analogs may help us de!elop an effecti!e
treatment in the future."
(ut e!en toking up regularly can help pre!ent the disease from taking
hold, according to some studies. -n
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kind used in the morning as an energy booster and treatment of other chronic
diseases.
Rick 'impson always make e+tracts of the type of strong &ndica, but
cannabis &ndica dominant result of cross breeding it is 'ati!a can produce goode+tract. here are thousands of types of cannabis that has been repeatedly cross
are married and each has a different effect on health. 'ome types of marijuana
good for pain relief, while others return to control blood sugar le!els for
diabetics or ocular pressure glaucoma patients.
)osage and reatmentO
ake e+tract :>3 the size of grain of rice and put it on the tip of the inde+
finger. 4ut the e+tract at some point of the gums ?see illustration below.2o!ement of the tip of the inde+ finger slowly and circle until the e+tract was
stuck in the gums. ift the finger and repeat the same process on the other
gums. )o this until the e+tracts were stuck in the fingers disappeared.
Remember that patients can use all parts of their gums to put e+tracts. %hen
patients use false teeth, false teeth off the first and did as instructed abo!e.
Cannabis e+tract is a powerful drugM 4atients should really understand
this. -lways start treatment with the lowest dose ?:>3 grain of rice and
gradually increase the dose until :gram per day. : gram dose is the dose
reDuired to kill !arious diseases, especially cancer. &t takes appro+imately 5
weeks until the patient is able to consume : gram of e+tract per day. %ith
increasing dosage, the patient should be carefully di!iding the amount of e+tract
consumed each day. 4atients should really take the time to find the dosage and
how to use the right in this treatment.
4atients can use the size of one big seed e+tract e!ery day as a precaution
and maintaining a healthy body.
ipsO
4atients will reDuire adaptation time until the body is completely ready to
recei!e this drug. J!eryone has a system adaptation is different, so patients
really need to be sure and patient. 2ost patients reDuire 3*5 days of adaptation.
&f carried out in accordance with the procedures, this treatment will not
cause a sense of high ?euphoria. 2any patients do not feel the effects of the
e+tract when you first use and then add the dose itself, conseDuently there is a
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sense of euphoria at times une+pected. &f patients follow the instructions gi!en
in the near future patients will feel small changes in e!eryday until finally
reaching a healthy condition completely.
(e sure to use cannabis e+tract in the morning. Lump*start with breakfast,brush teeth, mouth wash, and use the e+tract according the manufacturerNs
instructions. -lways use the e+tract after eating and repeat these steps each time
the patient wants to consume the e+tract. his pre!ents sticking cannabis e+tract
in the lefto!ers and then attached to the teeth or swallowed into the stomach
?may cause high > euphoria.
&ncreasing doses of the e+tract means increasing the freDuency of use,
instead of adding a dose e!ery time wear. Gor e+ample, you are able to consume
: rice seed e+tract e!ery day and wants to increase the dose to : Y grains of
rice. ;our use of rice seed e+tract 8 Y times a day or eDual to taking one grain
of rice e!ery day. o reach :Y grain rice, you only need to use the e+tract three
times a day with the same dose. &f you want to increase the dose to 8 grains of
rice a day, you eat four times a day6 and so on.
: gram of e+tract daily dose is usually di!ided into 0*:E times
consumption. his method is !ery helpful because it can create a system in the
body of the patient remains stable.
4atients should feel the changes that occur in the body. &f patients
e+perience nausea, eating snacks and drinking water is sufficient to suppress it.
&f allowed to occur, the patient may feel an+iety. &mmediately eat and drink
water to o!ercome.
%hen using cannabis e+tract, make sure the body of water consumed.
-lthough patients do nothing, your metabolism will increase patient during
e+tract react. 2ake sure there is water around the patient and drink immediatelyafter the patient urinated.
4atients should consult with a health care professional if you want to use
the e+tract and still under treatment6 especially with regard to blood pressure
medication, pain and sleep. Remember to always drink water and li!e a healthy
lifestyle.
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C() protection against Jbola !irus
here is good scientific e!idence that cannabis compounds in particular
Cannabidiol the possibility to control the immune system and protection from
!iral infection. Cannabis has been known as inhibitors of fungi and bacteria and
is considered as a new class of antimicrobials for work differently from otherantimicrobials.
Jbola is a !irus R=- comple+ organism that causes cells to "eat"
pinocytosis #e!ents liDuid intake into the cell$ and then the !irus hijacks the cell
to replicate itself. Replication in!ol!es can in!ol!e many mutations in the R=-
code that would make it difficult if not impossible to make an effecti!e !accine.
here is a U' patent that shows e!idence that the anti*!iral acti!ity of
compounds.
Usually the !irus*infected cells will produce a surface protein that is
identified as a foreign body and the immune system will attack the cells were
infected with this. Jbola !irus infection causes the cells to produce proteins that
hide the !irus from the immune system. his mechanism allows the !iral R=-
to hide the infected cells by the immune system to protect dr.
he cause of death by this !irus is the immune system responds to the
!irus in!eksi. his is the cause of mortality and morbidity from this in!eksi.
Gurthermore, the !irus triggers the immune cells to release enzymes #cytokinesO
a protein made by cells that affect the beha!ior of other cells$ that they hold.
he release of this enzyme causes lymphocytes #a type of white blood cells in
the immune system of !ertebrates being$ the other to release more cytokines.
his process is also called a cytokine storm.
'mall blood clots in the blood !essels of the so*called )&C #)isseminated
&ntra!ascular Coagulation$ cause coagulopathy #blood clotting disorders or
e+cessi!e bleeding$ where blood would not clot simultaneously with )&C#bleeding and clotting occurs at the same time$. 'ymptoms of shock against
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to+ins #o+ic 'hock 'yndrome$ occurs when cytokines are released causing
blood !essels to dilate in such a way.2arijuana compounds pro!en to reduce
and pre!ent against to+ic shock and )&C ?8
Jbola !irus also attacks the attachment of the cells caused by killer cellsimmune to release KJ9G #!ascular endothelial growth factorO signaling proteins
produced by cells that menstimulasi!asculogenesis and angiogenesis. &t is part
of a system that restores o+ygen supply to tissues when blood circulation is
inadeDuate$ which resulted in the destruction of the tight relationship between
the cells and lead to leaking of fluid between cells until bleeding.
Cannabis compounds can inhibit KJ9G processes that occur in the
relationship between cells.
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* - method for treating diseases of the immune function that produces an
infection such as 'imian &mmunodeficiency Kirus, Geline &mmunodeficiency
Kirus, erpes 'imple+ !irus, Jpstein*(arr !irus, cytomegalo!irus, hepatitis (
and C, influenza !irus, rhino!irus and in!eksimikrobakteri use Cannabidiol
deri!ati!e claim 8
* U' 4atent this, pro!ing that cannabis compounds to treat disorders of the
immune system called a cytokine storm caused by different !iruses ?/
* &n the description, the patent U' pro!ed that the regulation of the immune
system may be the key to the sur!i!al of people with &K and can be applied to
the sur!i!al of patients with Jbola. he process of direct lethal marijuana
compounds #!irus infection$ pro!ed in &K infection ?/ but not on Jbola.
owe!er, inhibition of KJ9G is essential to pre!ent leakage of endothelial
#lining cells that line blood !essels and lymph, li!er, and other body ca!ities$
and bleeding.
(ecause marijuana is !ery safe to eat, especially under the super!ision of a
doctor, the authors belie!e that snagat important for the medical community to
begin human trials for the sake of the sur!i!al of the Jbola !irus sur!i!al
regardless of political obstacles.
ReferencesO
: -ntibacterial Cannabinoids from Cannabis sati!aO - 'tructure * -cti!ity
'tudy -ntibacterial Cannabinoids from Cannabis sati!aO - 'tructure * -cti!ity
'tudy6 9io!anni -ppendino et al. he 'chool of 4harmacy, Uni!ersity of
ondon
8 4rotection -gainst 'eptic 'hock and 'uppression of umor =ecrosis Gactor Zand =itric
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5 Curr 4harm )ecember 8EEB6 :8 ?8/O 3:35*/B. Cannabinoids, immune
system and cytokine network. 2assi 4Kaccani -4arolaro ), Uni!ersity of
&nsubria, Kia -. da 9iussano :E, 8:E58 (usto -rsizio ?K-, &taly
B Cancer Res -ugust :5, 8EE/ B/6 5B:F Cannabinoids inhibit the KascularJndothelial 9rowth Gactor 4athway in 9liomas Cristina (l[zDuez
;4JR&= "httpO>>cancerres.aacrjournals.org>content>B/>:B>5B:F.full":,
F ow Cannabis 2ight eep Coronary 'tents ...>how*cannabis*might*keep*coronary*stents*open*longer, Lune
:E, 8E:/ )a!id -llen 2)