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    5 Reasons to recognize Compounds

    CannabidiolUsually, when it comes to marijuana, people were thinking that marijuana

    would make "giting" and dangerous for consumption. hey think like this

    because the public generally only knows one acti!e compound in marijuana is

    C #etrahydrocannabinol$. C is the compound that makes the wearer feel

    the effects of euphoria or commonly spelled "giting". %hat has not been much

    public know marijuana is one of the compounds named

    Cannabidiol.&ndonesian'hare Cannabidiol #C()$, are compounds that are non*

    psychoacti!e cannabis that has great therapeutic properties for health.

    C() high le!els can enhance the positi!e effects of C while pressing

    the negati!e effects of C as paranoid and feeling uncertain. C() cooperation

    with C in the way it works. %hen used separately, C() or C would notbe as effecti!e as treating chronic pain as if they are used simultaneously. he

    problem is, the farmers realized that since the first C was as an attraction that

    sells marijuana, C gi!es a sense of euphoria and giting and this is what has

    always been associated with marijuana. o impro!e the content of C, they

    are trying to eliminate C from certain types of cannabis, so the result of

    marijuana that gi!es high e+perience psychoacti!e effects, which are considered

    dangerous by those who support marijuana prohibition laws. he difference

    between the use of C and C() simultaneously and the use of pure C

    ere are some reasons why we need to know C() closer ..

    5 C() repair brain damage caused by alcohol.

    -ccording to research at the Uni!ersity of entucky, C() brain change

    physiologically and can repair damage due to acute alcoholic. he study found

    that C() could reduce ner!e damage as much as /0.01 in the entorhinal

    corte+. here ha!e been many who know if some suction cannabis can relie!e a

    hango!er, but this study focuses on the potential treatment of marijuana to a

    new le!el.

    / C() effecti!ely cope with se!ere social an+iety.

    2any ha!e claimed that marijuana to relie!e their an+iety while others say the

    opposite. his is because the content of the C() in e!ery different marijuana

    plants. - study is held to determine the impact of the C() on social an+iety in

    public speaking. urns out they were pre!iously gi!en a dose of C(), an+iety

    and ner!ous they diminished during their public speaking. he researchers

    stated that the C() has many ad!antages compared with other anti*depressant

    drugs because of the effect that fast with not cause a sense of dependency.

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    3 C() kill cancer cells are found in metastasis #other organs in!ol!ed terjalar

    cancer cells$

    Researchers at the California 4acific 2edical Center found that C() kill cancer

    cells to spread. his study also makes UC- study on marijuana does not cause

    lung cancer becomes more attracti!e6 &s own cannabinoids may be able toeliminate carcinogens #cancer*causing$ which are found in cigarettes7

    &s it true that marijuana is a real anti*cancer drugs7

    8 C() is an anti*psychotic drugs are powerful.

    - clinical trial in 9ermany found that the C() effecti!ely treat schizophrenia

    as usual anti*psychotic drugs with little side effects. his shows yin*yang on

    cannabis compounds which ha!e the effect of high doses of C psychotic.

    C() was the one that suppresses the negati!e properties of C. -nd for this

    reason the C() well for those who ha!e a family history of mental disorders.

    : -nd the last is, legally.

    ;es, in some state laws for medical marijuana has been legalized. hey can

    plant, culti!ate, e!en buy marijuana in accordance with the regulations set by

    the go!ernment they are. his means they ha!e easy access to cheap drugs.

    C() can be processed into food, be!erage, oil, capsules, lotions, and e!en

    chewing gum.

    -ddiction

    Chronic marijuana use can lead to physical and psychological

    dependence, and e+perience withdrawal symptoms shortly after stopping use.hese symptoms may occur after chronic use for at least 3 weeks. hese

    symptoms peaked on day /, and began to be resol!ed within 8 weeks calculated

    from the last time use traditional cannabis. characteristic withdrawal symptoms

    are restlessness, decreased appetite, nausea, irritability and sleep disruption

    ?4ope @ ;urgelum*odd, :AAB. &n general, these symptoms will only make the

    user feel uncomfortable but no threat to life.

    8. Cogniti!e )ysfunction

    Chronic Cannabis 'yndrome, better known by the term -moti!ational

    'yndrome is cogniti!e impairment in chronic users which resulted in a decrease

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    in the ability to plan or get the purpose of life6 then causes the user is placed in a

    job that reDuires only low*le!el cognition.

    Research on humans and animals indicate that the use of cannabis at an

    early age long impact on cognition and increase the likelihood neuropsikis

    disorders ?'chneider, 8EE0. %ilson et al. ?8EEE compared the long*termmarijuana users who start mengganja at the age of :F years and below :F years

    and abo!e. &n pengganja which began at the age of :F years and below shows

    the low percentage of gray matter ?neurons and dendrites, where the thought

    process occurs and the high percentage of white matter ?myelinated a+ons

    compared with whole brain !olume.

    3. 2ental illness

    2any studies show that there is a correlation between the use of cannabis

    with high risk of psychosis and some studies ha!e found a link between the doseresponse of psychosis ?Gergusson, 4oulton, 'mith, @ (oden, 8EEB6 Hammit,

    -llebeck, -ndreasson, undberg, @ ewis, 8EE8. after browsing through the

    a!ailable e!idence, of the many results of published research can be concluded

    that cannabis use may increase the risk of psychosis in young people, but it has

    a significant effect on those who ha!e a predisposition psychosis.

    /. Cancer

    Research in this area manunjukan many contradictions. 'idney,

    Iuesenberry, Griedman, @ ekawa ?:AAF found that smoking marijuana is not

    at all associated with an increased risk of cancer. 2eanwhile, in different places,

    Gligiel ?:AAF, found that histological and molecular changes in the bronchial

    epithelium similar between smoking cannabis with tobacco smoking. he

    conclusion that can be drawn while, there ha!e not been enough studies to

    pro!ide an e!aluation that is strong enough to suggest that smoking marijuana

    associated with cancer risk.

    5. Reproduction

    intensi!ecannabis ?olodny, 2asters, olodner, @ oro, :AF/. GKC?forced e+piratory !olume in the first secondsetelah take a deep breath,

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    diffusion capacity, or hyperacti!e breathing as occurs in tobacco smokers

    ?etrault, Crothers, @ 2oore, 8EEF.

    Physical advantage Marijuana Users

    Lust as we ''

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    P!"C!PLE# E#P$"#!%LE C&""&%!E# U#E

    Remember the days when the smoke has not enacted legislation7 2any

    smokers who smoke anywhere6 eating at home, in the office, house of worship,e!en in public transport. Ginally, many are bothered by cigarette smoke,

    especially those who do not smoke. hen diberlakukanlah go!ernment

    regulations to maintain order in the smoke, so that all the people * smoke or not

    * feel comfortable and not feel disad!antaged.

    ikewise with marijuana, if marijuana is legalized then there will be legal

    regulations go!erning the distribution and use of marijuana. 'o many Duestions

    that came to us with regard to what would happen if marijuana was legalized.

    heir concern minors will be using marijuana and disturbing achie!ement in

    school, or the number of people who use marijuana e!erywhere, causing unrestin the community, a lot of abuse and e!erywhere much under the influence of

    marijuana.

    %e really understand their concerns about the impact of legalizing

    marijuana in public, medical and leisure. his is because as long as the

    go!ernment participated in the anti*marijuana propaganda by the U= global

    cannabis prohibition law, it is understandable that there are many people who

    oppose the legalization of marijuana because of bad information about

    marijuana they recei!ed and their ignorance of marijuana itself.

    'o, what would happen if marijuana is legalized7 ow to order whichwould regulate the distribution and use of marijuana for the con!enience

    together7 ooks like we can learn from policies that ha!e been implemented by

    the de!eloped countries that ha!e legalized marijuana, one of which was made

    by the organizationNs (oard of =

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    to those who are still minors are they growing as a responsible adult. -dult

    means thinking about any decision to be taken carefully and be accountable for

    the decisions and outcomes of those decisions. -nd those whoN!e grown

    obligations was to demonstrate to those who are still under the age of what it

    means to a responsible adulthose who want to use marijuanaN!e done it earlier though the legal status

    of marijuana is still illegal. -nd indeed there will be some other adults who will

    use marijuana if marijuana is regulated by the go!ernment. he legal regulation

    of marijuana would regulate the circulation of marijuana that the law would be

    different with cigarettes, alcohol, soda, and e!en heroin. -nd for teenagers and

    those who are still minors, the legal regulation of marijuana would likely

    narrow the scope of the black market that sells marijuana to them. -nd the legal

    regulations ensure marijuana is sold only in the place specified by the

    go!ernment with a reasonable law, one of which is to pro!e that the person isold enough to get marijuana and memilliki permission from doctors to use

    marijuana as their treatment #if legalized for medical special$. -nd where the

    sale of marijuana were gi!en permission by the go!ernment will lose its right to

    sell marijuana if pro!en to ha!e been sold to those who are still minors.

    P J+cept for patients who are still minors who super!ised his marijuana use

    and on the recommendation of a doctor

    8. )ri!ing.

    Responsible cannabis users do not dri!e a motor !ehicle or other

    dangerous machinery during the influence of marijuana, as well as the influence

    of other drugs. -lthough e+perts say that the use of marijuana is safer than

    alcohol and other drugs, but the safety of the public wants those who are under

    the influence of marijuana should not get in the way and a way to know how

    many le!els of marijuana on the dri!er under the influence of marijuana should

    be de!eloped and used rather than test it chemically. his does not mean the

    e!idence that cannabis ad!ersely affect the ner!es of motion. 2any studies

    pro!e that the dri!ing influence of marijuana is harmless compared to the

    influence of alcohol. Under the influence of alcohol, dri!ers tend not careful,

    feeling bra!e and challenged, and improper coordination. %hile the dri!erunder the influence of marijuana tend to dri!e with caution, not ambition to

    dri!e Duickly, and was not challenged to penetrate the personal speed record.

    -lthough many feel able to get behind the wheel, traffic*related legal marijuana

    regulations reDuire them to not dri!ing for the sake of common security.

    (ecause the law banning marijuana has been pro!en unsuccessful and

    had a lot of people who use cannabis despite the illegal status, then it is time to

    accept the fact that the legal regulation of marijuana would likely prohibit those

    under the influence of cannabis on dri!ing. %ith the enforcement of marijuana

    laws regulations6 time, energy, and funds the go!ernment to arrest those whouse cannabis are the responsibility of the home > not in a public place, could be

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    di!erted to allow the police to arrest the real offenders, including the dri!er who

    is under the influence of marijuana.

    3. 'ituation @ Conditions.

    Responsible cannabis users will be cautious in beha!ior, procedures, andregulate its use with either. "he situation" here refers to setting the !alues,

    attitudes, e+perience and personality, and "condition" here relates to the

    physical and social situation of the users of the marijuana. Responsible

    marijuana users will always be aware of the situation and condition, place, time,

    mood, etc. and did not hesitate to say "=

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    Countries in the 'orld thats een legali*e cannais

    ere is a list of the countries in the world that ha!e legalized marijuana

    possession.

    :. =etherlands * Cannabis can be bought and consumed directly in

    "Coffeshop," but sell and consume marijuana outside Coffeshop, illegal.

    'ince :AFB, the =etherlands has been a leader in reforming the =arcotics

    -ct to draw a clear distinction between soft drugs ?soft drugs and hea!y

    drugs ?hard drugs. 2arijuana into the mild narcotic and legal groups in

    limited Duantities.

    8. 9ermany *

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    :E.(elgium * -ccording to the law, adults can carry up to 3 gramganja.

    (elgium is one of the first countries to make perbedaanhukum between

    "4ossession of cannabis for personal use and other types of drug type of

    offense."

    ::.Czech Republic * 'ince 8E:E, possession of drugs and psychotropic

    already didekriminalisasi. (ecause according to the study, the =arcotics

    -ct tidakhanya increase pra!elensi drug use in the country, but also failed

    to stop the illicit trafficking of illicit drugs.

    :8.(razil * )ecriminalization of marijuana and drug decriminalization of

    personal untukkeperluan in place since 8EEB. &t is the result of =arcotics

    re!isiUU massi!ely in 8EEB.

    :3.Chile * Consuming marijuana in small amounts is allowed as long as it isdone in the home and alone.

    :/.Uruguay *

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    !n Cannais Com+ounds !nhiit Cancer

    Compounds found in marijuana is belie!ed by scientists United 'tates

    can stop the spread of breast cancer throughout the body.

    he team of "California 4acific 2edical Center Research &nstitute" hope thatcannabidiol or C() could be a non*to+ic alternati!e to chemotherapy.

    Unlike cannabis, C() does not ha!e the characteristics of psychoacti!e so that

    its use does not !iolate the law, the report of the "2olecular Cancer

    herapeutics".

    he author emphasizes that they do not ad!ise patients to smoke

    marijuana.

    hey add that it is !ery unlikely that effecti!e concentrations of C() could be

    reached by smoking cannabis.

    C() works by blocking the acti!ity of a gene called &d*: are belie!ed to beresponsible for the aggressi!e spread of cancer cells from the tumor site of

    origin * a process called metastasis. 4re!ious research has shown that C() can

    block aggressi!e human brain cancers. Recent research found that C()

    appeared to ha!e a similar effect on breast cancer in laboratory

    5 2arijuana Compounds hat Could elp Combat

    Cancer, -lzheimers, 4arkinsons ?&f

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    because they naturally occur in the marijuana plant.

    hats right. &n the eyes of the U' go!ernment, these non*psychotropic

    cannabinoids are as dangerous to consume as heroin and they possess absolutelyno therapeutic utility. &n the eyes of many scientists, howe!er, these

    cannabinoids may offer a safe and effecti!e way to combat some of the worlds

    most se!ere and hard*to*treat medical conditions. eres a closer look at some

    of these promising, yet illegal, plant compounds.

    Cannabidiol

    -fter C, C() is by far the most studied plant cannabinoid. Girst identified in

    :A/E ?though its specific chemical structure was not identified until :AB3,

    many researchers now describe C() as Duite possibly the most single important

    cannabinoid in the marijuana plant. hat is because C() is the cannabinoid that

    arguably possesses the greatest therapeutic potential.

    - key word search on the search engine 4ub2ed Central, the U.'. go!ernmentrepository for peer*re!iewed scientific research, re!eals o!er :,EEE papers

    pertaining to C() S with scientists interest in the plant compound increasing

    e+ponentially in recent years. &ts easy to understand why. - cursory re!iew of

    the literature indicates that C() holds the potential to treat dozens of serious

    and life*threatening conditions.

    T'tudies ha!e suggested a wide range of possible therapeutic effects of

    cannabidiol on se!eral conditions, including 4arkinsons disease, -lzheimers

    disease, cerebral ischemia, diabetes, rheumatoid arthritis, other inflammatory

    diseases, nausea and cancer. hat was theconclusionof researcher -ntonio

    Huardi, writing about C() in the (razilian Lournal of 4sychiatry in 8EE0. -

    8EEA literature re!iewpublished by a team of &talian and &sraeli in!estigators

    indicates that the substance likely holds e!en broader clinical potential. hey

    acknowledged that C() possesses an+iolytic, antipsychotic, antiepileptic,

    neuroprotecti!e, !asorela+ant, antispasmodic, anti*ischemic, anticancer,

    http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462008000300015&lng=en&nrm=iso&tlng=enhttp://www.ncbi.nlm.nih.gov/pubmed/19729208http://www.ncbi.nlm.nih.gov/pubmed/19729208http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462008000300015&lng=en&nrm=iso&tlng=en
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    antiemetic, antibacterial, antidiabetic, anti*inflammatory, and bone stimulating

    properties. 2artin ee, cofounder and director of the non*profit group 4roject

    C()S which identifies and promotes C()*rich strains of cannabis S agrees.

    Cannabidiol is Tthe Cinderella molecule, writes ee in his new book, 'moke'ignalsO - 'ocial istory of 2arijuana S 2edical, Recreational, and 'cientific

    ?'cribner, 8E:8. T#&ts$ the little substance that could. #&ts$ nonto+ic,

    nonpsychoacti!e, and multicapable.

    &ts also e+ceptionally safe for human consumption. -ccording to a just

    published clinical trialin the journal Current 4harmaceutical )esign, the oral

    administration of BEE mg of C() in :B subjects was associated with no acutebeha!ioral and physiological effects, such as increased heart rate or sedation.

    T&n healthy !olunteers, V C() has pro!en to be safe and well tolerated,

    authors affirmed. - 8E:: literature re!iewpublished in Current )rug 'afety

    similarly concluded that C() administration, e!en in doses of up to :,/5E

    milligrams per day, is non*to+ic, well tolerated, and safe for human

    consumption.

    ;et despite calls from !arious researchers to allow for clinical trials to assess the

    use of C() in the treatment of !arious ailments, includingbreast cancer, colon

    cancer,prostate cancer, and schizophrenia, a re!iew of the website S the online

    registry for federally supported federal trials worldwide S identifies only four

    U'*based clinical assessments of C(). wo of these are safety studies6 the

    other two are e!aluations of C()s potential to mitigate cra!ings for heroin and

    opiates. 'ati!e+, a pharmaceutically produced, patented oromucosal spraycontaining e+tracts of C and C(), is also undergoing testing in =orth

    -merica for use as a cancer pain relie!er under the name =abi+imols. he drug

    is already a!ailable by prescription in Canada, the United ingdom, and

    throughout much of Jurope for the treatment of !arious indications, including

    multiple sclerosis.

    4resently, howe!er, options for U' patients wishing to utilize C() are

    e+tremely limited. 2ost domestically grown strains of cannabis contain

    http://www.projectcbd.com/http://www.projectcbd.com/http://www.ncbi.nlm.nih.gov/pubmed/22716148http://www.ncbi.nlm.nih.gov/pubmed/22129319http://www.ncbi.nlm.nih.gov/pubmed/16728591http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339795/?tool=pubmedhttp://www.nature.com/tp/journal/v2/n3/full/tp201215a.htmlhttp://clinicaltrials.gov/http://www.gwpharm.com/sativex.aspxhttp://www.projectcbd.com/http://www.projectcbd.com/http://www.ncbi.nlm.nih.gov/pubmed/22716148http://www.ncbi.nlm.nih.gov/pubmed/22129319http://www.ncbi.nlm.nih.gov/pubmed/16728591http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pubmed/22231745http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339795/?tool=pubmedhttp://www.nature.com/tp/journal/v2/n3/full/tp201215a.htmlhttp://clinicaltrials.gov/http://www.gwpharm.com/sativex.aspx
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    relati!ely little C()and many smaller*sized cannabis dispensaries do not

    consistently carry such boutiDue !arieties. - handful of prominent cannabis

    dispensaries, mostly in California and Colorado, do carry C()*rich strains of

    cannabis or C()*infused products. owe!er, in recent months, se!eral of thesepro!iders, such as arborside ealth Center in

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    shown to promote anti*cancer acti!ity in malignant cell lines and to possess

    bone*stimulating properties. 2ore recently, a 8E:: preclinical trialreported that

    C(C influences ner!e endings abo!e the spine to modify sensations of pain.

    T#his$ compound might represent #a$ useful therapeutic agent with multiplemechanisms of action, the study concluded.

    Cannabigerol

    'imilar to C(C, cannabigerol ?C(9 also has been subject to relati!ely few

    scientific trials since its disco!ery in :AB/. o date, there e+ist only limited

    number of papers a!ailable referencing the substance S a keyword search on4ub2ed yields fewer than 55 citations S which has been documented to possess

    anti*cancer, anti*inflammatory, analgesic, and anti*bacterial properties.

    -ccording to a 8E:: re!iewpublished in the (ritish Lournal of 4harmacology,

    T#-$ whole plant e+tract of a C(9*chemotype V would seem to offer an

    e+cellent, safe new antiseptic agent for the treatment of multi*drug resistant

    bacteria. - more recent re!iewpublished this year in the journal 4harmacology

    @ herapeutics further acknowledges that C(9 and similar non*psychotropiccannabinoids Tact at a wide range of pharmacological targets and could

    potentially be utilized in the treatment of a wide range of central ner!ous system

    disorders, including epilepsy.

    etrahydrocannabi!arin

    )isco!ered in :AFE, tetrahydrocannabi!arin ?CK is most typically identified

    in 4akistani hashish and cannabis strains of southern -frican origin. )ependingon the dose, CK may either antagonize some of the therapeutic effects of

    C ?e.g., at low doses CK may repress appetite or promote them. ?igher

    doses of CK e+erting beneficial effects on bone formation and fracture

    healing in preclinical models, for e+ample. Unlike, C(), C(=, C(C, C(9,

    high doses of CK may also be mildly psychoacti!e ?but far less so than

    C.

    o date, fewer than 3E papers a!ailable on 4ub2ed specifically reference

    CK.

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    anticon!ulsant properties, as well as its ability to mitigate inflammation and

    pain S in particular, difficult*to*treat neuropathy.

    ike C(), CK is on the radar of (ritish biotech 9% 4harmaceuticals

    ?makers of 'ati!e+. -ccording to its website, the company has e+pressedinterest in the potential use of tetrahydrocannabi!arin in the treatment of

    obesity, diabetes and other related metabolic disorders. hough the compound

    has been subject to 4hase & clinical testing, a keyword search

    on clinicaltrials.go!yields no specific references to any ongoing studies at thistime.

    Low-dose vaporized cannabis signifcantly improvesneuropathic pain.

    %e conducted a double*blind, placebo*controlled, crosso!er study

    e!aluating the analgesic efficacy of !aporized cannabis in subjects, the majority

    of whom were e+periencing neuropathic pain despite traditional treatment.

    hirty*nine patients with central and peripheral neuropathic pain underwent a

    standardized procedure for inhaling medium*dose ?3.531, low*dose ?:.8A1,

    or placebo cannabis with the primary outcome being !isual analog scale pain

    intensity.

    4sychoacti!e side effects and neuropsychological performance were alsoe!aluated. 2i+ed*effects regression models demonstrated an analgesic response

    to !aporized cannabis. here was no significant difference between the 8 acti!e

    dose groupsN results ?4 X .F. he number needed to treat ?== to achie!e 3E1

    pain reduction was 3.8 for placebo !ersus low*dose, 8.A for placebo !ersus

    medium*dose, and 85 for medium* !ersus low*dose. -s these ==s are

    comparable to those of traditional neuropathic pain medications, cannabis has

    analgesic efficacy with the low dose being as effecti!e a pain relie!er as the

    medium dose.

    4sychoacti!e effects were minimal and well tolerated, and

    neuropsychological effects were of limited duration and readily re!ersible

    within : to 8 hours. Kaporized cannabis, e!en at low doses, may present an

    effecti!e option for patients with treatment*resistant neuropathic pain.

    PERSPECTIVE:

    he analgesia obtained from a low dose of delta*A*tetrahydrocannabinol

    ?:.8A1 in patients, most of whom were e+periencing neuropathic pain despite

    con!entional treatments, is a clinically significant outcome. &n general, the

    http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931567/?tool=pubmedhttp://www.gwpharm.com/Metabolic%20Disorders.aspxhttp://clinicaltrials.gov/http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931567/?tool=pubmedhttp://www.gwpharm.com/Metabolic%20Disorders.aspxhttp://clinicaltrials.gov/
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    effect sizes on cogniti!e testing were consistent with this minimal dose. -s a

    result, one might not anticipate a significant impact on daily functioning.

    Marijuana Lin,ed To %etter %rain unction !n

    %i+olar Patients

    Results from a new study show indicate that bipolar patients with a

    history of marijuana use ha!e better neurocogniti!e function than those who

    ha!e ne!er used cannabis.

    he team, from he Hucker illside ospital in 9len

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    e!aluations and completed a battery of tests measuring neurocogniti!e

    functioning.

    here were no significant differences between patients who used

    cannabis ?"suffered from CU)" and those who didnNt, regarding age, race, or

    education, the researchers wrote inPsychiatry Research.(ut, according to the

    researchers, patients with "Cannabis Use )isorder" were more likely to ha!e a

    history of psychosis than those who didnNt toke up, at 08 percent !ersus BF.3

    percent.

    (ut patients "with CU)" ?dammit, & mean pot smokers had significantly

    better attention, processing speed>set*shifting, and working memory than those

    without, putting the lie to the tired old stereotypes of "burnouts" and "stoners."

    "hese analyses indicate an interesting pattern suggesting superior

    neurocogniti!e performance among bipolar patients with comorbid CU) when

    compared to bipolar patients without a history of cannabis use," (raga and team

    concluded. "2oreo!er, this cogniti!e ad!antage is noted in spite of e!idence of

    a more se!ere clinical course."

    "%e hope that the results from this study will help guide and encourage future

    large studies and help further elucidate the multifaceted associations and

    possible impact of cannabis use in bipolar disorder," the researchers wrote

    Cannais Can .el+ in &l*heimers %attle

    -dd another link to the growing chain of studies showing that certain

    chemicals found in the cannabis plant can help -lzheimerNs patients.- study

    published earlier this year in the Lournal of -lzheimerNs )isease shows that C

    can slow or end the progress of the disease.

    (ut itNs more complicated than gi!ing patients a joint to toke ** though puffing

    apparently has itNs benefits as well. Researchers at the Uni!ersity of 'outh

    Glorida treated isolated -lzheimerNs cells in a lab with !arying amounts of C.

    he results show that C reduces or eliminates the protein buildup associated

    with the disease.

    -lzheimerNs attacks the brain by building up plaDues that cause

    inflammation. 2arijuana, coincidentally, has amazing anti*inflammatoryproperties.

    http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327http://www.ncbi.nlm.nih.gov/pubmed/25024327
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    "C is known to be a potent antio+idant with neuroprotecti!e properties, but

    this is the first report that the compound directly affects -lzheimerNs pathology

    by decreasing amyloid beta le!els, inhibiting its aggregation, and enhancing

    mitochondrial function," the studyNs lead author wrote in the journal. ")ecreased

    le!els of amyloid beta means less aggregation, which may protect against the

    progression of -lzheimerNs disease. 'ince C is a natural and relati!ely safe

    amyloid inhibitor, C or its analogs may help us de!elop an effecti!e

    treatment in the future."

    (ut e!en toking up regularly can help pre!ent the disease from taking

    hold, according to some studies. -n

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    kind used in the morning as an energy booster and treatment of other chronic

    diseases.

    Rick 'impson always make e+tracts of the type of strong &ndica, but

    cannabis &ndica dominant result of cross breeding it is 'ati!a can produce goode+tract. here are thousands of types of cannabis that has been repeatedly cross

    are married and each has a different effect on health. 'ome types of marijuana

    good for pain relief, while others return to control blood sugar le!els for

    diabetics or ocular pressure glaucoma patients.

    )osage and reatmentO

    ake e+tract :>3 the size of grain of rice and put it on the tip of the inde+

    finger. 4ut the e+tract at some point of the gums ?see illustration below.2o!ement of the tip of the inde+ finger slowly and circle until the e+tract was

    stuck in the gums. ift the finger and repeat the same process on the other

    gums. )o this until the e+tracts were stuck in the fingers disappeared.

    Remember that patients can use all parts of their gums to put e+tracts. %hen

    patients use false teeth, false teeth off the first and did as instructed abo!e.

    Cannabis e+tract is a powerful drugM 4atients should really understand

    this. -lways start treatment with the lowest dose ?:>3 grain of rice and

    gradually increase the dose until :gram per day. : gram dose is the dose

    reDuired to kill !arious diseases, especially cancer. &t takes appro+imately 5

    weeks until the patient is able to consume : gram of e+tract per day. %ith

    increasing dosage, the patient should be carefully di!iding the amount of e+tract

    consumed each day. 4atients should really take the time to find the dosage and

    how to use the right in this treatment.

    4atients can use the size of one big seed e+tract e!ery day as a precaution

    and maintaining a healthy body.

    ipsO

    4atients will reDuire adaptation time until the body is completely ready to

    recei!e this drug. J!eryone has a system adaptation is different, so patients

    really need to be sure and patient. 2ost patients reDuire 3*5 days of adaptation.

    &f carried out in accordance with the procedures, this treatment will not

    cause a sense of high ?euphoria. 2any patients do not feel the effects of the

    e+tract when you first use and then add the dose itself, conseDuently there is a

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    sense of euphoria at times une+pected. &f patients follow the instructions gi!en

    in the near future patients will feel small changes in e!eryday until finally

    reaching a healthy condition completely.

    (e sure to use cannabis e+tract in the morning. Lump*start with breakfast,brush teeth, mouth wash, and use the e+tract according the manufacturerNs

    instructions. -lways use the e+tract after eating and repeat these steps each time

    the patient wants to consume the e+tract. his pre!ents sticking cannabis e+tract

    in the lefto!ers and then attached to the teeth or swallowed into the stomach

    ?may cause high > euphoria.

    &ncreasing doses of the e+tract means increasing the freDuency of use,

    instead of adding a dose e!ery time wear. Gor e+ample, you are able to consume

    : rice seed e+tract e!ery day and wants to increase the dose to : Y grains of

    rice. ;our use of rice seed e+tract 8 Y times a day or eDual to taking one grain

    of rice e!ery day. o reach :Y grain rice, you only need to use the e+tract three

    times a day with the same dose. &f you want to increase the dose to 8 grains of

    rice a day, you eat four times a day6 and so on.

    : gram of e+tract daily dose is usually di!ided into 0*:E times

    consumption. his method is !ery helpful because it can create a system in the

    body of the patient remains stable.

    4atients should feel the changes that occur in the body. &f patients

    e+perience nausea, eating snacks and drinking water is sufficient to suppress it.

    &f allowed to occur, the patient may feel an+iety. &mmediately eat and drink

    water to o!ercome.

    %hen using cannabis e+tract, make sure the body of water consumed.

    -lthough patients do nothing, your metabolism will increase patient during

    e+tract react. 2ake sure there is water around the patient and drink immediatelyafter the patient urinated.

    4atients should consult with a health care professional if you want to use

    the e+tract and still under treatment6 especially with regard to blood pressure

    medication, pain and sleep. Remember to always drink water and li!e a healthy

    lifestyle.

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    C() protection against Jbola !irus

    here is good scientific e!idence that cannabis compounds in particular

    Cannabidiol the possibility to control the immune system and protection from

    !iral infection. Cannabis has been known as inhibitors of fungi and bacteria and

    is considered as a new class of antimicrobials for work differently from otherantimicrobials.

    Jbola is a !irus R=- comple+ organism that causes cells to "eat"

    pinocytosis #e!ents liDuid intake into the cell$ and then the !irus hijacks the cell

    to replicate itself. Replication in!ol!es can in!ol!e many mutations in the R=-

    code that would make it difficult if not impossible to make an effecti!e !accine.

    here is a U' patent that shows e!idence that the anti*!iral acti!ity of

    compounds.

    Usually the !irus*infected cells will produce a surface protein that is

    identified as a foreign body and the immune system will attack the cells were

    infected with this. Jbola !irus infection causes the cells to produce proteins that

    hide the !irus from the immune system. his mechanism allows the !iral R=-

    to hide the infected cells by the immune system to protect dr.

    he cause of death by this !irus is the immune system responds to the

    !irus in!eksi. his is the cause of mortality and morbidity from this in!eksi.

    Gurthermore, the !irus triggers the immune cells to release enzymes #cytokinesO

    a protein made by cells that affect the beha!ior of other cells$ that they hold.

    he release of this enzyme causes lymphocytes #a type of white blood cells in

    the immune system of !ertebrates being$ the other to release more cytokines.

    his process is also called a cytokine storm.

    'mall blood clots in the blood !essels of the so*called )&C #)isseminated

    &ntra!ascular Coagulation$ cause coagulopathy #blood clotting disorders or

    e+cessi!e bleeding$ where blood would not clot simultaneously with )&C#bleeding and clotting occurs at the same time$. 'ymptoms of shock against

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    to+ins #o+ic 'hock 'yndrome$ occurs when cytokines are released causing

    blood !essels to dilate in such a way.2arijuana compounds pro!en to reduce

    and pre!ent against to+ic shock and )&C ?8

    Jbola !irus also attacks the attachment of the cells caused by killer cellsimmune to release KJ9G #!ascular endothelial growth factorO signaling proteins

    produced by cells that menstimulasi!asculogenesis and angiogenesis. &t is part

    of a system that restores o+ygen supply to tissues when blood circulation is

    inadeDuate$ which resulted in the destruction of the tight relationship between

    the cells and lead to leaking of fluid between cells until bleeding.

    Cannabis compounds can inhibit KJ9G processes that occur in the

    relationship between cells.

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    * - method for treating diseases of the immune function that produces an

    infection such as 'imian &mmunodeficiency Kirus, Geline &mmunodeficiency

    Kirus, erpes 'imple+ !irus, Jpstein*(arr !irus, cytomegalo!irus, hepatitis (

    and C, influenza !irus, rhino!irus and in!eksimikrobakteri use Cannabidiol

    deri!ati!e claim 8

    * U' 4atent this, pro!ing that cannabis compounds to treat disorders of the

    immune system called a cytokine storm caused by different !iruses ?/

    * &n the description, the patent U' pro!ed that the regulation of the immune

    system may be the key to the sur!i!al of people with &K and can be applied to

    the sur!i!al of patients with Jbola. he process of direct lethal marijuana

    compounds #!irus infection$ pro!ed in &K infection ?/ but not on Jbola.

    owe!er, inhibition of KJ9G is essential to pre!ent leakage of endothelial

    #lining cells that line blood !essels and lymph, li!er, and other body ca!ities$

    and bleeding.

    (ecause marijuana is !ery safe to eat, especially under the super!ision of a

    doctor, the authors belie!e that snagat important for the medical community to

    begin human trials for the sake of the sur!i!al of the Jbola !irus sur!i!al

    regardless of political obstacles.

    ReferencesO

    : -ntibacterial Cannabinoids from Cannabis sati!aO - 'tructure * -cti!ity

    'tudy -ntibacterial Cannabinoids from Cannabis sati!aO - 'tructure * -cti!ity

    'tudy6 9io!anni -ppendino et al. he 'chool of 4harmacy, Uni!ersity of

    ondon

    8 4rotection -gainst 'eptic 'hock and 'uppression of umor =ecrosis Gactor Zand =itric

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    5 Curr 4harm )ecember 8EEB6 :8 ?8/O 3:35*/B. Cannabinoids, immune

    system and cytokine network. 2assi 4Kaccani -4arolaro ), Uni!ersity of

    &nsubria, Kia -. da 9iussano :E, 8:E58 (usto -rsizio ?K-, &taly

    B Cancer Res -ugust :5, 8EE/ B/6 5B:F Cannabinoids inhibit the KascularJndothelial 9rowth Gactor 4athway in 9liomas Cristina (l[zDuez

    ;4JR&= "httpO>>cancerres.aacrjournals.org>content>B/>:B>5B:F.full":,

    F ow Cannabis 2ight eep Coronary 'tents ...>how*cannabis*might*keep*coronary*stents*open*longer, Lune

    :E, 8E:/ )a!id -llen 2)