enzymes and biochemical reactions · 2018. 1. 31. · • enzymes are a type of protein that speed...
TRANSCRIPT
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Chemical Reactions• Chemical reactions = the breaking and creating
of bonds between different substances (this
requires energy)
• Activation energy = The amount of energy
needed to make a chemical reaction start
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Chemical Reactions• Reactants (substrate): substances that are
changed during a reaction
• Products: substances that are made by a
chemical reaction
reactants products
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Types of Reactions• Overall, reactions absorb or release energy.
• Endothermic: absorbs energy
• Ex. Photosynthesis
• Exothermic: releases energy
• Ex. Cellular Respiration
EXOTHERMICENDOTHERMIC
Less energy
in products
than reactants
More energy
in products
than reactants
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6CO2 + 6H2O C6H12O6 + 6O2
Photosynthesis
Energy is stored as sugar, therefore it is an
ENDOTHERMIC reaction
C6H12O6 + 6O2 6CO2 + 6H2O
Cellular Respiration
Energy is released as ATP when sugar is broken
down, therefore it is an EXOTHERMIC reaction
Key Biochemical Reactions
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• Enzymes are a type of PROTEIN that speed up biochemical reactions by lowering the activation energy.
– Because they speed up reactions, they are called catalysts.
• Enzymes are specialized molecules that bind to reactants (aka, substrate) and help to break or form bonds. Then they release a newly created product.
• Enzymes are not changed in a reaction and can be used over and over again!
Enzymes
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• Enzymes are very specific– They have an active site that fits only
one substrate (reactant)
– This is known as the lock and key model
Enzymes
enzyme
active site
substrate
(reactant)
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Enzymes
• Enzymes can break bonds in substrate to form two products
Substrate
enzyme
(Bonds breaking)
Products
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Enzymes• Enzymes can make bonds between substrates to
form one product
enzyme
Substrates
(Bonds forming)
Product
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Denaturation• Enzyme’s active site gets deformed and
loses its specific shape causes a loss of biological activity– Caused by: extreme changes in pH,
temperature, ion strength, and solubility
• Enzymes can be “renatured” to their original shape but not always
Normal enzyme Denatured enzyme
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1. Temperature = increasing temperature
increases the rate of the reaction
– Molecules are moving FASTER due to an
increase in kinetic energy, so they collide more
with each other
2. pH = how acidic a solution is
– Most enzymes only work at very specific pH so if
the pH changes it can affect speed of reaction
Ways to change the rate of a chemical reaction
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3. Substrate Concentration = the higher the amount of substrate, the faster the reaction– Due to more particle collisions
4. Catalysts = (like enzymes) speed up reactions – Lower activation energy needed for the reaction to
start
5. Competitive Inhibitor = slows down reaction
– Competes with substrate for the active site on the enzyme
Ways to change the rate of a chemical reaction