Department of Health and Human Services National Institutes of Health

National Center for Research ResourcesDivision of Research Infrastructure

Extending the Reach Extending the Reach

of Advanced Networking: of Advanced Networking:

Two Pilot Projects at the NCRRTwo Pilot Projects at the NCRR

Susan R. Kayar, Ph.D.

Shelia A. McClure, Ph.D. www.ncrr.nih.gov/resinfra.htmwww.ncrr.nih.gov/resinfra.htm

Institutional Development Award (IDeA)/DRI

Designed to enhance the competitiveness Designed to enhance the competitiveness for biomedical research funding of for biomedical research funding of institutions located in states with institutions located in states with historically low funding from NIH. historically low funding from NIH.

Inclusion of underserved populations is a Inclusion of underserved populations is a primary feature. primary feature.

Research focus is broad.Research focus is broad.

Eligible States

23 States and Puerto Rico

How is the Internet used at IDeA-Funded Institutions? CommunicationsCommunications

E-mail and basic computer servicesE-mail and basic computer services Library accessLibrary access Website design and utilizationWebsite design and utilization Video teleconferencingVideo teleconferencing

Genomics and Proteomics data managementGenomics and Proteomics data management ImagingImaging Equipment linking and collaboratoriesEquipment linking and collaboratories Data MiningData Mining Computing at high speed, high capacityComputing at high speed, high capacity Archiving of databasesArchiving of databases

““IDeANet” ProjectIDeANet” Project

Increased connectivity for high-bandwidth science Increased connectivity for high-bandwidth science applications in six western IDeA states is first step. applications in six western IDeA states is first step.

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Geographic Reality of Western Region IDeANet

Internet2 – ‘Abilene’ 10gb/s Upgrade

Connections to Backbone

U. Idaho

U. Wyoming

PNWGP

U. NevadaReno

Montana State U

CENICFRGP

U. Hawaii

U. Alaska

Multiple Levels of Benefit

IDeANet will relieve strategic bottlenecks in IDeANet will relieve strategic bottlenecks in connectivity entering states.connectivity entering states.

One major university campus per state to be One major university campus per state to be directly linked.directly linked.

In general, connectivity of on-campus and in-In general, connectivity of on-campus and in-state networks is relatively high.state networks is relatively high.

Many sites throughout states will experience Many sites throughout states will experience improved Internet performance.improved Internet performance.

Can leverage benefits to other university Can leverage benefits to other university departments and other institutions. departments and other institutions.

Additional Institutional Needs

End-to-end performance evaluation at all sites; Before/after performance metrics; Assessment of needs for computer configurations,

software, etc.; Address IT personnel issues (‘wizard gap’); Assess opportunities for achieving better

connectivity to other institutions in each state.

Research Centers in Minority Institutions (RCMI)

Designed to expand the Nation’s capacity for Designed to expand the Nation’s capacity for conducting biomedical research at institutions conducting biomedical research at institutions with 50% or greater enrollment of with 50% or greater enrollment of underrepresented minorities that grant doctoral underrepresented minorities that grant doctoral degrees in health/health-related sciences;degrees in health/health-related sciences;

Strengthen research environments and improve Strengthen research environments and improve faculty research competitiveness;faculty research competitiveness;

Enhance the clinical research capacityEnhance the clinical research capacity

How is the Internet used at RCMI Institutions ?

All the usual academic usesAll the usual academic uses Research training and faculty Research training and faculty

developmentdevelopment Bioinformatics and computational biologyBioinformatics and computational biology Research networks on health disparitiesResearch networks on health disparities Global collaborationsGlobal collaborations

RCMI Translational Research Network (RTRN) Goals:

Establish a stable high performance network linking Establish a stable high performance network linking RCMI sites and other sites (using Internet2 Abilene RCMI sites and other sites (using Internet2 Abilene infrastructure)infrastructure)

Establish distributed and linked data collections for the Establish distributed and linked data collections for the test bed clinical research projects test bed clinical research projects

Enable data mining from multiple data collections or Enable data mining from multiple data collections or databasesdatabases

Develop a stable software and hardware infrastructure Develop a stable software and hardware infrastructure with partnering groups that will allow centers to with partnering groups that will allow centers to coordinate efforts to accumulate larger studies than coordinate efforts to accumulate larger studies than can be carried out at one sitecan be carried out at one site

RCMI Translational Research Network (RTRN)

The RTRN will include:The RTRN will include: Consortium of clinical investigators from the RCMI Consortium of clinical investigators from the RCMI

Clinical Research Centers; Clinical Research Centers; Translational and clinical investigators from other Translational and clinical investigators from other

RCMI institutions as appropriate for studies; RCMI institutions as appropriate for studies; Other NIH-supported Clinical Research Centers; Other NIH-supported Clinical Research Centers; Other relevant organizations, including patient support Other relevant organizations, including patient support

organizations, for the study of a subgroup of diseases; organizations, for the study of a subgroup of diseases; and and

Data and Technology Coordinating Center (DTCC)Data and Technology Coordinating Center (DTCC)

RTRN - DTCC

The DTCC will provide : The DTCC will provide : Scalable coordinated clinical data management Scalable coordinated clinical data management

system for collection, storage, and analysis of system for collection, storage, and analysis of data of the RTRN data of the RTRN

Portal and tools for integration of developed and Portal and tools for integration of developed and publicly available datasets for data mining at publicly available datasets for data mining at RCMI CentersRCMI Centers

Web based recruitment and referralWeb based recruitment and referral User friendly resource site for the public, User friendly resource site for the public,

research scientists, and cliniciansresearch scientists, and clinicians

RTRN

This cooperative program should: This cooperative program should: facilitate identification of biomarkers for facilitate identification of biomarkers for

disease risk, disease severity/activity, and disease risk, disease severity/activity, and clinical outcomesclinical outcomes

encourage development of new approaches to encourage development of new approaches to diagnosis, prevention, and treatment of those diagnosis, prevention, and treatment of those diseases that disproportionately affect minority diseases that disproportionately affect minority populationspopulations