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Giving Effective Presentations Claus O. Wilke The University of Texas at Aus9n

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GivingEffectivePresentations

ClausO.WilkeTheUniversityofTexasatAus9n

Whycareaboutpresenta9ons?

WhatIwillcover

1.  Howtopresentanengagingstory2.  Designingslides:TheAsser9on–Evidencetemplate3.  Claus'petpeevesaboutpresenta9ons

1.Presentinganengagingstory:

TheOnionmodel

Let'sstartwithanexample.Abadone.

Ketogenic diet as supporting treatment option in glioblastoma multiformae

Ketogenic diet as supporting treatment option in glioblastoma multiformae

Onaketogenicdiet,theliverproducesketonebodies,inpar9cularβ-hydroxybuturate(BHB)

Ketogenic diet as supporting treatment option in glioblastoma multiformae

BHBcancrosstheblood-brainbarrierandserveasanalterna9vefuelforbraincells,replacingglucose

Ketogenic diet as supporting treatment option in glioblastoma multiformae

Adietisketogenicwhencarbohydrateintakefallsbelow20-50gram/daywhilefatcomprises~80%ofcaloricintake

Ketogenic diet as supporting treatment option in glioblastoma multiformae

Glioblastomamul9formae(GBM)needsglucoseforgrowth,andseemsinhibitedbythepresenceofBHB

Ketogenic diet as supporting treatment option in glioblastoma multiformae

SeveralclinicaltrialsarecurrentlyongoingtodeterminewhetherketogenicdietscansloworinhibitGBMgrowth

Didthisgetyouexcitedaboutketogenicdiets?

Why eating eggs and bacon may cure brain cancer

Why eating eggs and bacon may cure brain cancer

Canceristheleadingcauseofdeathindevelopedcountries

Why eating eggs and bacon may cure brain cancer

Despitemedicaladvances,mostcancertreatmentsaregruesomeyetonlymoderatelysuccessful

Why eating eggs and bacon may cure brain cancer

Ifwecouldpreventortreatcancerbyasimplechangeindiet,thatwouldbeawesome

Why eating eggs and bacon may cure brain cancer

Increasingevidencelinkscancertohigh-carbohydratediets(inpar9cularsugarandstarches)

Why eating eggs and bacon may cure brain cancer

Ea9ngahigh-fat,low-carbdiet(liketheAtkinsdiet)maystarvetumorsofnecessaryglucose

Why eating eggs and bacon may cure brain cancer

Ini9altrialswithbrain-cancerpa9entshavebeenpromising,andfurthertrialsareongoing

Didthisgetyoumoreexcited?

TheOnionmodel

TheOnionmodel

Why?

Thebigpicture:whyarewedoingthis,andwhydoesitma\er?

TheOnionmodel

Why?

What?

Relevantbackgroundfacts&

Whatwasdone?

TheOnionmodel

Why?

What?

How?

Minutedetailsofhowexactlytheworkwasdone

TheOnionmodel

Why?

What?

How?

Minutedetailsofhowexactlytheworkwasdone

Alwaysgofromtheoutsidein

Formaximumimpact,useapproximately

equalamountsoftimeforeachlayer

Why? ~30%oftalk

What? ~30%oftalk

How? ~30%oftalk(atmost)

Let'splacethecontentsofthedietslidesintotheonionframework

Ketogenic diet as supporting treatment option in glioblastoma multiformae

•  Onaketogenicdiet,theliverproducesketonebodies,inpar9cularβ-hydroxybuturate(BHB)

•  BHBcancrosstheblood-brainbarrierandserveasanalterna9vefuelforbraincells,replacingglucose

•  Adietisketogenicwhencarbohydrateintakefallsbelow20-50gram/daywhilefatcomprises~80%ofcaloricintake

•  Glioblastomamul9formae(GBM)needsglucoseforgrowth,andseemsinhibitedbythepresenceofBHB

•  SeveralclinicaltrialsarecurrentlyongoingtodeterminewhetherketogenicdietscansloworinhibitGBMgrowth

Why eating eggs and bacon may cure brain cancer

•  Canceristheleadingcauseofdeathindevelopedcountries

•  Despitemedicaladvances,mostcancertreatmentsaregruesomeyetonlymoderatelysuccessful

•  Ifwecouldpreventortreatcancerbyasimplechangeindiet,thatwouldbeawesome

•  Increasingevidencelinkscancertohigh-carbohydratediets(inpar9cularsugarandstarches)

•  Ea9ngahigh-fat,low-carbdiet(liketheAtkinsdiet)maystarvetumorsofnecessaryglucose

•  Ini9altrialswithbrain-cancerpa9entshavebeenpromising,andfurthertrialsareongoing

2.Designingslides:

TheAssertion–Evidencetemplate

Thetitleoftheslidemakesanassertion

Theslidebodyprovidestheevidencetosupporttheasser9on

Examples

Sequencingcostshavedeclined1000-fold

from2007to2010C

ost p

er g

enom

e

Year

Sep. 2007: $10,000,000

Sep. 2010: $10,000

Source: genome.gov/sequencingcosts

Violentcrimeisatanall-timelowH

omic

ides

/10

0,00

0 A

mer

ican

s

Year Source: http://blogs.berkeley.edu/2010/06/16/a-crime-puzzle-violent-crime-declines-in-america/

M&Mscomeinmanyfuncolors

3.Claus'petpeevesabout

presentations

Howtoruinatalkandputyour

audiencetosleepinoneslide

ClausO.WilkeTheUniversityofTexasatAus9n

Overview

•  Introduc9on•  Background•  Methods•  Results•  Conclusions

Overview

•  Introduc9on•  Background•  Methods•  Results•  Conclusions

Never!

GivingEffectivePresentations

ClausO.WilkeTheUniversityofTexasatAus9n

Whycareaboutpresenta9ons?

WhatIwillcover

1.  Howtopresentanengagingstory2.  Designingslides:TheAsser9on–Evidencetemplate3.  Claus'petpeevesaboutpresenta9ons

Claus'1stlawofpresenta9ons

Claus'1stlawofpresentations:

Alltextonslidesneedstobereadaloud

WhileIgenerallyprefergraphicalvisualiza9ons,insomecasestextispreferred.Forexample,summaryslidesoaenrequiresomeamountoftext.Textisfineaslongasyoureaditwordforword.Ifyoustartparaphrasingortalkingoveratext-heavyslide,however,youraudiencewillgetconfused.Theycannotatthesame9mereadthetextandlistentoyou.Someaudiencememberswillreadthetextandstoplistening.Otherswilllistenbutnotread.Allwillworrythattheymadethewrongchoiceandmissedsomethingimportant.

Nowanexampleofhownottodoit

Nowanexampleofhownottodoit.

Thisslideisfulloftext.Likely,noneofthetextma\ers,butyoucan'tknowforsureunlessyoureaditall.Butifyouwanttoreadit,youcan'tlistentomeblatheringonaboutsomethingcompletelydifferent.Thatisbecausehumanscannotprocesstwoseparatecontentstreams(visualandoral)atthesame9me.Nextweek'swinninglo\erynumberswillbe5,13,28,33,34,36,41.IknowbecauseI'ma9metravelerfromthefuture.

Whichstorylinewereyouabletofollow?

Important:The1stlawalsoappliestoslideswithgraphs!

Violentcrimeisatanall-timelowH

omic

ides

/10

0,00

0 A

mer

ican

s

Year Source: http://blogs.berkeley.edu/2010/06/16/a-crime-puzzle-violent-crime-declines-in-america/

Asmuchaspossible,avoidbulletpoints

The Department in numbers

•  We have 36 faculty members •  Annual grant funding: $5M

– Funding agencies: NSF, NIH, ARO, ONR, DARPA, DTRA, USDA

•  Our faculty members supervise 112 graduate students – 69 EEB, 23 Plant Biology, 10 CMB, 10 other

•  20% of our graduate students receive external fellowships – 14 NSF GRFP, 1 NIH F31, 10 other

The Department in numbers

36 faculty members

112 graduate students

69 EEB 23 PB 10 CMB 10 Other

20% students on external fellowships

14 NSF GRFP 1 NIH F31 10 Other

$5M annual grant funding

NSF, NIH, ARO, ONR, DARPA, DTRA, USDA

Usediagramsinsteadoftext

Analysispipeline

Kerretal.,J.Virol.2015

Builduptocomplex,many-facetedgraphs

Bindingtoancestordeclinesrapidlyinthe

controlscenario

Kachrooetal.,Science2015

Bindingtoancestordeclinesrapidlyinthe

controlscenario,butnotinWTscenario

Kachrooetal.,Science2015

Evenwithsubstantialdivergenceininterface

sites,evolvedproteinsbindancestors

Kachrooetal.,Science2015

divergenceininterfacesites

divergenceinnon-interfacesites

Paya\en9ontoyourbodylanguage

Slidebackgrounds:Whiteordark?

Advantagesofwhitebackgrounds

•  Easiertoworkwith(figures!)•  LookOkevenifprojectorisweak

Advantagesofdarkbackgrounds

•  Moreelegant•  Easierontheeye•  Goodwithphotos

SassodellaCroce,ValBadia,Italy

Butpleases9cktoonestyle,whiteorblack

Toavoidvisuallyshockingyouraudience

Summary

•  Tellastory•  Leadfromthewhy,thencoverthewhatandlimitthehow

•  Startthetalkstrong,forexamplewithaninteres9nganecdote

•  Usetheasser9on–evidencetemplate•  Don'tstartyourtalkwithaboringoverviewslide•  Whenyourslidescontaintext,readitout