iacuc procedures james weiland, phd professor of ophthalmology/bme iacuc chair [email protected]
TRANSCRIPT
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Agenda
• Who we are and what we do• First steps• Writing a good protocol• Process review
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IACUC
• People – Faculty, staff veterinarians, specialists (radiation, safety), and community members
• Role-– Review animal protocols to ensure that they
comply with the Guide (following Federal Law and NIH guidelines)
– Inspect animal facilities– Take corrective action for non-compliance issues
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First steps
• iacuc.usc.edu - > policies, FAQ, istar user guide• istar.usc.edu - > Obtain istar account, login for
protocol writing and maintenance• dar.usc.edu -> Training and services• With istar login, begin writing protocol• You must complete online, lecture, and hands-
on training for each species on a protocol prior to protocol approval
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Writing a good protocol
• START EARLY, CHECK DEADLINES (go to website)
• Read the question• Use lists, write concisely• Only provide detailed information once– Example – details of ketamine/xylazine anesthesia
are provided in species section 3, in other sections, simply state “ketamine/xylazine” without dosages
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Review Process
• Protocol submitted• In 2nd week of month (typically), pre-review meeting results
in “stipulations” to the protocol• PI has about 10 days to edit the protocol to address the
stipulations• At the Full Committee meeting (2 weeks after pre-review),
the protocol is recommended for approval, approval pending answers, not recommended for approval, deferred to next month
• Missing a submission deadline can delay review by a full month, so pay attention to the deadlines
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• Questions?