icohar 2019...by liza rosenbaum nielsen (dk) 11.30-12.15 presentations from selected abstracts ......

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FINAL PROGRAM ICOHAR 2019 16-18 April 2019, Utrecht, Netherlands

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Page 1: ICOHAR 2019...by Liza Rosenbaum Nielsen (DK) 11.30-12.15 Presentations from selected abstracts ... A2 2 A2 2 2 2 A 7 N230 Ring North / Maarssen 6 Utrecht-N Maarsseveense Plassen N’gein

F I N A L P R O G R A M

ICOHAR 201916-18 April 2019, Utrecht, Netherlands

Page 2: ICOHAR 2019...by Liza Rosenbaum Nielsen (DK) 11.30-12.15 Presentations from selected abstracts ... A2 2 A2 2 2 2 A 7 N230 Ring North / Maarssen 6 Utrecht-N Maarsseveense Plassen N’gein

ProgramDay 1 - Tuesday, 16 April 2019

Venue: Utrecht University Hall, Academic Building, Dom Square, Utrecht

15.00-19.00 registration

18.30-18.40 Welcome speech by Luca Guardabassi (DK/UK)

18.40-19.30 opening lectures Marc Sprenger (World Health Organization): One Health and AMR: taking stock 4 years after approval WHO Global Action Plan on AMR

Jorge Pinto Ferreira (World Organization for Animal Health): The OIE strategy on antimicrobial resistance

Welcome reception

Day 2 - Wednesday, 17 April 2019Venue: Jaarbeurs MeetUp, Jaarbeursplein, Utrecht (next to the Central station)

8.30-9.00 Keynote lecture by Jaap Wagenaar (NL): One Health in antimicrobial resistance: who should care?

room: Johan Friso Foyer room 117

9.00-9.45 one health integrated surveillance (organized by ESgarS) Chair: Arjana Tambic (CR)

Luis Martinez- Martinez (ES): Supranational Networks for surveillance of human multiresistant pathogens

Frank Møller Aarestrup (DK): The relative contribution by livestock to resistance problems in human medicine

New approaches for precision antimicrobial therapy (organized by EPaSg). Chair: P.L. Toutain (F)

Leonardo Pagani (I): PK/PD-driven antimicrobial therapy in ICU Alain Bousquet-Mélou (F): New approaches for precision antimicrobial therapy

9.45-10.30 mDr in mycobacteria and mycoplasma of human and animal origin (organized by ESgmYC and ESgmI).

Chair: Nir-Oaz Ran (IL) Miguel Viveiros (P): AMR in Tuberculosis and Non-Tuberculosis Mycobacteria:

a slow selective process in progress in One-Health, One-World Sabine Pereyre (F): Resistance and multi-drug resistance in mycoplasmas of

human and animal origin

The use of animal models for assessing antimicrobial impact on the gut microbiome (organized by ESgVm and ESgHamI).

Chair Ed J. Kuijper (NL) Hauke Smidt (NL): In vitro and animal models of the gut microbiome

Luis Pedro Coelho (ROC): The gut microbiome of dogs and cats shares genes and spe-cies with the human gut microbiome.

10.30-10.45 Coffee break

11.00-11.30 Invited lecture by Lloyd Reeve -Johnson (AUS): One Health and AMR: taking stock 4 years after approval WHO Global Action Plan in AMR

11.30-12.15 AMR in Clostridium difficile lineages shared by humans and animals (organized by ESgCD).

Chair: John Coia (DK) Maja Rupnik (SL): AMR and C. difficile from different reservoirs

Kate Dingle (UK): A role for tetracycline selection in recent evolution of the agriculture-associated C. difficile PCR-ribotype 078

Education on responsible antibiotic use in European medical and veterinary universities (organized by ESgaP).

Chair: Jeroen Schouten (NL) Carmen Espinosa Gongora (DK): Training the next generation of veterinary prescribers Oliver Dyar (S): Are we preparing medical students to prescribe antibiotics responsibly?

12.15-13.00 Zoonotic transfer of amr: the case of E. coli (organized by ESgmD). Chair: John W.A. Rossen (NL)

John WA Rossen (NL): Next generation sequencing: first diagnostic one-stop shop in one-health microbiology

Adrian Tett (IT): Cultivation-free detection and characterisation of pathogens by metagenomics

The impact of vaccination programmes on reduction of antimicrobial use (organized by EVaSg).

Chair: Johanna Fink-Gremmels (NL) Susanna Esposito (I): Impact of influenza and pneumococcal vaccines on antimicrobial

resistance Anders Fabio Antenucci (DK): How vaccination prevented an emerging E. coli

epidemic and antimicrobial overuse in the Scandinavian broiler production

13.00-14.00 Lunch break & Poster viewing

14.00-14.30 Invited lecture by Willem van Schaik (UK): The complex dynamics of antimicrobial resistance and microbiomes

room: Johan Friso Foyer room 117

14.30-15.15 The role of the environment in the spread of amr (organized by EFWISg).

Chair: Teresa Coque (SP) Luísa Vieira Peixe (P): Key players driving environmental emergence and

spread of AMR Johan Bengtsson-Palme (S): The environment and the antibiotic resistance

development – now and in the future

Nosocomial infections: a one Health perspective (organized by ESgNI). Chair: Margreet C. Vos (NL)

Laurent Poirel (CH): Emergence of acquired polymyxin resistance in Gram negatives; perfect example of a One-Health issue

Dorina Timofte (UK): Infection control in veterinary hospitals: why it matters

15.15-16.00 one Health issues related to amr in staphylococci (organized by ESgS). Chair: Jodi Lindsay (UK)

Francois Vandenesch (F): Antibiotic pollution as potential driving force of CA-MRSA expansion

Anette Loeffler (UK): MRSP carriage in dogs: A risk to people?

management of critically ill patients (organized by ESgCIP). Chair: David Dockrell (UK)

Jeroen Schouten (NL): The role of Antimicrobial stewardship programs in intensive care units

Joris Robben (NL): The challenge of infection control in a small animal intensive care unit

16.00-16.30 Coffee break

16.45-17.15 roundtable discussion on the lessons learned from emerging resistances in the past (e.g. VrE, ESBL, mrSa, carbapenem and colistin resistance). Chair: Patrick Butaye (B/SKN)

Participants: Lina Cavaco (DK), Laurent Poirel (F), Willem van Schaik (UK), Patricia Poeta (PT) and Youjun Feng (CN)

17.15-18.00 antimicrobial use guidelines for urinary and respiratory tract infections in human and veterinary medicine: a one Health perspective Invited lecture by Joseph Blondeau (CA) and Michael Lappin (USA)

18.00-18.30 Keynote lecture by Paul Flowers (UK): Antimicrobial resistance: a biopsychosocial problem requiring innovative interdisciplinary and imaginative interventions

18.30-20.00 Programme break

20.00-22.15 Social Dinner Stadskasteel Oudaen, Oudegracht 99, Utrecht

Page 3: ICOHAR 2019...by Liza Rosenbaum Nielsen (DK) 11.30-12.15 Presentations from selected abstracts ... A2 2 A2 2 2 2 A 7 N230 Ring North / Maarssen 6 Utrecht-N Maarsseveense Plassen N’gein

Program (continued)

Day 3 - Thursday, 18 April 2019Venue: Jaarbeurs MeetUp, Jaarbeursplein, Utrecht (next to the Central station)

8.30-9.00 Keynote lecture: Sensitive pathogen detection and rapid aST in the one Health future by Alex Van Belkum (F)

9.00-9.30 Invited lecture: antifungal use in veterinary practice and emergence of resistance. by Amir Seyedmousavi (International Society for Human and Animal Mycology)

9.30-10.00 Invited lecture: CBPs, ECoFFs, Intermediate, and all that jazz by John Turnidge (European Committee on Antimicrobial SusceptibilityTesting)

10.00-10.30 roundtable discussion on the future of antimicrobial susceptibility testing Chair: Luca Guardabassi (DK/UK);

participants: John Turnidge (EUCAST secretary), Peter Damborg (VetCAST chair), Hilde Moyaert (Animal Health Europe/Zoetis), Jordi Torren (European Medicines Agency) and Sakurako Marchand (bioMerieux)

Coffee break

11.00-11.30 Invited lecture: What can we learn from one Health evaluation of interdisciplinary amr research projects? by Liza Rosenbaum Nielsen (DK)

11.30-12.15 Presentations from selected abstracts

12.15-12.45 Closing keynote lecture: Alternatives to conventional antimicrobial agents: present and future by David Gally (UK)

12.45-13.00 Closing remarks by Johanna Fink-Gremmels (NL) and Ed J. Kuijper (NL)

13.00-13.30 Lunch package & refreshments

Important Information

opening Hours registration: Tuesday 16 April: 15.00 – 19.00 in the Utrecht University Hall, Academic Building, Dom SquareWednesday, 17 April: 8.00 – 12.00 in the Jaarbeurs MeetUp, Jaarbeursplein

It will be possible to register onsite: €250 for one day and €500 for the entire conference

CurrencyAll official prices are indicated in Euro (€). The official currency in The Netherlands is EURO (€). All major credit cards are accepted in most hotels, restaurants and shops.

InsuranceThe congress organisers cannot accept liability for personal injuries sustained, or for loss or damage of property belonging to conference participants, either during, or as a result of the meeting. Please check the validity of your own insurance.

LanguageThe congress language is English. Simultaneous translation will not be provided.

The ICoHar organizing Committee:

Prof. Luca gUarDaBaSSI (ESGVM)University of Copenhagen (DK) and Royal Veterinary College (UK)

Prof. Johanna FINK-grEmmELS (NCOH and EAVPT) Utrecht University (NL)

Prof. Patrick BUTAYE (ESGVM)Ross University School of Veterinary Medicine (SKN) & Ghent University (B)

Prof. Ed J. KUIJPEr (ESGHAMI and NCOH)Leiden University Medical Center (NL)

Page 4: ICOHAR 2019...by Liza Rosenbaum Nielsen (DK) 11.30-12.15 Presentations from selected abstracts ... A2 2 A2 2 2 2 A 7 N230 Ring North / Maarssen 6 Utrecht-N Maarsseveense Plassen N’gein

ESCMID (supporting organization)

bioMérieux (platinum sponsor)

Zoetis (supporter)

Sponsors

organization:

ICOHAR 2019 is supported by the European Society for Clinical Microbiology and Infectious diseases (ESCMID) and organized by the ESCMID Study Group for Veterinary Microbiology (ESGVM). As part of its mission, ESGVM promotes One Health by facilitating joint research and training collaborations between medical and veterinary microbiologists within areas of common interests, namely zoonoses and antimicrobial resistance. The event is organized in collaboration with other organizations:

The central theme of ESCMID Study Group for Host and Microbiota Interactions (ESGHAMI) focuses on clinical significance of and therapeutic interventions on host-microbiota associated diseases and health in both humans and animals.

AMR and One Health are priority topics for research and education at the Department of Veterinary and Animal Sciences of the University of Copenhagen. Among the various One Health activities, the Department coordinates a large multidisciplinary research center on control of AMR in people and animals (www.uc-care.ku.dk) and is involved in the organization of MSc course on AMR shared by veterinary and medical students.

The European Association of Veterinary Pharmacology and Toxicology (EAVPT) is the leading organisation of veterinarians active in the field of pharmacology and pharmacotherapuetics in Europe. The Association is strongly committed to the development of safe and effective therapeutics in the context of One health initiatives cognisant of the impact on animal, human and environmental health.

Edinburgh Infectious Diseases (EID) is the network of infectious disease researchers and clinicians in Edinburgh. AMR is a priority research topic for this network, which fosters infectious disease teaching and training at all levels within the University, including the development of a new MSc in One Health.

Netherlands Center for One Health aims for an integrated One Health approach to tackle the global risk of infectious diseases, and commits to create durable solutions for this major challenge by bundling world-leading academic top research in the Netherlands in the area of One Health.

The World Small Animal Veterinary Association (WSAVA)

Page 5: ICOHAR 2019...by Liza Rosenbaum Nielsen (DK) 11.30-12.15 Presentations from selected abstracts ... A2 2 A2 2 2 2 A 7 N230 Ring North / Maarssen 6 Utrecht-N Maarsseveense Plassen N’gein

Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

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Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

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towardsAmsterdam /Schiphol

towardsDen Haag /Rotterdam

towardsBreda / Maastricht

towardsDen Bosch

towardsArnhem

towardsAmersfoort

towardsHilversum

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Exitnumber 17 from this point 3 km (7 min) to P3 Jaarbeurs

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Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

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towardsAmsterdam /Schiphol

towardsDen Haag /Rotterdam

towardsBreda / Maastricht

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towardsArnhem

towardsAmersfoort

towardsHilversum

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Exitnumber 17 from this point 3 km (7 min) to P3 Jaarbeurs

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Media PlazaSupernova

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Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

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towardsDen Haag /Rotterdam

towardsBreda / Maastricht

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towardsAmersfoort

towardsHilversum

Exitnumber 8 from this point 2,2 km (4 min) to P1 and P Beatrixbuilding

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Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

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(fast) Tram

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Charging point

Parking for the disabled

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towardsAmsterdam /Schiphol

towardsDen Haag /Rotterdam

towardsBreda / Maastricht

towardsDen Bosch

towardsArnhem

towardsAmersfoort

towardsHilversum

Exitnumber 8 from this point 2,2 km (4 min) to P1 and P Beatrixbuilding

Exitnumber 17 from this point 3 km (7 min) to P3 Jaarbeurs

Truus

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Media PlazaSupernova

Exit P1 and Beatrixbuilding

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Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

Taxi

Bus

(fast) Tram

Information

Bicycle storage

Charging point

Parking for the disabled

Walking route Central Station

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towardsAmsterdam /Schiphol

towardsDen Haag /Rotterdam

towardsBreda / Maastricht

towardsDen Bosch

towardsArnhem

towardsAmersfoort

towardsHilversum

Exitnumber 8 from this point 2,2 km (4 min) to P1 and P Beatrixbuilding

Exitnumber 17 from this point 3 km (7 min) to P3 Jaarbeurs

Truus

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Exit P1 and Beatrixbuilding

Juliana

P3

Jaarbeurs Jaarbeursplein | 3521 AL Utrechtjaarbeurs.nl

Navigation adress Graadt van Roggenweg 400 | 3531 AH Utrecht030 295 59 11see on map

Congres halls complexHall 5 Congres halls Juliana I + IIUpstairs hall 7/8 CroesehallUpstairs hall 8 SupernovaUpstairs hall 9 Media Plaza

BeatrixbuildingJaarbeurs MeetUpBeatrix TheatreExpohallJIMTrade MartZeynOffices Jaarbeurs

Taxi

Bus

(fast) Tram

Information

Bicycle storage

Charging point

Parking for the disabled

Walking route Central Station

EHBO

ATM

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towardsAmsterdam /Schiphol

towardsDen Haag /Rotterdam

towardsBreda / Maastricht

towardsDen Bosch

towardsArnhem

towardsAmersfoort

towardsHilversum

Exitnumber 8 from this point 2,2 km (4 min) to P1 and P Beatrixbuilding

Exitnumber 17 from this point 3 km (7 min) to P3 Jaarbeurs

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Conference Venue

The Welcome reception on April 16th will be held at the Utrecht University Hall, Dom Square, in the historic city centre of Utrecht. The Academic Building is located directly next to the main Cathedral (The Dom).

The rest of the conference will be held at Jaarbeurs meetUp, Jaarbeursplein, Utrecht (see map below)

Navigation address: Graadt van Roggenweg 400 | 3531 AH Utrecht

www.icohar2019.org