WelcomeToTo

the World of Health and Innovation Leading to a Prosperity through

Chemical Sciences

Vision

About Us

Keminntek Laboratories is a Hyderabad (India) based Process R&D and

Contract Research Organization in Pharmaceutical sector in specific

Pharmaceutical Intermediates, Speciality Chemicals, Impurities etc.,

Our vision is to build Keminntek Laboratories into a world class leading

pharmaceutical service provider based on innovation while keeping health and

prosperity in mind. Imperatively, we will continue our business with high standards

of ethics in the interest of society and environment.

Vision

MissionWe are committed towards improving people’s health through science and

innovation. Our mission is to provide better access of affordable medicines to the

patients and positively impact prosperity.

Promoters of KeminntekName ofPromoter

Research Experience Chemistry Expertise

Dr.Srinivas KolupulaM.Sc.,Ph.D

-Ph. D in Chemistry (IICT-Hyderabad, India)-Postdoctoral Rresearch (3.0 years, France &Taiwan)-Assistant Professor(3.5 years, NIPER-Hyderabad, India)-Senior Scientist-III (2.5 years, USP – India, Hyderabad)

-Organic Synthesis -Drug Discovery-Peptido-mimetics-Impurity Synthesis-Fluorescent labeling agents;-Organic Materials -Heterocycles-Computational Chemistry– India, Hyderabad) -Computational Chemistry

Dr. G.C.M KondaiahM.Sc.,Ph.D

-Ph. D in Chemistry (SRMT, Nanded, India)-Hetero Drugs (1 year)-Dr. Reddy’s Labs(14+ years)

-Process Development /Tech. Pack-R & D to Validations @ Plant level;-DMF Filing/QbD (Non-Infringing )-IP Landscaping; Genotoxicity evaluation

Dr. SreenivasPeddolla

M.Sc.,Ph.D

-Ph. D in Chemistry ,OsmaniaUniversity, Hyderabad, India)-Laxai Avanti Life Sciences (2 years)Assistant Professor (3Years, Telangana University, India),-Visiting Faculty (University of Massachusetts, Amherst,MA, USA)

-Isolation of Natural products and preparation of semi-synthetic analogs,-Organic Synthesis-Preparation of Nanogels for targeted Drug Delivery-Heterocylic Chemistry

� Postdocs: 5 � Process R&D to DMF Filing

� Scale Up (multi-kg to MTs)

Team

Size Expertise

� Postdocs: 5

� Ph Ds: 5

�Masters: 20

� Process Engineer: 2

�Administrative staff: 8

� Supporting Staff: 10

� Scale Up (multi-kg to MTs)

� Impurity Synthesis

� CRO / Medicinal Chemistry

� Multi-step Organic Synthesis

� Critical Isolation/Purifications/

Crystallizations

� Cryo-reactions

� Genotoxic Evaluation

� Molecular Modelling

Research

Capabilities

mg to multi-kg

scale synthesis

Can Handle

Anhydrous Reactions

Multi-step organic

synthesis

Type & Scale of

Reactions

�Lithiation Reactions (n-BuLi)

�Bromination & other Halogenations

�Grignard Reactions

�High-Pressure Hydrogenations

�Amination Reactions

�Cryogenic Reactions etc.,

Capabilities Anhydrous Reactions

Can Execute Complex & Challenging Reactions

synthesis

• Advanced intermediates for Clinical Candidates

• Pharmaceutical Intermediates

• Key Starting Materials (KSM) for Pharma

• Pharmaceutical Impurities

• New Chemical Entities for Drug Discovery / DevelopmentType of Development

• Custom Synthesis of Speciality Products

• Fluorescent Labelling Agents

• Peptides/Peptido-mimetics

• Carbohydrates/Sugars

• Building Blocks / High-value Catalogue Chemicals

• Products related to Organic Materials / Agri-tech

• Nutraceuticals

Type of Products

Kilogram Scale Infrastructure

3200 sq. ft. Laboratory Space

All Glass Reactors -200L & 100L & 50L

Cryogenic Reaction Facility

Neutch Filter – 30L

Rotary evaporator – 20L

Fractional Distillation Setup – 50L

Power Back Up – 64 KV & 34KV

-20 °C Storage Facility

Long Columns (1.5 meter height)

Note: We have access to facilities (GMP& Non-GMP) with a capacity of

>300 KL reactors (including cryogenic reactors) for bulk production

8,000 sq. ft., Lab space

2,000 sq. ft., Ware house

Fume hoods/mL - 20L reaction setup

Vacuum/Fractional distillation set-up

Cold storage facility (-20 ºC)

ZLD facility

Green Practices

Emergency Exits

Fire ExtinguishersCold storage facility (-20 ºC)

Centralized Air Blowing facility

QMS (ISO 9001:2008 company)

Admin: HR/SCM/Accounts/Logistics

Biometric Attendance system

Surveillance Cameras (CCTV)

24 hours Security for the facility

Power Back up (64KV&34 KV)

Fire Extinguishers

Fire Hydrant System

Separate Solvent Yard

Aprons/Gloves/Masks

Safety Goggles/Shoes

Fire Blankets /Eye Washers

Analytical Instruments

•Shimadszu-LC-2010 CHT HPLC

•Shimadzu-LCMS-8030 Liquid Chromatograph Mass Spectrometer

•Shimadzu-GC- 2010 Plus Gas Chromatography•Shimadzu-GC- 2010 Plus Gas Chromatography

•PH meter Make: Polmon

•Analytical Balance Make: DenverAnalytical Department Team

•Y. Suresh - Manager

•Haneesha - Sr. Analyst

•Durga Rao - Sr. Analyst

•Rajesh - Jr. Officer

•Karunakar - Jr. Officer

Infrastructure Infrastructure

Why Why KeminntekKeminntek??

--Unique amalgam of expertise: Process R&D, CRAMS, Organic Synthesis, Medicinal Chemistry, Molecular Modeling etc.,

--Delivery of products with desired quality

--On-Time delivery / Rapid turn-around time

--Taking customer into confidence--Taking customer into confidence

--Competitive Pricing

--Maintaining the highest confidentiality

--Following GLP & maintains transparency

--We will be ready to negotiate penalty terms

--And Promoters are Young, Dynamic & Enthusiastic Pharma Professionals

NH

O

O

. HCl

CAS No: 220060-08-2

6

3 steps

L-Proline Derivative

Hi hl H i

Intermediates/KSMs on Bulk Scale

OO

O

O

1-(dimethoxymethyl)-2,4-dimethoxybenzene

CAS No: 91352-76-0

35kg scale

Purity: >99%MC: <0.5%

Highly Hygroscopic CAS No: 91352-76-0

~100kg scale

OR PO3R2RHN

N R

R

Complex Molecules

3 2RHNCOOR

10 steps

N

N NH

H2N

CH3

5 steps

O

NO

CAS No: 147356-78-3

Pharmaceutical Impurities

N

N

N

N

NN

N

HN

O

H

O O

N

N

N

N

NN

N

HN

O O

CH2OH

O

OH

HO OH

N

N

N

N

NN

N

NH

O O

NH2O

N N

NN

HN

O

N

N

NN

N

N N

O

O

HO2C

HN

S

O

CO2H

NH2

Cilastatin Impurity F

Linagliptin

N-Formyl Impurity Linagliptin

N-glucose Impurity

LinagliptinN-Acylamino Impurity

N

NN

O

LinaglitptinDimer Impurity

O

H

H H

N

AbirateroneEthyl Ether Impurity

O

H

H H

N

AbirateroneIsopropyl etherImpurity

Library of Molecules

ON

Br

NH2

Building BlocksBr

OBr Br

NH2

Cl

Co2H

Cl

Br

NH

O

O

O

N+O-O

N ClCl

NH2

H2N

NH

N

Br NH2

N CH3

NO2

O

N CH3Br

Trifluoromethyl building blocks

F

F

FNH2

OH.HCl

KEMINNTEK LABORATORIESPlot No. 10/11; Road No. 5,

IDA Nacharam, Hyderabad-500076, India

Tel: 091-9177846399 /9959700556Email: keminnteklabs@gmail.com

info@keminnteklabs.com

Website: www.keminnteklabs.com

Thank You