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Universidad Cooperativa de Colombia- Seccional MagdalenaFacultad de Ciencias de la Salud -Programa Cincias Bsicas Mdicas

Programa Medicina-rea Patologa, III Semestre-Aprendizaje Basado en Problema (ABP)

Caso 1-Hipertrofia del Miocardio

Caso 2-Hiperplasia Nodular de la Prstata

Caso 3-Metaplasia Escamosa , Pelvis Renal

Caso 4.-Metamorfosis Grasa Heptica

Caso 5. Atrofia de testculo

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Caso 1. Hipertrofia Cardiaca

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Caso 2. Hiperplasia de Prostata

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This kidney was removed from another autopsy patient who hadprostatic hyperplasia resulting in marked urinary retention andback-flow of urine from the bladder into the ureters and renalpelvis. The increased pressure inside the renal pelvis resulted indilation of the renal pelvis (1) and pressure atrophy of the cortex

(2). This change in the kidney is called hydronephrosis.

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Caso 3. Metaplasia Escamosa.NoPelvis Renal

This is a low-power photomicrograph showing the full cortical and medullarythickness of the kidney. Note that there is a dilated calyx containing some redblood cells in the center of the section (arrow). The cortex is markedly thin andhas severe lesions of degeneration and atrophy, although these are hard toappreciate at this low magnification.

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This gross photograph of liver tissue illustrates the yellowish

color of the liver parenchyma. The yellow color indicates high

fat content in this tissue. Compare this with the normal darkred color of liver.

Caso 4. Higado Graso

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This higher-power photomicrograph of the centrilobular area givesthe appearance of fatty tissue, as indicated by many empty spaces.

Very few normal liver cells can be seen in this slide. A few more

normal-appearing hepatocytes are present at the left portion of the

slide (arrows).

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An oil red O stain for fat was performed on a frozen section of

this liver tissue. The red droplets represent fat in the tissue

which is typical of fatty degeneration in the liver. By using

frozen sections the tissues do not have to be dehydrated

through alcohol solutions and thus the fat does not get

washed out.

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This photomicrograph of the liver is from another patient with ahistory of alcohol use. There are some clear vacuoles indicating

fat droplets (1) and there are numerous red-staining granular

deposits within the cytoplasm of hepatocytes (2)--this is alcoholic

hyalin. Alcoholic hyalin is easily distinguished from red blood cells

(3) that are also present in this section.

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This is a low-power photomicrograph of liver stained with a trichrome

stain. In this section, connective tissue stains green (arrows) and

hepatic parenchymal cells are red. Note that many of the

parenchymal cells have clear spaces indicating fatty degeneration.

The proliferation of scar tissue between the liver lobules is the result

of cirrhosis.

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This gross photograph of liver demonstrates severe nodular cirrhosis.

Note the extensive scarring of the capsule and the nodular projections

of tissue through the uncut capsule in this tissue. The green color is

due to the accumulation of bile pigment.

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This is a cut surface of the same tissue seen in the previous slide.

Note the marked nodular pattern. The paler-staining areas

between the round nodules represent fibrous connective tissue.

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Caso 5. Atrofia Testicular

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