media briefing saturday, april 16th 10:00 am – media briefing begins announcement of poster...
TRANSCRIPT
Media Briefing
Saturday, April 16th 10:00 am – Media briefing begins Announcement of poster winners and a short presentation
from some of the winning authorsIntroduction of Yehuda Handelsman, MD, FACP, FACE, FNLA
as the new President of AACE
10:25 am – Floor opens to questions from the media 10:30 am – Media Briefing adjourns
OMENTECTOMY ADDED TO ROUX-EN-Y GASTRIC BYPASS OMENTECTOMY ADDED TO ROUX-EN-Y GASTRIC BYPASS IMPROVES GLUCOSE AND ADIPOKINES AT 90 DAYS:IMPROVES GLUCOSE AND ADIPOKINES AT 90 DAYS:
A RANDOMIZED, CONTROLLED TRIALA RANDOMIZED, CONTROLLED TRIAL
TH Dillard1, JQ Purnell1, MD Smith2, J Laut2, W Raum2, D Hong3, E Patterson2
1.Department of Medicine, Division of Endocrinology, Diabetes, and Clinical Nutrition. Oregon Health & Science University, Portland, OR2.Department of Surgery, Legacy Good Samaritan Hospital, Portland, OR; 3.Department of Surgery, St. Joseph's Hospital, McMaster University, Hamilton, Ontario, Canada
AACE 2011AACE 2011
Coagulation abnormalities in Diabetes Mellitus type 2 and microvascular complications
Ritu Madan MD
Study design
Single center case control study between 2006-2008
60 patients with diabetes, 20 with and 40 without complications (nephropathy, retinopathy, neuropathy)
Equal number of males and females
Evaluation of major coagulation parameters
RESULTS
Results (contd.)
DM DM WITH COMPLICATIONS
P-value Significance
Platelet Count 1.93±0.60 2.06±0.62 0.43 NSPT 14.1±0.91 13.17±1.02 0.5 NSPTT 34.5±0.76 34.6±1.02 0.64 NSFibrinogen 239.5±36.7 259.37±40.85 0.07 NSAT III 95.8±14.71 95.82±10.89 0.99 NSProtein C 101.85±16.4 99.11±23.77 0.68 NSProtein S 63.05±16.85 51.59±10.7 0.002 SPAI-1 37.15±15.18 48.65±22.9 0.04 SvWF 123.19±29.63 155.57±34.61 0.007 SFactor V 98.65±3.43 98.7±4.39 0.9 NSFactor VIII 97.37±5.90 97.98±3.9 0.6 NSFactor IX 98.9±3.64 99.4±1.58 0.3 NS
Conclusions
Microvascular complications of Type-2 Diabetes are associated with changes in coagulation parameters.
Differences in coagulation parameters were seen in diabetics with complications of nephropathy and retinopathy compared to diabetics without these complications.
The magnitude of the coagulation abnormalities is unlikely to cause symptomatic thrombotic events and hence may be clinically silent.