meiosis in a nut shell

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    1903: Walter Sutton -

    American

    Studied Grasshoppers

    Sex Cells: 12

    Chromosomes

    Body (somatic cells):

    24 Chromosomes Observed the fusion of

    the egg and sperm cell

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    THEODOR BOVERIBOVERI SUTTON CHROMOSOMAL

    THEORY OF HEREDITARY

    1862 1915 - German

    Devised the same theoryusing sea urchins

    Discovered the centromere

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    A special form of cell division

    To form sex cells or gametes

    Occurs in Reproductive tissue of plants andanimals

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    PLANTS

    Male Cells: Pollen

    Formed in Anther Supported by Filament

    Anther and Filament formthe Stamen

    MALE PARTS OF PLANT

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    PLANT

    Female Cells: Ovules

    Formed in the ovary At the base of Style A Anther (Male) B Filament (Male)

    C Stigma (Female)

    D Style (Female) E Ovary (Female)

    FEMALE PARTS OF THE PLANT

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    MALE POLLEN CELLS FEMALE OVULE CELLS

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    MALE GAMETES (SEX CELLS) FEMALE GAMETES (SEX CELLS)

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    Chromosomes are made of DNA

    Genes are sections of DNA

    Most of the time DNA is in long strands calledthe Chromatin Network

    Just beforeMeiosis (andMitosis) the DNAreplicates then

    Coils to form a duplicated chromosome

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    Single Chromosome =5cm

    46 Chromosomes in ahuman body cell 10 000 000 000 000

    cells in the body

    10 Trillion cells or 1013

    Calculate the length Number of

    chromosomes x .005mx number of cells Comes to about

    2.0 1013 meters

    Which is about 67 tripsto the sun and back IN ONE HUMAN

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    Chromosomes occur in homologous pairs

    In humans 23 homologous pairs

    23 came from mother 23 came from father

    Total number is 46 Same characteristics are coded for on each

    pair E.g. eye colour

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    The DNA replicatesduring interphase

    The DNA coils To form a duplicated

    chromosome Two chromatid arms

    Joined by centromere Occur in pairs

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    ANIMALS

    Camel = 70

    House Fly = 18 Chicken = 78

    Chinchilla = 64

    Porcupine = 34

    Mosquito = 6

    PLANTS

    Rice = 24

    Beans = 22 Lettuce = 18

    Tomato = 24

    Apple = 34

    Pea = 14

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    DIPLOID CHROMOSOMENUMBER

    Somatic or body cells

    contain a diploid number ofchromosomes

    E.g. Humans 46

    HAPLOID CHROMOSOMENUMBER

    Sex cells or gametes

    contain a haploid numberof chromosomes

    E.g. Humans 23

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    MEIOSIS 1

    BeforeMeiosis DNAreplicates

    Start with one Diploid cell Formation of duplicated

    chromosomes Homologous pairs of

    duplicated chromosomesalign on equator (crossing

    over) Homologous pairs separate

    and go to each pole Cell divides into two 2 Haploid cells form Chromosome number halved

    MEIOSIS 2

    No replication of DNA

    Start with two HaploidCells Duplicated chromosomes

    align individually onequator

    Split at centromere Chromatid arms separate

    and go to each pole Each Cell divides into two 4 haploid cells form

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    INTERPHASE INTERPHASE

    Formation of proteins

    enzymes etc. needed forcell division

    Normal cell processes

    Duplication of DNA to formduplicated chromosomes.

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    PROPHASE OF MEIOSIS 1

    Chromosomes coil up Spindle forms

    Homologous pairs alignINDEPENDANTLY along cell equator Each homologous pair of

    chromosomes forms a tetrad Tetrad:two homologous

    chromosomes each made of two sisterchromatids

    Crossing over occurs

    Exchange of genetic (DNA) materialbetween non-sister chromatids Breaks in chromatids occurs at

    Chiasmata Homologous pairs no longer

    genetically identical

    PROPHASE OF MEIOSIS 1

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    METAPHASE 1

    Tetrads align on equator

    Aligned in homologouspairs

    Homologous pairs begin toseparate

    ANAPHASE 1

    Homologous pairs separate

    Duplicated chromosomesremain intact

    Each chromosome of ahomologous pair (tetrad)moves to the opposite pole

    of the cell Each new cell receives one

    chromosome from thehomologous pair

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    INTERPHASE

    Short interphase

    DNA re-coils to formduplicated chromosomes

    PROPHASE 2

    Spindle forms

    Duplicated chromosomesmove towards equator

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    METAPHASE 2

    Duplicated chromosomes

    align individually alongequator of cell

    Centromere on equator

    Chromatid arm either sideof equator

    ANAPHASE 2

    Centromere splits

    Chromatid arms move toopposite poles

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    TELOPHASE

    Nuclei reform

    Cytokinesis takes place Four haploid cells result

    SUMMARY

    Short interphase

    Duplicated chromosomesalign on equator of cell

    Split at centromere

    Move to opposite poles

    Cell division to form 4

    haploid cells

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    INDEPENDENT ASSORTMENT

    Each duplicated chromosome

    in a homologous pair canalign in two ways

    In humans 223 possibilities = 8million

    At fertilisation the possibility

    is 223

    x 223

    70 trillion (70 000 000 000)possible variations of humans

    BUT there is more

    CROSSING OVER

    2 to 3 crossing over events

    occur per chromosome Provides additional

    variation

    VARIATION is the rawmaterial for natural

    selection to act on Accumulated changes

    cause the process ofevolution

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