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NAME: P. K. (Chari) RANGACHARI UNIVERSITY ADDRESS: Professor (Emeritus) Medicine BHSc (Hons) Programme MDCL 3308 McMaster University Hamilton, ON Canada L8N 3Z5 DATE OF BIRTH: 15 January, 1943 CITIZENSHIP: Canadian DEGREES: M.B., B.S., Ph.D.

Medical Degree (M.B.B.S.), All India Institute of Medical Sciences, New Delhi (1965) Distinction in Pharmacology, Won the S.K. Dorab Tata Prize in Biochemistry. Won the Gold Medal as the best graduate of the year 1965.

Ph.D. in Pharmacology, University of Alberta, Edmonton in 1972. CURRENT STATUS: Professor (Emeritus) Medicine B.Hsc (Hons) Programme McMaster University Hamilton ONT L8N 3Z5

AWARDS:

1. President's Award for Excellence in Teaching (Educational Leadership), McMaster University, 1997

2. Ontario Confederation of University Faculty Associations Teaching Award, 1997

3. MSU (McMaster Students Union) Teaching Award, 2002

4. 3M National Teaching Fellowship , 2008

5. MSU (McMaster Students Union) Teaching Award, 2009

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6. Claude Bernard Distinguished Lecturer, American Physiological Society

April 2011

7. Nominated MSU (McMaster Students Union) Teaching Award , 2012

MEMBERSHIP OF EDITORIAL BOARDS:

1. Advances in Physiology Education

2. Biochemical and Molecular Biology Education

MEMBERSHIP OF SOCIETIES:

1. American Physiological Society

2. American Society of Pharmacology and Experimental Therapeutics (ASPET)

3. American Society for Biochemistry and Molecular Biology (ABSMB) 4. International Union of Pharmacology (IUPHAR)

Public Forums: Regular Participant in Radio Programmes (Canadian Broadcasting Corporation, CBC) mostly on literature and science.

RESEARCH EXPERIENCE/EMPLOYMENT HISTORY: 1. Demonstrator in Pharmacology in All India Institute of Medical Sciences, New

Delhi from January 1967 to August 1968. 2. Graduate Teaching/Research Assistant, from September 1968 to September

1979 at University of Alberta, Edmonton. Subsequently Fellow of the Medical Research Council, Canada (1970-1972).

3. Post-doctoral training at the Cardio-Vascular Research Institute, U.C. Medical Centre, San Francisco, with Dr. R. P. Durbin (1972-1974). Teaching Department Physiology, University of California, San Francisco.

4. At I.N.S.E.R.M. Unité 7, Hôpital Necker des Enfants Malades, Paris 75015. Initially as Attaché de Recherche, I.N.S.E.R.M. and subsequently as Boursier, Association de Claude Bernard (from 1974 to 1976).

5. At V.P. Chest Institute, Delhi University, Delhi, India (1976 to 1980) as Reader, Department of Pharmacology.

6. At Hôpital Bichat, Paris, France (1980 to 1981) as chercheur étranger with I.N.S.E.R.M. Unité 10 (service du Prof. Bonfils).

7. At McMaster University (1981-83), as a Fellow of the Canadian Heart Foundation in the Department of Neurosciences.

8. Research Associate, Department of Anatomy, Harvard Medical School and Department of Surgery, Beth Israel Hospital, Boston, Mass., U.S.A. (1983).

9. Associate Professor, Department of Medicine, McMaster University, 1984-1990.

10. Professor of Medicine, McMaster University, 1990- Dec 2003

11. Professor, Pharmacology and Therapeutics, Associate Director BHSc Program U

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Calgary, Dec 2003– Feb 2006

12. Professor (Emeritus) Medicine, BHSc (Hons) Program, Faculty Health Sciences, McMaster University, Hamilton, Ont. (since Feb 2006)

TEACHING A) AT McMASTER UNIVERSITY (1983-2003; 2006-present) (1) PROFESSIONAL PROGRAMMES (a) M.D. Undergraduate Programme

From 1983-2003, involved in teaching and administration (different roles) Tutored in multiple units (1,2,3,5) as well as co-chairing UNITs 1, 2 and 6. Currently tutor in Several Foundational units (MF2, 3,4)

(b) School of Nursing, Rehabilitation Sciences: Gave occasional lectures in pharmacology to students in both programmes

(2) UNDERGRADUATE PROGRAMMES (a) Honours Biology-Pharmacology Co-op Programme (from 1989-2003): From inception of the Programme, took over as Director (1992). Developed

several PBL courses (Introductory Pharmacology/Social Pharmacology

(b) Arts & Sciences Programme From 1989- 2003:

Designed Inquiry Courses (The Curing Society, Discovery)

From 2007-2009 Designed a first year course (Molecular Physiology) (c) Bachelor of Health Sciences (Hons) Programme Designed a 2nd year Inquiry course in Toxicology (Using Poisons)

Molecules in the Marketplace: 2 term Pharmacology course (3/4th years)

Inquiry Course (3rd Year): Teaching and Learning (3rd Year)

Inquiry course (3rd Year): Toxic tales (Toxicology and Creative Writing)

Inquiry Course (3rd Year) : Matters of Taste (Molecular Physiology of Taste Receptors and Culinary Practices)

(d) Other Involvements in Undergraduate Teaching: Designed an Interdisciplinary Course (Controversies in Health) which was open

to students from multiple faculties; tutors were drawn from multiple faculties as

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well. Supervised Students doing 4th year theses as well as independent courses.

Arts and Sciences Programme 1. Fraser, J. (1992): Alternative Health Care in Canada: Naturopathy in

Canada and its Struggle for Legitimacy. 2. Fitch, N. (1992) Technology Transfer in Health Care: a cost-effectiveness

study of curative and preventive technologies. 3. Seidler, C. (1994) Towards a male pill: An exploration into the context of

contraceptive research. 4. Ferguson, C. (1995) Community Health Care Centres as an alternative

form of health care delivery 5. Choi, S. (1996) Ideology of biomedical research 6. Singh, A. (1996) Intellectual property rights and the Neem tree 7. Clarke, J. (1996) The context of medical advice 8. Choi, N. (1999) Strategies to deal with antibiotic resistance: a

technological assessment 9. Khoshroshahi, B (2002) Towards a Culturally Sensitive Diagnostic

Scheme for ADHD in Turkey 10. Palmay, C (2002) Cross-Cultural Learning in Health Care 11. Avila, A.M. (2002) Exploring the Relationships between Culture and

Cognition and its implications for education 12. C. Ferguson (2009) The Evolution of the University.

Engineering and Society Programme Srokowski, E (2003) Health Care Facilities and the Natural Environment:

Options for Change Bachelor of Health Sciences (Hons) Programme (McMaster University) 1. N. Beilhartz (2008): The routes to Drug Approval in a global context 2. E. Baginska (2008): Marketing of Drugs—exploring Direct to Consumer

Advertising 3. A. Lebner (2008): An exploration of 18th and 19th century novels and the

portrayal of doctors and investigators 4. K. Kulasegaram (2009): Patient Perspectives on Tuberculosis

(3) INVOLVEMENT IN GRADUATE STUDIES: (i) Participated in the several graduate courses :

In 1991, developed MS760 a Problem-Based Graduate Course (The Physiological Basis of Pharmacology) Offered as two half-courses (A,B) each

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divided into two modules.

(ii) Coordinator for Physiology-Pharmacology Subsection of the Graduate/ Programme -Member Graduate Policy & Curriculum Committee

From July 1, 1988 to June 30, 1992.

(4) At U. Calgary (2004-2005) Responsible for Inquiry courses in an undergraduate B.HSc (HONS) Programme

Designed several courses (i) Lost in Translation—Exploration of Communications between scientists and the

Public (ii) The Social Life of Drugs`

(iii) The Social Life of Knowledge

Designed a Liberal Arts Course (the Poisoned Pen)

Chair (Liberal Arts and Sciences Committee)

Member (Inquiry Learning Action Group)

Member (LIDS)

(5) At Keele University (School of Pharmacy) 2010-2011 Offered two options to students: Teaching Meaningful or Meaningless? Examinations: Meaningful or Meaningless? EDUCATIONAL ACTIVITIES- BEYOND TEACHING ROLES External Committees-related to Teaching 1. Member Teaching Committee IUPHAR (International Union of Pharmacologists)

2. Member, Teaching Committee, ASPET (American Society Pharmacology Experimental Therapeutics)

3. Member, Teaching Committee, APS (American Physiological Society)

4. Editorial Board: Advances in Physiology Education, American Physiological Society

5. Editorial Board : Biochemistry and Molecular Biology Education (BAMBED)

OTHER EDUCATIONAL ACTIVITIES: Participation in Workshops and Conferences on Teaching 1. Chaired a session on Needs- Core content as part of the Spaulding Conference on

Renewal in Health Sciences held at McMaster University, 1987. 2. 1987, Visited University of Newcastle Medical School, New South Wales to

discuss problems of implementing the Iterative Loop Model in Unit 1. 3. Participated in faculty development as a tutor in the training workshops organised

by the Faculty Development (several times). 4. Participant - Workshop on teaching methods organised by IUPHAR, Amsterdam,

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1990.

5. Participant - Symposium on Problem-Based Learning organised by ASPET at Milwaukee, 1990.

6 Advisor - Workshops on Problem-Based Learning at U. West Indies (Jamaica, Guyana), 1991.

7. Participant - Workshop on teaching of physiology at Charles University, Prague, Czechoslovakia. 1991.

8. Organised a PBL Workshop at the Canadian Memorial Chiropractic College, Dec 1991

9. Participant - 12th Annual Conference on Teaching and Learning in Higher Education, York U. (Gave a demonstration of PBL in a Large Classroom Setting. 1992.

10. Participant - Workshop on teaching, York University, 1992.

11. Participated in Ontario Universities Show & Tell Conference (Guelph, 1990, 1991, 1992).

12. Organised a workshop at the Faculty of Pharmacy at U. Toronto (1992) and helped them develop a problem-based course for their D. Pharm. programme.

13. Organized workshop on Problem-Based Learning at the All-India Institute of Medical Sciences, New Delhi, India. July, 1992.

14. Participant in the First Congress of the African Association of Physiological Sciences, (participated in a workshop on the Teaching of Physiology) Nairobi, Kenya. September 1992.

15. Organised a Session on PBL for the members of the Engineering and Society Programme at McMaster University June 1993.

16. Participant in the 2nd Gauss Symposium on Medical Education, Munchen 1993 (EMITAC Session on Medical Education)

17. Participated in a Symposium on Self-Directed Learning at McMaster University.

18. (Presentation - Responsibility: The Rites of Privilege).

19. Organised a workshop on Teaching of Pharmacology at McMaster University, July 22-23, 1994 (Tricennial Conferences).

20. Organised a workshop at IUPHAR (Montreal), July, 1994. Quality Education in Pharmacology: The Affordable Options.

21. Participant, International Conference on Problem-based Learning in Higher Education, Linköping, Sweden. September 24-27, 1995.

22. Organised a workshop on Teaching Pharmacology, U.N.A.M., and Mexico City. November 15-18, 1995.

23. Invited speaker, Pedagogic Day organised by the Royal Danish School of Pharmacy, Copenhagen, Denmark. Also conducted 2-day workshop on Problem-based Learning. May 1996.

24. Conducted interactive session on Problem-based Learning at the University of Gothenburg, Sweden. May 1996.

25. Invited speaker, Department of Pharmacology at Marmara University, Istanbul, Turkey. November 1996

26. Invited speaker, Symposium on New Teaching Methods in Medicine at Istanbul University, Turkey. November 1996.

27. Plenary speaker, Conference on Problem-based Learning organised by the University of Delaware. Also conducted a workshop on Resolving Conflicts in the Tutorial Setting. June 1996.

28. Invited speaker, Harvard Medical School. February 1997.

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29. Guest Professor, Royal Danish School of Pharmacy. April-June 1997.

30. Interactive session on Problem-based Learning, University of Oslo. June 1997.

31. “Many Pathways to PBL” - presentation at the Panum Institute, Copenhagen. June 1997.

32. “Active Learning” - Presentation to Catalonian Pharmacological Society, Barcelona. June 1997.

33. Invited participant, symposium on “Principles of Student Centred Teaching and Assessment”, organised by Kobenhavn University, Elsinore Denmark. September 1997.

34. Participant, panel discussion on the topic “What are schools for?” on CBC Radio programme This Morning - The Sunday Edition. October 1997.

35. Invited speaker, 48th Annual Conference of the Canadian Society of Microbiologists, Guelph 1998. “Forays across borders: Various experiences in interdisciplinary learning” June 1998.

36. Invited speaker, 936th Conference, "PharNet: Establishing International Cooperation in Pharmacology Teaching on World Wide Web" organised by the Rockefeller Foundation. "The Old Teacher in the Brave New World: Between the Chalk and the Mouse". July 1998.

37. The Ideology of Research Publications. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston MA, 2000.

38. The Word is the Deed. University of Calgary, 2000.

39. The Inward Gaze. Plenary Talk at the Case Studies Conference, University of Buffalo, N.Y., October 2000.

40. Problem-based Learning: Thorns and Roses. Presentation at Experimental Biology 2001.

41. To Teach and to Learn: The Past as Prologue, Plenary Talk at PBL 2002: A Pathway to Better Learning, Baltimore, MD.

42. From Gunshot Wounds to Spiral Bugs: The Meandering Search for an Ulcer Cure. Public Lecture, Sigma Xi Society, University of New Mexico, May 2001.

43. Beyond Competencies: Room for Flair. Talk to Manchester's Medical School Sept. 2003.

44. The Dimensions of Active Teaching: Presentation at Symposium on PBL at Manchester University organized by British Pharmacological Society, Sept. 2003

45. Participant Teaching Workshop (Learning Commons), U. Calgary 2004

46. Speaker, Active Learning, U. Graz , Austria

47. Speaker, Symposium on Talking about Drugs to the Public (EB2005, San Diego)

48. Speaker, Teaching Pharmacology, at Canadian Therapeutics Congress, Vancouver, BC 2005

49. Speaker, ASPET symposium on Distance Education, San Francisco, EB 2006

50. Invited Speaker, Symposium on Teaching, IUBMB Kyoto, Japan, June 2006.

51. Invited Speaker, U. Keele, UK: “The Teacher’s Test: Not a One Day Game” May 2007

52. Invited Speaker, Hamilton Association for Advancement of Literature, Science and Art, Toxic Tales, October 2007

53. Invited Speaker, ASCEPT meeting, Adelaide, Australia, Dec 2007

53. Invited Speaker, U. Melbourne, Australia, Dec 2007

54. Invited Speaker, “The Power of Interactive Teaching: A Hands- On Workshop” at

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U. Minho, Braga, Portugal July 2008.

55. Invited Speaker , George Brown University, Toronto Feb 2009

56. Conducted Tutorials, Medical Students, Kuwait University , June 2009

57. Invited Participant/Speaker Active Learning and Graduate Course on Molecular Pharmacology, Karolinska University, Stockholm, Jan 2010/ Jan 2011 .

58. Conference on Medical Education, Plenary Speaker, Taiwan, October 2010 59. Gave the Claude Bernard Distinguished Lecture at EB 2011, Washington DC . 60. Plenary Speaker, Conference on Medical Humanities (The language of illness and Pain), at Birkbeck College, U. London, UK. July 2011 Organisation of symposia/workshops 1. Organised a Symposium for the International Union of Pharmacological Sciences

(IUPHAR) at Montreal, 1994 (Providing Quality Education in Pharmacology: The Affordable Options)

2. Organised a two-day Symposium at McMaster University as part of the Tricennial Celebrations (Pharmacologists for the future: Needs/Challenges/Responses), July 1994

3. Organised a Workshop on PBL at EB 2001 in Orlando, Fla

4. Organised a symposium (with J. Strandhoy) for ASPET (San Diego EB2003) Teaching Pharmacology to Diverse Audiences

5. Organised a Symposium for ASPET (San Diego EB2005): Talking about Drugs to the Public

6. Distance Education in Pharmacology (Symposium organised for ASPET San Francisco, EB 2006)

7. Organised Symposium on Teaching GI Physiology at EB2007, Washington DC

8. Organised Symposium on Student-Centred Learning in Health and Life Sciences, McMaster University (June 15-16, 2007)

9. Co-chair , Empowering Effective Teaching in Pharmacology for a Safer Tomorrow, Pre-Conference Satellite on Teaching Pharmacology, WORLD PHARMA 2010.

REVIEWED PAPERS FOR: 1. Biochem. Biophys. Acta

2. Can. J. Physiology Pharmacology

3. Am. J. Physiology

4. Life Sciences

5. J. Appl. Physiol.

6. Dig. Dis. Sciences

7. Gastroenterology

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8. Inflammopharmacology

9. Am. J. Nutrition

10. British Journal of Pharmacology

11. Journal of Pharmacology and Experimental Therapeutics

12. Advances in Physiology Education

13. International Journal of Cancer

14. Biochemistry and Molecular Biology Education.

EXTERNAL COMMITTEE MEMBERSHIPS: 1. Canadian Cystic Fibrosis Foundation

Member, Executive Committee Member, Research Committee

2. Associate Editor, Canadian Journal of Physiology and Pharmacology - 1992-95

3. Medical Research Council of Canada - Member Operating Grants Committee (Pharmacology and Toxicology) - 1992-1995

4. Medical Research Council of Canada - Scientific Officer, Operating Grants Committee (Pharmacology and Toxicology) - 1995-1999

5. Member of the Selection Committee for the Polanyi Prizes – 1996 - 1999

EXTERNAL EXAMINER

1. Ph.D. (McGill University)

2. Ph.D. (Queen's University)

3. Ph.D. (U. Toronto)

4. Medical Students (Kuwait University)

PUBLICATIONS: Publications on Educational Issues Refereed papers 1. Rangachari, P.K. (1988). Concerning the curriculum. Persp. Biol. Med. 31, 3,

369-380. 2. Rangachari, P.K. (1989) Simulated job interviews as learning devices. Acad.

Medicine, Aug. 438-439 3. Rangachari, P.K. (1991). Design of a problem-based undergraduate course in

Pharmacology: Implications for the teaching of physiology. Am.J.Physiol. 260 (Adv. Physiol. Educ. 5): S14-S21.

4. Rangachari, P.K. (1992). To teach and to learn: past as prologue (Letter). FASEB J. 6:2616

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5. Turpie, I.D., Bloch, R., Edwards, M., Rangachari, P., Patterson, C.J. and Tainsh, S.M. (1992). A Program to sensitise students to issues of geriatric care. Acad. Med. 67: 304-6.

6. Rangachari, P.K. (1993) A Portrait of Problem-Based Learning: Warts and All. Nigerian J. Physiol. Sciences 9:1-5.

7. Rangachari, P.K. (1994) Quality Education in Pharmacology: A Canadian Experiment Trends in Pharmacological Sciences 15: 211-214.

8. Rangachari, P.K. (1994) The Word is the Deed: The Ideology of the Research Article in Experimental Sciences. Am. J. Physiol. (Adv. Physiol. Educ.) 267:S120-S136.

9. Rangachari, P.K. (1994) The teaching of pharmacology: needs, challenges and responses for the future. Trends in Pharmacol. Sci. 15:399-402.

10. Rawnsley, K., Spaziani, R. and Rangachari, P.K. (1994) Evaluation in a problem-based course: contrasting views of students and teacher. Probe No. 12, p. 9-14.

11. Rangachari, P.K. (1995) Pharmacologists for the future. Pharmaceutical News 2 (1): 16-18.

12. Rangachari, P.K. (1995) A checklist to help students analyse published articles in basic medical sciences. Am. J. Physiol. (Adv. Physiol. Educ.13) 268: S21-S25.

13. Rangachari, P.K. (1995) Active learning: in context. Am. J. Physiol. (Adv. Physiol. Educ.13) 268:S75-S80.

14. Rangachari, P.K. and Crankshaw, D.J. (1996) Beyond facilitation: the active tutor in a problem-based course. Biochem.Ed. 24(4):192-195.

15. Rangachari, P.K. (1997) Basic Sciences in an Integrated Medical Curriculum: The case of Pharmacology. Adv. Health Sci. Educ. 2: 163-171.

16. Rangachari, P.K. (1997) Evidence-based medicine: old French wine with a new Canadian label. J. Roy. Soc. Med. 90(5): 280-284.

17. Rangachari, P.K. (2000) "Give us good measure": the basic medical sciences and the overloaded curriculum. Clin. Invest. Med. 23: 39-46.

18. Rangachari, P.K. (2000) Exploring the context of biomedical research through a problem-based course for undergraduate students. Adv. Physiol. Educ. 23: 40-51.

19. Rangachari, P.K. (2001) Problem-based learning at McMaster University: an inside view. Dolor 16:129-134.

20. Rangachari, P.K. (2001) Constructing Problems for PBL Course J. Med Education 5(4) 22-25

21. Rangachari, P.K. (2002) The TRIPSE: a process-oriented evaluation for problem-based learning courses in basic sciences. Biochem. Mol. Biol. Educ. 30: 57-60.

22. Rangachari, P.K. (2002) Student-designed Clinical Trials: Evaluating Self-directed Molecular Biology Education. 32(1) 3-6.

23. Rangachari, PK (2003) Poised Between the Pedantic and the Puerile: Physicians-to-be in a Problem-Based Learning Program. Biochemistry and Molecular Biology Education 31(3) 192-194.

24. Rangachari, P.K. (2004) Caring for Students: A Teacher's View. Biochemistry and Molecular Biology Education. 32(1) 3-6.

25. Rangachari, P.K. (2004) Exploring the context of drug use: a problem-based learning Schmiederbegs Arch Pharmacol, 369(2) 184-91.

27. Rangachari, P.K. (2004) The Targeted Oral Adv. Physiol. Educ. 28:213-214, 2004

28. Rangachari, P.K. (2004) Cite and Oversight, Drug Discovery Today 15; 9(22):954-6

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29. Rangachari, P.K. (2005) Evidence-Based Reference Letters? Biochem. Mol. Biol. Educ 33: 302-303.)

30. Rangachari, P.K. (2006) Lost in Translation?: Deconstructing Science in the News through an Inquiry-based course, Biochem. Mol. Biol. Educ 34(1), 5-11

31. Rangachari, P.K. (2006) Promoting Self-Directed Learning using a Menu of Assessment options: the Investment Model Adv Physiol Educ 30(4):181-94

32.

Rangachari, P.K. and Rangachari, U (2007) Information literacy in an inquiry course for first-year science undergraduates: a simplified 3C approach. Adv Physiol Educ. 2007 Jun; 31(2):176-9.

33. Rangachari, P.K. (2007) Texts in context: Horace Davenport, carbonic anhydrase, and gastric acid secretion. Adv Physiol Educ. 2007 Jun; 31(2):140-4.

34. Rangachari, P.K. (2007) Back to the future? Active learning of medical physiology in the 1900s. Adv Physiol Educ. 2007 Dec;31(4):283-7.

35. Rangachari P.K. (2007) Statistics: Not a Confidence Trick. A Commentary on “Guidelines for Reporting Statistics in Journals published by the American Physiological Society:the Sequel” Adv. Physiol Educ 31:300-301

36. Rangachari P.K. (2008) Of Tacit Knowledge, Texts and Thing-Based Learning (TBL) Biochem Mol Biol Education 36 (5) 363-364

37. Costa, M and Rangachari PK (2009) The Power of Interactive Teaching (Biochemical and Molecular Biology Education) 37, Issue 2, March/April 2009, 74-76

38. Rangachari P.K. (2010) Putting Students in Charge: A symposium on student-centred learning Teaching and Learning in Medicine 22 (02) 131-136

39. Rangachari, P.K. (2010) Teaching undergraduates the process of peer review: learning by doing. Adv. Physiol. Educ 34:137- 144 40. Rangachari , P.K. (2010) Of Toxic Tales and Poisoned Pens: Melding Toxicology and creative writing in an undergraduate course. Mol. Interventions 10 (6) 336-340 41. Rangachari, P.K. (2011) Steps to Pluripotent Learning: Provocative Teaching. Adv. Physiology Educ 35:323-9 42. Rangachari, P.K. (2011) Howard Barrows: An appreciation. Teaching and Learning in Medicine 23(4), 313–315 43. Toulouse, K, Spaziani and Rangachari, P.K. (2012) A Backward Glance, the Forward Gaze: Evaluation in Problem-Based Courses in Problem-Based Learning in Clinical Education: The Next Generation, edited Bridges, S., McGrath, C and Whitehill, T.L. Springer 44. Naji, F, Salci, L, Hoit, G and Rangachari P.K. (2012) The UNSIN Project: Exploring the molecular physiology of sins Adv. Physiol. Education 36:13-19 Publications not peer-reviewed (book chapters etc.) 1. Rangachari, P.K. (1991). Inequality of educational roles. Guest editorial,

Pedagogue vol 3 no 4, Winter 1992, p. 2.

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2. Rangachari, P.K. (1991). Purkyne, Pestalozzi and the teaching of physiology. Pedagogue. Vol.3. Summer, 5-6.

3. Rangachari, P.K. (1990). Student-centered contextual learning for undergraduates in science: a case report. Proc. Ontario Show & Tell Conf. p.111-118.

4. Rangachari, P.K. and Rosenfeld, J. (1991) The Group Triple Jump: A process-oriented examination for a problem-based course. Proc. 4th Instructional Show and Tell Conf. for Ontario Universities and Colleges. p. 103-106.

5. Rangachari, P.K. (1991) The Curing Society: Problem-based learning in a large group format. Proc. 4th Instructional Show and Tell Conf. for Ontario Universities and Colleges. p. 97-102.

6. Rangachari, P.K. and Crankshaw, D.J. (1992). Formative evaluation in a tutorial-based course. Proc. 5th Instructional Show & Tell Conf., U. Guelph. p. 125-131.

7. Bajcar, J., Winslade, N. and Rangachari, P.K. (1994) Formative Evaluations of Tutorial Performances in Two Problem-Based Courses. Proc. 7th Instructional Show & Tell Conference, Guelph. p. 9-10.

8. Rangachari, P.K. (1994) The Ruth Gales Scholars: High School Students in a Research Laboratory Proc. 7th Instructional Show & Tell Conference, Guelph. p. 95-97.

9. Rangachari, P.K., Williams, P.B., Crankshaw, D.J., Carpenter, J.R., Williams, D.W.,

10. Ebeigbe, A.B. and Omogbai, E.K.I. (1995) Providing quality education in pharmacology: the affordable options. In: Pharmacological Sciences: Perspectives for Research and Therapy in the Late 1990s (eds. A.C. Cuello and B. Collier). Birkhaüser Verlag, Basel.

11. Rangachari, P.K. (1996) Problem-based assessment: no easy way out. Proc.

12. Rangachari, P.K. (1996) Twenty Up: Problem-based Learning with a Large Group. In: Bringing Problem-Based Learning to Higher Education: Theory and Practice, ed. L.

13. Wilkerson & W.H. Gijselars. New Directions for Teaching and Learning vol. 68, Winter 1996, Jossey-Bass Publishers, San Francisco.

Book Reviews: 1. Rangachari, P.K. (1996) Review of David Clandfield, John Sivell, ed. and trans.,

Co- operative Learning and Social Change. Selected Writings of Célestin Freinet. Pedagogue 6, No. 3, Summer 1996.

2. Rangachari, P.K. (1996) Review of John Sivell, ed., Freinet Pedagogy: Theory and Practice. Pedagogue 7, No. 1, Winter 1996-97.

3. Rangachari, P.K. (1998) Review of Kay, L.E., The Molecular Vision of Life: Caltech, the Rockefeller Foundation and the Rise of the New Biology, and Rheinberger, H.-J., Toward a History of Epistemic Things: Synthesizing Proteins in the Test Tube. Am J Physiol (Adv .Physiol Educ) 19: S106-S108.

4. Rangachari, P.K. (2004) Review of T.Fenwick and J. Parsons The Art of Educational Evaluation: A Handbook for Educators and Trainers Adv. Physiol. Educ 28:120

5. Rangachari, P.K. (2009) Help at Hand (book review) Molecular Interventions 9: 263-264

6. Rangachari, P.K. (2010) Tuberculosis as Narrative (Book Review) , Molecular

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Interventions 10: 51-52

7. Rangachari ,P.K. (2011) Evidence-Based Sanctity (Book Review) , Molecular Interventions 11 (1) 53-54 Book 1. David, T.J., Patel, L., Burdett, K., Rangachari, P.K. (1999) Problem-based

learning in Medicine. Royal Society of Medicine, UK Dorsey, K.J., Rangachari, P.K. (2012) Students Matter: the rewards of university teaching, SIU Press, USA

Abstracts 1. Rangachari, P.K. (1993) Is an Integrated Curriculum possible? 2nd Gauss

Symposium, Munich, D.06:66. 2. Rangachari, P.K. The Case for Student-Centred Learning. IUPHAR, Montreal

1994 3. Rangachari, P.K. and Mierson,S. A Student-Exercise to teach critical analysis of

published articles in basic medical sciences. IUPHAR, Montreal 1994. 4. Rangachari, P.K. (1994) Design of a problem-based undergraduate course in

Pharmaco epidemiology. Canadian Pharmacoepid. Forum, 1994. 5. Rawnsley, K. Spaziani, R. and Rangachari, P.K. (1995) Evaluation in a problem-

based course: what teachers want, what students think. Proceedings of the International Conference on Problem-based Learning, Linköping University, Sweden 1995. p. 59

6. Rangachari, P.K. (1998) Forays across borders: Various experiences in interdisciplinary learning. CSM Guelph 1998.

7. Rangachari, P.K. (2000) The TRIPSE: A process-centred evaluation exercise for undergraduate problem-based courses in pharmacology. FASEB J. 14(8):A1572

8. Rangachari, P.K. (2002) The Dimensions of Active Teaching The Pharmacologist 44 :( 2) Supplement 1, p A 10

9. Nastos, S, Rangachari, P.K. (2008) The TRIPSE (Tri-Partite Problem-Solving Exercise) in a large class setting FASEB J. 22: 767.1

10. Rangachari, P.K., Nastos, S. (2010) Legacy TRIPSEs (Tri-Partite Problem-Solving Exercises): Fostering student engagement and learning in large classes. FASEB J 24: 633.1

EXPERIMENTAL RESEARCH: Research focus: Ion transport across both symmetrical and polarised cells, with a particular emphasis on the effects of inflammatory mediators (histamine, neuropeptides and eicosanoids) Experimental Research Publications Peer-Reviewed Publications 1. Rangachari, P.K. (1968). Subjective experiences of atropine poisoning. J. Indian

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Med. Ass. 51:34-35.

2. Rangachari, P.K., Paton, D.M. and Daniel, E.E. (1972). Aerobic and glycolytic support of sodium pumping and contraction in rat myometrium. Am. J. Physiol. 223(5):1009-1075.

3. Rangachari, P.K., Paton, D.M. and Daniel, E.E. (1972). Potassium-ATP ratios in smooth muscle. Biochem. Biophys. Acta. 274:462-465.

4. Rangachari, P.K., Daniel, E.E. and Paton, D.M. (1973). Regulation of cellular volume in rat myometrium. Biochem. Biophys. Acta. 323:297-308.

5. Rangachari, P.K. (1975). Histamine release by gastric stimulants. Nature 253:53-55.

6. Rangachari, P.K. (1975). Ba++ on the resting frog stomach: effects on electrical and secretory parameters. Am. J. Physiol. 228:511-517.

7. Rangachari, P.K. (1975). Ba++ on gastric stimulant: release of histamine. Am. J. Physiol.229:627-631.

8. Rangachari, P.K., Pernollet, M.G. and Worcel, M. (1976). Calcium uptake myometrial membranes: Effect of A23187, a calcium ionophore. Eur .J.Pharmacol. 40:291-294.

9. Rangachari, P.K. (1979). Acid secretion by isolated primate gastric mucosa. Am. J. Physiol. 236:E733-737.

10. Tripathi, S. and Rangachari, P.K. (1980). In vitro primate gastric mucosa: electrical characteristics. Am. J. Physiol. 239:G77-G83.

11. Rangachari, P.K., C.R. Triggle and E.E. Daniel (1982). Chloride removal selectively inhibits phasic contractions of guinea-pig ileal longitudinal smooth muscle. Can. J. Physiol. Pharmacol. 60:1741-1744.

12. Rangachari, P.K. (1983). Letter - Reply to Robinson. The Sodium Pump and its Rivals. Conflict resolution in Science. In: Perspectives Biol. Med. 26:510.

13. Grover, A.K., Kwan, C.Y., Rangachari, P.K. and Daniel, E.E. (1983). Na-Ca exchange in a smooth muscle plasma membrane enriched fraction. Am. J. Physiol. 244:C158-165.

14. Rangachari, P.K., Grover, A.K. and Daniel, E.E. (1983). Thallium uptake by canine iliac arteries. Hypertension 5:436-441.

15. Rangachari, P.K., Grover, A.K., Daniel, E.E. (1984). Effects of disulphonic stilbenes on Ca2+ transport in smooth muscle plasma membranes. Can. J. Physiol. Pharmacol. 62:1233-1238.

16. Rangachari, P.K. (1985). Estimates of Na+/K+ pumping in intact canine iliac arteries. Can. J. Physiol. Pharmacol. 63:101-106.

17. Soumarmon, A., Rangachari, P.K. and Lewin, M.J.M. (1984). Passive transport of Rb+ by hog gastric H+-K+-ATP-ase. J.Biol. Chem. 259:11861-11867.

18. Rangachari, P.K. and Matthews, J.B. (1985). Effect of Ag+ on isolated bullfrog gastric mucosa. Am. J. Physiol. 248 (Gastrointest. Liver Physiol. II):G443-449.

19. Matthews, J.B., Rangachari, P.K., Rowe, P.H., Lange, R., Marrone, G., Silen, W. (1985). Characteristics of sudden potential drop in frog gastric mucosa. Am. J. Physiol. 248 (Gastrointest. Liver Physiol. II):G587-593.

20. Rangachari, P.K. and McWade, D. (1985). Effects of tachykinins on the electrical activity of isolated canine tracheal epithelium: an exploratory study. Regulatory Peptides 12:9-19.

21. Grover, A.K., Singh, A.P., Rangachari, P.K., Nicholls, P. (1985). Ion movements in membrane vesicles: A new fluorescence method and application to Smooth Muscle. Am. J. Physiol. 248 (Cell Physical. 17):C372-C378.

22. Carverhill, P., Fox, J.E., McWade, D. and Rangachari, P.K. (1985). The Sodium

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pump in opossum vascular smooth muscle. Comp. Bioch. Physiol. 82A:621-625.

23. Rangachari, P.K., McWade, D. (1986). Ouabain-insensitive, halide-sensitive Tl+ uptake by canine iliac arteries. Biochem. Biophys. Acta 854:251-256.

24. Rangachari, P.K. and McWade, D. (1986). Epithelial and mucosal preparations of canine proximal colon in Ussing chambers: Comparison of Responses. Life Sciences 38:1641-1652.

25. Rangachari, P.K., McWade, D., Donoff, B. (1986). Prostaglandin responses on tracheal epithelium: Inhibition by TMB-8. Prostaglandins, Leukotrienes and Medicine, 25:49-50.

26. Rangachari, P.K., McWade, D. (1986). Peptides increase anion conductance of canine trachea: An effect on tight junctions. Bioch. Biophys. Acta. 863:305-308.

27. Rangachari, P.K., Triggle, C.R. (1986). Chloride removal and E.C. coupling in guinea-pig ileal smooth muscle. Can.J.Physiol.Pharmacol. 64:1521-1527.

28. Rangachari, P.K., McWade, D. (1987). Simultaneous measurements of 22Na and 36Cl in aqueous samples: A comparison of three different methods. Am.J.Physiol. 252:G436-438.

29. Rangachari, P.K., McWade, D. (1987). Histamine stimulation of canine colonic epithelium: potentiation by hydroxylamines. Eur.J.Pharm 135:331-335

30. Rangachari, P.K., McWade, D. and Donoff, B. (1987). Luminal tachykinin receptors on canine tracheal epithelium: functional subtyping. Reg. Peptides 18:101-108.

31. Rangachari, P.K., Donoff, B. and McWade, D. (1987). Effects of TMB-8, a calcium antagonist, on transport properties of the isolated canine tracheal epithelium. Bioch. Biophys. Acta, 905:311-319.

32. Rangachari, P.K. McWade, D., Donoff, B. (1988). Luminal receptors for bradykinin on the canine tracheal epithelium: functional subtyping. Reg.Peptides 21:237-244.

33. Keenan, C.M., Rangachari, P.K. (1989). Eicosanoid interactions in canine proximal colon. Am. J. Physiol. G673-679.

34. Rangachari, P.K., McWade, D. (1989). An "Epithelial" preparation from canine gastric mucosa: Effect of secretagogues. Am. J. Physiol. 257:G46-51.

35. Rangachari, P.K. (1990). Six pack balancing act: A conceptual model for the intestinal lining. Can.J.Gastroenterology 4:201-208.

36. Rangachari, P.K., Prior, T. and McWade, D. (1990). Epithelial and mucosal preparations from canine colon: responses to substance P. J.Pharm.Exp.Ther. 254:1076-1083.

37. DeBeaux, A., Keenan, C.M., Tytgat, K. and Rangachari, P.K. (1990). Responses of the colonic epithelium to auranofin: evidence for involvement of enteric nerves. J. Rheumatol. 17:1137-1141.

38. Rangachari, P.K., Donoff, B., Vavrek, R.J. and Stewart, J.M. (1990). Luminal responses to bradykinin on the isolated canine tracheal epithelium: effects of bradykinin antagonists. Reg. Peptides. 30:221-230.

39. Keenan, C.M. and Rangachari, P.K. (1991) Contrasting effects of PgE2 and PgD2: Ion transport in the canine proximal colon. Am.J.Physiol. 260:G481-G488.

40. Lad, R., Donoff, B. and Rangachari, P.K. (1991). Functional subtyping of muscarinic receptors in canine esophageal mucosa. Am.J.Physiol. 261:G464-G489.

41. Rangachari, P.K. (1991). Helicobacter and hypergastrinemia: The Quisling option. Scand.J. Gastroenterology. 26 Suppl. 187:85-90.

42. Rangachari, P.K. (1992). Histamine: mercurial messenger in the gut. (Editorial

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review) Am.J.Physiol. 262:G1-G13.

43. Rangachari, P.K., Prior, T., Bell, R.A. and Huynh, T. (1992). Histamine potentiation by hydroxylamines: structure-activity relations; inhibition of diamine oxidase. Am.J.Physiol. 263:G632-641

44. Rangachari, P.K., Prior, T. (1992). "Epithelial" preparations from the mammalian gut: responses to agonists, drugs and damaging agents. Exp. Clin. Gastroenterology 2:23-28.

45. Rangachari, P.K., Betti, P.A. (1993). Biological Activity of Metabolites of PGD2 on canine proximal colon. Am. J. Physiol. 264:G886-894

46. Rangachari, P.K., Berezin, M. Prior, T. (1993). Effects of bradykinin on the canine proximal colon. Reg. Peptides 46:511-522.

47. Muller, M.J., Prior, T., Hunt, R., Rangachari, P.K. (1993). H1 Contractile and H2 relaxant receptors in canine gastric muscularis mucosae. Life Sciences. 52:49-53

48. Crowther, R., Jukic, D., Regoli, D. and Rangachari, P.K. (1994) Functional Subtyping of Neurokinin Receptors on Canine Proximal Colonic Mucosa. J.Pharm. Exp. Ther. 268: 1374-1380.

49. Muller, M.J., Prior, T., Hunt, R.H. and Rangachari, P.K. (1994) Adenosine A1 receptors are not involved in contraction of canine gastric muscularis mucosae. Eur.J.Pharmacol.251: 151-156.

50. McKay, D.M., Ramage, J.R., Rangachari, P.K., Perdue, M.H. (1994) Effect of region, temperature and neuronal blockade on Na22 and 51Cr-EDTA movement across canine mucosae. Comp.Physiol.Biochem. 107A:711-717.

51. Rangachari, P.K. and Prior, T. (1994) Functional subtyping of histamine receptors in the canine proximal colonic mucosa. J. Pharm. Exp. Ther. 271:1016-1026.

52. Khan, I., LaPierre, N. and Rangachari, P.K. (1995) Messenger RNAs for neurokinin and histamine receptor subtypes in isolated canine colonic crypts. J. Pharm. Exp. Ther. 272:1285-1292.

53. Rangachari, P.K., Betti, P.-A., Prior, E.T. and Roberts, L.J., III. (1995) Effects of a selective DP receptor agonist (BW 245C) and antagonist (BW A868C) on the canine colonic epithelium: An argument for a different DP receptor? J. Pharm. Exp. Ther. 275:611-617.

54. Elmhurst, J.A., Betti, P.-A. and Rangachari, P.K. (1997) Intestinal effects of isoprostanes: evidence for involvement of prostanoid EP and TP receptors. J. Pharm. Exp. Ther. 282: 1198-1205.

55. Rangachari, P.K. (1998) The Fate of Released Histamine: Reception, Response and Termination. Yale J. Biol. Med. 71:173-82.

56. High, A., Prior, T., Bell, R.A., Rangachari, P.K (1999) Probing the "active site" of diamine oxidase: Structure-Activity Relations for Histamine Potentiation by O-alkylhydroxylamines on Colonic Epithelium. J. Pharm. Exp. Ther. 288:490-501.

57. Unmack, M.A., Rangachari, P.K. and Skadhauge, E. (2001) Effects of isoprostanes and prostanoids on porcine small intestine. J.Pharmacol. Exp. Ther. 296(2):434-441.

58. Sung, J.C., Rangachari, P.K. and Matthews, J.B. (2002) Opposing effects of PKCα and PKC ε on basolateral membrane dynamics in intestinal epithelium Am.J.Physiol Cell Physiol 283: C1548-1556

59. Larsen, P., Schleihauf E., Yu,H., Prior, T. and Rangachari, P.K. (2002) Ca and Sr stimulated short-circuit currents in the canine proximal colonic epithelium: Effects of DK-PGD2, a metabolite of prostaglandin D2 Can. J. Physiol. Pharmacol. 80(11): 1085-94.

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60. Crankshaw, D.J. and Rangachari, P.K. (2003) Isoprostanes: More than just mere markersMol. Cell. Biochem. 253:125-130

61. Prior, T., Hernandez, J. Tougas, G, Rangachari, P.K. (2004) Phenotypic differences in cholinergic responses of distal colonic epithelium Exp. Physiol 89.2 : 209-217

62. MacDonald, D., VanCrey, K., Harrison, P., Rangachari, P.K., Rosenfeld, J., Warren, C., and Sorger, G. (2004) Ascaridole – less infusions of Chenopodium ambrosioides contain a nematocide(s) that is (are) not toxic to mammalian smooth muscle. Journal of Ethnopharmacology. 92(2-3): 215-221.

63. Rangachari, P.K. (2005) A not so plain muscle: The maturing of smooth muscle research. Can. J. Physiol. Pharmacol. 83: 665-668.

64. Zarate N, Wang XY, White EJ, Boreham D, Rangachari PK, Huizinga JD (2006) Low doses of ionizing radiation can prevent radiation-induced colonic epithelial hypo responsiveness to muscarinic agonists Int. J. Radiat Biol 82(12) 887-98

65. Szewczyk MM, Davis KA, Samson SE, Simpson F, Rangachari PK, Grover AK (2007) Ca(2+) pumps and Na(2+) Ca(2+) exchangers in coronary artery endothelium versus smooth muscle. J. Cell Mol. Med 11(1) 129-38

Publications not peer-reviewed (book chapters, book reviews, letters, etc.) 1. Rangachari, P.K. (1976). Ba++ - an unusual stimulant of gastric acid secretion. In:

Gastric Hydrogen Ion Secretion. Edited by D. Kasbekar, G. Sachs and W. Rehm. Marcel Dekker, New York.

2. Worcel, M., Papadimitriou, A., Hamon, G. and Rangachari, P.K. (1976). Role of transmembrane Ca2+ movements and Ca2+ binding in the activation of rat uterus smooth muscle contraction. In: Smooth Muscle, Pharmacology and Physiology. Ed. Worcel, M. and Vassort, G., I.N.S.E.R.M., Paris.

3. Rangachari, P.K. (1978). B.B. Dikshit - his contributions to pharmacology. Ind. J. Pharm. Spl. Suppl.

4. angachari, P.K. (1978). Histamine as the final common mediator: the view from the fence. Acta Physiol. Scand. Suppl. S103:209-218.

5. oumarmon, A., Lewin, M.J.M. and Rangachari, P.K. (1980). An ATP-dependent Cl- transport system in gastric microsomes. In: Hydrogen Ion Transport in Epithelia. Edited I. Schulz et al. Elsevier North Holland.

6. Rangachari, P.K. (1980). Transport of substances across cell membranes. Chapter 3. In: Textbook of Biochemistry. Edited G.P. Talwar (Prentice Hall) p.22-33.

7. Lewin, M.J.M., Rangachari, P.K. and Soumarmon, A. (1981). Stimulus secretion coupling in the parietal cell. In Magen and Magen Krankheiten. Editors Domschke, Wormsley. Verlag N.Y. p.34-41.

8. Rangachari, P.K. (1985). Smooth Muscle Pharmacology - The Emergence of a Subdiscipline. in The Design of Smooth Muscle. Edited. P.K. Rangachari/A.K. Grover. Image Press, Hamilton p. I-11.

9. Rangachari, P.K., Grover, A.K. (1985). The Design of Smooth Muscle (Editors). Image Press, Hamilton.

10. Rangachari, P.K. and McWade, D. (1986). Peptides as promoters of paracellular permeability: A novel role for tachykinins? In Substance P and Neurokinins. Proc. Satellite Symp. XXX I.U.P.S. (Eds.) J. Henry et al. Springer-Verlag, N.Y. PP. 205-208.

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11. Rangachari, P.K. (1987). Fraud versus carelessness. Nature 326:736. (Letter)

12. Rangachari, P.K., McWade, D. (1988). Inflammatory mediators, enteric nerves and colonic transport: in Gastrointestinal & Hepatic Secretions: Mechanism and Control (ed. Davison, J.S., Shaffer E.A.). Chapt. 11:213-215. U. of Calgary Press, Calgary, Alberta.

13. Rangachari, P.K., Kean, W. (1989). Gold and D-penicillamine and the gastrointestinal tract in The Gut and Rheumatic Disease, ed. P.J. Rooney. Baillière's Clinical Rheumatology Vol 3:411-423, Baillière Tindall Lond.

14. Rangachari, P.K. (1991). Interpreting citations. FASEB J. 5: 2612. (Letter)

15. Rangachari, P.K. (1991). Effects of neuropeptides on intestinal ion transport. In: Neuropeptide Function in the Gastrointestinal Tract (ed. E.E. Daniel), CRC Press, pp. 429-446.

16. Rangachari, P.K., Prior, T. and Bell, R.A. (1995). Potentiation of intestinal secretory responses to histamine: pathophysiologic implications. In: Neuroendocrinology of Gastrointestinal Ulceration: Hans Selye Symposia on Neuroendocrinology and Stress. Volume 2, ed. S. Szabo, Y. Taché and G. Glavin, New York: Plenum Publishing Corp.

17. Rangachari, P.K. (1992). From Both Sides Now: The modulation of enterocyte function by contraluminal and luminal factors. In: Modern Concepts in Gastroenterology, Vol. III (eds. R. Fedorak, S. Collins and A. Thomson). 35-51.

18. Rangachari, P.K. (1992). Concerning prostaglandin D2: Forgotten, promiscuous, capricious. Ann. N.Y. Acad. Sci.

19. Rangachari, P.K., Muller, M.J., Prior, T. and Hunt, R.N. (1993). The canine gastric muscularis mucosae and acid secretion: A basket case? NATO Symposium on Acid Secretion (York).

20. Rangachari, P.K., Prior, T. and Bell, R.A. (1995). Potentiation of intestinal secretory responses to histamine: pathophysiologic implications. In: Neuroendocrinology of Gastrointestinal ulceration (eds. S. Szabo and Y. Taché). 25-32.

Abstracts 1. Rangachari, P.K., Khatter, J.C. and Friesen, A.J.D. (1969). Effect of stimulation on

acetylcholine content of a sympathetic ganglion. Proc.Can.Fedn.Biol.Soc. 12:5 2. Rangachari, P.K. and Paton, D.M. (1970). Metabolic requirement for spontaneous

contractions and ion movements in rat myometrium. Proc. Can. Fedn. Biol. Soc. 13:172

3. Rangachari, P.K., Paton, D.M. and Daniel, E.E. (1971). Effects of iodoacetic acid on contractility and ion movements in rat myometrium. Proc. Int. Cong. Physiol. Sciences 9:467

4. Rangachari, P.K. and Durbin, R.P. (1973). Effect of secretagogues and barium ion on resting frog stomach. Fed. Proc. 32:393

5. Rangachari, P.K. (1974). Ba2+ - an unusual stimulant of gastric acid secretion. Proc. Intl. Union. Physiol. Sciences 11:132

6. Rangachari, P.K. (1977). Histamine as the common mediator: A critical analysis. Upsala J. Med. Sci. 82(4):265

7. Tripathi, S. and Rangachari, P.K. (1978). Electrical properties of primate gastric mucosa. Ind. J. Pharm. Spl. Suppl. p.68

8. Rangachari, P.K., Soumarmon, A., and Lewin, M.J.M. (1981). Transport et recyclage du potassium dans la secrétion d'acide gastrique. In: Forum de

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Recherches gastroentérologiques clinique et biologique. Vol. 5:5A

9. Rangachari, P.K. and Grover, A.K. (1982) Anions and Stilbene derivatives: their effect on Ca2+ transport in smooth muscle plasma membranes. Proc. Can. Fed. iol. Soc. 25:159

10. Grover, A.K., Kwan, C.Y., Rangachari, P.K., Crankshaw, J. and Daniel, E.E. (1982). Na-Ca exchange by rat myometrium plasma membrane vesicles. Proc. Can. Fed. Biol. Soc. 25:162

11. Rangachari, P.K., Triggle, C.R. and Daniel, E.E. (1983). Agonist interactions and utilisation of calcium pools in the guinea-pig ileal longitudinal muscle. Fed. Proc. 42:1245

12. Triggle, C.R., Rangachari, P.K. and Daniel, E.E. (1983). Effects of total chloride substitution with isethionate on agonist responses in visceral smooth muscle. Proc. Canad. Fed. Biol. Soc. 26:

13. Rangachari, P.K. and Daniel, E.E. (1983). The Sodium Pump in Vascular Smooth Muscle. Biophys. J. 41:176a

14. Rangachari, P.K., A. Soumarmon and M.J.M. Lewin (1983). Cation transport by Hog gastric vesicles. Physiologist 26:A84.

15. Rangachari, P.K. (1984). C1- dependent transport systems across symmetrical and polarised cells. (Seven Cities Gut Club).

16. Rangachari, P.K. and Matthews, J.P. (1984). Effect of Ag+ on the isolated bullfrog gastric mucosa. Biophys. J. 45:140a

17. Matthews, J.B., Rangachari, P.K., Rowe, P.H., Lange, R., Marrone, G., Silen, W. (1984). Sudden potential drop (SPD) in gastric mucosa: possible relation to stress ulcer. Gastroenterology 86:177.

18. Matthews, J.B., Rangachari, P.K., Rowe, P.H., Starlinger, M. & Silen, W. (1984). Exchange diffusion and non-acidic chloride transport in bullfrog gastric mucosa. Physiologist 27:278.

19. Rangachari, P.K., Daniel, E.E. (1984). Estimates of Na+ pumping in intact arteries. Blood Vessels 21:198

20. Rangachari, P.K., McWade, D. (1984). Ouabain-insensitive, chloride-sensitive Tl+ uptake by canine iliac arteries. Physiologist 27:237

21. Grover, A.K., Singh, A.P., Rangachari, P.K., Nicholls, P. (1984). Smooth muscle plasma membrane vesicle ion permeability: A new method. Physiologist 27(h) p.237.

22. Rangachari, P.K., McWade, D., Belbeck, L. (1985). Estimates of sodium pumping ion canine mesenteric arteries following acute volume expansion. Proc. Can. Fed. Biol. Soc. 28:44

23. Rangachari, P.K., McWade, D. (1985). Cl- dependent transport systems across symmetrical and polarised cells. Clin.Invest.Med. 8:A105

24. Rangachari, P.K. and McWade, D. (1985). Substance P and related tachykinins on isolated canine tracheal epithelium. Biophys. J. 47:11a.

25. Rangachari, P.K., McWade, D. (1985). Epithelial and mucosal preparations of dog colon in Ussing chambers: Comparison of response to agonists. Physiologist 28:336

26. Rangachari, P.K. and McWade, D. (1986). Tachykinins on the isolated canine tracheal epithelium: an analysis of the "Dip". Biophys. J. 49:400a

27. McWade, D. and Rangachari, P.K. (1986). Colonic Transport: Evaluating neuronal contributions to inflammatory mediators. Gastroenterology 90:1547

28. Rangachari, P.K., McWade, D. (1986). Histamine and colonic transport: the neuronal contribution. Clin.Invest.Med.Suppl.

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29. Rangachari, P.K., McWade, D. (1987). Functional subtyping of the luminal tachykinin receptor on canine tracheal epithelium. Biophys. J. 345a.

30. Rangachari, P.K., McWade, D. (1987). A novel epithelial preparation from canine gastric mucosa: response to secretagogues. Fed. Proc. 46:1084.

31. Rangachari, P.K., McWade, D. (1987). Epithelial and mucosal preparations from the canine colon: responses to tachykinins. Fed. Proc. 46:1125.

32. Rangachari, P.K., McWade, D. (1987). "Epithelial" preparations from the gut: Responses to secretagogues. Proc. Xth Intl. Congress. PMCOL. Sydney 0.53

33. Rangachari, P.K., McWade, D. and Donoff, B. (1987). Tracheal epithelial responses to prostaglandins, cyclic nucleotides: inhibition by TMB-8 (an intracellular Ca2+ antagonist). Ped. Pulmonol., Suppl. 1:115.

34. White, C.M., Donoff, B. and Rangachari, P.K. (1987). Tracheal responses to eicosanoids, cyclic nucleotides and phosphodiesterase inhibitors: effects of TMB-8 (an intracellular calcium antagonist). Proc. 10th Int. CF Congress, Sydney: p55.

35. Rangachari, P.K. and Donoff, B. (1988). Luminal receptors for tachykinins on airway epithelia regional and interspecies variations. Reg. Peptides 22:151.

36. Rangachari, P.K. and McWade, D. (1988). Substance P responses on the canine colonic epithelium: direct and indirect effects. Reg. Peptides 22:152.

37. Rangachari, P.K., McWade, D. and Donoff, B. (1988). Luminal responses to substance P on rat trachea. Biophys.J. 53:522

38. de Beaux, A., Keenan, C.M., Tytgat, K. and Rangachari, P.K. (1988). Effect of gold salts on the canine colonic mucosa - Direct and indirect effects. The Physiologist 31:A142.

39. Rangachari, P.K., McWade, D. (1988). An "Epithelial" preparation from dog stomach: Responses to acidified aspirin (ASA) in vitro. Intl. Conf. Gastroenteric Biol., Chicago p.52.

40. Keenan, C.M., Rangachari, P.K. (1988). Eicosanoid interactions in the canine colon. Intl. Conf. Gastroenteric Biol., Chicago p.58.

41. Rangachari, P.K., Donoff, B., Vavrek, R.J., and Stewart, J.M. (1989). Luminal responses to bradykinin on the canine tracheal epithelium: Effects of BK antagonists. Biophys. J. 55:160a.

42. Rangachari, P.K., Prior, T., Bell, R.A. (1989). Effects of hydroxyl amines on histamine responses of the canine colonic epithelium: Structure activity relations. Dig.Dis.Sciences 34:1319

43. Rangachari, P.K., Prior, T., Muller, M.T., Hunt, R. (1989). Histamine on the canine colon: secreting and contractile effects. 2nd International Conf. Gastroenteric Biology, Chicago, IL.

44. Muller, M.J., Rangachari, P.K. and Hunt, R.H. (1990). Innervation of the canine corpus muscularis mucosae. Gastroenterology.

45. Muller, M.J., Rangachari, P.K. and Hunt, R.H. (1990). Histamine receptors in canine gastric and colonic muscularis mucosae. Gut 31:A1179-1180.

46. Keenan, C.M. and Rangachari, P.K. (1990). Contrasting effects of PgE2 and PgD2 in the canine proximal colon: a role for the "forgotten prostaglandin"? Dig.Dis.Sci. 35:1025.

47. Rosner, A. and Rangachari, P.K. (1992). Adenosine receptor subtypes in the canine colon. In: Neuro-Physiology of Gastric Mucosa.

48. Daley, S.J., Rangachari, P.K. and Stead, R.H. (1992). Compartmental analysis of nerve/mast cell associations in the canine colonic mucosa. In: Neuro-Physiology of Gastric Mucosa.

49. Muller, M.J., Donoff, B., Prior, T., Rangachari, P.K. and Hunt, R.H. (1992). Adenosine receptor-mediated contraction of canine gastric muscularis mucosae.

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Gastroenterology.

50. Muller, M.J., Donoff, B., Prior, T., Rangachari, P.K. and Hunt, R.H. (1992). The role of nitric oxide (NO) in non-adrenergic, non-cholinergic (NANC) relaxation in canine gastric muscularis mucosa. Gastroenterology

51. Betti, P.A. and Rangachari, P.K. (1992). Responses to prostaglandin D2 and its metabolites in canine colonic epithelium. Biophys.J. A536.

52. Rangachari, P.K., Betti, P.-A., Prior, E.T. and Roberts, L.J., II. (1994). Effects of PGD2 metabolites on canine colonic mucosa in vitro. 9th International Conference on Prostaglandins and Related Compounds, Florence, p.125.

53. Rangachari, P.K. (1998) Arachidonic acid metabolites: implications for intestinal pathophysiology. Z Gastroenterol 36:340.

54. Rangachari, P.K. (1998) Probing the “active site” of diamine oxidase: structure-activity relations for histamine potentiation by O-alkylhydroxylamines on colonic epithelium. Z Gastroenterol 36:341.

55. Unmack, M.A., Rangachari, P.K., Hansen M.B. and Skadhauge, E. (1998) Effects of isoprostanes and prostanoids on the short-circuit current in porcine small intestine in vitro. J Physiol 507.P:9P.

56. Larsen, P., Schleihauf, E., Yu, H.Y., Prior, T. and Rangachari, P.K. (2000) Ca stimulation of agonist primed canine colonic epithelium. FASEB J. 14(8):A1556. MT10633

57. Song,J.C., Rangachari, P.K. and Matthews, J.B. (2001) PKCα antagonizes PKCε-mediated cytoskeletal membrane remodeling: Role of basolateral Ca+ entry. Gastroenterology 120(5): A85.

58. Song,J.C., Rangachari,P.K., and Matthews,J.B. (2001) Ca+2-Dependent Cl- secretion in T84 epithelia: Role of SOCs and Na+-K+ ATPase. Gastroenterology 120(5):A527.

59. Prior, T., Hernandez, J., Rangachari, P.K., Tougas, G. (2002) Colonic mucosal response to cholinergic stimuli: are phenotypic differences important in the response to infection? Gastroenterology. ABS W968

60. Prior, T., Hernandez, J., Rangachari, P.K., Tougas, G. (2002) Altered colonic mucosal transport regulation and response to Trichinella spiralis in FSL and FRL rats. Gastroenterology. ABS W970.

61. Rangachari, P.K., Prior, T., Hernandez, J., Tougas, G. (2002) Differential effects of carbachol on distal colonic epithelium in Flinders rats. FASEB J 16(4): A458.

62. Rangachari, P.K. (2002) Benign Neglect: Georges Delrue and the isolated frog stomach. FASEB J. 16(4): A 384