necator americanus2
TRANSCRIPT
-
8/8/2019 Necator americanus2
1/15
Hookworm
Mohd Arif bin Ahmad Tharmiziarepahmad.blogspot.com
-
8/8/2019 Necator americanus2
2/15
Cause h ookworm diseaseNecat or species is f o und ov e r m uch o f thew este r n he m isphe r e, Af r ica and S o uth East AsiaCommo n h ookworm that infect m an
Necator americanus
Ancylostoma duodenaleLiv e in s m all intestine (habitat)Favor able c o nditi o ns f or the sp r ead o f infecti o n:
wa
rmte
mpe
ratu
res
Hum idityShadeCo nta m inati o n o f s o il w ith hu m an feces
N o Inte rm ediate h o st
-
8/8/2019 Necator americanus2
3/15
Hu mans a r e the o nly r ese rvo ir o f infecti o nfor N. americanus & A. duodenale
-
8/8/2019 Necator americanus2
4/15
AdultsCharacteristics Descrpitons
Look lik e Odd piece th r ead, ab o ut 1c m
Co lo ur White or light pin k ish
Size Fe m ale > m ale (usually)
Po ste r ior ends The m ale expanded t o form a Cop u latory B u rsa
Ante r ior ends ( Head) - Slightly bend (h ook ) and the mo uth ca rr ies cha r acte r isticteeth (plate)- No t r eal teeth but cuticula r form ati o ns o f the buccalcapsule
Sidev
iew
Side v ie w
Mo uth ca psule o f N ecator
americanus`
SEM
-
8/8/2019 Necator americanus2
5/15
Co pulat or y Bur sa
-
8/8/2019 Necator americanus2
6/15
R habditiform LarvaeImm atu r e: 270 x 15 mMatu r e: 540 x 700 m
Lo ng buccal ca v ity
Sm all genital p r imor diu m
-
8/8/2019 Necator americanus2
7/15
Filariform larvae700 m
Lo ng buccal ca v itySm all genital p r imor diu m
Lo ng es o phageusPo inted tail (bel ow )Infective stage
-
8/8/2019 Necator americanus2
8/15
EggsCharacteristics Descrpitons
Size 60 X 40 m
Shape O v al
Shell Thin & c o lo ur less
Co ntents 2-8 cells
-
8/8/2019 Necator americanus2
9/15
-
8/8/2019 Necator americanus2
10/15
Larval migrationDe rm atitis, k now n as "g ro und itch" or "st oo l
po iso n".The la rv ae penet r ating the s k in causealle r gic r eacti o n, petechiae or papule w ithitching and bu r ning sensati o n. Sc r atching leadst o sec o nda r y infecti o n
Pne u monitis (alle r gic r eacti o n)Lo effie r' s synd rom e: c o ugh, asth m a, l ow fe v e r,bioo d-tinged sputu m or he mo ptysis, chest-pain,infla mm ati o n shad ow s in lungs unde r X-r ayThese m anifestati o ns g o o n ab o ut 2 w ee k s.
-
8/8/2019 Necator americanus2
11/15
Adu
lts in small intestine(1) Epigast r ic pain as that o f a du o denal ulce r
(2) A la r ge worm bu r den r esults in m ic ro cytichyp o ch rom atic ane m ia (cha r acte r m anifestati o n).The sy m pt om s a r e lassitude, ede m a, palpitati o no f the hea r t. In se v e r e case, death m ay r esultfrom ca r diac failu r e or physical exhausti o n.
(3) All o t r io phagy ( or pica) is due t o the lac k o ft r ace ele m ent i ro n .
(4) A m en orr hea, ste r ility, ab or ti o nm ay ta k eplace in wom en.
(5) Gast ro intestinal bleeding(6) Infantile h ookworm disease
-
8/8/2019 Necator americanus2
12/15
Diagn o sis depends o n finding cha r acte r istic theeggs o n the st oo l:
Dir ect fecal fil m m eth o dFlo tati o n m eth o d
As the eggs o f both Ancylostoma & N ecator a r eindisting u ishable , t o identify the genus, theym ust be cu lt u red in the lab t o all ow la rv ae t o hatch o utRhabditif orm la rv ae hatching test
-
8/8/2019 Necator americanus2
13/15
-
8/8/2019 Necator americanus2
14/15
Wea r sh o esWor n w hen w al k ing in the a r eas w ith c ommo nhookworm disease
Mo nit or the disp o sal o f hu m ans feces
Albendaz o leMebedaz o le
-
8/8/2019 Necator americanus2
15/15