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Koo BMC Res Notes (2017) 10:46 DOI 10.1186/s13104-016-2371-1 RESEARCH ARTICLE A bibliometric analysis of two decades of aromatherapy research Malcolm Koo 1,2* Abstract Background: Quantitative data are lacking on the profile of published research in aromatherapy. The objective of the study was to investigate the profile of original and review articles under the topic aromatherapy using bibliometric analysis. Methods: Articles on aromatherapy, published between 1995 and 2014, were retrieved from the Science Citation Index-Expanded database from the Web of Science. The records extracted were analyzed for citation characteristics, including the distribution of publication years, languages, countries or regions, journals, articles, and authors using HistCite 12.03.17. VOSviewer v.1.61 was used to construct bibliometric diagrams. Results: A total of 549 original and review articles, published in 287 different peer-reviewed journals by 1888 authors, were identified. There was a steady increase in the number of published articles from 1995 to 2014. The majority of the articles was written in English (95.8%) and the United States was the leading country in the total number of published articles (n = 107, 19.5%) Journal of Alternative and Complementary Medicine published the greatest number of articles on the topic (n = 31, 5.6%). The article that received the greatest number of citations was published in Complementary Therapies in Medicine. Visualization analysis based on co-occurrences of words in the title and abstract revealed three clusters of research topics, including essential oil, intervention, and complementary medicine. Conclusions: This study provided a systematic overview of productivity and visibility of research work in aromather- apy and the findings could be used for organizing and prioritizing future research efforts in aromatherapy research. Keywords: Aromatherapy, Bibliometric analysis, Web of science database, Citation analysis, Scientometrics © The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/ publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Background Aromatherapy can be defined as a controlled use of aro- matic plant oils for therapeutic or preventive purposes. It can be applied through aerial diffusion, direct inhala- tion, and topical applications. e use of essential oils for therapeutic and spiritual purposes can be dated back to ancient civilizations, including the Chinese, Indians, Egyptians, Greeks, and Romans. However, the beginning of contemporary aromatherapy is often attributed to the pioneer work of the chemist René-Maurice Gattefossé and doctor Jean Valnet from the early twentieth century in France. It was not until the 1980s that aromatherapy became popular in the United States and began to gain attention for its potential clinical applications. Neverthe- less, despite its popular use in both the community and health care settings today [1, 2], there is still a paucity of empirical evidence supporting the efficacy of aroma- therapy in many therapeutic claims [3]. For example, systematic reviews indicated there are still limited evi- dence to support the effectiveness of aromatherapy in controlling stress [4], relieving labor pain [5], control- ling hypertension [6], reducing postoperative nausea and vomiting [7], and improving symptoms of dementia [8]. It is clear that more well-designed and implemented large-scale randomized controlled trials are needed to establish the efficacy of aromatherapy in these areas. In the meantime, analyzing the key journals, authors, and exploring the relationship of topical hotspots of aroma- therapy research may provide insight into the scope of Open Access BMC Research Notes *Correspondence: [email protected] 1 Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 2 Minsheng Road, Dalin, Chiayi 62247, Taiwan Full list of author information is available at the end of the article

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  • Koo BMC Res Notes (2017) 10:46 DOI 10.1186/s13104-016-2371-1

    RESEARCH ARTICLE

    A bibliometric analysis of two decades of aromatherapy researchMalcolm Koo1,2*

    Abstract Background: Quantitative data are lacking on the profile of published research in aromatherapy. The objective of the study was to investigate the profile of original and review articles under the topic aromatherapy using bibliometric analysis.

    Methods: Articles on aromatherapy, published between 1995 and 2014, were retrieved from the Science Citation Index-Expanded database from the Web of Science. The records extracted were analyzed for citation characteristics, including the distribution of publication years, languages, countries or regions, journals, articles, and authors using HistCite 12.03.17. VOSviewer v.1.61 was used to construct bibliometric diagrams.

    Results: A total of 549 original and review articles, published in 287 different peer-reviewed journals by 1888 authors, were identified. There was a steady increase in the number of published articles from 1995 to 2014. The majority of the articles was written in English (95.8%) and the United States was the leading country in the total number of published articles (n = 107, 19.5%) Journal of Alternative and Complementary Medicine published the greatest number of articles on the topic (n = 31, 5.6%). The article that received the greatest number of citations was published in Complementary Therapies in Medicine. Visualization analysis based on co-occurrences of words in the title and abstract revealed three clusters of research topics, including essential oil, intervention, and complementary medicine.

    Conclusions: This study provided a systematic overview of productivity and visibility of research work in aromather-apy and the findings could be used for organizing and prioritizing future research efforts in aromatherapy research.

    Keywords: Aromatherapy, Bibliometric analysis, Web of science database, Citation analysis, Scientometrics

    © The Author(s) 2017. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

    BackgroundAromatherapy can be defined as a controlled use of aro-matic plant oils for therapeutic or preventive purposes. It can be applied through aerial diffusion, direct inhala-tion, and topical applications. The use of essential oils for therapeutic and spiritual purposes can be dated back to ancient civilizations, including the Chinese, Indians, Egyptians, Greeks, and Romans. However, the beginning of contemporary aromatherapy is often attributed to the pioneer work of the chemist René-Maurice Gattefossé and doctor Jean Valnet from the early twentieth century in France. It was not until the 1980s that aromatherapy

    became popular in the United States and began to gain attention for its potential clinical applications. Neverthe-less, despite its popular use in both the community and health care settings today [1, 2], there is still a paucity of empirical evidence supporting the efficacy of aroma-therapy in many therapeutic claims [3]. For example, systematic reviews indicated there are still limited evi-dence to support the effectiveness of aromatherapy in controlling stress [4], relieving labor pain [5], control-ling hypertension [6], reducing postoperative nausea and vomiting [7], and improving symptoms of dementia [8]. It is clear that more well-designed and implemented large-scale randomized controlled trials are needed to establish the efficacy of aromatherapy in these areas. In the meantime, analyzing the key journals, authors, and exploring the relationship of topical hotspots of aroma-therapy research may provide insight into the scope of

    Open Access

    BMC Research Notes

    *Correspondence: [email protected] 1 Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 2 Minsheng Road, Dalin, Chiayi 62247, TaiwanFull list of author information is available at the end of the article

    http://orcid.org/0000-0002-9242-9167http://creativecommons.org/licenses/by/4.0/http://creativecommons.org/publicdomain/zero/1.0/http://creativecommons.org/publicdomain/zero/1.0/http://crossmark.crossref.org/dialog/?doi=10.1186/s13104-016-2371-1&domain=pdf

  • Page 2 of 9Koo BMC Res Notes (2017) 10:46

    aromatherapy research and help researchers to establish research priorities.

    Bibliometric analysis is a useful methodology for inves-tigating publication patterns based on citation data of academic literature. Bibliometric methods historically have been used to explore relationships among academic journal citations and to provide insight into the dissemi-nation of research findings. A well-known example of citation index is the Science Citation Index established by Eugene Garfield in 1964 [9]. With the wide availability of bibliometric analytical software, there is a rapid prolif-eration of bibliometric studies on various medical topics in recent years. For example, bibliometric analyses have been utilized to profile the trend of research on various diseases or interventions [10, 11], to quantify a country’s scientific output [12], to gain an insight into the changes in performance over time in a particular area of research [13], to identify highly cited publication [14] and their characteristics [15], and to explore the hot topics of research in a given field [16].

    Bibliometric methods have also been applied in com-plementary medicine research. Vickers used Medline database to determine a number of features of rand-omized trials in complementary medicine, including the extent to which they are indexed, the journals in which they are published, dates of publication, and the thera-pies and conditions studied [17]. More recently, Cramer and colleagues reviewed the bibliometric characteristics of randomized controlled trials of yoga [18]. Hung and Ernst assessed the methodological quality of randomized clinical trials of herbal medicine research between 1977 and 2007 [19]. Kim and colleagues analyzed randomized controlled trials on complementary and traditional medi-cine in the Korean literature using bibliometric analysis [20]. Moreover, Han and Ho evaluated the global trend of acupuncture research based on the Science Citation Index-Expanded database between 1991 and 2009 [21]. The evidence base of clinical studies of Tai Chi for health-care was evaluated bibliometrically using the PubMed database, the Cochrane Library, and four major Chi-nese electronic databases [11]. In addition, the statuses of complementary medicine research in China, Taiwan, and Hong Kong were compared bibliometrically based on publications from 2000 to 2009, identified from the PubMed database and the Journal Citation Reports [22]. Nevertheless, to our knowledge, no studies have specifi-cally explored the bibliometric profile of aromatherapy research. Therefore, the present study used bibliometric analysis to study the profile of research articles on aro-matherapy published in the past two decades (1995–2014) and to identify topical hotspots in aromatherapy research.

    MethodsThe Thomson Reuters Web of Science website was used to identify research articles on the topic of aromather-apy. The Science Citation Index-Expanded database was selected. The search was conducted on July 1, 2015. The publication period was limited to 20  years, 1995–2014. Original and review articles were selected for further analyses. The records extracted were analyzed for cita-tion characteristics, including the distribution of pub-lication years, languages, countries or regions, journals, articles, and authors using HistCite 12.03.17 (HistCite Software LLC) [23].

    The observed distribution of the frequency of authors and the number of their publications was fitted with the distribution function depicted by the Lotka’s law using a computer program to obtain the values of the exponent n (i.e., the slope of the log–log plot) and the constant c (the fraction of authors with only a single publica-tion) (LOTKA version 1.02). The deviation between the observed and the theoretical distribution function was evaluated using the Kolmogorov–Smirnov goodness-of-fit test [24]. In addition, the frequency of journals and the number of the articles that they contained were also evaluated with the computer program.

    In addition, VOSviewer v.1.61 for Microsoft Windows (Centre for Science and Technology Studies, Leiden Uni-versity, The Netherlands) [25] was used to construct bib-liometric diagrams for visualization of co-citation of the journals and co-occurrence of the text corpus extracted from the title and the abstract fields of the articles. Co-citation can be defined as any two items (authors) that have been jointly cited by another item (author). Thus, the more co-citations two items received, the more likely that they are related [26]. The fractional counting method was used when constructing the co-citation network. With fractional counting, if a citing article contains n ref-erences, each citation will count for only 1/n of the over-all citations.

    For the co-occurrence analysis, the text min-ing functionality of the VOSviewer first identifies the noun phrases in the text corpus based on the Apache OpenNLP toolkit, and then it converts all plural noun phrases into singular ones. The relevance of the resulting noun phrases was determined by comparing the pattern of their co-occurrences. While noun phrases with a low relevance will exhibit a random pattern of co-occurrence with other noun phrases, those with a high relevance will co-occur mainly with a limited set of other noun phrases [27]. In this study, the noun phrases (hereinafter referred to as “terms”) identified by VOSviewer were also manually inspected. Words of similar meaning or abbre-viation (for example, “cam” and “complementary”) were

  • Page 3 of 9Koo BMC Res Notes (2017) 10:46

    merged into its canonical form. Terms that deemed unin-formative such as “year”, “change” and publishers’ name were eliminated to improve the clarity of the resulting network.

    ResultsA total of 661 publications on aromatherapy, published between 1995 and 2014, were retrieved from the Web of Science. The distribution of article types is shown in Table 1. Of them, 465 (70.4%) were original articles and 84 (12.7%) were review articles. These 549 articles were included in the subsequent analyses.

    Figure 1 indicates that the number of articles increased steadily during the 20-year period with 67 articles pub-lished in 2014. As expected, the majority of the articles were written in English (95.8%) (Table 2). Authors from a total of 58 countries or regions contributed to the 549 published articles. The United States had the most pub-lished articles (19.5%), followed by the United Kingdom (17.3%). In terms of citations per paper, Australia was the leading country (34.5%) (Table 3).

    Of the 1888 authors, Edzard Ernst of the Exeter Univer-sity, United Kingdom had authored or co-authored the highest number of articles on the topic of aromatherapy (13 articles), followed by Myeong Soo Lee of the Korea Institute of Oriental Medicine, South Korea (12 articles) and Myung-Haeng Hur of the Eulji University, South Korea (10 articles). Moreover, 1654 authors (87.6%) pub-lished only one article, 167 authors (8.8%) published two articles, 43 authors (2.3%) published three articles, and only 24 authors (1.3%) published four or more articles on the topic of aromatherapy.

    The 549 articles were published in 287 different jour-nals. Table 4 shows the top 20 journals with the highest number of original and review articles on aromatherapy.

    Six of them were of the Web of Science category “Inte-grative and Complementary Medicine”. The median impact factor was 1.77 and six were quartile 1 journals, seven were quartile 2 journals, according to the classi-fication of the Journal Citation Reports. Regarding the number of articles published in each journal, Journal of Alternative and Complementary Medicine published the most articles (31 articles), followed by Complementary Therapies in Medicine (27 articles), and Evidence-based Complementary and Alternative Medicine (21 articles). In addition, 17 journals contained a range of five to nine articles, eight journals contained four articles, 14 jour-nals contained three articles, 48 journals contained two articles, and 197 journals contained only one article.

    Table 1 Distribution of  types of  articles on  aromatherapy published between 1995 and 2014 (N = 661)

    Only “Original article” and “review” were included in subsequent analyses

    Article type n %

    Original article 465 70.4

    Review 84 12.7

    Meeting abstract 40 6.1

    Proceedings paper 25 3.8

    Article; proceedings paper 15 2.3

    Editorial material 15 2.3

    Letter 10 1.5

    News item 3 0.5

    Correction 2 0.3

    Book review 1 0.2

    Note 1 0.2

    Fig. 1 Time trend of the number of original and review articles on aromatherapy published per year from 1995 to 2014

    Table 2 Languages used original and  review articles on  aromatherapy published between  1995 and  2014 (N = 549)

    TGCS total global citation score = total number of citations receivedCitations/article = TGCS/number of articles

    Language n % TGCS Citations/article

    English 526 95.8 8934 17.0

    Korean 7 1.3 22 3.2

    German 6 1.1 7 1.2

    Japanese 2 0.4 2 1.0

    Portuguese 2 0.4 5 2.5

    Turkish 2 0.4 3 1.5

    French 1 0.2 1 1.0

    Italian 1 0.2 0 0

    Polish 1 0.2 0 0

    Spanish 1 0.2 0 0

  • Page 4 of 9Koo BMC Res Notes (2017) 10:46

    Furthermore, the top 50 ranking journals (17.4% out of the 287 journals) accounted for 272 or 49.5% of the 549 articles.

    Table  5 shows the 10 most cited original and review articles on aromatherapy published between 1995 and 2014. The top-ranking paper, with 357 citations, was published in Complementary Therapies in Medicine. The second-ranking paper was a review article published in Phytotherapy Research in 2007 with 278 citations. Since the earlier the published year, the longer the duration that an article has an opportunity to be cited, a citation score per year was also calculated to provide a different index for comparison. In addition, these articles were found to rank at the same position based on the number obtained from the Google Scholar citations.

    Visualization analysis of the citation data were further explored using VOSviewer. Figure  2 shows the results of co-citation analysis of the 287 journals that received at least 50 co-citations. The size of a circle reflects the number of citations that a journal has received while the distance between two journals indicates the strength of the relatedness between them. Five clusters containing 55 journals were identified. Cluster 1 (red) consisted of 21 journals mainly publishing in complementary medicine and nursing research. Cluster 2 (green) consisted of 15 journals of medicinal chemistry and food science. Cluster 3 (blue) consisted of 11 journals of general medicine and geriatric medicine. Cluster 4 (purple) consisted of four

    journals focusing on entomology and Cluster 5 (yellow) consisted of four journals in dermatology.

    Figure  3 shows the co-occurrence network of terms that occurred in the title or abstract of at least 20 arti-cles. Overall, 84 of the 12,261 terms meet the criteria and the top 60% of the most relevant terms, that is, 50 terms are displayed in the figure. Cluster 1 (red) had 23 terms and the highest co-occurrence term was “essential oil” (216 co-occurrences). Cluster 2 (green) had 14 items with “intervention” receiving 121 co-occurrences followed by “massage therapy” receiving 109 co-occurrences. Cluster 3 (blue) had 13 items with “complementary medicine” and “alternative medicine” receiving 78 and 74 co-occur-rences, respectively.

    DiscussionIn this bibliometric study, we present the results of pub-lication on the topic of aromatherapy published between 1995 and 2014. The analyses of the growing trend of the number of original and review articles over the period, language used, and countries did not expose unexpected findings. Although over half of the 549 articles originated from authors from non-English speaking regions of the world, 95% of the articles were written in English. This finding reflects not only that English is the de facto global language of scientific communication [28] but also the characteristic of the Science Citation Index, which con-tains relatively few non-English language journals [29].

    Of the 1888 authors, the two most prolific authors in aromatherapy revealed by this study, Edzard Ernst and Myeong Soo Lee were also highly productive in other subfields of complementary medicine. The distribution of the number of articles published by the authors in this study was evaluated with the Lotka’s law of scientific pro-ductivity [30]. Based on the statistical distribution of the productivity of authors based on Chemical Abstracts, Lotka observed that “… the number (of authors) making n contributions is about 1/n2 of those making one; and the proportion all contributors, that make a single con-tribution, is about 60%.” In other words, the number of authors producing n articles is proportional to 1/n2 or similarly, the number of journals containing n articles is proportional to 1/n2. Our study found that only 12 authors contributed to five or more articles while 1654 of the 1888 authors (88%) contributed to only one article. However, the LOTKA computer program [24] failed to fit a Lotka’s power law distribution to our observed data.

    On the other hand, the distribution of the 549 aroma-therapy articles in the 287 journals fitted well, as indi-cated by the Kolmogorov–Smirnov goodness-of-fit test, according to the Lotka’s power law. A n of 2.424 and a c of 0.728 were obtained from the computer program LOTKA and therefore, the Lotka power function can be

    Table 3 Top 15 countries or regions with  origi-nal and  review articles on  aromatherapy published between 1995 and 2014 (N = 549)

    TGCS total global citation score = total number of citations receivedCitations/article = TGCS/number of articles

    Country or region No. of articles % TGCS Citations/article

    United States 107 19.5 2024 18.9

    United Kingdom 95 17.3 2790 29.4

    Japan 57 10.4 781 13.7

    Australia 37 6.7 1277 34.5

    Germany 29 5.3 409 14.1

    South Korea 29 5.3 162 5.6

    Brazil 27 4.9 272 10.1

    Unknown 24 4.4 257 10.7

    Taiwan 18 3.3 86 4.8

    Iran 17 3.1 45 2.7

    Turkey 17 3.1 34 2.0

    Austria 15 2.7 283 18.9

    People’s Republic of China

    15 2.7 146 9.7

    Canada 13 2.4 280 21.6

    Italy 12 2.2 170 14.2

  • Page 5 of 9Koo BMC Res Notes (2017) 10:46

    expressed as Y = 0.728/X2.424, where X is the number of articles and Y is the relative frequency of journals with X articles was obtained. According to this formula, 72.8% of the journals can be estimated to contain only one arti-cle. The value of n is larger than the 2 that originally sug-gested by Lotka but smaller than the 3.5 that recently reported in a study of citation data from the Scopus data-base [31]. Previous research indicated that the exponent n and the constant c could be influenced by the subject area and its productivity, the state of development, the country of origin, the time period of the study, and the length of that period [32].

    As anticipated by the power law, most articles were concentrated in several journals. In fact, almost a quar-ter of the articles were published in only three journals, namely, Journal of Alternative and Complementary Medicine, Complementary Therapies in Medicine, and Evidence-based Complementary and Alternative Medi-cine. Hence, these journals can be considered as the core

    journals for knowledge dissemination of aromatherapy research.

    The top 10 most cited original and review articles on aromatherapy published between 1995 and 2014 were analyzed to reveal the types of research in aromatherapy (Table  5). The top-ranking paper reported the findings from a postal survey of 2669 adults in England regarding their out-of-pocket expenditure on practitioner-provided complementary therapies and over-the-counter remedies [33]. The second-ranking paper was a review article pub-lished in 2007. The article described the possible mode of action of essential oils and their volatile constituents and outlined the therapeutic properties of essential oils in aroma and massage therapy [34]. Moreover, half of the 10 most cited articles were review articles. This finding is not surprising since systematic reviews and meta-analy-sis occupy the highest position in the current proposed hierarchy of evidence [35]. In addition, another possible reason for the high citation counts in review articles is

    Table 4 Top 20 journals with  the highest number of  original and  review articles on  aromatherapy published between 1995 and 2014 (N = 549)

    TGCS total global citation score = total number of citations receivedCitations/article = TGCS/number of articlesa Impact factors were obtained from the 2015 release of Journal Citation Reports Science Edition with 2014 data

    Rank Journal Web of Science subject category No. of cited articles

    % TGCS Citations/ article

    Impact factora (quartile)

    1 Journal of Alternative and Complemen-tary Medicine

    Integrative and complementary medicine 31 5.6 315 10.2 1.585 (2)

    2 Complementary Therapies in Medicine Integrative and complementary medicine 27 4.9 1029 38.1 1.545 (2)

    3 Evidence-based Complementary and Alternative Medicine

    Integrative and complementary medicine 21 3.8 92 4.4 1.880 (2)

    4 Phytotherapy Research Chemistry, medicinal 9 1.6 658 73.1 2.660 (2)

    5 Cochrane Database of Systematic Reviews

    Medicine, general and internal 8 1.5 118 14.8 6.032 (1)

    6 Natural Product Communications Food science and technology 8 1.5 80 10.0 0.906 (3)

    7 Contact Dermatitis Dermatology 7 1.3 246 35.2 3.747 (1)

    8 International Journal of Neuroscience Neurosciences 7 1.3 296 42.3 1.521 (4)

    9 Flavour and Fragrance Journal Food science and technology 6 1.1 44 7.3 1.970 (2)

    10 Journal of Applied Entomology Entomology 6 1.1 17 2.8 1.650 (2)

    11 Journal of Essential Oil Research Food science and technology 6 1.1 44 7.3 0.787 (3)

    12 Palliative Medicine Medicine, general and internal 6 1.1 252 42.0 2.855 (1)

    13 BMC Complementary and Alternative Medicine

    Integrative and complementary medicine 5 0.9 25 5.0 2.020 (2)

    14 Forschende Komplementarmedizin Integrative and complementary medicine 5 0.9 22 4.4 1.079 (3)

    15 Iranian Red Crescent Medical Journal Medicine, general and internal 5 0.9 2 0.4 0.634 (4)

    16 Journal of Ethnopharmacology Integrative and complementary medicine 5 0.9 67 13.4 2.998 (1)

    17 Journal of Korean Academy of Nursing Nursing 5 0.9 20 4.0 0.380 (4)

    18 Journal of PeriAnesthesia Nursing Nursing 5 0.9 12 2.4 0.943 (3)

    19 Phytomedicine Chemistry, medicinal 5 0.9 163 32.6 3.126 (1)

    20 Supportive Care in Cancer Rehabilitation 5 0.9 72 14.4 2.364 (1)

    Median 76 10.1 1.765

  • Page 6 of 9Koo BMC Res Notes (2017) 10:46

    because they are often cited under the introduction sec-tion of original articles. A study of the 100 most-cited papers in each of 21 scientific fields during the period 1996–2006 found that a considerable number of the arti-cles in each field were review articles [36].

    Visualization analysis was used to create a two-dimensional map of co-citation network of journals that received at least 50 co-citations (Fig. 2). Five clusters con-taining 55 journals were generated by the VOSviewer. The cluster 1 (red) formed by the 21 journals focusing on complementary medicine were distanced similarly from two other clusters: cluster 2 (green) formed by 15 jour-nals in medicinal chemistry and food science and cluster 3 (blue) formed by 11 journals in general medicine and geriatric medicine. This distribution pattern indicated

    that while there was high relatedness among the articles within each cluster, moderate relatedness also existed between cluster 1 and 2 and between cluster 1 and 3. On the other hand, cluster 4 (purple) and especially cluster 5 (yellow) had much lower relatedness with the articles in the complementary medicine cluster.

    To locate popular research topics on aromatherapy research published between 1995 and 2014, the co-occurrence of terms in the title or abstract of at least 20 articles was analyzed. Three clusters with a total of 50 terms were identified. Cluster 1 (red) consisted of terms related to essential oil such as the mode of administra-tion (inhalation), type of oil (lavender), study design (experiment, placebo), and outcome (stress, blood pres-sure). The second cluster (green) composed of terms

    Table 5 Ten most-cited original and review articles on aromatherapy published between 1995 and 2014 (N = 549)

    Global citation score = citation frequency based on the full Web of Science count at the time the data was downloadedGlobal citation score per year = global citation score/(2015 – the year of publication)The number of Google Scholar citations was obtained from https://scholar.google.com/scholara Impact factors were obtained from the 2015 release of Journal Citation Reports Science Editon with 2014 data

    Rank First author(no. of total authors)

    Title Journal(impact factora)

    Year of  publication

    Global citation score

    Global citation score per year

    No. of Google Scholar citations

    1 Thomas KJ(3)

    Use and expenditure on comple-mentary medicine in England: a population based survey

    Complementary Thera-pies in Medicine (1.545)

    2001 357 25.5 677

    2 Edris AE(1)

    Pharmaceutical and therapeutic potentials of essential oils and their individual volatile constituents: a review

    Phytotherapy Research (2.660)

    2007 278 34.8 493

    3 Kronenberg F(2)

    Complementary and alternative med-icine for menopausal symptoms: a review of randomized, controlled trials

    Annals of Internal Medicine (17.810)

    2002 270 20.8 556

    4 MacLennan AH(3)

    The escalating cost and prevalence of alternative medicine

    Preventive Medicine (3.086)

    2002 224 17.2 467

    5 Lorenz KA(14)

    Evidence for improving palliative care at the end of life: a systematic review

    Annals of Internal Medicine (17.810)

    2008 214 30.6 418

    6 Ernst E(2)

    The BBC survey of complementary medicine use in the UK

    Complementary Thera-pies in Medicine (1.545)

    2000 210 14.0 460

    7 Cavanagh HMA (2)

    Biological activities of lavender essential oil

    Phytotherapy Research (2.660)

    2002 156 12.0 335

    8 DeGroot AC(2)

    Adverse reactions to fragrances—a clinical review

    Contact Dermatitis (3.747)

    1997 149 8.3 14

    9 Ballard CG(4)

    Aromatherapy as a safe and effective treatment for the management of agitation in severe dementia: the results of a double-blind, placebo-controlled trial with Melissa

    Journal of Clinical Psychiatry (5.498)

    2002 113 8.7 411

    10 Ballard CG(7)

    Management of agitation and aggression associated with Alzhei-mer disease

    Nature Reviews Neurol-ogy (15.358)

    2009 108 18.0 181

    https://scholar.google.com/scholar

  • Page 7 of 9Koo BMC Res Notes (2017) 10:46

    that dealt with interventions (aromatherapy, massage therapy) and medical conditions such as nausea, demen-tia, and cancer. Systematic reviews and reviews came out as prominent terms because 16% of the articles were reviews. In addition, the appearance of the term “child” reflected a few well-cited survey studies and reviews on complementary medicine use in children [37–40]. Finally, Cluster 3 (blue) contained general terms of complementary medicine, methods of knowledge acquisition (survey, questionnaire), and related comple-mentary therapies (homeopathy, reflexology). The latter co-occurrence could be explained by the fact that these therapies were often included in survey studies [41–43] and disease-specific reviews [44, 45] of complementary medicine along with aromatherapy. The visualization of

    co-occurrence network could be used not only to show the pattern and hot spots of aromatherapy therapy in the past, but may also help to reveal potential or neglected research areas.

    Several intrinsic limitations of this bibliometric analy-sis should be noted. First, it is possible that some articles could be missed with the use of a single citation data-base. Further studies can evaluate other databases such as Scopus and Google Scholars and to compare their findings with those from this study. Second, the Sci-ence Citation Index database is biased towards English-language journals and therefore, the results should be interpreted as such. Moreover, the non-English language journals included in the Science Citation Index data-base was found to have a lower impact than those in the

    Fig. 2 Co-citation network of journals with original and review articles on aromatherapy published between 1995 and 2014 that received at least 50 co-citations. Five clusters were identified: cluster 1 (blue, top left), cluster 2 (red, middle left), cluster 3 (green, bottom middle), cluster 4 (purple, right), and cluster 5 (yellow, inset). The inset (bottom left corner) shows the full co-citation network map with two journals (Journal of Chemical Ecology and Florida Entomologist). Clusters located close to each other in the figure indicate related topics

  • Page 8 of 9Koo BMC Res Notes (2017) 10:46

    English-language journals [29]. Therefore, the compari-sons of publication output among countries might be affected.

    ConclusionsThis study was the first bibliometric analysis of aroma-therapy research. Prolific authors, core journals, and clusters of aromatherapy research in the past two dec-ades were identified. This study provided a systematic overview of productivity and visibility of research work in aromatherapy and the findings could be used for organizing and prioritizing future research efforts in aro-matherapy research.

    Authors’ contributionsNot applicable.

    Author details1 Department of Medical Research, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 2 Minsheng Road, Dalin, Chiayi 62247, Taiwan. 2 Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.

    AcknowledgementsNone.

    Competing interestsThe author declares that he has no competing interests.

    Availability of data and materialsData were used under license from Thomson Reuters. Readers can contact Thomson Reuters at the following URL: http://ipscience.thomsonreuters.com/product/web-of-science/.

    Received: 31 March 2016 Accepted: 30 December 2016

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    A bibliometric analysis of two decades of aromatherapy researchAbstract Background: Methods: Results: Conclusions:

    BackgroundMethodsResultsDiscussionConclusionsAuthors’ contributionsReferences