PAREXEL® CLINICAL RESEARCH SERVICES: CLINICAL TRIAL SUPPLIES & LOGISTICS

NORTH AMERICAN COORDINATION HUB AND DISTRIBUTION CENTEREnd-to-End Clinical Supply Chain Management

A WORLD CLASS COORDINATION HUB AND

DISTRIBUTION CENTER

PAREXEL’s new state-of-the art coordination hub and distribution center will help you more efficiently manage clinical trial supplies across North America, and globally.

PAREXEL takes an integrated approach to ensure clinical trial supplies, ancillary supplies, and central lab services are delivered on time and on budget.

Whether you are conducting a small regional study or undertaking a complex global trial, your presence in North America requires a robust supply chain network that includes country-specific knowledge and a close connection to local authorities. PAREXEL provides that presence and expertise.

1

PAREXEL’S NORTH AMERICAN COORDINATION HUB AND DISTRIBUTION CENTER OFFERS CLINICAL TRIAL SUPPLIES AND LOGISTICS SERVICES DESIGNED TO REDUCE STUDY START-UP AND ACCELERATE FIRST-PATIENT-IN.

STRATEGIC SOURCING, MANUFACTURING AND PACKAGING

2

Every clinical trial is unique. As a result, there is no “one-size fits all” approach to the sourcing, manufacturing and distribution of clinical trial supplies. From Quakertown, PA, PAREXEL’s Clinical Trial Supplies & Logistics group will customize a sourcing, manufacturing and distribution strategy that is efficient, robust and compliant with all local regulations across the globe.

The Coordination Hub and Distribution Center can:

• Provide local and/or central sourcing of comparator and non-investigational medicinal products

• Coordinate investigational medicinal products manufacturing through our contract manufacturing organization partners or sponsor-delegated partners to optimize material utilization, supply and re-supply strategies, expiration dates and costs

• Offer full-service and secondary clinical packaging for randomized, double-blind or two/three panel studies, as well as customized packaging design, custom secondary packaging and patient supply kits

• Develop, translate and distribute all the documen- tation for sites, investigators or patients

GLOBAL TRADE COMPLIANCE, IMPORT/EXPORT & REGULATORY SUPPORT:

3

ANCILLARY SUPPLIES

• Material sourcing

• Storage and distribution

• Fulfillment and distribution

• Return and recycling

CLINICAL TRIAL SUPPLIES

• Secondary packaging and labeling

• Storage and distribution of - (-)20* storage - 2-8* storage - 15- 25* storage - (-) 70* storage

(on request)

• Controlled substances, packaging and labeling

• Drug comparator sourcing

• Return and destructionLABORATORY LOGISTICS SERVICES

• Lab kit production

GLOBAL DISTRIBUTION SOLUTIONS

PAREXEL’s North American Coordination Hub and Distribution Center is part of our global depot network of clinical logistics facilities that can store and distribute investigational medicinal products, clinical trials supplies, ancillary supplies and equipment and offer sophisticated capabilities including enhanced expiry date management, packaging and labeling services, returns and destruction.

The North American Coordination Hub and Distribution Center’s flexible regional distribution services can serve small regional studies and complex global trials, and can be scaled for entire development programs. Distribution is executed according to PAREXEL’s standard operating procedures, which are designed to accelerate project setup, decrease turnaround times and minimize supply chain issues.

4

THE NORTH AMERICAN COORDINATION HUB AND DISTRIBUTION CENTER EXPANDS PAREXEL’S GLOBAL CLINICAL TRIAL SUPPLIES AND LOGISTICS INFRASTRUCTURE IN THE AMERICAS, EUROPE, AFRICA AND THE ASIA PACIFIC REGION.

New York

Philadelphia

“STUDY IN A BOX” SIMPLIFIES LOGISTICS, IMPROVES INVENTORY CONTROL

PAREXEL’s North American Coordination Hub and Distribution Center can consolidate all clinical trials supplies, as well as ancillary and lab supplies into a “study in a box”. Designed to reduce the risk of misplaced materials, increase inventory trans- parency, study in a box can significantly reduce shipping costs.

A SINGLE POINT OF CONTACT FOR ALL YOUR CLINICAL LOGISTICS NEEDS

PAREXEL’s Coordination Hub and Distribution Center is managed and staffed by PAREXEL personnel who are trained to high standards and have full understanding of regulatory compliance.

Working with PAREXEL ensures that logistical planning and execution is integrated into the entire clinical trial process beginning with study start-up planning through the end of each study’s lifecycle.

WAREHOUSING INFRASTRUCTURE AND IT SYSTEMS TO TRACK AND TRACE SHIPMENTS AND MANAGE INVENTORY LEVELS

PAREXEL’s Clinical Trials Supplies systems enable us to have the right products in the right place at the right time. Our intelligent software provides full clinical supply chain transparency, and enables us to optimize inventory control across our depot network.

5

To learn how PAREXEL’s North American Coordination Hub and Distribution Center can optimize your reach globally, visit: www.PAREXEL.com/logistics or contact:

Tony Street Senior Director, Global Business Development Clinical Trial Supplies & Logistics +44 (0) 1895 818 960 tony.street@PAREXEL.com

PAREXEL’S NORTH AMERICAN COORDINATION HUB AND DISTRIBUTION CENTER— LOCATION

PAREXEL designed the facility in Quakertown, PA from the ground-up to serve as a clinical trial supplies and logistics center for all of North America. The 5,500 m2 coordination hub and distribution center is close to the eastern seaboard’s major airports and major highway routes to ensure your clinical supplies arrive at your trial location in no more than one day.

This prime location makes distribution throughout the Americas easy and reduces the risk of costly clinical supply chain delays.

Address: PAREXEL International 2710 Milford Square Pike Quakertown, PA, USA 18951

WHEREVER YOUR JOURNEY TAKES YOU, WE’RE CLOSE BY.

CORPORATE HEADQUARTERS

195 West Street Waltham, MA 02451 USA +1 781 487 9900

Offices across Europe, Asia and the Americas

www.PAREXEL.com

©2016 PAREXEL International Corporation. All rights reserved.