patients with t2d presenting with glycosuria: examining the sglt2 moa

31
Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Upload: jessamine-hobbs

Post on 31-Dec-2015

39 views

Category:

Documents


2 download

DESCRIPTION

Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA. Goals. Diagnosed Diabetes, 1958-2010. Despite Increasing Prevalence, T2D Remains Undertreated. Limitations of Conventional Glucose-Lowering Agents. Limitations of Conventional Glucose-Lowering Agents (cont). - PowerPoint PPT Presentation

TRANSCRIPT

Page 1: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Patients With T2D Presenting With Glycosuria: Examining the

SGLT2 MOA

Page 2: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA
Page 3: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Goals

Page 4: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Diagnosed Diabetes, 1958-2010

Page 5: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Despite Increasing Prevalence, T2D Remains Undertreated

Page 6: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Limitations of Conventional Glucose-Lowering Agents

Page 7: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Limitations of Conventional Glucose-Lowering Agents (cont)

Page 8: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

The Need for Novel Antihyperglycemic Agents

Page 9: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Pathophysiologic Pathways Affecting Glycemic Control in

T2D

Page 10: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

SGLT2 and Glucose Control

Page 11: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

SGLT2: Novel Target for Glucose Control

Page 12: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Currently FDA-approved SGLT2 Inhibitors

Page 13: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Glycosuria: Concerns in Urgent Care Settings

Page 14: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Clinical Trial Findings for SGLT2 Inhibitors

Page 15: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Clinical Trial Findings for SGLT2 Inhibitors: Extraglycemic Effects

Page 16: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA
Page 17: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA
Page 18: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

SGLT2 Inhibitors: Risk of Hypotension

Page 19: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA
Page 20: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Treating Patients With Type 2 Diabetes and CKD

Page 21: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA
Page 22: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA
Page 23: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Abbreviations

Page 24: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

Abbreviations (cont)

Page 25: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References

Page 26: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References (cont)

Page 27: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References (cont)

Page 28: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References (cont)

Page 29: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References (cont)

Page 30: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References (cont)

Page 31: Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

References (cont)