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Università degli Studi di Perugia

Ordine Provinciale dei Medici Chirurghi

e degli Odontoiatri di Perugia

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Società Italiana di Farmacologia

Società Italiana di Neurofisiologia Clinica

International Headache Society

PRESENTATION

The National Congress stands as a crucial moment, among the scientific and educational activities of the Italian Society for the Study of Headache (SISC), intergrating the most important aspects in headache research and clinical and therapeutic advancements. Its objective is to provide the most appropriate recommendations for the management of adult, child or adolescent patients, in different care settings, in accordance with the multidisciplinary nature of SISC. Particular attention will be placed on the psychobiological bases underlying this heterogeneous group of disorders and on the therapeutic strategies best suited for their treatment. Specific sessions will cover physiological conditions and comorbidities (psychopathological disorders, in particular, depression, sleep, and vascular disorders) that modulate the expression of the disease in the patient. Other topics of interest will include the relationship between headaches and neuropathic pain (including clinical, pathophysiological and therapeutic aspects) and the chronic forms, especially those with symptomatic drug overuse, which present management difficulties in clinical practice and require the development of targeted and validated protocols. Pharmacological and non-pharmacological approaches will be addressed with specific reference to the related pathophysiology interventions at different levels: control of the neurovascular and cardiovascular responses, modulation of the transmission/perception of pain, role of inflammation and immunity mechanisms, and hormonal regulation. Among the most recent therapeutic aspects botulinum toxin, new neurostimulation techniques, antiepileptic drugs and antidepressants, anxiolytics and hypnotic drug, hormone therapy, and specific symptomatic and anti-inflammatory drugs will be discussed. The conference is open to: neurologists, neurophysiologists, pharmacologists, internists, psychiatrists, child psychiatrists and paediatricians, anesthetists, general practitioners and psychologists, and all professionals working within the National Health System operating in the field of headaches. The National SISC Congress of Perugia 2013 would like to be an innovative learning project that enhances the content and the interaction between specialists of different disciplines, in an environment that is characterized, also structurally, as an example of effective exchange between the University and the National Health System.

Giorgio Bono

President Italian Society for the Study of Headache

Paolo Calabresi

President XXVII National SISC Congress

XXVII NATIONAL CONGRESS

Presidents Giorgio Bono, Paolo Calabresi

Scientific Committee

Anna Ambrosini, Maria Gabriella Buzzi, Rosanna Cerbo, Gianluca Coppola Letizia Maria Cupini, Marina de Tommaso, Cherubino Di Lorenzo

Vittorio Di Piero, Anna Ferrari, Ferdinando Maggioni Rossella Nappi, Maria Pia Prudenzano, Paolo Rossi Grazia Sances, Giorgio Sandrini, Paola Sarchielli

Lidia Savi, Elisabetta Tozzi, Andrea Truini, Massimiliano Valeriani

Organising Committee Stefano Caproni, Ilenia Corbelli, Cinzia Costa

Giovanni Mazzotta, Sabrina Siliquini

Scientific Secreteriat Paola Sarchielli

___________________________________________

ITALIAN SOCIETY FOR THE STUDY OF HEADCHES

Executive Committee

President Giorgio Bono

President Elect

Paolo Martelletti

Past President Luigi Alberto Pini

General Secretary Treasurer Fabio Antonaci Anna Ambrosini

Councillors

Filippo Brighina, Cinzia Costa, Pierangelo Geppetti Rosario Iannacchero, Federico Mainardi, Innocenzo Rainero

Honorary Presidents

Marcello Fanciullacci, Mario Giacovazzo, Vincenzo Guidetti Giuseppe Nappi, Lorenzo Pinessi, Emilio Sternieri, Giorgio Zanchin

Arbitrators

Enrico Del Bene, Anna Ferrari, Franco Mongini Davide Moscato, Rita Lucia Trinchi

Auditors

Giovanni Rossini, Elisabetta Tozzi, Leonardo Triggiani

___________________________________________

Interdisciplinary School of Advanced Education in Headache Director: Francesco Pierelli

The Journal of Headache and Pain Giornale delle Cefalee (founded by SISC in 1999) Editor: Carlo Lisotto Editor-in-Chief: Paolo Martelletti

International Headache Society European Headache Federation SISC Representative: Lidia Savi SISC Representative: Luigi Alberto Pini

Topics

• Headache, chronic pain and drug abuse • Emergency headache • New genetic and pathophysiological aspects in headaches • Neuroimaging in headache and other pain syndromes • Headache and cerebrovascular disease • Headache in childhood • Neuropathic pain and headache: differential and common mechanisms • Anxiety, depression and sleep disorders in patients with headache • Headache and autoimmune diseases • Rational management of symptomatic drugs and new therapeutic perspectives • Prophylactic treatment and rational use of botulinum toxin • AEDs in headaches and chronic pain • Neurostimulation techniques in headaches • Medical-legal aspects in the management of headaches

Teaching courses:

• “Headache in clinical practice” for General Practitioners

• “Headache in children: from theory to clinical” for Paediatricians, Child and Adolescent Neuropsychiatrists and Psychologists

Joint sessions with:

Italian Society of Clinical Neurophysiology (SINC)

Neuroscience and Pain Group of the Italian Society of Neurology

Symposia:

• Headache and triptans: news and controversies • Botulinum toxin type A: a new treatment option for chronic migraine

Invited Lectures

Other events

• Round table with lay associations

Thrusday, 26 September 2013 Historial Centre – Palazzo dei Priori - Sala dei Notari 13.00-14.00 SISC Regional Sections Meeting Chair: G. Bono (Varese) 14.00-14.20 Lecture Presentation: L. Savi (Turin) The new International Classification of Headache Disorders: ICHD-3 beta C. Tassorelli (Pavia) 14.20-15.00 Scientific Session: Migraine and women Chairs: M.G. Buzzi (Rome), P. Sarchielli (Perugia) 14.20-14.40 Migraine in the various stages of a woman's life I. Corbelli (Perugia) 14.40-15.00 Is the progestin-only contraception in migraine women more secure? R.E. Nappi (Pavia) 15.00 -15.30 Magistral Lecture "Federigo Sicuteri" Presentation: P. Calabresi (Perugia) Migraine: a disorder of the excitatory-inhibitory brain balance D. Pietrobon (Padua) 15.30-17.30 Scientific Session: Comorbidities in headaches Chairs: A. Carolei (L’Aquila), V. Di Piero (Rome) 15.30-15.50 Anxiety, depression and migraine: a two-way relationship

R. Torta (Turin) 15.50-16.10 Sleep disturbance and primary headaches

L. Ferini Strambi (Milan) 16.10-16.30 Epilepsy and headache: a controversial report

E. Beghi (Milan) 16.30-16.50 Headache and dysimmune systemic diseases

R. Gerli (Perugia) 16.50-17.10 The connection between migraine and ischemic stroke: potential pathogenic mechanisms and recommendations

S. Sacco (L’Aquila) 17.10-17.30 Headache and fibromyalgia M.A. Giamberardino (Chieti) 17.30-18.00 Lecture Presentation: M. Fanciullacci (Florence)

Headache pharmacogenomics M. Del Zompo (Cagliari) 18.00 Opening ceremony G. Bono (Varese), P. Calabresi (Perugia) 18.15-18.45 Magistral Lecture "Alessandro Agnoli" Presentation: P. Calabresi (Perugia) Modulation of pain: old and new drug targets F. Nicoletti (Rome) 20.00 Welcome Cocktail Hotel Brufani Palace

Friday, 27 September 2013 University Hospital, School of Medicine PLENARY HALL 8.30-10.00 Scientific Session: Pathogenetic aspects of headaches

Chairs: P. Calabresi (Perugia), P. Martelletti (Rome)

8.30-8.50 TRP channels in headache and pain P. Geppetti (Florence) 8.50-9.10 Genes and primary headaches I. Rainero (Turin) 9.10-9.30 Cortical spreading depression as a target of antimigraine drugs C. Costa (Perugia) 9.30-9.50 OMICS in migraine L.A. Pini (Modena) 9.50-10.00 Discussion 10.00-10.30 Lecture Presentation: L. Pinessi (Turin) Is migraine a disease? P. Cortelli (Bologna) 10.30-11.00 Coffee Break POSTER EXHIBITION AREA Poster viewing 11.00-12.00 Symposium: Botulinum toxin Type A Allergan: a new treatment option for chronic

migraine patients In collaboration with Allergan S.p.A. Chair: P. Martelletti (Rome) 11.00-11.15 Neuroinflammatory pain in chronic migraine C. Tassorelli (Pavia) 11.15-11.30 Hypothesis of the sensory-motor mechanism of action for a unique and different molecule L.A. Pini (Modena) 11.30-11.45 Chronic pain in migraine as a target of the paradigm PREEMPT  P. Sarchielli (Perugia) 11.45-12.00 The course of the chronic migraine patient G. Zanchin (Padua) 12.00-12.30 Lecture Presentation: G. Nappi (Pavia) Functional neuroimaging in headaches G. Tedeschi (Naples)

PLENARY HALL 12.30-13.30 Symposium: Headache and triptans: news and controversies In collaboration with Istituto Lusofarmaco d’Italia S.p.A. Chairs: G. Zanchin (Padua), G. Bono (Varese) 12.30-12.50 Migraine with aura: in which stage should triptans be used? F. Mainardi (Venice) 12.50-13.10 The recurrence of the attack: how important is it for the patient? M.P. Prudenzano (Bari) 13.10-13.30 Weekend migraine: myth or reality? C. Lisotto (Pordenone) 13.30-14.30 Lunch POSTER EXHIBITION AREA 13.30-14.30 Poster viewing PLENARY HALL

14.30-16.00 Scientific Session: Neuroscience and Pain Study Group 14.30-15.00 Lecture Presentation: G. Sandrini (Pavia) Pharmacological treatment of neuropathic pain. Current knowledge and the future novelities G. Cruccu (Rome) 15.00-16.00 Controversy Chairs: M. de Tommaso (Bari), A. Truini (Rome) 15.00-15.30 Diagnosis of neuropathic pain. Self-sufficiency of the clinical approach M.R. Lacerenza (Milan) 15.30-16.00 Neuropathic pain diagnosis: we do need clinical neurophysiology M. Valeriani (Rome)

HALL 5 14.30-16.00 Scientific Session: From birth to adulthood Chairs: P.A. Battistella (Padua), V. Guidetti (Rome) 14.30-14.45 Headaches at early onset M. Valeriani (Rome) 14.45-15.00 Headache and cephalic autonomous system V. Raieli (Palermo) 15.00-15.15 Temperament and attachment in childhood headaches F. Galli (Pavia) 15.15-15.30 Headache and the school: what relations are there with learning disabilities? E. Tozzi (L’Aquila) 15.30-15.45 Medication overuse headache in childhood: case study of a specialized headache center P.A. Battistella (Padua) 15.45-16.00 Headache and personality structure in latency and in adolescence: perfectionism E. Salvi (Rome) PLENARY HALL 16.00-16.30 Lecture Presentation: G. Zanchin (Padua) Legal and medico-legal issues in drug prescription in headaches A. Castelnuovo (Turin) PLENARY HALL 16.30-18.00 Oral communications: Clinical aspects of headache I Chairs: L. D’Alonzo (Rome), A. Rossi (Perugia) HALL 1 16.30-18.00 Oral communications: Pathogenetic aspects of headache Chairs: G. Coppola (Latina), E. Pucci (Pavia) HALL 2 16.30-18.00 Oral communications: Case reports Chairs: C.A. Caputi (Ancona), F. Di Sabato (Rome) HALL 3 16.30-18.00 Oral communications: Headache in childhood and adolecence I Chairs: E. Del Bene (Florence), A. Verrotti Di Pianella (Perugia) HALL 4 16.30-18.00 Oral communications: Chronic headaches I Chairs: A. Panconesi (Empoli), E. Sternieri (Modena) HALL 5 16.30-18.00 Oral communications: Therapeutic aspects of headache Chairs: R. Iannacchero(Catanzaro), A. Negro (Rome) HALL 6 16.30-18.00 Oral communications: Neuroscience and pain Study Group I Chairs: A. Perrotta (Pozzilli), M. Valeriani (Rome)

PLENARY HALL 18.00-18.30 Lecture Presentation: F. Pierelli (Latina) Non-invasive neuromodulation in primary headaches J. Schoenen (Liège, Belgium)

18.30-19.45 SISC-SINC Joint session: Up-date on the pathophysiology of migraine: the contribution of neurophysiology

Chairs: A. Ambrosini (Pozzilli), F. Brighina (Palermo) 18.30-18.40 Connectivity in aura migraine: a study of EEG and fMRI V. Sciruicchio (Bari) 18.40-18.50 Role of lateral inhibition in determining the habituation deficit of migraine G. Coppola (Latina) 18.50-19.00 Pathophysiology of migraine between cortical excitability and homeostatic plasticity:

new neurophysiological evidence on the migraine cycle F. Brighina (Palermo) 19.00.19.10 Diagnostic validity of visual and auditory evoked potentials in migraine: a retrospective

study A. Ambrosini (Pozzilli) 19.10-19.20 The directionality of migraine pain behind different phenotypes? S. Pro (Rome) 19.20-19.30 Brain activity related to temporal processing of pain in chronic and episodic migraine' A. Perrotta (Pozzilli) 19.30-19.45 General discussion HALL 5 18.30-19.30 Round Table: Meeting with the lay associations Al.Ce Centro Group CIRNA Foundation Lega Italiana Cefalalgici (LIC) Organization for Understanding Cluster Headaches (OUCH) – Italia Onlus 20.30 SOCIAL EVENT

Scuola di Lingue Estere dell’Esercito – Complesso Santa Giuliana

Saturday, 28 September 2013 University Hospital, School of Medicine HALL 4 8.00-9.00 SISC General Meeting PLENARY HALL 9.00-9.30 Magistral Lecture "Giovanni Lanzi" Presentation: V. Guidetti (Rome) Headache and psychiatric comorbidity in children and adolescents U. Balottin (Pavia) 9.30-10.00 Lecture “Franco Michele Puca”

Presentation: E. Sternieri (Modena) Anandamide and menstrual migraine: a pilot study S. Benemei (Florence)

10.00-11.00 Focus on: Neurostimulation in refractory chronic migraine

Chairs: F. Antonaci (Pavia), R. Arcioni (Rome)

10.00-10.25 Selection criteria P. Martelletti (Rome)

10.25-10.50 Methods of intervention S. Palmisani (London)

10.50-11.00 Discussion 11.00-12.15 Scientific Session: Therapeutic aspects of headaches

Chairs: F. Granella (Parma), L.A. Pini (Modena)

11.00-11.15 Responsiveness to triptans in migraine patients M. Viana (Pavia) 11.15-11.30 High doses of corticosteroids and verapamil in episodic cluster headache G. Zanchin (Padua) 11.30-11.45 Do national guidelines have an impact on the treatment of migraine without aura attack?

Response from the patients M. Margoni (Padua) 11.45-12.00 Problems and solutions in the management of chronic headaches A. Ferrari (Modena) 12.00-12.15 Sodium valproate in the treatment of medication overuse headache: results of the Samoha Study S. Caproni (Perugia)

PLENARY HALL 12.15-13.15 Oral communications: Clinical aspects of headache II Chairs: A. Palmieri (S. Dona di Piave), P. Rossi (Grottaferrata)

HALL 1 12.15-13.15 Oral communications: Headache in childhood and adolecence II Chairs: M. Carotenuto (Naples), V. Sciruicchio (Bari) HALL 2 12.15-13.15 Oral communications: Chronic headache II Chairs: G. Dalla Volta (Brescia), L. Savi (Turin) HALL 3 12.15-13.15 Oral communications: Latest breaking news in basic science of migraine Chairs: P. Martelletti (Rome), P. Sarchielli (Perugia) HALL 4 12.15-13.15 Oral communications: Neuroscience and pain Study Group II Chairs: M. de Tommaso (Bari), F. Pierelli (Latina) PLENARY HALL 13.15-13.30 G. Nappi Cluster Headache Award Presentation: F. Antonaci (Pavia)

Lateralized central facilitation of trigeminal nociception in cluster headache D. Holle, C. Gaul, S. Zillessen, S. Naegel, S. Krebs, H.C. Diener, H. Kaube, Z. Katsarava, M. Obermann

13.30-14.00 Poster Awards and announcement of the winner of the Franco Michele Puca Award 2013 R. Cerbo (Rome), P. Geppetti (Florence), L.A. Pini (Modena) 14.00 Closing ceremony Farewell lunch

ORAL COMMUNICATIONS Friday, 27 September 2013 University Hospital, School of Medicine PLENARY HALL 16.30-18.00 Oral communications: Clinical aspects of headache I Chairs: L. D’Alonzo (Rome), A. Rossi (Perugia)

16.30-16.40 Chronic cerebro-spinal venous insufficiency (CCSVI) and migraine: does a link exist? B. Petolicchio, F. Passarelli, L. Di Biase, D. Tatulli, A. Viganò, V. Di Piero (Rome) 16.40-16.50 Migraine and hemorrhagic stroke: a meta-analysis R. Ornello, P. Ripa, F. Pistoia, A. Carolei, S. Sacco (L’Aquila) 16.50-17.00 Headache and cerebral ischemia due to intracranial atherosclerotic disease M. Bruno, F. Maggioni, F. Viaro, C. Baracchini, G. Zanchin (Padua) 17.00-17.10 Weather changes and headaches: an Emergency Department retrospective study C. Vollono, V. Gnoni, E. Mazzucchi, E. Testani, A. Losurdo, G. Della Marca (Rome) 17.10-17.20 Primary Headache and shift work: preliminary results on the study of the association in a

group of workers exposed to chemical risk E. Pucci, S. Bruscella, G. Taino, M. Imbriani, G. Sandrini (Pavia) 17.20-17.30 Headache characteristics and predisposing factors in an estensive population. A cross-

sectional study on 9501 subjects F. Mongini, C. Milani, A. Ugolini, L. Ferrero, E. Banzatti, A. Evangelista (Turin) 17.30-17.40 Diagnostic and therapeutic errors in cluster headache: a population-based study F. Antonaci, M. Allena (Pavia), C. Voiticovschi-Iosob (Pavia/Moldova), I. De Cillis, G. Nappi (Pavia) 17.40-17.50 Migraine management in a population with chronic pain: a description of 33 cases of

hypermobility type Ehlers-Danlos Syndrome F. Puledda, M. Toscano, B. Petolicchio, A. Viganò, C. Celletti, F. Camerota, V. Di Piero

(Rome) 17.50-18.00 Migraine and endocrine disorders: does a possible correlation exist? C. Lisotto (Pordenone), F. Mainardi (Venice), F. Maggioni, G. Zanchin (Padua)

HALL 1 16.30-18.00 Oral communications: Pathogenetic aspects of headache Chairs: G. Coppola (Latina), M.P. Prudenzano (Bari) 16.30-16.40 Dynamic changes in thalamic microstructure in migraine without aura patients: a diffusion tensor magnetic resonance imaging study G. Coppola (Latina/Rome), E. Tinelli, C. Lepre, E. Iacovelli, C. Di Lorenzo (Latina), G. Di Lorenzo (Rome), F. Pauri, G. Fiermonte, F. Bianco, F. Pierelli (Latina) 16.40-16.50 Cortical excitability changes n chronic migraine vs episodic migraine: evidence by

sound-induced flash illusions S. Indovino, S. Maccora (Palermo), N. Bolognini, G. Vallar (Milan), R. Baschi, S. Talamanca, G. Cosentino, F. Brighina, B. Fierro (Palermo) 16.50-17.00 Central mechanisms of migraine improvement with ketogenic diet: a visual evoked

potentials study C. Di Lorenzo, G. Coppola, M. Bracaglia, D. Di Lenola, F. Pierelli (Rome) 17.00-17.10 Lateral inhibition in somatosensory cortex of migraine without aura patients between

attacks M. Bracaglia (Latina), G. Coppola (Latina/Rome), E. Iacovelli, G. Fragiotta, V. La Salvia, D. Di Lenola, C. Di Lorenzo, F. Pierelli (Latina) 17.10-17.20 Identification of new genetic variants of KCNK18 in migraine with aura and migraine

without aura I. Rainero, E. Rubino, P. Fenoglio, S. Gallone (Turin), P. Zavarise, D. Carli (Brescia), S. Boschi, A. Gai, L. Pinessi (Turin), G. Dalla Volta (Brescia) 17.20-17.30 Effects of CGRP receptor antagonism in nitroglycerin–induced hyperalgesia C. Tassorelli, R. Greco, A.S. Mangione, F. Siani, F. Blandini, M. Avenali (Pavia), M.G. Buzzi (Rome), G. Sandrini, G. Nappi (Pavia) 17.30-17.40 Parthenolide inhibits nociception and neurogenic vasodilatation in the trigeminovascular

system by targeting TRPA1 channel S. Materazzi, S. Benemei, C. Fusi, R. Gualdani, G. De Siena (Florence), N. Vastani, D.A. Andersson (London), G. Trevisan, M.R. Moncelli (Florence), X. Wei, G. Dussor

(Tuscon), F. Pollastro (Novara), R. Patacchini (Parma), G. Appendino (Novara), P. Geppetti, R. Nassini (Florence) 17.40-17.50 Visual motion processing areas in chronic migraine patients M. Margoni, F. Maggioni, M. Calabrese, G. Zanchin (Padua) 17.50-18.00 Dramatic remission of intractable SUNCT syndrome by occipital nerve stimulation F. Granella, M. Leccabue, E. Tsantes, F. Pelagatti (Parma), R. Zucco (Reggio Emilia)

HALL 2 16.30-18.00 Oral communications: Case reports Chairs: C.A. Caputi (Ancona), F. Di Sabato (Rome) 16.30-16.40 Sporadic hemiplegic migraine and epilepsy: a new case report in a child A. Capuano (Rome), D. Maiorani (L’Aquila), D. Claps, R. Torriero, S. Tarantino, F. Vigevano, M. Valeriani (Rome) 16.40-16.50 A case of headache in a young female with Sjogren Syndrome and kidney involvement A.M. Marra, V. Villella, G. Granata, I. Molinaro, M. Granata (Rome) 16.50-17.00 Cervicogenic headache during pregnancy: spontaneus spinal epidural haematoma V. Rebecchi, S. Martinenghi, E. Giudici, L. Palma, M. Clerici, G. Bono (Varese) 17.00-17.10 Migraine as the first clinical manifestation of hereditary hemorrhagic telangiectasia in a child E.C. Turco, C. Facini, F. Pisani (Parma) 17.10-17.20 Hemicrania continua with visual aura: first Italian case J. Fantini, A. Granato, F. Trovò, G. Pizzolato (Trieste) 17.20-17.30 Two cases of seizures related to migraine in children A. Capuano (Rome), D. Maiorani (L’Aquila), R. Torriero, F. Vigevano, M. Valeriani

(Rome) 17.30-17.40 Hallucination induced by low dose of topiramate in an emicranic girl: a case report and

a revision of literature C. Lupi, M. Bonciani, S. Benemei, P. Geppetti (Florence) 17.40-17.50 Steroid-responsive headache: main symptom of hypertrophic pachymeningitis a isolated

location of Wegener's granulomatosis E. Ferrante, D. Filippini, M.M. Ferrante, M. Bramerio (Milan) 17.50-18.00 Efficacy of palmitoylethanolamide in a probable paroxysmal migraine F. De Cesaris, S. Benemei, C. Lupi, E. Rossi, A. Chiarugi, P. Geppetti (Florence)

HALL 3 16.30-18.00 Oral communications: Headache in childhood and adolecence I Chairs: E. Del Bene (Florence), A. Verrotti Di Pianella (Perugia) 16.30-16.40 Vit D deficiency, headache and overweight in children: a retrospective analysis D. Maiorani, G. Andrisani, E. Tozzi (L’Aquila) 16.40-16.50 Cardiovascular risk in children and adolescent with migraine V. Tarasco, A. Versace, G. Grasso, R. Pagliero, P. Saracco, E. Castagno, A.F. Urbino

(Turin) 16.50-17.00 Alexithymic characteristics in pediatric patients with primary headaches C. Spitaleri (Palermo), M. Gatta (Padua), U. Balottin (Pavia), A. Spoto (Padua), S. Mangano (Palermo), E. Ferruzza, P.A. Battistella (Padua) 17.00-17.10 Observational study of preventive treatment of migraine in children and adolescents:

preliminary results A. Vecchio, A. Maltese, R. Pitino, D. Trapolino, F. Consolo, V. Raieli, G. Santangelo, F. Vanadia (Palermo) 17.10-17.20 Intellectual functioning and headache in children: the interictal evaluation M. Esposito, G. Patriciello (Naples), B. Gallai (Perugia), L. Antinolfi (Naples), L. Parisi, M. Roccella (Palermo), R. Marotta, S.M. Lavano (Catanzaro), G. Mazzotta

(Terni), M. Carotenuto (Naples) 17.20-17.30 VEP habituation distribution in the families of migraine children S. Pro, S. Tarantino, A. Capuano, C. Casciani, F. Vigevano, M. Valeriani (Rome) 17.30-17.40 Neurofibromatosis type I and migraine in childhood: a new therapeutic perspective M. Carotenuto, G.Patriciello, M. Esposito (Naples) 17.40-17.50 Cognitive profile in new onset headache in children P. Parisi, M.B. De Marco, A. Nicita, F. Marra, A. Ferretti, C. Martini, C. Romano, M.P. Villa (Rome) 17.50-18.00 Children’s headache: drawings in the diagnostic workup S. Mazzotta, E. Pavlidis, C. Cordori, C. Spagnoli (Parma), L.A. Pini (Modena), F. Pisani (Parma)

HALL 4 16.30-18.00 Oral communications: Chronic headaches I Chairs: A. Panconesi (Empoli), E. Sternieri (Modena) 16.30-16.40 Thalamic involvement in migraine chronification process E. Iacovelli (Latina), G. Coppola (Latina/Rome), M. Bracaglia, G. Fragiotta, D. Di Lenola, C. Di Lorenzo, F. Pierelli (Latina) 16.40-16.50 Chronic migraine in the Emergency Department: a two-year prospective study on

efficacy of a dedicated acute Headache Centre A. Granato, J. Fantini, F. Trovò, G. Relja, G. Pizzolato (Trieste) 16.50-17.00 Impact of body mass index on drug consumption in medication overuse patients G. Coppola, C. Di Lorenzo, V. La Salvia, F. Pierelli (Rome) 17.00-17.10 Aggressiveness and impulsiveness in chronic and episodic cluster headache P. Rossi (Grottaferrata), G. Di Lorenzo (Rome), M. Allena, M. Avenali, C. Tassorelli

(Pavia), C. Niolu, A. Siracusano (Rome), G. Nappi (Pavia) 17.10-17.20 Efficacy of a detoxification protocol in medication-overuse headache: report from a

multicentric multinational study C. Tassorelli (Pavia), R. Jensen (Copenhagen), M. Allena, R. De Icco, M. Avenali

(Pavia), Z. Katsarava (Essen), M. Lainez (Valencia), J.A. Leston† (Buenos Aires), R. Fadic (Santiago), S. Spadafora (Buenos Aires), M. Pagani, G. Nappi (Pavia) and the

COMOESTAS Consortium 17.20-17.30 Influence of the type of primary headache on the outcome of medication-overuse

headache following detoxification M. Allena, C. Tassorelli, G. Sances, R. De Icco, G. Sandrini, G. Nappi (Pavia) and the

COMOESTAS Consortium 17.30-17.40 Onabotulintoxin “A” for chronic daily headache: a retrospective cohort study C. Cesaretti, S. Lori, F. Pinto, P. Geppetti, S. Benemei, F. De Cesaris (Florence) 17.40-17.50 Multimodal approach in chronic migraine C. Piro (Foggia) 17.50-18.00 Non-invasive vagus nerve stimulation (nVNS) for acute treatment of chronic migraine

and medication-overuse headache I. Rainero, P. De Martino, E. Rubino, G. Vaula, A. Vacca, S. Gentile, L. Pinessi (Turin)

HALL 5 16.30-18.00 Oral communications: Therapeutic aspects of headache Chairs: R. Iannacchero (Catanzaro), A. Negro (Rome) 16.30-16.40 Comparison of frovatriptan versus other triptans in the acute treatment of migraine with

aura attacks: pooled analysis of double-blind, randomized, cross-over, multicentre, studies

S. Evers (Münster/Coppenbrügge), O. Summ (Münster), M.D. Ferrari (Leiden), L. Savi (Turin), S. Omboni (Varese), C. Lisotto (San Vito al Tagliamento), G. Zanchin

(Padua), D. Zava (Peschiera Borromeo), L. Pinessi (Turin) 16.40-16.50 Efficacy of frovatriptan vs. other triptans in weekend migraine: pooled analysis of three

double-blind, randomized, crossover, multicenter, italian studies L. Savi (Turin), C. Lisotto (San Vito al Tagliamento), L. Pinessi (Turin), S. Omboni (Varese), D. Pezzola, D. Zava (Peschiera Borromeo), G. Zanchin (Padua) 16.50-17.00 Relapse in acute migraine treatment: comparison of frovatriptan with other triptans S. Evers (Münster/Coppenbrügge), O. Summ (Münster), M.D. Ferrari (Leiden), L. Savi (Turin), S. Omboni (Varese), C. Lisotto (San Vito al Tagliamento), G. Zanchin (Padua), D. Zava (Peschiera Borromeo), L. Pinessi (Turin) 17.00-17.10 Dexketoprofen trometamol in the acute treatment of migraine attack: a phase II,

randomized, double-blind, crossover, placebo-controlled, dose optimization study F. Mainardi (Venice), F. Maggioni (Padua), D. Pezzola, D. Zava (Peschiera Borromeo),

G. Zanchin (Padua) 17.10-17.20 Nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen for episodic tension-

type headache: a trial sequential analysis (TSA) E. Rossi, S. Benemei, P. Geppetti, A. Messori (Florence) 17.20-17.30 TDCs treatment: first experience in drug resistant migrainous patients G. Dalla Volta, D. Carli, P. Zavarise (Brescia), G. Zanchin, F. Maggioni (Padua), F. Antonaci (Pavia) 17.30-17.40 Efficacy and tolerability of antiepileptic drugs in epilepsy and migraine diseases S. Siliquini (Perugia), C. Costa (Perugia/Rome), A. Morello, P. Sarchielli (Perugia), P. Calabresi (Perugia/Rome) 17.40-17.50 Diagnostic-rehabilitative pathways in cervicogenic headache, tension-type headache and

migraine: randomized controlled trial between pharmacological and physiotherapy approaches

A. Monticco, R. Marcovich, M. Menegoni, F. Zarattini, M. Segina, J. Fantini, A. Granato (Trieste) 17.50-18.00 Treatment of drug-resistant headache and cranio-facial pain by occipital nerve

stimulation A. Lavano, G. Guzzi, R. Marotta, G. Vescio, F. Deodato, A. Della Torre, F. Lavano

(Catanzaro)

HALL 6 16.30-18.00 Oral communications: Neuroscience and pain Study Group I Chairs: A. Perrotta (Pozzilli), M. Valeriani (Rome)

16.30-16.40 Nocebo effect dissociates the laser-pain rating from the N2/P2 laser evoked potential

amplitude C. Pazzaglia (Milan), E. Testani (Rome), L. Padua (Milan/Rome) M. Valeriani (Rome) 16.40-16.50 Brain activity associated with temporal summation of pain in healthy subjects A. Perrotta (Pozzilli), M. Bolla, R. De Icco (Pavia), M.G. Anastasio (Rome), A. Ambrosini, L. Pavone, F. Izzi, E. Siravo, G. Grillea, M. Bartolo (Pozzilli), G. Sandrini

(Pavia), F. Pierelli (Rome) 16.50-17.00 Peripheral and central nervous contribution to gastrointestinal symptoms in diabetic

patients with autonomic neuropathy M. Valeriani (Rome/Aalborg), C. Brock, C. Graversen, J.B. Frøkjaer (Aalborg), E. Søfteland (Bergen), A.M. Drewes (Aalborg) 17.00-17.10 Heterogeneous phenotypes in a family with Nav 1.7 new mutations V. Tugnoli, V. Simioni (Ferrara), T. Pierro, G. Lauria (Milan) 17.10-17.20 Prevalence and characteristics of neuropathic pain in traumatic brachial plexopathy P. Ciaramitaro (Turin), L. Padua (Rome), G. Devigili (Udine), E. Rota (Piacenza), S. Tamburin (Verona), R. Eleopra (Udine), A. Truini, G. Cruccu (Rome) 17.20-17.30 Pain in stroke patients: characteristics and impact during rehabilitation treatment L. Padua (Rome/Milan), C. Pazzaglia (Rome), F. Cecchi (Florence), I. Aprile (Rome) 17.30-17.40 Sensory profiles in diabetic neuropathic pain: a tool for stratification of patients

according to their underlying pathophysiology? S. Tamburin, F. Magrinelli, M. Praitano, G.C. Peter, M.F. Lauriola (Verona), C. Briani

(Padua), G. Zanette (Verona)

17.40-17.50 Processing of nociceptive input in patients with schizophrenia: preliminary results S. Piroso, A. Fasolina, A. Minichino, G. Di Stefano, A. Biasiotta, S. La Cesa, C. Leone,

A. Pepe, S. Delle Chiaie, G. Cruccu, A. Truini (Rome) 17.50-18.00 Quantification of epidermal nerves by immunofluorescence and bright-field microscopy:

a comparative study M. Nolano (Telese Terme), R. Lombardi (Milan), A. Biasiotta (Rome), V. Provitera, A. Stancanelli (Telese Terme), C. Porretta-Serapiglia (Milan), A. Truini (Rome), G. Lauria (Milan)

ORAL COMMUNICATIONS Saturday, 28 September 2013 University Hospital, School of Medicine PLENARY HALL 12.15-13.13 Oral communications: Clinical aspects of headache II Chairs: A. Palmieri (S. Dona di Piave), P. Rossi (Grottaferrata)

12.15-12.25 Evaluation of migraine comorbidities through clinical and pharmaceutical data A. Panconesi, E. Pavone, C. Pagliai, D. Coletta, N. Mennuti, M.L. Bartolozzi (Empoli),

S. Benemei (Florence), L.Guidi (Empoli) 12.25-12.35 Central sensitivity syndromes and migraine: results of application of an Italian version of

the central sensitization inventory S. Maccora, S. Indovino, V. Raieli, P. Paladino, G. Cosentino, S. Vigneri, B. Fierro, F. Brighina (Palermo) 12.35-12.45 Evaluation of the typical duration of migraine aura: a clinically-based study M. Viana (Pavia), M. Linde (Trondheim), G. Sances, N. Ghiotto, E. Guaschino, M. Allena, G. Nappi (Pavia), P.J. Goadsby (San Francisco), C. Tassorelli (Pavia) 12.45-12.55 Neuropsychological and psychodiagnostic aspects for models of integrated treatment in

patients with chronic headache G. Abbate, F. Brighina, R. Farrauto (Palermo) 12.55-13.05 Headache and genetic thrombophilia. Preliminary results R.L. Trinchi (Trebisacce), M.P. Prudenzano (Bari) 13.05-13.15 Headache as a clinical presentation of brain tumour in adults: results of an

observational, retrospective study C. Marando, C. Costa, S. Siliquini, A. Morello, C. Bedetti, P. Sarchielli, P. Calabresi

(Perugia)

HALL 1 12.15-13.13 Oral communications: Headache in childhood and adolecence II Chairs: M. Carotenuto (Naples), V. Sciruicchio (Bari) 12.15-12.25 Childhood migraine as parental stressor M. Esposito, L. Castaldo, A.R. Montesanto, G. Patriciello (Naples), B. Gallai (Perugia),

L. Parisi, M. Roccella (Palermo), R. Marotta, S.M. Lavano (Catanzaro), G. Mazzotta (Terni), M. Carotenuto (Naples)

12.25-12.35 Alexithymia, headache and eating disorders in childhood and adolescence G. Andrisani, M. Branciaroli, L. Pezzi, D. Maiorani, N. Fiorentini, E. Tozzi (L’Aquila) 12.35-12.45 Migraine with aura in children: a retrospective analysis D. Maiorani (L’Aquila), A. Capuano, R. Torriero, S. Tarantino, F. Vigevano, M. Valeriani (Rome) 12.45-12.55 Headaches and comorbidities in children E. Tozzi, D. Maiorani, G. Andrisani, I. Ciancarelli (L’Aquila) 12.55-13.05 Developmental coordination disorder (DCD) and pediatric migraine: an observational

study M. Ruberto, M. Esposito, A. Mandarino, M. Sorrentino, G. Patriciello, F. Gimigliano, M. Carotenuto (Naples) 13.05-13.15 Migraine in children and adolescents: does a “psychological marker” exist? F. Galli, F. Lionetti, S. Molteni, N. Caime, L. Barone, U. Balottin (Pavia)

HALL 2 12.15-13.13 Oral communications: Chronic headache II Chairs: G. Dalla Volta (Brescia), L. Savi (Turin) 12.15-12.25 Accurate psychiatric preoperative evaluation is needed in patients with chronic

refractory migraine eligible for neurostimulator implantation M. Fiorillo, R. Arcioni, V. Vano, M.R. Del Fiore, P. Martelletti (Rome) 12.25-12.35 Psycopathological aspects in patients with medication-overuse headache I. Corbelli (Perugia), P. Messina (Milan), M. Allena (Pavia), B. Petolicchio (Rome), M.P. Prudenzano (Bari), L.M. Cupini (Rome), A. Russo (Naples), S. Caproni (Perugia),

E. Beghi (Milan), P. Calabresi (Perugia/Rome), P. Sarchielli (Perugia) for the SAMOHA Study Group

12.35-12.45 Short-term psychodynamic psychotherapy versus pharmacological treatment in chronic

headache: an observational study B. Petolicchio, A. Viganò, R. Di Giambattista, M. Squitieri, N. Zanoletti, P. Tortora D’Amato, A. Spensierato, M. Baldassarre, V. Di Piero (Rome) 12.45-12.55 Evaluation of the relationship among patients with chronic headache and partner M.M. Cainazzo, M. De Paola, I. Tiraferri, C. Turrini, A. Bazzocchi, F. Gori, S. Guerzoni, A. Ferrari, L.A. Pini (Modena) 12.55-13.05 Chronic migraine : an observational, retrospective, multicentre study conducted by the

SISC Triveneta Group C. Lisotto (Pordenone), E. Barcaro (Rovigo), P.A. Battistella (Padua), A. Granato

(Trieste), F. Maggioni (Padua), F. Mainardi (Venice), E. Mampreso (Piove di Sacco), M. Mucchiut (Udine), A. Palmieri (Portogruaro), G. Relja (Trieste), I. Toldo (Padua), L. Valentinis (Portogruaro), G. Zanchin (Padua) 13.05-13.15 Chronic headache and medication overuse: analysis of patients and medical

interventions A. Ferrari, E. Sternieri, M.M. Cainazzo, S. Guerzoni, F. Gori, I. Tiraferri, M. Ciccarese,

L.A. Pini (Modena)

HALL 3 12.15-13.13 Oral communications: Latest breaking news in basic science of migraine Chairs: P. Martelletti (Rome), P. Sarchielli (Perugia) 12.15-12.25 Abnormal synaptic morphology and neuronal Ca2+-homeostasis in migraine mutant mice A. Negro (Boston/Rome), K. Eikermann-Haerter, M. Arbel-Ornath, K. Kuchibhotla, E.S. Yu, C. Lattarullo, D. Thyssen, N. Yalcin, I. Rosen, A. Arreguin, M. Climov, F. Keles, A. Belcher, B. Sengul, E. Hudry (Boston), M.D. Ferrari, A.M. van den

Maagdenberg (Leiden), B. Bacskai, C. Ayata (Boston) 12.25-12.35 Changes in glutamatergic neurotransmission within the migraine cycle: evidence by

repetitive transcranial magnetic stimulation (rTMS) G. Cosentino, S. Indovino, S. Maccora, S. Talamanca, S. Vigneri, P. Paladino, R. Baschi,

B. Fierro, F. Brighina (Palermo) 12.35-12.45 A history of migraine accelerates infarct growth in stroke patients A. Negro (Boston/Rome), K. Eikermann-Haerter, K.Y. Park, J. Helenius, L. Pearlman, R. Avery, E.M. Arsava, A. Daneshmand, H. Ay, C. Ayata (Boston) 12.45-12.55 Quadripulse repetitive transcranial magnetic stimulation on visual cortex for chronic

migraine prevention: a pilot-trial T. Sasso D’Elia, A. Viganò (Liège/Rome), S. L. Sava, D. Magis (Liège), V. Di Piero

(Rome), J. Schoenen (Liège) 12.55-13.05 Sleep deprivation enhances susceptibility to cortical spreading depression A. Negro (Boston/Rome), J. Seidel, E.S. Yu (Rome), N. Yalcin, L. Shorser-Gentile, I. Rosen, A. Arreguin (Boston), V. Ramalingam, N. Chamberlin (Boston), P. Martelletti

(Rome), M.A. Moskowitz, C. Ayata, K. Eikermann-Haerter (Boston) 13.05-13.15 Diffuse noxious inhibitory controls are differentially modulated by attention to the pain

intensity and the early electrodermal activity to a laser-heat stimulus A. Viganò (Liège/Rome), I. Maestrini (Rome), V.B. Bogdanov, T. Gavray, Q. Noirhomme (Liège), N. Guy, R. Dallel (Auvergne), A. Colosimo, V. Di Piero (Rome),

J. Schoenen (Liège)

HALL 4 12.15-13.13 Oral communications: Neuroscience and pain Study Group II Chairs: M. de Tommaso (Bari), F. Pierelli (Latina) 12.15-12.25 Laser evoked potentials habituation in irritable bowel syndrome E. Vecchio, G. Cocozza, G. Scianatico, K. Ricci, M. Lorenzo, N. Ranaldo, A. Di Leo, M. de Tommaso (Bari) 12.25-12.35 Neurophysiological study of cutaneous silent period in demyelinating and axonal

polyneuropathies D. Lopergolo, E. Onesti, G. Tartaglia, M. Gabriele (Rome), B. Isak (Istanbul), V. Frasca,

M. Inghilleri (Rome) 12.35-12.45 Spinal direct current stimulation is able to modulate the temporal summation of pain at

spinal level in healthy subjects M. Bolla (Pavia), A. Perrotta, A. Ambrosini (Pozzilli), F. Pierelli (Rome), G. Sandrini

(Pavia) 12.45-12.55 Usefulness of the association of laser evoked potentials and skin biopsy for the diagnosis

of neuropathic pains with similar clinical presentation and different pathophysiological mechanisms: two case reports

M. Buonocore, R. Bagnasco, A. Gatti, L. Demartini, C. Bonezzi (Pavia) 12.55-13.05 Circadian hyperactivity of the lower limb nociceptive system in idiopathic restless legs

syndrome: a co2 laser evoked potential study C. Vollono, G. Della Marca, E. Testani, D. Ferraro, D. Virdis (Rome), D. Le Pera

(Modena), R. Miliucci, P.M. Rossini (Rome), M. Valeriani (Rome/Aalborg)

13.05-13.15 Botulinum toxin for muscle cramps associated with diabetic neuropathy: a double-blind, placebo-controlled study

D. Restivo, M. Romano, R. Spidalieri, D. Gullo (Catania)

POSTER SESSION POSTER EXHIBITION AREA Friday, 27 September, 2013 Poster Session: Clinical aspects of headache I Chairs: D. Cassano (Nocera Inferiore), F. Mongini (Turin) 1 Temporary aphasia in migraine with aura L. Savi, R. Totaro, C. Condello, M. Tirassa, L. Pinessi (Turin) 2 Fatigue and migraine without aura: a study investigating occurrence and correlation with the

main descriptors of disease S. Gori, C. Lucchesi, F. Baldacci, A.N. Sassi, U. Bonuccelli (Pisa) 3 Photophobia is associated with allodynia during migraine without aura attack F. Baldacci, C. Lucchesi, M. Ulivi (Pisa), M. Vedovello (Bergamo), A. Vergallo, M. Giuntini (Pisa), A. Nuti (Viareggio), U. Bonuccelli, S. Gori (Pisa) 4 Migraine and epilepsy: comorbidity or “ictal epileptic headache”? P. Parisi, F. Marra, C. Martini, C. Romano, M.P. Villa (Rome) 5 Headache in the elderly: disease or symptoms of disease? The fine line between primary and

secondary headaches as a diagnostic problem especially in Emergency G. Arosio, A. Mandelli, A. Russo, M. Galbussera, P. Merlo (Bergamo) 6 Cluster headache in the elderly is more common in women than in men C. Lisotto (Pordenone), F. Mainardi (Venice), F. Maggioni, G. Zanchin (Padua) 7 Borderline personality, anxiety-mood disorders and migraine: clinical implications D. Cassano, A. Amato, G. D’Onofrio, M.R. Porcaro, A.M. Romano (Nocera Inferiore), V. Pizza

(Vallo della Lucania), V. Busillo (Eboli), C. Colucci D’Amato (Naples) 8 Adjustment and pre-existing psychiatric disorders prevalence among headache patients

accessing to a pain clinic in southern Italy A. Costa, F. Migliazza, O. Marotta, R. Iannacchero (Catanzaro) 9 The compliance of migrainous patients: is there a role for Attention-Deficit Disorder detecting

Brown Scale? L. Savi, C. Condello, L. Pinessi (Turin) 10 Headache care objectives and outcomes in a tertiary centre in the Italian Region of Calabria R. Iannacchero, O. Marotta, F. Migliazza, A. Costa, U. Cannistrà (Catanzaro)

Poster Session: Clinical aspects of headache II Chairs: C. Di Lorenzo (Latina), S. Gori (Pisa) 11 Headache in Emergency settings: assessing diagnosis accuracy for neurology outpatient

services E. Pucci, S. Bruscella, G. Sandrini (Pavia) 12 Disability in migraine: are motherhood and pregnancy a side of the dice? C. Martini, M. Fuccaro, F. Maggioni, G. Zanchin (Padua) 13 The Cephalalgic Day Service: quantitative approaches for planning and management of clinical

services R. Guido, D. Conforti, M.C. Groccia, B. Corasaniti (Cosenza), R. Iannacchero (Catanzaro) 14 Unilateral or bilateral migraine pain: does it affect migraine clinical picture? C. Lucchesi, F. Baldacci, A.N. Sassi, M. Ulivi (Pisa), A. Nuti (Viareggio), U. Bonuccelli, S. Gori (Pisa) 15 Headache, migraine and epilepsy: a proposal of terminology in relation to the possible

associations C. Cianchetti, D. Pruna, M.G. Ledda (Cagliari) 16 Correlation between allodynia and migraine severity R. Iannacchero, O. Marotta, A. Costa, F. Migliazza (Catanzaro) 17 Is patent foramen ovale a co-morbidity of migraine with aura? A combined and simultaneous

sonography study with related MRI findings V. Annese, M. Turazzini, R. Del Colle, A. Lupato (Verona), L. Sartorelli (Legnago), A. Polo

(Verona) 18 ARTe Cluster Project: cluster headache - from pain to inspiration… P. Rossi (Grottaferrata), C. Geraci, F. Mesa Navarro (Alleanza Cefalalgici Cluster) 19 Communication and the headache patients: social and deontological aspects G. Iannone, C. Piccolini, A. Sensidoni, S. Carletti (Terni)

Poster Session: Case reports Chairs: A. Cervarolo (Cosenza), F. Maggioni (Padua) 20 A case of cluster headache treated with rotigotine: clinical and neurophysiological correlates M. Bracaglia, C. Di Lorenzo, G. Coppola, F. Pierelli (Rome) 21 Bilateral cluster headache: a case report A. Autuori, S. Siliquini, I. Corbelli, P. Sarchielli (Perugia), P. Calabresi (Perugia/Rome) 22 Idiopathic intracranial hypertension: a case report D. Cassano (Nocera Inferiore) 23 Idiopathic pseudotumor cerebri: is it a benign condition? R. Torriero, A. Capuano, S. Tarantino, F. Vigevano, M. Valeriani (Rome) 24 Atypical presentation of ophthalmoplegic migraine in adult A. Di Vincenzo, C. Tana, E. Tafuri, E. Cozza, G. Di Pietro, C. Massacesi, M. Basci, A. Fabrizio, G. Affaitati, A. Mezzetti, M.A. Giamberardino (Chieti) 25 Recurrent headaches and "incidental findings" on brain MRI: to wait or to intervene? B. Bolzonella, D. De Carlo, I. Toldo, S. Sartori, M. Gatta, M. Calderone, P.A. Battistella

(Padua) 26 Cavernous sinus dural arteriovenous fistula successfully treated with coil embolization: case

report M. Trucco, R. Padolecchia, R. Schizzi, L. Bruzzone (Pietra Ligure) 27 ONS and chronic cluster headache: a case report A. Tarsitano, F. Amato (Cosenza) 28 A combination of occipital and supraorbital neurostimulation for the treatment of refractory

chronic migraine: a case report F. Marsibilio, M. Fiorillo, V. Vano, L. D’Alonzo (Rome)

Poster Session: Headache in childhood and adolecence Chairs: A. Capuano (Rome), D. Moscato (Rome) 29 Epidemiological and clinical features of pediatric migraine in a tertiary centre V. Tarasco, G. Grasso, A. Versace, E. Castagno, A.F. Urbino, R. Pagliero (Turin) 30 Evolution of headache in childhood: prognostic factors and clinical features B. Bellini, F. Lucchese, E. Salvi, V. Guidetti (Rome) 31 Sleep habits and subjective daytime somnolence in pediatric migraine M. Esposito (Naples), M. Roccella, L. Parisi (Palermo), B. Gallai (Perugia), I. Della Valle, D. Avolio, G. Patriciello, M. Carotenuto (Naples) 32 Motion sickness in childhood migraine: the efficacy and safety of Griffonia

simplicifolia/Magnesium complex M. Esposito, G. Patriciello, M. Della Vedova, M.A. Faraldo, M. Carotenuto (Naples) 33 Attachment style and psychological symptoms in headache children: is there a relationship with

maternal attachment and alexithymia? S. Tarantino, C. De Ranieri, M.F. Paniccia, A. Capuano, F. Vigevano, S. Gentile, M. Valeriani

(Rome) 34 Clinical features, anger management and anxiety: a possible correlation in migraine children S. Tarantino, C. De Ranieri, C. Dionisi, M. Citti, A. Capuano (Rome), F. Galli (Pavia), V. Guidetti, F. Vigevano, S. Gentile, F. Presaghi, M. Valeriani (Rome) 35 Obesity and headaches in children E. Salvi, A. Lo Noce, A. Antonelli, P. Verdecchia, V. Guidetti, D. Brkic, S. Simeoni (Rome) 36 Attachment styles and migraine without aura in pediatric age A. Di Dona, M. Esposito, I. Di Salvatore, G. Patriciello (Naples), M. Roccella (Palermo), M. Carotenuto (Naples) 37 Chronic headaches in children and in adolescents: cases series of a Juvenile Headache Center P.A. Battistella, D. De Carlo, I. Toldo, S. Sartori, B. Bolzonella, M. Gatta (Padua) 38 Chronic primary headaches in children and adolescents referred to two third level headache

centres A. Capuano (Rome), B. Bartoli (Varese), R. Torriero, R. Mariani, F. Vigevano (Rome), C. Termine (Varese), M. Valeriani (Rome) 39 Airplane headache: report of two cases in pediatric age D. De Carlo, B. Bolzonella, I. Toldo, S. Sartori, M. Gatta, G. Zanchin, P.A. Battistella (Padua) 40 Headache secondary to cardio and cerebrovascular disorders in children and adolescents: our

experience M. Monti, C. Copioli, T. Piroddi, C. Zammarchi, M.R. Gullì (Rimini) 41 Pharmacological treatment of primary headaches in children: a multicentre Italian study I. Toldo, M. Rattin, D. De Carlo, B. Bolzonella, E. Perissinotto, S. Sartori (Padua), L.N. Rossi

(Milan), A. Vecchio (Palermo), A. Simonati (Verona), M. Carotenuto (Naples), C. Scalas (Florence), V. Sciruicchio (Bari), V. Raieli (Palermo), G. Mazzotta (Perugia), U. Ballottin (Pavia), E. Tozzi (L’Aquila), M. Valeriani (Rome), C. Cianchetti (Cagliari), V. Guidetti (Rome), P.A. Battistella (Padua)

Poster Session: Chronic headaches Chairs: M. Trucco (Pietra Ligure) M. Viana (Pavia) 42 Cognitive neuropsychological psychotherapeutic treatment in chronic migraine L. Ruiz (Alessandria), C. Lanni (Pavia), C. Prevost, M. Mascolo, E. Ursino, D. Ferrandi

(Alessandria) 43 Chronic migraine: an observational, prospective, multicenter study conducted by the SISC

Triveneta Group C. Lisotto (Pordenone), E. Barcaro (Rovigo), P.A. Battistella (Padua), A. Granato (Trieste), F. Maggioni (Padua), F. Mainardi (Venice), E. Mampreso (Piove di Sacco), M. Mucchiut

(Udine), A. Palmieri (Portogruaro), G. Relja (Trieste), I. Toldo (Padua), L. Valentinis (Portogruaro), G. Zanchin (Padua)

44 Psychological profile in patients with medication-overuse headache and alcohol dependence:

are there differences? S. Guerzoni, M.M. Cainazzo, M. De Paola, M. Ciccarese, A. Bazzocchi, F. Gori, A. Ferrari

(Modena) 45 The impact of chronic migraine on the quality of life and on the National Health System in a

population of patients attending a 3rd level headache centre R. De Icco, M. Bolla, M. Allena, M. Avenali, G. Sances, S. Cristina, M. Berlangieri, E. Berra, N. Ghiotto, E. Guaschino, C. Tassorelli, G. Nappi, G. Sandrini (Pavia) 46 Clinically-orientedstratified approach and patient-preference approach in the management of

MOH – A comparison between two strategies P. Rossi (Grottaferrata/Pavia), C. Tassorelli (Pavia), J.V. Faroni (Grottaferrata), G. Nappi

(Pavia) 47 Chronic headache, a new therapy F. Ottaviani, M. Cuomo, D. Cacciola, L. Martini, L. Pandolfi, S. Papadopoulou, N. Pusceddu

(Rome) 48 Treatment of chronic migraine by means of vagal stimulator D. Moscato, F.R. Moscato (Rome)

Poster Session: Therapeutic aspects of headache Chairs: R. Iannacchero (Catanzaro), F. Mainardi (Venice) 49 Monitoring the use of symptomatic drugs in headache: a population study F. Antonaci, I. De Cillis, L. Gervasio, C. Fattore, M. Bianchi (Pavia), C. Voiticovschi-Iosob

(Pavia/Chisinau), G. Nappi (Pavia) 50 Pilot study on the use of palmietanolamide (PEA) in a group of patients with migraine without

aura G. Dalla Volta, D. Carli, P. Zavarise, G. Ngonga (Brescia) 51 Benefits of a preliminary assessment for treatment with topiramate in patients at risk for

cognitive disorders: the Frontal Assessment Battery C. Piccolini, G. Iannone, A. Sensidoni, S. Carletti (Terni) 52 Warfarin efficacy in migraine without aura but not in exertional headache F. Maggioni, M. Margoni (Padua), F. Mainardi (Venice), C. Lisotto (San Vito al Tagliamento),

G. Zanchin (Padua) 53 TINER therapy in headaches of patients with obstructive sleep night apneas D. Di Nicola (L'Aquila), A. Lera (Giulianova) 54 TINER therapy in family members with headaches of patients affecteds by epilepsy A. Lera (Giulianova) 55 Efficacy of a workplace physical and educational program on muscle tenderness in a working

community with headache and neck pain: a longitudinal, controlled study E. Rota, F. Mongini, A. Evangelista, G. Ciccone, C. Galassi, C. Milani, L. Ferrero, A. Ugolini

(Turin) 56 Surgical treatment for headache: personal procedure G. Caruana, E. Grignaffini, L. Quarta, N. Bertozzi, E. Raposio (Parma)

Poster Session: Neuroscience and pain Study Group Chairs: S. Tamburin (Verona), V. Tugnoli (Ferrara) 57 Warmth and nociceptive evoked potentials in Crisponi Syndrome E. Testani, C. Vollono, G. Della Marca,G. Zampino (Rome), M. Valeriani (Rome/Aalborg) 58 Cortical changes induced by focal mechanical vibration on nociceptive pathways C. Pazzaglia (Milan), C. Vollono, F. Camerota, C. Celletti, E. Testani (Rome), L. Padua

(Milan/Rome), M. Valeriani (Rome) 59 Pain in postsurgical orthopedic rehabilitation: a multicentre study L. Padua (Milan/Rome), I. Aprile (Rome), F. Cecchi, R. Molino Lova (Florence), M.F. Arezzo,

C. Pazzaglia (Rome) 60 Lack of habituation of evoked visual potentials in analytic information processing style:

evidence in healthy subjects F. Di Sabato, M. Buonfiglio (Rome), G. Avanzini (Milan), M. Toscano, F. Puledda, L. Di Clemente, V. Di Piero (Rome) 61 A clinical and neurophysiological study of pain in patients with Ehlers Danlos syndrome A. Biasiotta, G. Busto, C. Celletti, G. Di Stefano, C. Leone, S. La Cesa, S. Piroso, A. Pepe, G. Cruccu, M. Castori, F. Camerota, A. Truini (Rome) 62 Pain in a complex case of polyneuropathy and possible schwannomatosis M. Lacerenza, S. Gabrielli, L. Manfredi, F. Mancini, A. Bianchi (Milan), S. Gerevini, L. Papi (Florence) 63 Clinical, neurophysiological and skin biopsy study of painful neuropathy associated with HCV

related-cryoglobulinaemia S. La Cesa, A. Biasiotta, G. Di Stefano, C. Leone, S. Piroso, A. Pepe, M. Casato, C. Giordano,

G. D’Amati, A. Truini, G. Cruccu (Rome) 64 Point prevalence study of multiple myeloma induced-peripheral neuropathy A. Pepe, P. Viana, R. Labriola, C. Leone, S. La Cesa, G. Di Stefano, A. Biasiotta, S. Piroso, V. Federico, C. Cartoni, M.T. Petrucci, G. Cruccu, A. Truini (Rome) 65 Diabetic small fibre neuropathy diagnosis: a comparison between the diagnostic accuracy of

skin biopsy and laser evoked potentials G. Di Stefano, A. Biasiotta, C. Leone, S. La Cesa, S. Piroso, A. Pepe, G. Cruccu, A. Truini

(Rome) 66 Paroxysmal pain is mediated by non-nociceptive large myelinated fibres. A neurophysiological

study in normal humans C. Leone, E. Galosi, G. Di Stefano, S. La Cesa, A. Biasiotta, A. Pepe, S. Piroso, G. Cruccu, A. Truini (Rome)

TEACHING COURSE FOR CHILD AND ADOLESCENT NEUROPSYCHIATRISTS, PAEDIATRICIANS AND PSYCHOLOGISTS Headaches in children: from theory to clinical practice Perugia, 28 September 2013 Coordinators: P.A. Battistella (Padua), G. Castellucci (Perugia) V. Guidetti (Rome), G. Mazzotta (Terni) PLENARY HALL 9.00-9.30 Magistral Lecture "Giovanni Lanzi" Presentation: V. Guidetti (Rome) Headache and psychiatric comorbidity in children and adolescents U. Balottin (Pavia) HALL 5 9.30-13.30 Part I Chairs: P.A. Battistella (Padua), G. Mazzotta (Terni) 9.30-10.15 Features and Limitations of the IHS classification B. Gallai (Perugia) 10.15-11.00 Genetics of migraine: up date A. Persico, M. Verdecchia (Rome) 11.00-11.45 The approach to the headache patient in the emergency room  A.A. Niccoli (Spoleto) 11.45-12.00 Coffee Break 12.00-12.45 The "dangerous" headaches: red flags and diagnosis G. Mazzotta (Terni) 12.45-13.30 The instrumental analysis: when and how to make them E. Tozzi (L’Aquila) 13.30-14.30 Lunch

14.15-17.30 Part II: Interactiv case reports - Presentation of clinical cases Chairs: V. Guidetti (Rome), M. Morlupo (Spoleto) 14.15-14.45 Case Report I P.A. Battistella (Padua) 14.45-15.15 Case Report II G. Di Cara (Perugia) 15.15-15.45 Case Report III V. Guidetti (Rome) 15.45-16.15 Case Report IV M. Carotenuto (Naples) 16.15-16.45 Case Report V C. Termine (Varese) 16.45-17.15 Case Report VI R. Torriero (Rome) 17.15 –17.30 CME Test

TEACHING COURSE FOR GENERAL PRACTITIONERS Headaches in clinical practice Perugia, 28 September 2013 Coordinators: G. Bono (Varese), P. Sarchielli (Perugia) T. Scarponi (Perugia) HALL 6 9.00 Introduction G. Bono (Varese), T. Scarponi (Perugia) 9.30-10.00 Session I: The approach to the patient: diagnostic criteria and essential paths Chairs: I. Rainero (Turin), G. Zanchin (Padova) 9.30-10.00 Primary headaches L. Savi (Turin) 10.00-10.30 Secondary headaches F. Devetag (Feltre) 10.30-13.00 Session II: Guidelines for the treatment Chairs: M. de Tommaso (Bari), V. Di Piero (Rome) 10.30-11.00 The attack therapy C. Di Lorenzo (Rome) 11.00-11.30 Prophylaxis interventions F. Mainardi (Venice) 11.30-12.00 Headache in the Emergency Department G. Bono (Varese) 12.00-12.30 The integrated management of the patient: the relationship between the General

Practitioner and the Specialist G. Duranti (Perugia) 12.30-13.00 Hub and Spoke Management Model: the headache network R. Iannacchero (Catanzaro) 13.00-14.00 Session III: Open issues Chairs: M.P. Prudenzano (Bari), M. Fanciullacci (Florence) 13.00-13.30 Chronic headache: a diagnostic and therapeutic challenge A. Ferrari (Modena) 13.30-14.00 Headache disorders and comorbid problems and opportunities C. Lisotto (Pordenone) 14.00-15.00 Lunch

15.00-17.00 Session IV: Case reports Chairs: M. Alessandri (Grosseto), C. Costa (Perugia) 15.00-15.20 Case reports I L. D’Alonzo (Rome) 15.20-15.40 Case reports II I. Corbelli (Perugia) 15.40-16.00 Case reports III A. Autuori (Perugia) 16.00-16.20 Case reports IV S. Siliquini (Perugia) 16.20-16.40 Caso clinico V L. D’Alonzo (Rome) 16.40-17.00 Discussion 17.00 CME Test

SPEAKERS AND CHAIRS Massimo Alessandri – Grosseto Federico Mainardi – Venezia Anna Ambrosini – Pozzilli Monica Margoni - Padova Fabio Antonaci – Pavia Paolo Martelletti – Roma Roberto Arcioni – Roma Giovanni Mazzotta – Perugia Alessia Auturoi – Perugia Franco Mongini - Torino Umberto Balottin – Pavia Maurizio Morlupo - Spoleto Pier Antonio Battistella – Padova Davide Moscato - Roma Ettore Beghi - Milano Giuseppe Nappi - Pavia/Roma Silvia Benemei - Firenze Rossella Elena Nappi - Pavia Giorgio Bono - Varese Andrea Negro - Boston, USA/Roma Filippo Brighina - Palermo Antonio Augusto Niccoli - Spoleto Maria Gabriella Buzzi - Roma Ferdinando Nicoletti – Roma Paolo Calabresi - Perugia Antonio Palmieri – S. Dona di Piave Stefano Caproni – Perugia Stefano Palmisani - Londra, UK Alessandro Capuano - Roma Alessandro Panconesi – Empoli Claudio Antonio Caputi – Ancona Antonello Persico - Roma Antonio Carolei - L’Aquila Armando Perrotta - Pozzilli Marco Carotenuto - Napoli Francesco Pierelli - Latina Andrea Castelnuovo – Torino Daniela Pietrobon - Padova Giuseppe Castellucci - Perugia Lorenzo Pinessi - Torino Domenico Cassano - Nocera Inferiore Luigi Alberto Pini – Modena Rosanna Cerbo - Roma Stefano Pro - Roma Antonino Cervarolo - Cosenza Maria Pia Prudenzano – Bari Gianluca Coppola - Latina Vincenzo Raieli - Palermo Ilenia Corbelli - Perugia Innocenzo Rainero – Torino Pietro Cortelli - Bologna Aroldo Rossi - Perugia Cinzia Costa - Perugia Paolo Rossi – Grottaferrata Giorgio Cruccu - Roma Simona Sacco – L'Aquila Giorgio Dalla Volta - Brescia Elisa Salvi - Roma Lidia D'Alonzo – Roma Giorgio Sandrini - Pavia Marina de Tommaso – Bari Paola Sarchielli - Perugia Enrico Del Bene - Firenze Lidia Savi – Torino Maria Del Zompo – Cagliari Tiziano Scarponi - Perugia Flavio Devetag - Feltre Jean Schoenen – Liège, Belgio Giuseppe Di Cara - Perugia Vittorio Sciruicchio – Bari Cherubino Di Lorenzo – Latina Sabrina Siliquini - Perugia Vittorio Di Piero - Roma Emilio Sternieri – Modena Francesco Di Sabato – Roma Stefano Tamburin - Verona Giuliana Duranti - Perugia Cristina Tassorelli – Pavia Marcello Fanciullacci - Firenze Gioacchino Tedeschi – Napoli Anna Ferrari – Modena Cristiano Termine - Varese Beatrice Gallai - Perugia Roberto Torriero - Roma Federica Galli - Pavia Riccardo Torta - Torino Pierangelo Geppetti – Firenze Elisabetta Tozzi - L'Aquila Roberto Gerli - Perugia Marco Trucco - Pietra Ligure Maria Adele Giamberardino – Chieti Andrea Truini - Roma Sara Gori - Pisa Valeria Tugnoli - Ferrara Franco Granella - Parma Massimiliano Valeriani - Roma Vincenzo Guidetti - Roma Alberto Verrotti Di Pianella - Perugia Rosario Iannacchero – Catanzaro Michele Viana - Pavia Marco Ruggero Lacerenza - Milano Giorgio Zanchin - Padova Carlo Lisotto - Pordenone Ferdinando Maggioni - Padova -