physioex 2 act 1and2

8/20/2019 Physioex 2 Act 1and2

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Introduction

• Skeletal muscles are connected to the skeletonto form part of the mechanical system thatmoves the limbs and other parts of the body.

• Physiological skeletal muscle contractionrequires generation and spread of a membraneaction potential, transduction of the electrical

energy into an intracellular chemical signalthat, in turn, triggers myolament interaction.


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Introduction

• Force Transducers are also commonlykno!n as Force Sensors . It is dened asa transducer that converts an input

mechanical force into an electrical outputsignal.

• In this e"periment an isolated skeletalmuscle is isolated and !as mounted on a

force transducer to generate musclecontractions !ith controlled electricalstimulations.


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%b&ective' To Identify and measure duration of the latent

period

To understand' (lectrical stimulus

e"citation)contraction coupling

*uscle t!itch

+atent period

ontraction phase

-ela"ation phase


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Skeletal muscle


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+atent period did not change !hendi/erent voltages of stimulus !ereapplied

) in bet!een muscle stimulation andbeginning of muscle response

-ole of acetylcholine

-elease at end)plate potential


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• %b&ective'

– Identify treshold stimulus

– 1nderstand'

2o! motor unit recuitment can increase the tension a!hole muscle develops

2o! Increasing stimulus voltage to an isolatedmuscle in an e"periment


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Skeletal muscle


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• Stimulus voltage directly proportionalon the amount of active force – *ore bers and motor neurons are

activated

• #t ma"imal voltage, all muscle bershad generated there ma"imal force

thus they are all depolari3ed and aresuccessfully recruited.

physioex 2 act 1and2

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