[premoney sf 2015} sos ventures >> sean o'sullivan, "accelerating biology: producing...

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Confidential - Copyright 2015 Premoney 12 June 2015 Accelerating Biology Producing Milk Without Cows, Egg Whites Without Chickens, THC Without Pot (What It Means for the Planet...& the Market) @indbio - @sosventures

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Confidential - Copyright 2015

Premoney 12 June 2015

Accelerating BiologyProducing Milk Without Cows, Egg Whites Without Chickens, THC Without Pot (What It Means for the Planet...& the Market)

@indbio - @sosventures

Confidential - Copyright 2015

Synthetic biology & biodesign

San Francisco & Cork

Who we are: SOSV - the Accelerator VC

SOSventures is the Accelerator VC

China/Asia - Software/Apps

Chinaccelerator

InteractionX

Human-computer interaction. .

Hardware/Robotics/IOTShenzhen, China.

Hax FoodX

“Disruptive Food”New York

Hardware Distribution

Boost

Vertical theme-based accelerators

Deep domain expertise & hands-on,

supportive model

Eternal spring of high quality investment

opportunities

Concentrated in Key Areas / Megatrends

De-risk with long and effective due diligence process

@indbio - @sosventures

SOSV: Accelerating Biology

IndieBio

Confidential - Copyright 2015

130 companies graduate SOSV accelerators per year

SOSventures is the Accelerator VC

• IndieBio

• Hax

• FoodX

40

30

20

20

10 • Other

• Chinaccelerator

HealthMaterialsFood

‘A new way for scientists, entrepreneurs, and

makers to shape their own destiny

and make something that

matters’

1/3 of accelerator portfolio

@sosventures@indbio - @sosventures

SOSV: Accelerating Biology

Confidential - Copyright 2015

BioSystems

IndieBio teams fall into 2 main buckets

SOSventures is the Accelerator VC

Grow milk in vats rather than in cows.

M

The Nespresso machine of DNA

synthesis

Producing ex-vivo egg whites without chickens

Growing rhino horns from DNA and 3D

printed keratin

“Lab on a Chip” : $10 real time blood

diagnostics

Synthetic Biology

@indbio - @sosventures

SOSV: Accelerating Biology

Confidential - Copyright 2015

What is biology?

SOSventures is the Accelerator VC

Think: “Engineered lifeforms”

@indbio - @sosventures

SOSV: Accelerating Biology

“The study of animals and plants…”

What is synthetic biology?

Confidential - Copyright 2015

That was then…

SOSventures is the Accelerator VC

@indbio - @sosventures

SOSV: Accelerating Biology

Feedstock Organism Output Yummy

Confidential - Copyright 2015

SOSventures is the Accelerator VC

this is now.

@indbio - @sosventures

SOSV: Accelerating Biology

Feedstock Organism Yummy

Confidential - Copyright 2015

Then: resource intensive

SOSventures is the Accelerator VC

Raw Inputs Plant/Animal Raw output

@indbio - @sosventures

SOSV: Accelerating Biology

Confidential - Copyright 2015

Now: Resource Efficient, Scalable

SOSventures is the Accelerator VC

Develop organisms

Ferment feedstock Purify

@indbio - @sosventures

SOSV: Accelerating Biology

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Data Processing

@indbio - @sosventures

SOSV: Accelerating Biology

Input Data Programs Output

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Bioprocessing

@indbio - @sosventures

SOSV: Accelerating Biology

Data = Feedstock

Programs =DNA

Output =Desired Protein/

Molecules/Chemicals

Confidential - Copyright 2015

$40m Series B

SOSventures is the Accelerator VC

?

VCs

production

@indbio - @sosventures

SOSV: Accelerating Biology

Last week: Bolt Threads w/ $40m funding round

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Fundable Categories in the new Biotech

@indbio - @sosventures

SOSV: Accelerating Biology

Synthetic BiologyOutput materials: chemicals, compounds, foods, materials, drugs, etc.

BioSystems ToolsPicks & Shovels: bioreactors, robotics, process improvements, DNA printers, Crisper CAS9, etc.

cloud biolabs, bioprocessing plants, yield improvement services, info services

Biomedical DesignBiotreatments & drug discovery: therapeutic applications, new treatment methods.

BioSystems Infrastructure

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Fundable Categories in the new Biotech

@indbio - @sosventures

SOSV: Accelerating Biology

Synthetic BiologyOutput materials: chemicals, compounds, foods, materials, drugs, etc.

Grow milk in vats rather than in cows.

M

Producing ex-vivo egg whites without chickens

Growing rhino horns from DNA and 3D

printed keratinNext generation microbes for

industrial chemicalsProduction of THC without

production of Marijuana plants

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Fundable Categories in the new Biotech

@indbio - @sosventures

SOSV: Accelerating Biology

BioSystems Tools

The Nespresso machine of DNA

synthesis

“Lab on a Chip” : $10 real time blood

diagnostics

Sub $1,000 bioreactor

Sub $2,000 liquid handling robot

Picks & Shovels: bioreactors, robotics, process improvements, DNA printers, Crisper CAS9, etc.

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Fundable Categories in the new Biotech

@indbio - @sosventures

SOSV: Accelerating Biology

cloud biolabs, bioprocessing plants, yield improvement services, info services

BioSystems Infrastructure

Predictive DNA analysis, processing every possible variant

Bioprocessing optimization

Cloud services for bioprocessing

Github for life sciences

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Fundable Categories in the new Biotech

@indbio - @sosventures

SOSV: Accelerating Biology

Biomedical DesignBiotreatments & drug discovery: therapeutic applications, new treatment methods

The Solution for Gaucher’s Disease

A sustainable supply for Horseshoe Crab Blood

Diagnostic DNA computer for tropical diseases

Crowdsourced bacteria for drug discovery

Confidential - Copyright 2015

SOSventures is the Accelerator VC

Regulatory Issues

@indbio - @sosventures

SOSV: Accelerating Biology

US vs. Europe

What’s a GMO?

Biosimilar

Orphan Diseases

Confidential - Copyright 2015

Growing rhino horns from DNA and 3D

printed keratin

Producing ex-vivo egg whites without chickens

The Nespresso machine of DNA analysis

Representative SOSventures Indie.Bio Investments

Grow milk in vats rather than in cows.

SOSventures is the Accelerator VC

“Lab on a Chip” : $10 real time blood diagnostics

M

SOSv: Accelerating Biology

@indbio - @sosventures