Program8thAnnualRetreat

Graduiertenkolleg1202

jointlyorganizedwithCPCResearchSchool

„Oligonucleotidesincellbiologyand

therapy“

June13thand14th,2013

Ohlstadt,HotelAlpenblick

12:00–13:00 Lunch

13:00–14:00 SessionV“Tumorimmunotherapy”(chair:YiZeng)

13:00–13:15 ChristopherLampert:BispecificantibodiesandTcellsforcancertherapy

13:15–13:30 AnjaFunk:ExploitingRIG‐Isignalingandgenesilencingforimmunotherapyofhepatocellularcarcinoma

13:30–13:45 HannaMeinl:BifunctionalimmunoactivesiRNAsasanapproachtopersonalizedAMLtherapy

13:45–14:00 TinaAdunka:EffectiverestoringofCD4+andCD8+TcellresponsesthroughinhibitionofsecretedTGF‐βbypancreaticductaladenocarcinoma(PDAC)

14:00–14:30 Coffeebreak

14:30–14:45 Resumeofthe8thAnnualRetreat

15:00 TripbacktoMunich

Day1:Thursday,June13

th2013

09:00–09:30Check‐inHotelAlpenblick

09:30–09:45Welcome(SpeakerProf.Endres,Prof.Rothenfußerfortheorganizers)

09:45–10:45SessionI“SignalinginCancer”(chair:MoritzRapp)

09:45–10:00NataschaKüpper:ImpactofIL‐22oncoloncancer

10:00–10:15DanielWenk:RegulationofIL‐22inamurinecancermodel

10:15–10:45SaskiaGraf:SOX10promotesmelanomacellinvasionandregulatesmelanomainhibitoryactivity(MIA)

10:45–11:15Coffeebreak

11:15–12:00SessionII“InnateImmunity”(chair:MarcoWachowius)

11:15–11:30MaximilianGradel:AroleforLgp2intherecognitionofviralRNPs

11:30–11:45SofiaAnton:Unchartedterritory‐transcriptionalregulationofRIG‐I‐likehelicasepromoters

11:45–12:00CharlotteLässig:SecondarystructurepredicitionofMeaslesVirusRNA

12:00–13:00Lunch

13:00–13:30BrainstormlastGrakoRetreat2014

13:30–18:00Sparetime:

triptoStaffelsee/Murnau(trainthere14:26andback17:36)or

hikeupKäseralmfromOhlstadt(3to4hoursroundtrip)orvisittheSchloßmuseumMurnauBringtheappropriategeartojoinintheseactivities!

18:00–19:00Dinner

19:00–20:00Prof.OliverEickelberg:Novelmechanisms,biomarkersandtherapeuticinterventionsinlungfibrosis

20:00–openend

Hotelbar

Day2:FridayJune14th2012

08:30–09:00Breakfast

09:00–10:00SessionIII“Tcells”(chair:QihuiZhou)

09:00–09:15MaximilianWintergerst:Regulatorytcell‐dendriticcellcontactsasmediatorofimmunesuppression

09:15–09:30ChristophFreier:Novelregulatorytcellattractingchemokines

09:30–09:45FaustoPirronello:PlasticityofinflammatoryCD4Tcellsubsetsinhumanautoimmunedisease,rheumatoidarthritis

09:45–10:00SonjaHaupt:Treg‐specificGARPexpressionisdependentonepigeneticmodificationsandFoxp3

10:00–10:30Coffeebreak

10:30–12:00SessionIV“Immune‐relateddiseases”(chair:ChristophFreier)

10:30–10:4510:45–11:0011:00–11:3011:30–12:00

FalkBatz:TheroleofIRF4inchronicrenaldiseasesSimoneRomoli:TheinnateimmunityeffectsonprogenitorstemcellsTheresaKäuferle:MicroRNAregulationofmTOR–nutrientsignalingduringadipocytedifferentiationChristinaGramlich:TheinfluenceofYadA‐collagenbindingonYersiniapathogenesis