psychiatry simplified for medical students (dsm iv-tr)
TRANSCRIPT
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PSYCHIATRY
Ida
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Content
Title Page Number
Psychiatric Evaluation 2iaison Psychiatry !
Personality "isorders #$
Stress "isorders #%
Childhood "isorders #&
Eating "isorders 2'
Substance Abuse 2%
Schi(o)hrenia* "e)ression and +i)olar ,ood "isorder '%
Suicide and "eliberate Sel-.harm $2
An/iety "isorders $!
Pregnancy.related "e)ression $0
Cognitive "isorders !1
Psychotro)ic treatment !0
EPS and N,S %
,alaysian Psychiatry %0
Note: This book follows the diagnostic criteria from DSM-IV-TR
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Psychiatric evaluation
3no4ing the )atient
Predis)osing -actor 4hy did the )atient develo) this disorder5
signi6cant -amily history
)ersonality disorder or traits
traumatic childhood e/)eriences
chronic stress
substance use
Preci)itating -actor
4hy develo) at this )oint in time5
Protective -actor
4hat are the -actors that 4ill hel) him recover5
good social su))ort
good )re.morbid level o- -unctioning
good insight
early intervention
no substance use including alcohol no criminal behaviour
Per)etuating -actor
4hat are the -actors that may )revent him -rom
getting better5
)oor social su))ort
)oor )re.morbid level o- -unctioning )oor insight
late treatment
co.morbid substance use
criminal record
unem)loyment
,ental State E/amination
A))earance and behaviour
Abnormal behaviour
+uilt
Cleanliness* consciousness* coo)eration
"istractibility* dressing
Eye contact
7acial e/)ressions
S)eech
anguage s)o8en Ade9uate
Coherent
Relevant
Com)rehension o- s)eech
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,ood and A:ect
Current mood
abile mood
Congruent a:ect
Thought content
"elusions
;bsessions
Concerns
Suicidal thoughts
"e)ressive thoughts
Phobias
Perce)tion
Hallucinations
Illusions
Cognitive -unctions
orientation to time* )lace and )erson
memory< immediate =immediate recall o- ! ob>ects?*
recent =recall the ! ob>ects a-ter ! minutes* eventsthat ha))ened last 2$ hours?* remote =IC number*
address?
Attention and concentration< serial * @;R"
bac84ards
Abstract reasoning and concrete thin8ing< e/)lain a
)roverb* similarities bet4een table and chair
eneral 8no4ledge< ca)ital city o- ,alaysia*
Inde)endence "ay
Budgment< in a burning house* burglar in the house
Insight< a4areness* attribution and acce)tance o-condition
Physical e/amination
. to rule out medical causes -or the sym)toms
. to chec8 -or side e:ects -rom )sychiatric medications
. to loo8 -or co.morbid medical disorders
,ultia/ial diagnosis
A/is I< Psychiatric disorder
A/is II< "evelo)mental or )ersonality disorder
A/is III< eneral ,edical condition
A/is I< Presence o- ongoing )sychosocial stressors
A/is < lobal Assessment o- 7unctioning
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iaison )sychiatry
Classi6cation o- )sychiatric illness encountered in
liaison setting
. Psychiatry )rovo8ing ill.health
. Psychiatry as conse9uence o- organic disease
. )sychiatric sym)toms as )resenting sym)toms
. cerebral com)lications o- organic disease
. abuse o- alcohol and drugs
. deliberate sel-.harm
. se/ualDrelationshi) )roblems and eating disorders
. )sychiatric disorder e/acerbate )hysical illness
. )hysical sym)toms 4ithout organic basis
. )sychiatric and )hysical illness occurring by chance
iaison case summaries
. reason -or re-erral
. )sychiatric diagnosis
. )hysical disease and )atients reaction to it
. evidence o- abnormal illness behaviour
. relationshi) bet4een the )sychological and )hysical
as)ects o- the case
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. )atients )ersonality co)ing strategies
. )atients attitude to4ards )sychiatric intervention
. sta: attitude to4ards )atient
Psychiatric disorder in )hysical illness
7actors a:ecting )revalence o- )sychiatric disorder in
)hysical illness
Illness
sym)toms
threat to li-e
course =acute* rela)sing* chronic?
duration
disability
cons)icuousness
Treatment
nature
side.e:ects
uncertainty o- outcome
need -or sel-.care
Patient
)sychological vulnerability
social circumstances
other stresses =chronic and acute?
reactions o- others
7actors associated 4ith a )articularly high ris8 o-
)sychiatric )roblems
Severe illness
un)leasant
threatening
acute rela)sing or )rogressive illness
Fn)leasant treatment
ma>or surgery
radiothera)y
chemothera)y
ulnerable )atients
history o- )revious )sychiatric )roblems
current )sychiatric disorder
adverse social circumstances lac8 o- )ersonal and emotional su))ort
Im)lications -or assessment
Characteristics o- Gat.ris8G )atients
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systematic revie4 o- )atients* loo8ing -or )sychiatric
)roblems
)resence o- 8ey sym)toms
in-ormation -rom relatives
im)lications -or treatment
A:ective disorder
. 4orsens )rognosis o- stro8e and ,I
Positive )sychological changes
. enhanced a))reciation o- li-e
. less concern -or trivial or material things
. more tolerance to4ards others
. im)roved sel-.4orth
Sic8 role
. sic8 individual is obliged to see8 the a))ro)riate hel)*
coo)erate 4ith assessment* acce)t a diagnosis and com)ly
4ith the treatment
. legitimate ado)tion o- this role re9uires sanction -rom
relatives* medical )ractitioners* em)loyers and others in
authority
Illness behaviour
. describes the actions o- the )atient and his attitude
to4ards medical )ersonnel
. eg stoical* restrained* histrionic* dramati(ing* hostile*
sus)icious* irtatious* )leading* aloo-* e/cessively
coo)erative and agreeable
Abnormal illness behaviour
. uncom-ortable a4areness o- bodily events much o- the
time together 4ith e/cessive -ears and concerns about
health and disease
. relentless search -or causes and cures cou)led 4ith
inability to acce)t reassurance -rom doctors even 4hen this
has been given clearly )lus a))ro)riate investigation done
. inability to acce)t the suggestion that non.)hysical
-actors may be relevant to ones condition
. disability out o- )ro)ortion to detectable organic disease
. rein-orcement o- illness behaviour by -amily* disability
)ayments and health care )roviders
. ina))ro)riate res)onse to )hysical disorder . either
e/cessive disability or denial o- need o-
treatmentDlimitation o- activities
. ado)tion o- li-estyle around the sic8 role 4ith re)ertoire o-behaviours to sustain sic8 role
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"e)ression
Ris8 -actors -or de)ressive disorders in )hysical illness
. -emale gender
. being unmarried
. living alone
. )revious de)ressive e)isodes
. certain medical treatments
. severe -orms o- )hysical illness
"e)ression in )hysically ill
. co.morbid disorders continue a-ter discharge
. o-ten goes undetected
. de)ressive disorders co.occurring 4ith )hysical illness
com)licate treatment o- both disorders
. )redicts readmission
. )ost)oning treatment o- de)ressive disorder 4orsens
)rognosis o- both
. high healthcare costs
. )oor 9uality o- li-e
Possible mechanism o- co.morbidity
. e:ect on neurotransmitters
. e:ect on immune system
. side e:ects o- medications
. )hysical se9uelae o- suicide attem)ts
. )ossible common genetic )redis)osition
Post.stro8e de)ression
. u) to !1 o- )atients develo) )ost.stro8e de)ression in
acute )ost.stro8e )eriod
Ris8 -actors -or )ost.stro8e de)ression
. le-t anterior brain lesions =es)ecially caudate nucleus?
. dys)hasia
. living alone
. )ast history o- ma>or de)ressive e)isodes
. )revious history o- )yschiatric andDor cerebrovascular
disorder
. -amily history o- mood disorders
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An/iety
. causes increased vulnerability to cardiac events
. )hobic an/iety and generalised an/iety are )redictors o-
,I and cardiac death
Antici)atory an/iety
. )er)etuates the disability
;rganic an/iety syndromes
. cardiovascular system< angina* arrhythmia* congestive
cardiac -ailure
. endocrine system< hy)erthyroidism* )haeochromocytoma*meno)ause
. metabolic disorders< hy)oglycemia* hy)o/ia
. neurologic disorders< sei(ure disorder* a8athisia
. gastrointestinal system< )e)tic ulcer disease
. res)iratory system< asthma* C;P"
. immunologic disorder< ana)hyla/is* SE
,edications that cause an/iety.li8e sym)toms
Stimulant into/ication< ca:eine* nicotine* cocaine*
metam)hetamines* )hencyclidine
Sym)athomimetics< )seudoe)hedrine*
methyl)henidate* am)hetamines* beta agonists
"o)aminergics< amantadine* bromocri)tine*
levodo)a
Anticholinergics< ben(tro)ine* di)henhydramine*
me)eridine
,iscellaneous< e)hedrine* indomethacine*
steroids
"rug 4ithdra4al< alcohol* +"J* o)iates
Cancer
. )sychological im)act o- diagnosis de)ends on the 4ay the
disease )resents
. im)act is greater i- cancer is detected une/)ectedly in an
a))arently healthy )erson
. uncertainty 4hen )atient 6rst comes to clinic may be so
stress-ul that they develo) an/iety 4hile 4aiting -or the
investigation results
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,eaning o- cancer to the )atient. loss o- )hysical strength and 4ell being
. loss o- inde)endence
. loss o- role
. loss o- )ersonal relationshi)s
. loss o- li-e e/)ectancy
. loss o- control . the younger )atient* the greater the
im)act
"evelo)ment o- emotional )roblems
. no )sychiatric disorder< !1
. ad>ustment reaction< '1
. -ormal )sychiatric diagnosis< 21
7actors contributing to )sychological )roblems. concern about )rognosis and 4el-are o- relatives
. )oorly controlled )hysical sym)toms eg )ain* nausea*
breathlessness
. vulnerable )ersonality . )oor co)ing 4ith stress
. direct e:ects o- illness to the brain
. side e:ects o- drugs
. metabolic disturbances such as liver -ailure
. -ear o- being abandoned as the disease )rogresses
. lac8 o- con6ding relationshi)s
. other li-e events or diKculties not related to cancer
Prevention o- emotional )roblems
. o:er in-ormation about illness and its treatment . may be
re)eated later
. allo4 the )atient to e/)ress emotional distress
. )rovide ongoing care
"etection o- emotional )roblems
. sim)le screening 9uestionnaire re)eated at regular
intervals
. as8 )atient -rom time to time ho4 they have been co)ing
4ith the emotional side o- illness and let them discuss theircurrent concerns
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An/iety
. may be mi/ed 4ith de)ression
. around time o- initial diagnosis and 4hile 4aiting -or
results -or sus)ected rela)se
Ris8 -actors -or an/iety
. harbouring underground -ears about illness or its
treatment and too -rightened to share 4ith the sta:
. see8s out more in-ormation than they can handle
. inaccurate in-ormation -rom non.medical )ro-essionals
. )ersonality
E:ect o- an/iety on cancer treatment
. chronically an/ious )atients 4ould consult doctors
-re9uently and become hy)ochondriacal once the diagnosis
is con6rmed
. -alse alarms about s)read o- disease
. very concerned about treatment and its side e:ects
. avoidance o- treatment
. may 8ee) their sym)toms a secret* resulting in a delayed
diagnosis
. inter-ere 4ith treatment and diagnostic test
"enial
. unconscious re-usal to ac8no4ledge certain distressing
as)ects o- reality
. to )rotect themselves -rom an/iety and un)leasantness in
daily li-e
. usually lasts not more than a -e4 days
Sus)ect denial 4hen
. reactions
. loo8s -or another )hysician in the ho)e o- getting aGbetter e/)lanationG
. as8s -or re)eated investigations* )artially 8no4ing that
the original diagnosis is correct
. -ail to reali(e their diagnosisD)rognosis
. -ails to as8 9uestions about the illness
. -orgets the in-ormation given
. ma8ing unrealistic )lans -or the -uture
. understands the matters in intellectual sense 4ithout
a))ro)riate emotional distress
Ada)tive denial
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. denial acts as a bu:er a-ter une/)ected ne4s* allo4ing
)atient to collect himsel- and mobili(e other resources
. denial is a tem)orary de-ense and 4ill be re)laced by
)artial acce)tance
. it enables )atients to ac8no4ledge their cancer andacce)t necessary treatment at one level o- conscious
a4areness
. at another level they )lay do4n the seriousness o- the
illness
. they may tal8 briey about the reality o- their situation
be-ore indicating their inability to loo8 at it realistically any
longer =daydream* -antasies* tal8ing about brighter things
4hich contradict 4hat he said earlier?
,alada)tive denial
. delays cancer diagnosis
. )oor com)liance
. bloc8ed communication 4ith relatives
,anagement o- denial
. Collusion
going along 4ith the )atients vie4
8ind to the )atients but the sta: -eels uncom-ortable
. Con-rontation
challenging the )atient 4ith the truth
sta: -eels better but causes great distress to the
)atient
. ,iddle a))roach
am)le o))ortunity -or )atient to as8 9uestions but
never -orcing un4anted in-ormation u)on them
Anger
. transient anger is a normal )hase in the ad>ustment
)rocess
. some )atients may obtain relie- through the s)ontaneous
-ree e/)ression o- anger be-ore they move on to4ards
acce)tance
. -amily and nurses 6nd it hard to co)e because anger is
dis)laced at all directions and )ro>ected at random
. anger can be more mar8ed in the relatives
. sta: or -amily member should not react )ersonally
because it -eeds into the )atients hostile behaviour
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Ty)es o- anger
. -ree oating< angry about the un-airness o- the illness*
blaming -ate or od
. dis)laced< to4ards healthcare sta:
. >usti6ed< delay in ma8ing diagnosis
. su))ressed< not co.o)erative and leads to de)ression
@hy anger5
. com)aring sel- 4ith others . limited activity
. as8ing -or attention to ma8e sure that he is not -orgotten
. loss o- control
,anagement o- anger
. listen to )atient* donLt be de-ensive and donLt ma8e
>udgments
. o:er consistent )ro-essional care although the )atient is
ungrate-ul
. -acilitate a -ull blo4n e/)ression o- anger by a neutral
counsellor
. res)onding to criticisms o- other doctors and nurses
. colluding 4ith the blame on colleagues is un4ise and
un-air
. encourage redirection o- anger and re.chanelling the
energy else4here eg e/ercise* music* creative activity and
cancer.related charity 4or8
. medication< )sychotro)ics
"e)ression in cancer
. usually associated 4ith a great sense o- loss
. 6nancial burden
. loss o- >ob due to -re9uent absences or inability to
-unction
. drugs< cytoto/ics* steroids
Clinical )resentation
. )hysical sym)toms seem to be out o- )ro)ortion to thestage o- cancer )rogression eg 4eight loss* anore/ia*
-atigue
. insomnia es)ecially morning a4a8ening
. an/iety
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. diKcult to control )ain
. suicidal thoughts
Ty)es o- de)ression
. reactive de)ression
encouragements and reassurances
. )re)aratory grie-
ta8es into account im)ending losses
allo4 )atient to e/)ress their sorro4
E:ect on cancer treatment. )atient may consider themselves too 4orthless to get
hel)
. they do not com)lain
. )oor 9uality o- li-e
,anagement o- de)ression
. let )atient e/)ress their -eelings o- sadness and anger
. -oster a 6ghting s)irit* but i- )atient is very de)ressed* it
can accentuate the sense o- shame and -ailure
. i- de)ression )ersists a-ter sim)le discussion* more
s)ecialised treatment such as )sychothera)y and
antide)ressants 4ill be re9uired
Acce)tance. a stage 4here the )atient is neither de)ressed nor angry
about his -ate
. almost void o- -eelings
. as i- the struggle is over
. )atient )re-ers to be le-t alone
. not in a tal8ative mood
. communications become more non.verbal than verbal
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Personality "isorders
CFSTER A< ;dd
Paranoid
. Sus)icious* sensitive* mistrust-ul* resent-ul* sel-.im)ortant
Schi(oid
. Cold* detached* lac8 en>oyment* intros)ective
Schi(oty)al
. socially an/ious* cognitive and )erce)tual distortions*
oddities o- s)eech* ina))ro)riate a:ective res)onse*
eccentric behaviour
CFSTER +< "ramatic
Antisocial
. ac8 o- concern -or others -eelings* transient
relationshi)s* irres)onsible* im)ulsive and irritable* lac8
guilt and remorse* -ail to learn -rom adverse e/)erience
Social learning in childhood -or antisocial behavior
. through gro4ing u) in an antisocial -amily
. through lac8 o- consistent rules in the -amily
. learnt as a 4ay o- overcoming another )roblem
. -rom )oor ability to sustain attention and other
im)ediments to learning
+orderline
. Identity disturbance* intense unstable relationshi)s*
e:orts to avoid abandonment* recurrent suicidal behavior*transient stress.related )aranoid ideation* im)ulsive*
diKculty controlling anger* unstable a:ect* history o-
conduct disorder be-ore #!
Histrionic
. Sel-.dramati(ation* suggestible* shallo4 and labile a:ect*
see8s attention and e/citement* ina))ro)riately seductive*
over.concerned 4ith )hysical attractiveness* e/cessively
im)ressionistic s)eech* considers relationshi)s moreintimate than they are
Narcissistic
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. randiose sel-.im)ortant* e/)loits others* re9uires
e/cessive admiration* envious and e/)ects to be envied*
lac8s em)athy
CFSTER C< An/ious
Avoidant
. -eels socially in-erior* )reoccu)ied 4ith )ossibility o-
re>ection* avoids involvement 4ith ne4 e/)eriences and
)eo)le* avoid ris8* avoid social activity* restraint in intimate
relationshi) -rom -ear o- being shamed or ridiculed*
inhibited in ne4 )ersonal situations due to -eelings o-
inade9uacy
"e)endent
. Allo4s others to ta8e res)onsibility* unduly com)liant 4ith
4ishes o- others* -eels unable to care -or themselves* -ear
o- being le-t to care -or themselves* diKculty initiating
)ro>ects* goes to e/cessive lengths to obtain su))ort*
urgently see8s a su))ortive relationshi)
;bsessive.com)ulsive
. Preoccu)ied 4ith detailsDrules* inhibited by )er-ectionism*
over.conscientious* e/cessively concerned 4ith
)roductivity* rigid and controlling* miserly* cannot discard
4orthless or 4orn.out ob>ects
;THERS
Passive.aggressive
. Passive resistance 4hen given demands -or ade9uate
)er-ormance
"e)ressive
. Persistently gloomy* strong sense o- duty* little ca)acity
-or en>oyment* unsatis6ed 4ith their li-e
Hy)erthymic
. Habitually cheer-ul and o)timistic* )oor >udgement* >um)s
to conclusion* )eriods o- irritability
Cycloid
. E/tremes o- de)ressive and hy)erthymic )ersonality
disorders
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Stress "isorders
Acute stress reaction
. 7ree(e* 6ght* ight
. Avoidance and denial should recede as an/iety diminishes
to allo4 coming to terms 4ith the stress-ul e/)erience
Acute stress disorder
. onset 4hile or a-ter e/)eriencing the distressing event
. asts M2 days but $ 4ee8s
. co)ing strategy< avoidance o- reminders* use o- alcohol or
drugs
. de-ence mechanisms< denial* dis)lacement* regression
"iagnosis
. stressor
e/)osure to event involving actualDthreatened
deathDserious in>ury to sel- or others e/)erience o- -earDhel)lessnessDhorror or
disorgani(edDagitated behaviour in children
. sym)toms
re.e/)eriencing o- the event
avoidance o- stimuli that arouse recollections o- the
trauma
mar8ed sym)toms o- an/iety or hy)erarousal
signi6cant distress or im)aired social -unctioning
M' o-< sense o- numbingDdetachment* reduced
a4areness o- surroundings* dereali(ation*
de)ersonali(ation* dissociative amnesia
,anagement
. assess by acute stress disorder intervie4* acute stress
disorder scale. Critical incident stress debrie6ng< -acts* thoughts*
-eelings* assessment* education
.reassurance that the condition is -re9uent and short.lived
.short.term an/iolytic =i- an/iety is severe? and hy)notic =i-
severely disru)ted slee)?
.7ollo4.u) 4ithin # month
. )revention< cognitive behavioural intervention 2.4ee8s
)ost.trauma* )re)are individuals at ris8 =eg E,S andmilitary? by training to remain calm and ob>ective* avoid
identi-ying 4ith victims* e/)ress emotional reactions
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PTS"
. traumatic event< e/)erienced* 4itnessed or con-ronted
4ith an event that involved actual or threatened death or
serious in>ury or a threat to the )hysical integrity o- sel- orothers
. etiology< -ear conditioning* hy)othalamic.)ituitary.adrenal
a/is abnormalities* or adrenergic e:ect on amygdala
. )re.dis)osing -actors< 4omen* -amily history o- )sychiatric
disorder* )ersonal history o- mood and an/iety disorder*
)revious history o- trauma* lo4er intelligence* lac8 o- social
su))ort
. signi6cant distress or im)aired social -unctioning -or M#
month
. re.e/)erience by M# o-
ashbac8s
dreams
trauma re.enactment
distress or reactivity to cues resembling an as)ect o-
the event
. avoidance o- reminders by M' o-
thoughts
activities
inability to recall
reduced interest
numbness
restricted a:ect
sense o- -oreshortened -uture
. hy)erarousal by M2 o-
insomnia
irritability
)oor concentration
hy)ervigilance
e/aggerated startle res)onse
. assess by clinician.administered PTS" scale =gold
standard? or )ost.traumatic stress diagnostic scale
. management< counselling* C+T* i- )atient )re-ers or i-
)sychothera)y unavailable then give SSRI or TCA and
continue -or a year i- good res)onse
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Childhood disorders
Attention.de6citDhy)eractivity disorder
. )attern o- diminished sustained attention and higher
levels o- im)ulsivity in a child or adolescent than e/)ected
-or someone o- that age and develo)mental level
. more )revalent in boys
. attention.de6cit disorder< )ersistent -or at least % months
o- M % sym)toms o-
-ailing to give close attention to details or ma8es
careless mista8es in activities*
o-ten has diKculty sustaining attention in tas8s or
)lay activities*
o-ten does not seem to listen 4hen s)o8en to
directly*
o-ten does not -ollo4 through on instructions and
-ails to 6nish chores*
o-ten has diKculty organi(ing tas8s*
o-ten avoidsDdisli8esDreluctant to engage in tas8s
that re9uire sustained mental e:ort*
o-ten loses things necessary -or tas8s*
o-ten easily distracted by e/traneous stimuli* o-ten
-orget-ul in daily activities
. hy)eractivity disorder< )ersistent o- at least % months o-
M % sym)toms o-
o-ten 6dgets 4ith handsD-eet or s9uirms in seat* o-ten leaves seat in situations in 4hich remaining
seated is e/)ected*
o-ten runs about or climbs e/cessively in situations
in 4hich it is ina))ro)riate*
o-ten has diKculty )laying or engaging in leisure
activities 9uietly*
o-ten Gon the goG or acts as i- Gdriven by a motorG*
o-ten tal8s e/cessively
. some sym)toms that caused im)airment 4ere )resent
be-ore years old
. cognitive testing including a continuous )er-ormance tas8
=the child is as8ed to )ress a button each time a )articular
se9uence o- letters or numbers ashes on the screen?
. 6rst.line management< CNS stimulants methyl)henidate
and de/troam)hetamine
. second.line management
nore)ine)hrine u)ta8e inhibitor Atomo/etine*
antide)ressant venla-a/ine*
al)ha.adrenergic rece)tor agonist clonidine
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Autism
. 9ualitative im)airment in social interaction* im)airment in
communication* restricted re)etitive and stereoty)ed
)atterns o- behaviourDinterests
. due to neuroanatomical or biochemical -actors
. onset ' years o- age o- delays or abnormal -unctioning
in M # area =social interaction* language used in social
communication* symbolic or imaginative )lay?
. total o- M % items 4ith
M2 -rom 9ualitative im)airment in social interaction
lac8 o- eye contact* -acial e/)ression and gestures*
no -riends*
lac8 o- social and emotional reci)rocity
M # -rom 9ualitative im)airments in communication
delay or lac8 o- develo)ment o- s)o8en language*
diKcult to initiate and sustain a conversation* stereoty)e and re)etitive use o- language or
idiosyncratic language
M# o- restricted* re)etitive and stereoty)ed )atterns o-
behaviourDinterestDactivities
adherence to s)eci6c routines or rituals*
stereoty)ed and re)etitive motor mannerisms
. more -re9uent in boys
. associated 4ith congenital rubella* )henyl8etonuria*
tuberous sclerosis
. may be due to immunological incom)atibility 4ith mother
=maternal antibodies directed at -etus? or )erinatal
com)lications
. management< target behaviours that 4ill im)rove their
abilities to integrate into schools* develo) meaning-ul )eer
relationshi)s and increase the li8elihood o- maintaininginde)endent living as adults
Retts syndrome
. )rogressive condition o- develo)mental deterioration 4ith
onset a-ter several months o- a))arently normal
develo)ment
. a))arently normal )renatal and )erinatal develo)ment
. a))arently normal )sychomotor develo)ment through the
6rst ! months a-ter birth
. normal head circum-erence at birth
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. onset o- all o- the -ollo4ing a-ter the )eriod o- normal
develo)mentor de)ressive e)isode M# 4ee8
Ra)id cycler< M$ mood s4ings in # year
Treatment -or mania
sodium val)roate*
olan(a)ine*
chlor)roma(ine* halo)eridol*
9uetia)ine*
ari)ira(ole*
ris)eridone*
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ECT
Treatment -or de)ression
SSRI 7luvo/amine
amotrigine*
o-e)ramine =A;I" i- suicidal?*
ECT
,aintenance
lithium*
carbama(e)ine =es) ra)id.cycling?
lamotrigine
High ris8 clinical -actors -or suicide includeor de)ressive disorder but tend toe/)erience more mood uctuation and )rominent an/iety
sym)toms
. "isinterest in the ne4born D -ear-ul o- being le-t alone 4ith
the baby
. Increased ris8 o- suicide* neglect o- the ne4born and
in-anticide
. Treatment includes antide)ressants 7luo/etine =SSRI? or
"othie)in =TCA?* ECT and )sychothera)y
. Ris8 o- recurrence is !1
Post)artum )sychosis
. ;nset usually 4ithin the 6rst month
. usually in )rimi)arous or 4hen there is a history o-
)erinatal com)lications
. Early stages similar to )ost)artum blues* )rogress to
-ran8 )sychosis 4ith sus)iciousness* delusions*
hallucinations 4hich may involve the child
. may have im)ulses to harm the child
. agitated* )oor slee)
. Treatment includes ECT* anti)sychotics 4ith mood
stabili(ers i- bi)olar in )resentation and anti)sychotics 4ith
antide)ressants i- de)ressed
. Advice on non.hormonal contrace)tion
. Ris8 o- recurrence is 1
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Cognitive disorders
"elirium
. Acute global cognitive im)airment in the setting o-
clouded consciousness =)atient is a4a8e but has reduced
a4areness o- environment and is unres)onsive?
. o-ten reversible and brie-
Predis)osing -actors
age M%!*
male*
cognitive im)aired =dementia* de)ression?*
-unction im)airment =-unctional de)endence*
immobility?*
sensory im)airment*
decreased oral inta8e*
substance use*
coe/isting medical conditions
Preci)itating -actors
drugs =narcotics* )oly)harmacy?*
)rimary neurological disease*
intercurrent illness*
surgery*
environmental =)hysical restraint* ICF admission*
multi)le )rocedures?
Patho)hysiology
cholinergic de6ciency*
do)amine =regulates acetylcholine?*
changes in +++
"iagnosis
disturbance o- consciousness 4ith reduced ability to
-ocus* sustainDshi-t attention*
change in cognition or develo)ment o- )erce)tual
disturbance*
develo)ment o- disturbance over a short )eriod o-
time =hours to days? and uctuates
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Ty)es
"elirium due to a general medical condition
=evidence -rom history* PE or laboratory 6ndings? egmeningitis* head in>ury* stro8e* FTI* chest in-ection*
PE* ,I* arrhythmia* he)atic ence)halo)athy*
hy)erDhy)oglycemia in diabetes* e)ile)sy*
malignancy
delirium due to into/ication =sym)toms develo)ed
during substance into/ication* medication use is
etiologically related to the disturbance* cognitive
sym)toms are in e/cess o- into/ication syndrome? eg
insulin* digo/in* lithium* o)iates* ben(odia(e)ines
delirium due to substance 4ithdra4al =sym)toms
develo)ed during or shortly a-ter a 4ithdra4al
syndrome* cognitive sym)toms in e/cess o-
4ithdra4al syndrome?*
delirium due to multi)le etiology*
delirium not other4ise s)eci6ed
Investigations
"elirium Rating Scale evaluates tem)oral onset o-
sym)toms* uctuation* )erce)tual disturbances andhallucinations*
Con-usion Assessment ,ethod tool =re9uires acute
onset and uctuating course 4ith inattention and
either disorgani(ed thin8ing or altered level o-
consciousness?
Abbreviated ,ental Test Score to establish cognitive
de6cits )resent on admission and -or a baseline
score -or assessing )rogress
Non.)harmacological management
avoid e/tremes o- sensory in)ut*
relie- o- distress*
control agitation and )revent e/haustion*
)sychosocial su))ort
Pharmacological management
ensure drug treatment -or underlying )hysical
)roblem is the minimum re9uired
anti)sychotics -or agitated )atients 4ith )erce)tual
disturbances*
treatment o- s)eci6c etiologies
"ementia
. global im)airment o- intellect 4ithout im)aired
consciousness
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. cognitive -unctions a:ected include memory* orientation*
)erce)tion and attention* >udgment* language and )roblem
solving and abstract thin8ing
. score o- 2' out o- '1 in ,,SE is suggestive o- cognitive
im)airment
. inter-eres 4ith social and occu)ational -unctioning
. )atients may have e)isodes o- violence or abuse to4ards
others and sel-.harm in advanced dementia
. )atients are vulnerable to )hysical* mental and 6nancial
abuse by others
Reversible causes o- dementia
Hy)othyroidism
it +#2 de6ciency
Subdural haematoma Fremia
Normal )ressure hydroce)halus
Sy)hilis
Irreversible causes o- dementia
Al(heimers disease
ascular dementia
AI"S
Ouestions to elicit ty)e o- memory diKculties
+eing more -orget-ul5
osing your train o- thought5
Problems trying to 6nd the right 4ord5
"iKculty -ollo4ing conversations5
7orgetting to turn things o: such as the lights or
stove5
3ee)ing trac8 o- time5
;thers e/)ressing concern about your memory5
7unction
$ instrumental activities o- daily living
. As8 caregiver 4hether )t needs assistance in these areasugate ga(e disorder are ty)ical?
. Thiamine de6ciency may be secondary to alcoholism*
vomiting during )regnancy* dietary insuKciency or gastric
carcinoma
. Treatment is 4ith urgent intravenous thiamine* but the
ma>ority 4ill develo) a chronic 3orsa8o: syndrome
Creut(-eldt.Bacob disease
. characteri(ed by a ra)idly )rogressive dementia*
myoclonus and distinctive electroence)halogra)hic and
neuro)athologic 6ndings
. The in-ectious agent causing CB" is uni9ue in being a
con-ormationally abnormal )rion )rotein ie contains no
genetic material
. The dementia can be accom)anied by signs o-
involvement o- any )art o- the central nervous system* but
myoclonus is )articularly common
. Although ty)ically occurring s)oradically in middle.aged
adults* a -amily history may be )resent in &.#1
. variant CB" in young adults has been lin8ed 4ith
e/)osure to bee- in-ected 4ith the bovine s)ongi-orm
ence)halo)athy agent This ne4 variantL -orm o-ten
)resents 4ith an e/tended neuro)sychiatric )rodrome 4ithmood disturbance or other )sychiatric sym)tomatology
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Secondary causes o- dementia
. ,etabolic< thiamine de6ciency* vitamin +#2 de6ciency*
hy)othyroidism* Cushings syndrome* @ilsons disease
. ascular< Cerebrovascular disease* subdural haematoma
. Neo)lastic< )rimary CNS tumours* metastases
. Inammatory< SE
. "rugs and to/ins< Anticholinergics* heavy metal e/)osure
. In-ection< Sy)hilis
Elderly Cognitive Assessment Ouestionnaire
. A score o- or more is indicative o- normal memory and a
score o- $ and belo4 indicate )robable dementia This is
use-ul -or routine screening
,,SE
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. This is the most 4idely used instrument -or assessing
severity o- the dementia Ho4ever it can only assess the
domains o- cognitive de6cit The ma/imum score is '1 The
lo4er the score* the more severely demented the )atient
is
eriatric "e)ression Scale
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. A short #!.item 9uestionnaire is used to assess the
de)ression in dementia The )atient has )ossible
de)ression i- the score is ! or more
Cloc8 dra4ing test
. This is used as a measure o- constructional a)ra/ia and
may also reect -rontal and tem)oro)arietal -unctioning
lobal "eteroration scale
. -or staging o- dementia
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Stage # NormalStage 2 ery mild
,emory )roblem re)orted but not evident in
clinical intervie4Stage ' ,ild im)airment in memory* concentration
and occu)ational )er-ormance
Stage $ ,oderate im)airment in memory* 8no4ledgeretrieval and com)lete tas8s
Stage ! ,od to severe im)airment in recent and
remote memory* -re9uent disorientation to
time and )lace* im)airments o- A"Stage % Severe cognitive im)airment 4ith inability to
tend to A" 4ithout assistanceStage ery severe im)airment in cognition*
language and motor s8ills
,anagement o- dementia
Eliminate non.essential drugs that could inter-ere
4ith cognition
,onitor driving ability and sa-ety in use o- household
a))liances
Re-er to local A" Association -or in-ormation and
su))ort grou)s
eneral treatmento su))ortive medical careo emotional su))ort -or )atient and -amily
o Provide an environment that )rovides -re9uentcues -or orientation
o Su))ortive thera)y U grou) thera)y
Sym)tomatic treatment
o nutritious diet* )ro)er e/ercise* attention to
visual and auditory )roblems
Pharmacological treatment -or s)eci6c sym)toms
Psychotro)ic treatment
Psychoeducation
. )sychothera)eutic intervention
. educate the )atient and their -amilies about the illness*
the cause and course o- the illness and the role o-
medication
. hel)s im)rove )atients insight* com)liance* lo4er rate o-
rela)se and better sym)tom control
. enhances su))ort -rom -amily members
Cognitive +ehavioural Thera)y
. a 4ay o- tal8ing about ho4 you thin8 about yoursel-* the
4orld and other )eo)le and ho4 4hat you do a:ects your
thoughts and -eelings. hel)s to change ho4 you thin8 =Cognitive? and 4hat you
do =+ehaviour?
. -ocuses on the here and no4 )roblems and diKculties
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. Instead o- -ocusing on the causes o- your distress or
sym)toms in the )ast* it loo8s -or 4ays to im)rove your
state o- mind no4
. re9uires commitment and coo)eration -rom the )atient
. )rovides the )atient 4ith s8ills to a))roach -uture
)roblems
. ma8e sense o- over4helming )roblems by brea8ing them
do4n into smaller )artsected to )hysical means o- restraint or seclusion
in )sychiatric hos)itals
The )rivacy and sa-ety o- a )atient shall be observed
at all times during the restraint or seclusion
)rocedures
No )hysical or chemical means o- restraint or
seclusion shall be a))lied to )atients in any)sychiatric nursing home or community mental
health centre* e/ce)t during an emergency and the
)atient shall then be trans-erred to )sychiatric
hos)itals 4ithout delay
I- the )eriod o- )hysical means o- restraint o- a
)atient e/ceeds eight hours* a )sychiatrist shall
revie4 the )atient on the need -or -urther restraint
No seclusion shall be carried out on a )atient -or
more than eight hours consecutively or -or more
than t4elve hours intermittently over a )eriod o-
-orty eight hours* 4ithout an inde)endent revie4 bya )sychiatrist
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Restraint area
There shall be a designated restricted area 4ith a
dedicated observation bay manned by a 9uali6ed*
trained and e/)erienced sta: -or the )ur)ose o-
monitoring o- )atients
The area shall be ade9uately lit and ventilated
Physical restraint
Indications -or )hysical means o- restraint
A restraint is -or the )ur)ose o- the medical
treatment o- the )atient
To )revent the )atient -rom causing in>ury to himsel-
or any other )erson To )revent the )atient -rom )ersistently destroying
)ro)erty
@hen other less restrictive method o- treatment to
calm the )atient has not been success-ul
E9ui)ment )rohibited to be used as )hysical means o-
restraint
Strings* ro)es and raKaW
Handcu:s* shac8les
+ody restraintW
Strait >ac8etW
Chains =-rom 4hatever material?W
@ireW
+andageW
E9ui)ment 4ith tears* )rotruding metal )arts or any
de-ect that may endanger )atient
E9ui)ment that may be used as )hysical means o- restraint
Restraint bedW
Restraint chairW
Padded restraints made o- either calico cloth orcotton * leather * nylon* vinyl * )olyurethane* silicone
or rubber based materialsW and
Any other e9ui)ment a))roved by the "irector
eneral
A))lication o- )hysical means o- restraint
carried out or su)ervised by 9uali6ed* trained and
e/)erienced )ersonnel
a))lied only to the limbs o- a )atient It shall not be necessary to obtain a )ersonLs
consent to the a))lication o- )hysical means o-
restraint
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No )hysical restraint is allo4ed in the )sychiatric
nursing home and community mental health centre*
EVCEPT at the time o- Trans)ortation o- )atients to a
)sychiatric hos)ital
I- the )atient is acutely disturbed* a member o- the
nursing sta: shall visit at intervals o- not more than
6-teen minutes A medical oKcer or registered medical )ractitioner
shall e/amine the acutely disturbed )atient at
intervals o- not more than -our hours
Removal o- )hysical means o- restraint
"ecision to remove the restraints shall be made by
the )sychiatric nurse on.duty
The medical oKcer or registered medical )ractitioner
must be in-ormed o- the termination o-
restraints
Chemical restraint
A))lication o- chemical means o- restraint
Consent -or chemical means o- restraint consent
shall be obtained -rom a voluntary )atient )rior to
chemical means o- restraint
I- the )atient is acutely disturbed* a member o- the
nursing sta: shall visit at #! minutes interval
A medical oKcer or registered medical
)ractitioner shall e/amine the acutelydisturbed )atient at intervals o- not more than $
hours
Seclusion
Indications -or seclusion
A )atient in a )sychiatric hos)ital may be 8e)t in
seclusion only i- it is necessary -or the )rotection*
sa-ety or 4ell.being o- the )atient or other )ersons
4ith 4hom the )atient 4ould other4ise be in
contact
;ther less restrictive method o- treatment to calmthe )atient has not been success-ul
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A))lication o- seclusion
It is not necessary to obtain a )ersonLs
consent -or his seclusion to him or her
A member o- the nursing sta: shall visit an acutely
disturbed )atient at intervals o- not more than
6-teen minutes
A medical oKcer or registered medical
)ractitioner shall visit the )atient under
seclusion at intervals o- not more than -our hours$
The )atient may re9uest to communicate 4ith others
4hile under the seclusion