psychiatry simplified for medical students (dsm iv-tr)

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    PSYCHIATRY

    Ida

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    Content

    Title Page Number

    Psychiatric Evaluation 2iaison Psychiatry !

    Personality "isorders #$

    Stress "isorders #%

    Childhood "isorders #&

    Eating "isorders 2'

    Substance Abuse 2%

    Schi(o)hrenia* "e)ression and +i)olar ,ood "isorder '%

    Suicide and "eliberate Sel-.harm $2

    An/iety "isorders $!

    Pregnancy.related "e)ression $0

    Cognitive "isorders !1

    Psychotro)ic treatment !0

    EPS and N,S %

    ,alaysian Psychiatry %0

    Note: This book follows the diagnostic criteria from DSM-IV-TR

    #

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    Psychiatric evaluation

    3no4ing the )atient

    Predis)osing -actor 4hy did the )atient develo) this disorder5

    signi6cant -amily history

    )ersonality disorder or traits

    traumatic childhood e/)eriences

    chronic stress

    substance use

    Preci)itating -actor

    4hy develo) at this )oint in time5

    Protective -actor

    4hat are the -actors that 4ill hel) him recover5

    good social su))ort

    good )re.morbid level o- -unctioning

    good insight

    early intervention

    no substance use including alcohol no criminal behaviour

    Per)etuating -actor

    4hat are the -actors that may )revent him -rom

    getting better5

    )oor social su))ort

    )oor )re.morbid level o- -unctioning )oor insight

    late treatment

    co.morbid substance use

    criminal record

    unem)loyment

    ,ental State E/amination

    A))earance and behaviour

    Abnormal behaviour

    +uilt

    Cleanliness* consciousness* coo)eration

    "istractibility* dressing

    Eye contact

    7acial e/)ressions

    S)eech

    anguage s)o8en Ade9uate

    Coherent

    Relevant

    Com)rehension o- s)eech

    2

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    ,ood and A:ect

    Current mood

    abile mood

    Congruent a:ect

    Thought content

    "elusions

    ;bsessions

    Concerns

    Suicidal thoughts

    "e)ressive thoughts

    Phobias

    Perce)tion

    Hallucinations

    Illusions

    Cognitive -unctions

    orientation to time* )lace and )erson

    memory< immediate =immediate recall o- ! ob>ects?*

    recent =recall the ! ob>ects a-ter ! minutes* eventsthat ha))ened last 2$ hours?* remote =IC number*

    address?

    Attention and concentration< serial * @;R"

    bac84ards

    Abstract reasoning and concrete thin8ing< e/)lain a

    )roverb* similarities bet4een table and chair

    eneral 8no4ledge< ca)ital city o- ,alaysia*

    Inde)endence "ay

    Budgment< in a burning house* burglar in the house

    Insight< a4areness* attribution and acce)tance o-condition

    Physical e/amination

    . to rule out medical causes -or the sym)toms

    . to chec8 -or side e:ects -rom )sychiatric medications

    . to loo8 -or co.morbid medical disorders

    ,ultia/ial diagnosis

    A/is I< Psychiatric disorder

    A/is II< "evelo)mental or )ersonality disorder

    A/is III< eneral ,edical condition

    A/is I< Presence o- ongoing )sychosocial stressors

    A/is < lobal Assessment o- 7unctioning

    '

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    iaison )sychiatry

    Classi6cation o- )sychiatric illness encountered in

    liaison setting

    . Psychiatry )rovo8ing ill.health

    . Psychiatry as conse9uence o- organic disease

    . )sychiatric sym)toms as )resenting sym)toms

    . cerebral com)lications o- organic disease

    . abuse o- alcohol and drugs

    . deliberate sel-.harm

    . se/ualDrelationshi) )roblems and eating disorders

    . )sychiatric disorder e/acerbate )hysical illness

    . )hysical sym)toms 4ithout organic basis

    . )sychiatric and )hysical illness occurring by chance

    iaison case summaries

    . reason -or re-erral

    . )sychiatric diagnosis

    . )hysical disease and )atients reaction to it

    . evidence o- abnormal illness behaviour

    . relationshi) bet4een the )sychological and )hysical

    as)ects o- the case

    $

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    . )atients )ersonality co)ing strategies

    . )atients attitude to4ards )sychiatric intervention

    . sta: attitude to4ards )atient

    Psychiatric disorder in )hysical illness

    7actors a:ecting )revalence o- )sychiatric disorder in

    )hysical illness

    Illness

    sym)toms

    threat to li-e

    course =acute* rela)sing* chronic?

    duration

    disability

    cons)icuousness

    Treatment

    nature

    side.e:ects

    uncertainty o- outcome

    need -or sel-.care

    Patient

    )sychological vulnerability

    social circumstances

    other stresses =chronic and acute?

    reactions o- others

    7actors associated 4ith a )articularly high ris8 o-

    )sychiatric )roblems

    Severe illness

    un)leasant

    threatening

    acute rela)sing or )rogressive illness

    Fn)leasant treatment

    ma>or surgery

    radiothera)y

    chemothera)y

    ulnerable )atients

    history o- )revious )sychiatric )roblems

    current )sychiatric disorder

    adverse social circumstances lac8 o- )ersonal and emotional su))ort

    Im)lications -or assessment

    Characteristics o- Gat.ris8G )atients

    !

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    systematic revie4 o- )atients* loo8ing -or )sychiatric

    )roblems

    )resence o- 8ey sym)toms

    in-ormation -rom relatives

    im)lications -or treatment

    A:ective disorder

    . 4orsens )rognosis o- stro8e and ,I

    Positive )sychological changes

    . enhanced a))reciation o- li-e

    . less concern -or trivial or material things

    . more tolerance to4ards others

    . im)roved sel-.4orth

    Sic8 role

    . sic8 individual is obliged to see8 the a))ro)riate hel)*

    coo)erate 4ith assessment* acce)t a diagnosis and com)ly

    4ith the treatment

    . legitimate ado)tion o- this role re9uires sanction -rom

    relatives* medical )ractitioners* em)loyers and others in

    authority

    Illness behaviour

    . describes the actions o- the )atient and his attitude

    to4ards medical )ersonnel

    . eg stoical* restrained* histrionic* dramati(ing* hostile*

    sus)icious* irtatious* )leading* aloo-* e/cessively

    coo)erative and agreeable

    Abnormal illness behaviour

    . uncom-ortable a4areness o- bodily events much o- the

    time together 4ith e/cessive -ears and concerns about

    health and disease

    . relentless search -or causes and cures cou)led 4ith

    inability to acce)t reassurance -rom doctors even 4hen this

    has been given clearly )lus a))ro)riate investigation done

    . inability to acce)t the suggestion that non.)hysical

    -actors may be relevant to ones condition

    . disability out o- )ro)ortion to detectable organic disease

    . rein-orcement o- illness behaviour by -amily* disability

    )ayments and health care )roviders

    . ina))ro)riate res)onse to )hysical disorder . either

    e/cessive disability or denial o- need o-

    treatmentDlimitation o- activities

    . ado)tion o- li-estyle around the sic8 role 4ith re)ertoire o-behaviours to sustain sic8 role

    %

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    "e)ression

    Ris8 -actors -or de)ressive disorders in )hysical illness

    . -emale gender

    . being unmarried

    . living alone

    . )revious de)ressive e)isodes

    . certain medical treatments

    . severe -orms o- )hysical illness

    "e)ression in )hysically ill

    . co.morbid disorders continue a-ter discharge

    . o-ten goes undetected

    . de)ressive disorders co.occurring 4ith )hysical illness

    com)licate treatment o- both disorders

    . )redicts readmission

    . )ost)oning treatment o- de)ressive disorder 4orsens

    )rognosis o- both

    . high healthcare costs

    . )oor 9uality o- li-e

    Possible mechanism o- co.morbidity

    . e:ect on neurotransmitters

    . e:ect on immune system

    . side e:ects o- medications

    . )hysical se9uelae o- suicide attem)ts

    . )ossible common genetic )redis)osition

    Post.stro8e de)ression

    . u) to !1 o- )atients develo) )ost.stro8e de)ression in

    acute )ost.stro8e )eriod

    Ris8 -actors -or )ost.stro8e de)ression

    . le-t anterior brain lesions =es)ecially caudate nucleus?

    . dys)hasia

    . living alone

    . )ast history o- ma>or de)ressive e)isodes

    . )revious history o- )yschiatric andDor cerebrovascular

    disorder

    . -amily history o- mood disorders

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    An/iety

    . causes increased vulnerability to cardiac events

    . )hobic an/iety and generalised an/iety are )redictors o-

    ,I and cardiac death

    Antici)atory an/iety

    . )er)etuates the disability

    ;rganic an/iety syndromes

    . cardiovascular system< angina* arrhythmia* congestive

    cardiac -ailure

    . endocrine system< hy)erthyroidism* )haeochromocytoma*meno)ause

    . metabolic disorders< hy)oglycemia* hy)o/ia

    . neurologic disorders< sei(ure disorder* a8athisia

    . gastrointestinal system< )e)tic ulcer disease

    . res)iratory system< asthma* C;P"

    . immunologic disorder< ana)hyla/is* SE

    ,edications that cause an/iety.li8e sym)toms

    Stimulant into/ication< ca:eine* nicotine* cocaine*

    metam)hetamines* )hencyclidine

    Sym)athomimetics< )seudoe)hedrine*

    methyl)henidate* am)hetamines* beta agonists

    "o)aminergics< amantadine* bromocri)tine*

    levodo)a

    Anticholinergics< ben(tro)ine* di)henhydramine*

    me)eridine

    ,iscellaneous< e)hedrine* indomethacine*

    steroids

    "rug 4ithdra4al< alcohol* +"J* o)iates

    Cancer

    . )sychological im)act o- diagnosis de)ends on the 4ay the

    disease )resents

    . im)act is greater i- cancer is detected une/)ectedly in an

    a))arently healthy )erson

    . uncertainty 4hen )atient 6rst comes to clinic may be so

    stress-ul that they develo) an/iety 4hile 4aiting -or the

    investigation results

    &

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    ,eaning o- cancer to the )atient. loss o- )hysical strength and 4ell being

    . loss o- inde)endence

    . loss o- role

    . loss o- )ersonal relationshi)s

    . loss o- li-e e/)ectancy

    . loss o- control . the younger )atient* the greater the

    im)act

    "evelo)ment o- emotional )roblems

    . no )sychiatric disorder< !1

    . ad>ustment reaction< '1

    . -ormal )sychiatric diagnosis< 21

    7actors contributing to )sychological )roblems. concern about )rognosis and 4el-are o- relatives

    . )oorly controlled )hysical sym)toms eg )ain* nausea*

    breathlessness

    . vulnerable )ersonality . )oor co)ing 4ith stress

    . direct e:ects o- illness to the brain

    . side e:ects o- drugs

    . metabolic disturbances such as liver -ailure

    . -ear o- being abandoned as the disease )rogresses

    . lac8 o- con6ding relationshi)s

    . other li-e events or diKculties not related to cancer

    Prevention o- emotional )roblems

    . o:er in-ormation about illness and its treatment . may be

    re)eated later

    . allo4 the )atient to e/)ress emotional distress

    . )rovide ongoing care

    "etection o- emotional )roblems

    . sim)le screening 9uestionnaire re)eated at regular

    intervals

    . as8 )atient -rom time to time ho4 they have been co)ing

    4ith the emotional side o- illness and let them discuss theircurrent concerns

    0

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    An/iety

    . may be mi/ed 4ith de)ression

    . around time o- initial diagnosis and 4hile 4aiting -or

    results -or sus)ected rela)se

    Ris8 -actors -or an/iety

    . harbouring underground -ears about illness or its

    treatment and too -rightened to share 4ith the sta:

    . see8s out more in-ormation than they can handle

    . inaccurate in-ormation -rom non.medical )ro-essionals

    . )ersonality

    E:ect o- an/iety on cancer treatment

    . chronically an/ious )atients 4ould consult doctors

    -re9uently and become hy)ochondriacal once the diagnosis

    is con6rmed

    . -alse alarms about s)read o- disease

    . very concerned about treatment and its side e:ects

    . avoidance o- treatment

    . may 8ee) their sym)toms a secret* resulting in a delayed

    diagnosis

    . inter-ere 4ith treatment and diagnostic test

    "enial

    . unconscious re-usal to ac8no4ledge certain distressing

    as)ects o- reality

    . to )rotect themselves -rom an/iety and un)leasantness in

    daily li-e

    . usually lasts not more than a -e4 days

    Sus)ect denial 4hen

    . reactions

    . loo8s -or another )hysician in the ho)e o- getting aGbetter e/)lanationG

    . as8s -or re)eated investigations* )artially 8no4ing that

    the original diagnosis is correct

    . -ail to reali(e their diagnosisD)rognosis

    . -ails to as8 9uestions about the illness

    . -orgets the in-ormation given

    . ma8ing unrealistic )lans -or the -uture

    . understands the matters in intellectual sense 4ithout

    a))ro)riate emotional distress

    Ada)tive denial

    #1

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    . denial acts as a bu:er a-ter une/)ected ne4s* allo4ing

    )atient to collect himsel- and mobili(e other resources

    . denial is a tem)orary de-ense and 4ill be re)laced by

    )artial acce)tance

    . it enables )atients to ac8no4ledge their cancer andacce)t necessary treatment at one level o- conscious

    a4areness

    . at another level they )lay do4n the seriousness o- the

    illness

    . they may tal8 briey about the reality o- their situation

    be-ore indicating their inability to loo8 at it realistically any

    longer =daydream* -antasies* tal8ing about brighter things

    4hich contradict 4hat he said earlier?

    ,alada)tive denial

    . delays cancer diagnosis

    . )oor com)liance

    . bloc8ed communication 4ith relatives

    ,anagement o- denial

    . Collusion

    going along 4ith the )atients vie4

    8ind to the )atients but the sta: -eels uncom-ortable

    . Con-rontation

    challenging the )atient 4ith the truth

    sta: -eels better but causes great distress to the

    )atient

    . ,iddle a))roach

    am)le o))ortunity -or )atient to as8 9uestions but

    never -orcing un4anted in-ormation u)on them

    Anger

    . transient anger is a normal )hase in the ad>ustment

    )rocess

    . some )atients may obtain relie- through the s)ontaneous

    -ree e/)ression o- anger be-ore they move on to4ards

    acce)tance

    . -amily and nurses 6nd it hard to co)e because anger is

    dis)laced at all directions and )ro>ected at random

    . anger can be more mar8ed in the relatives

    . sta: or -amily member should not react )ersonally

    because it -eeds into the )atients hostile behaviour

    ##

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    Ty)es o- anger

    . -ree oating< angry about the un-airness o- the illness*

    blaming -ate or od

    . dis)laced< to4ards healthcare sta:

    . >usti6ed< delay in ma8ing diagnosis

    . su))ressed< not co.o)erative and leads to de)ression

    @hy anger5

    . com)aring sel- 4ith others . limited activity

    . as8ing -or attention to ma8e sure that he is not -orgotten

    . loss o- control

    ,anagement o- anger

    . listen to )atient* donLt be de-ensive and donLt ma8e

    >udgments

    . o:er consistent )ro-essional care although the )atient is

    ungrate-ul

    . -acilitate a -ull blo4n e/)ression o- anger by a neutral

    counsellor

    . res)onding to criticisms o- other doctors and nurses

    . colluding 4ith the blame on colleagues is un4ise and

    un-air

    . encourage redirection o- anger and re.chanelling the

    energy else4here eg e/ercise* music* creative activity and

    cancer.related charity 4or8

    . medication< )sychotro)ics

    "e)ression in cancer

    . usually associated 4ith a great sense o- loss

    . 6nancial burden

    . loss o- >ob due to -re9uent absences or inability to

    -unction

    . drugs< cytoto/ics* steroids

    Clinical )resentation

    . )hysical sym)toms seem to be out o- )ro)ortion to thestage o- cancer )rogression eg 4eight loss* anore/ia*

    -atigue

    . insomnia es)ecially morning a4a8ening

    . an/iety

    #2

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    . diKcult to control )ain

    . suicidal thoughts

    Ty)es o- de)ression

    . reactive de)ression

    encouragements and reassurances

    . )re)aratory grie-

    ta8es into account im)ending losses

    allo4 )atient to e/)ress their sorro4

    E:ect on cancer treatment. )atient may consider themselves too 4orthless to get

    hel)

    . they do not com)lain

    . )oor 9uality o- li-e

    ,anagement o- de)ression

    . let )atient e/)ress their -eelings o- sadness and anger

    . -oster a 6ghting s)irit* but i- )atient is very de)ressed* it

    can accentuate the sense o- shame and -ailure

    . i- de)ression )ersists a-ter sim)le discussion* more

    s)ecialised treatment such as )sychothera)y and

    antide)ressants 4ill be re9uired

    Acce)tance. a stage 4here the )atient is neither de)ressed nor angry

    about his -ate

    . almost void o- -eelings

    . as i- the struggle is over

    . )atient )re-ers to be le-t alone

    . not in a tal8ative mood

    . communications become more non.verbal than verbal

    #'

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    Personality "isorders

    CFSTER A< ;dd

    Paranoid

    . Sus)icious* sensitive* mistrust-ul* resent-ul* sel-.im)ortant

    Schi(oid

    . Cold* detached* lac8 en>oyment* intros)ective

    Schi(oty)al

    . socially an/ious* cognitive and )erce)tual distortions*

    oddities o- s)eech* ina))ro)riate a:ective res)onse*

    eccentric behaviour

    CFSTER +< "ramatic

    Antisocial

    . ac8 o- concern -or others -eelings* transient

    relationshi)s* irres)onsible* im)ulsive and irritable* lac8

    guilt and remorse* -ail to learn -rom adverse e/)erience

    Social learning in childhood -or antisocial behavior

    . through gro4ing u) in an antisocial -amily

    . through lac8 o- consistent rules in the -amily

    . learnt as a 4ay o- overcoming another )roblem

    . -rom )oor ability to sustain attention and other

    im)ediments to learning

    +orderline

    . Identity disturbance* intense unstable relationshi)s*

    e:orts to avoid abandonment* recurrent suicidal behavior*transient stress.related )aranoid ideation* im)ulsive*

    diKculty controlling anger* unstable a:ect* history o-

    conduct disorder be-ore #!

    Histrionic

    . Sel-.dramati(ation* suggestible* shallo4 and labile a:ect*

    see8s attention and e/citement* ina))ro)riately seductive*

    over.concerned 4ith )hysical attractiveness* e/cessively

    im)ressionistic s)eech* considers relationshi)s moreintimate than they are

    Narcissistic

    #$

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    . randiose sel-.im)ortant* e/)loits others* re9uires

    e/cessive admiration* envious and e/)ects to be envied*

    lac8s em)athy

    CFSTER C< An/ious

    Avoidant

    . -eels socially in-erior* )reoccu)ied 4ith )ossibility o-

    re>ection* avoids involvement 4ith ne4 e/)eriences and

    )eo)le* avoid ris8* avoid social activity* restraint in intimate

    relationshi) -rom -ear o- being shamed or ridiculed*

    inhibited in ne4 )ersonal situations due to -eelings o-

    inade9uacy

    "e)endent

    . Allo4s others to ta8e res)onsibility* unduly com)liant 4ith

    4ishes o- others* -eels unable to care -or themselves* -ear

    o- being le-t to care -or themselves* diKculty initiating

    )ro>ects* goes to e/cessive lengths to obtain su))ort*

    urgently see8s a su))ortive relationshi)

    ;bsessive.com)ulsive

    . Preoccu)ied 4ith detailsDrules* inhibited by )er-ectionism*

    over.conscientious* e/cessively concerned 4ith

    )roductivity* rigid and controlling* miserly* cannot discard

    4orthless or 4orn.out ob>ects

    ;THERS

    Passive.aggressive

    . Passive resistance 4hen given demands -or ade9uate

    )er-ormance

    "e)ressive

    . Persistently gloomy* strong sense o- duty* little ca)acity

    -or en>oyment* unsatis6ed 4ith their li-e

    Hy)erthymic

    . Habitually cheer-ul and o)timistic* )oor >udgement* >um)s

    to conclusion* )eriods o- irritability

    Cycloid

    . E/tremes o- de)ressive and hy)erthymic )ersonality

    disorders

    #!

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    Stress "isorders

    Acute stress reaction

    . 7ree(e* 6ght* ight

    . Avoidance and denial should recede as an/iety diminishes

    to allo4 coming to terms 4ith the stress-ul e/)erience

    Acute stress disorder

    . onset 4hile or a-ter e/)eriencing the distressing event

    . asts M2 days but $ 4ee8s

    . co)ing strategy< avoidance o- reminders* use o- alcohol or

    drugs

    . de-ence mechanisms< denial* dis)lacement* regression

    "iagnosis

    . stressor

    e/)osure to event involving actualDthreatened

    deathDserious in>ury to sel- or others e/)erience o- -earDhel)lessnessDhorror or

    disorgani(edDagitated behaviour in children

    . sym)toms

    re.e/)eriencing o- the event

    avoidance o- stimuli that arouse recollections o- the

    trauma

    mar8ed sym)toms o- an/iety or hy)erarousal

    signi6cant distress or im)aired social -unctioning

    M' o-< sense o- numbingDdetachment* reduced

    a4areness o- surroundings* dereali(ation*

    de)ersonali(ation* dissociative amnesia

    ,anagement

    . assess by acute stress disorder intervie4* acute stress

    disorder scale. Critical incident stress debrie6ng< -acts* thoughts*

    -eelings* assessment* education

    .reassurance that the condition is -re9uent and short.lived

    .short.term an/iolytic =i- an/iety is severe? and hy)notic =i-

    severely disru)ted slee)?

    .7ollo4.u) 4ithin # month

    . )revention< cognitive behavioural intervention 2.4ee8s

    )ost.trauma* )re)are individuals at ris8 =eg E,S andmilitary? by training to remain calm and ob>ective* avoid

    identi-ying 4ith victims* e/)ress emotional reactions

    #%

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    PTS"

    . traumatic event< e/)erienced* 4itnessed or con-ronted

    4ith an event that involved actual or threatened death or

    serious in>ury or a threat to the )hysical integrity o- sel- orothers

    . etiology< -ear conditioning* hy)othalamic.)ituitary.adrenal

    a/is abnormalities* or adrenergic e:ect on amygdala

    . )re.dis)osing -actors< 4omen* -amily history o- )sychiatric

    disorder* )ersonal history o- mood and an/iety disorder*

    )revious history o- trauma* lo4er intelligence* lac8 o- social

    su))ort

    . signi6cant distress or im)aired social -unctioning -or M#

    month

    . re.e/)erience by M# o-

    ashbac8s

    dreams

    trauma re.enactment

    distress or reactivity to cues resembling an as)ect o-

    the event

    . avoidance o- reminders by M' o-

    thoughts

    activities

    inability to recall

    reduced interest

    numbness

    restricted a:ect

    sense o- -oreshortened -uture

    . hy)erarousal by M2 o-

    insomnia

    irritability

    )oor concentration

    hy)ervigilance

    e/aggerated startle res)onse

    . assess by clinician.administered PTS" scale =gold

    standard? or )ost.traumatic stress diagnostic scale

    . management< counselling* C+T* i- )atient )re-ers or i-

    )sychothera)y unavailable then give SSRI or TCA and

    continue -or a year i- good res)onse

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    Childhood disorders

    Attention.de6citDhy)eractivity disorder

    . )attern o- diminished sustained attention and higher

    levels o- im)ulsivity in a child or adolescent than e/)ected

    -or someone o- that age and develo)mental level

    . more )revalent in boys

    . attention.de6cit disorder< )ersistent -or at least % months

    o- M % sym)toms o-

    -ailing to give close attention to details or ma8es

    careless mista8es in activities*

    o-ten has diKculty sustaining attention in tas8s or

    )lay activities*

    o-ten does not seem to listen 4hen s)o8en to

    directly*

    o-ten does not -ollo4 through on instructions and

    -ails to 6nish chores*

    o-ten has diKculty organi(ing tas8s*

    o-ten avoidsDdisli8esDreluctant to engage in tas8s

    that re9uire sustained mental e:ort*

    o-ten loses things necessary -or tas8s*

    o-ten easily distracted by e/traneous stimuli* o-ten

    -orget-ul in daily activities

    . hy)eractivity disorder< )ersistent o- at least % months o-

    M % sym)toms o-

    o-ten 6dgets 4ith handsD-eet or s9uirms in seat* o-ten leaves seat in situations in 4hich remaining

    seated is e/)ected*

    o-ten runs about or climbs e/cessively in situations

    in 4hich it is ina))ro)riate*

    o-ten has diKculty )laying or engaging in leisure

    activities 9uietly*

    o-ten Gon the goG or acts as i- Gdriven by a motorG*

    o-ten tal8s e/cessively

    . some sym)toms that caused im)airment 4ere )resent

    be-ore years old

    . cognitive testing including a continuous )er-ormance tas8

    =the child is as8ed to )ress a button each time a )articular

    se9uence o- letters or numbers ashes on the screen?

    . 6rst.line management< CNS stimulants methyl)henidate

    and de/troam)hetamine

    . second.line management

    nore)ine)hrine u)ta8e inhibitor Atomo/etine*

    antide)ressant venla-a/ine*

    al)ha.adrenergic rece)tor agonist clonidine

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    Autism

    . 9ualitative im)airment in social interaction* im)airment in

    communication* restricted re)etitive and stereoty)ed

    )atterns o- behaviourDinterests

    . due to neuroanatomical or biochemical -actors

    . onset ' years o- age o- delays or abnormal -unctioning

    in M # area =social interaction* language used in social

    communication* symbolic or imaginative )lay?

    . total o- M % items 4ith

    M2 -rom 9ualitative im)airment in social interaction

    lac8 o- eye contact* -acial e/)ression and gestures*

    no -riends*

    lac8 o- social and emotional reci)rocity

    M # -rom 9ualitative im)airments in communication

    delay or lac8 o- develo)ment o- s)o8en language*

    diKcult to initiate and sustain a conversation* stereoty)e and re)etitive use o- language or

    idiosyncratic language

    M# o- restricted* re)etitive and stereoty)ed )atterns o-

    behaviourDinterestDactivities

    adherence to s)eci6c routines or rituals*

    stereoty)ed and re)etitive motor mannerisms

    . more -re9uent in boys

    . associated 4ith congenital rubella* )henyl8etonuria*

    tuberous sclerosis

    . may be due to immunological incom)atibility 4ith mother

    =maternal antibodies directed at -etus? or )erinatal

    com)lications

    . management< target behaviours that 4ill im)rove their

    abilities to integrate into schools* develo) meaning-ul )eer

    relationshi)s and increase the li8elihood o- maintaininginde)endent living as adults

    Retts syndrome

    . )rogressive condition o- develo)mental deterioration 4ith

    onset a-ter several months o- a))arently normal

    develo)ment

    . a))arently normal )renatal and )erinatal develo)ment

    . a))arently normal )sychomotor develo)ment through the

    6rst ! months a-ter birth

    . normal head circum-erence at birth

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    . onset o- all o- the -ollo4ing a-ter the )eriod o- normal

    develo)mentor de)ressive e)isode M# 4ee8

    Ra)id cycler< M$ mood s4ings in # year

    Treatment -or mania

    sodium val)roate*

    olan(a)ine*

    chlor)roma(ine* halo)eridol*

    9uetia)ine*

    ari)ira(ole*

    ris)eridone*

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    ECT

    Treatment -or de)ression

    SSRI 7luvo/amine

    amotrigine*

    o-e)ramine =A;I" i- suicidal?*

    ECT

    ,aintenance

    lithium*

    carbama(e)ine =es) ra)id.cycling?

    lamotrigine

    High ris8 clinical -actors -or suicide includeor de)ressive disorder but tend toe/)erience more mood uctuation and )rominent an/iety

    sym)toms

    . "isinterest in the ne4born D -ear-ul o- being le-t alone 4ith

    the baby

    . Increased ris8 o- suicide* neglect o- the ne4born and

    in-anticide

    . Treatment includes antide)ressants 7luo/etine =SSRI? or

    "othie)in =TCA?* ECT and )sychothera)y

    . Ris8 o- recurrence is !1

    Post)artum )sychosis

    . ;nset usually 4ithin the 6rst month

    . usually in )rimi)arous or 4hen there is a history o-

    )erinatal com)lications

    . Early stages similar to )ost)artum blues* )rogress to

    -ran8 )sychosis 4ith sus)iciousness* delusions*

    hallucinations 4hich may involve the child

    . may have im)ulses to harm the child

    . agitated* )oor slee)

    . Treatment includes ECT* anti)sychotics 4ith mood

    stabili(ers i- bi)olar in )resentation and anti)sychotics 4ith

    antide)ressants i- de)ressed

    . Advice on non.hormonal contrace)tion

    . Ris8 o- recurrence is 1

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    Cognitive disorders

    "elirium

    . Acute global cognitive im)airment in the setting o-

    clouded consciousness =)atient is a4a8e but has reduced

    a4areness o- environment and is unres)onsive?

    . o-ten reversible and brie-

    Predis)osing -actors

    age M%!*

    male*

    cognitive im)aired =dementia* de)ression?*

    -unction im)airment =-unctional de)endence*

    immobility?*

    sensory im)airment*

    decreased oral inta8e*

    substance use*

    coe/isting medical conditions

    Preci)itating -actors

    drugs =narcotics* )oly)harmacy?*

    )rimary neurological disease*

    intercurrent illness*

    surgery*

    environmental =)hysical restraint* ICF admission*

    multi)le )rocedures?

    Patho)hysiology

    cholinergic de6ciency*

    do)amine =regulates acetylcholine?*

    changes in +++

    "iagnosis

    disturbance o- consciousness 4ith reduced ability to

    -ocus* sustainDshi-t attention*

    change in cognition or develo)ment o- )erce)tual

    disturbance*

    develo)ment o- disturbance over a short )eriod o-

    time =hours to days? and uctuates

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    Ty)es

    "elirium due to a general medical condition

    =evidence -rom history* PE or laboratory 6ndings? egmeningitis* head in>ury* stro8e* FTI* chest in-ection*

    PE* ,I* arrhythmia* he)atic ence)halo)athy*

    hy)erDhy)oglycemia in diabetes* e)ile)sy*

    malignancy

    delirium due to into/ication =sym)toms develo)ed

    during substance into/ication* medication use is

    etiologically related to the disturbance* cognitive

    sym)toms are in e/cess o- into/ication syndrome? eg

    insulin* digo/in* lithium* o)iates* ben(odia(e)ines

    delirium due to substance 4ithdra4al =sym)toms

    develo)ed during or shortly a-ter a 4ithdra4al

    syndrome* cognitive sym)toms in e/cess o-

    4ithdra4al syndrome?*

    delirium due to multi)le etiology*

    delirium not other4ise s)eci6ed

    Investigations

    "elirium Rating Scale evaluates tem)oral onset o-

    sym)toms* uctuation* )erce)tual disturbances andhallucinations*

    Con-usion Assessment ,ethod tool =re9uires acute

    onset and uctuating course 4ith inattention and

    either disorgani(ed thin8ing or altered level o-

    consciousness?

    Abbreviated ,ental Test Score to establish cognitive

    de6cits )resent on admission and -or a baseline

    score -or assessing )rogress

    Non.)harmacological management

    avoid e/tremes o- sensory in)ut*

    relie- o- distress*

    control agitation and )revent e/haustion*

    )sychosocial su))ort

    Pharmacological management

    ensure drug treatment -or underlying )hysical

    )roblem is the minimum re9uired

    anti)sychotics -or agitated )atients 4ith )erce)tual

    disturbances*

    treatment o- s)eci6c etiologies

    "ementia

    . global im)airment o- intellect 4ithout im)aired

    consciousness

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    . cognitive -unctions a:ected include memory* orientation*

    )erce)tion and attention* >udgment* language and )roblem

    solving and abstract thin8ing

    . score o- 2' out o- '1 in ,,SE is suggestive o- cognitive

    im)airment

    . inter-eres 4ith social and occu)ational -unctioning

    . )atients may have e)isodes o- violence or abuse to4ards

    others and sel-.harm in advanced dementia

    . )atients are vulnerable to )hysical* mental and 6nancial

    abuse by others

    Reversible causes o- dementia

    Hy)othyroidism

    it +#2 de6ciency

    Subdural haematoma Fremia

    Normal )ressure hydroce)halus

    Sy)hilis

    Irreversible causes o- dementia

    Al(heimers disease

    ascular dementia

    AI"S

    Ouestions to elicit ty)e o- memory diKculties

    +eing more -orget-ul5

    osing your train o- thought5

    Problems trying to 6nd the right 4ord5

    "iKculty -ollo4ing conversations5

    7orgetting to turn things o: such as the lights or

    stove5

    3ee)ing trac8 o- time5

    ;thers e/)ressing concern about your memory5

    7unction

    $ instrumental activities o- daily living

    . As8 caregiver 4hether )t needs assistance in these areasugate ga(e disorder are ty)ical?

    . Thiamine de6ciency may be secondary to alcoholism*

    vomiting during )regnancy* dietary insuKciency or gastric

    carcinoma

    . Treatment is 4ith urgent intravenous thiamine* but the

    ma>ority 4ill develo) a chronic 3orsa8o: syndrome

    Creut(-eldt.Bacob disease

    . characteri(ed by a ra)idly )rogressive dementia*

    myoclonus and distinctive electroence)halogra)hic and

    neuro)athologic 6ndings

    . The in-ectious agent causing CB" is uni9ue in being a

    con-ormationally abnormal )rion )rotein ie contains no

    genetic material

    . The dementia can be accom)anied by signs o-

    involvement o- any )art o- the central nervous system* but

    myoclonus is )articularly common

    . Although ty)ically occurring s)oradically in middle.aged

    adults* a -amily history may be )resent in &.#1

    . variant CB" in young adults has been lin8ed 4ith

    e/)osure to bee- in-ected 4ith the bovine s)ongi-orm

    ence)halo)athy agent This ne4 variantL -orm o-ten

    )resents 4ith an e/tended neuro)sychiatric )rodrome 4ithmood disturbance or other )sychiatric sym)tomatology

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    Secondary causes o- dementia

    . ,etabolic< thiamine de6ciency* vitamin +#2 de6ciency*

    hy)othyroidism* Cushings syndrome* @ilsons disease

    . ascular< Cerebrovascular disease* subdural haematoma

    . Neo)lastic< )rimary CNS tumours* metastases

    . Inammatory< SE

    . "rugs and to/ins< Anticholinergics* heavy metal e/)osure

    . In-ection< Sy)hilis

    Elderly Cognitive Assessment Ouestionnaire

    . A score o- or more is indicative o- normal memory and a

    score o- $ and belo4 indicate )robable dementia This is

    use-ul -or routine screening

    ,,SE

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    . This is the most 4idely used instrument -or assessing

    severity o- the dementia Ho4ever it can only assess the

    domains o- cognitive de6cit The ma/imum score is '1 The

    lo4er the score* the more severely demented the )atient

    is

    eriatric "e)ression Scale

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    . A short #!.item 9uestionnaire is used to assess the

    de)ression in dementia The )atient has )ossible

    de)ression i- the score is ! or more

    Cloc8 dra4ing test

    . This is used as a measure o- constructional a)ra/ia and

    may also reect -rontal and tem)oro)arietal -unctioning

    lobal "eteroration scale

    . -or staging o- dementia

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    Stage # NormalStage 2 ery mild

    ,emory )roblem re)orted but not evident in

    clinical intervie4Stage ' ,ild im)airment in memory* concentration

    and occu)ational )er-ormance

    Stage $ ,oderate im)airment in memory* 8no4ledgeretrieval and com)lete tas8s

    Stage ! ,od to severe im)airment in recent and

    remote memory* -re9uent disorientation to

    time and )lace* im)airments o- A"Stage % Severe cognitive im)airment 4ith inability to

    tend to A" 4ithout assistanceStage ery severe im)airment in cognition*

    language and motor s8ills

    ,anagement o- dementia

    Eliminate non.essential drugs that could inter-ere

    4ith cognition

    ,onitor driving ability and sa-ety in use o- household

    a))liances

    Re-er to local A" Association -or in-ormation and

    su))ort grou)s

    eneral treatmento su))ortive medical careo emotional su))ort -or )atient and -amily

    o Provide an environment that )rovides -re9uentcues -or orientation

    o Su))ortive thera)y U grou) thera)y

    Sym)tomatic treatment

    o nutritious diet* )ro)er e/ercise* attention to

    visual and auditory )roblems

    Pharmacological treatment -or s)eci6c sym)toms

    Psychotro)ic treatment

    Psychoeducation

    . )sychothera)eutic intervention

    . educate the )atient and their -amilies about the illness*

    the cause and course o- the illness and the role o-

    medication

    . hel)s im)rove )atients insight* com)liance* lo4er rate o-

    rela)se and better sym)tom control

    . enhances su))ort -rom -amily members

    Cognitive +ehavioural Thera)y

    . a 4ay o- tal8ing about ho4 you thin8 about yoursel-* the

    4orld and other )eo)le and ho4 4hat you do a:ects your

    thoughts and -eelings. hel)s to change ho4 you thin8 =Cognitive? and 4hat you

    do =+ehaviour?

    . -ocuses on the here and no4 )roblems and diKculties

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    . Instead o- -ocusing on the causes o- your distress or

    sym)toms in the )ast* it loo8s -or 4ays to im)rove your

    state o- mind no4

    . re9uires commitment and coo)eration -rom the )atient

    . )rovides the )atient 4ith s8ills to a))roach -uture

    )roblems

    . ma8e sense o- over4helming )roblems by brea8ing them

    do4n into smaller )artsected to )hysical means o- restraint or seclusion

    in )sychiatric hos)itals

    The )rivacy and sa-ety o- a )atient shall be observed

    at all times during the restraint or seclusion

    )rocedures

    No )hysical or chemical means o- restraint or

    seclusion shall be a))lied to )atients in any)sychiatric nursing home or community mental

    health centre* e/ce)t during an emergency and the

    )atient shall then be trans-erred to )sychiatric

    hos)itals 4ithout delay

    I- the )eriod o- )hysical means o- restraint o- a

    )atient e/ceeds eight hours* a )sychiatrist shall

    revie4 the )atient on the need -or -urther restraint

    No seclusion shall be carried out on a )atient -or

    more than eight hours consecutively or -or more

    than t4elve hours intermittently over a )eriod o-

    -orty eight hours* 4ithout an inde)endent revie4 bya )sychiatrist

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    Restraint area

    There shall be a designated restricted area 4ith a

    dedicated observation bay manned by a 9uali6ed*

    trained and e/)erienced sta: -or the )ur)ose o-

    monitoring o- )atients

    The area shall be ade9uately lit and ventilated

    Physical restraint

    Indications -or )hysical means o- restraint

    A restraint is -or the )ur)ose o- the medical

    treatment o- the )atient

    To )revent the )atient -rom causing in>ury to himsel-

    or any other )erson To )revent the )atient -rom )ersistently destroying

    )ro)erty

    @hen other less restrictive method o- treatment to

    calm the )atient has not been success-ul

    E9ui)ment )rohibited to be used as )hysical means o-

    restraint

    Strings* ro)es and raKaW

    Handcu:s* shac8les

    +ody restraintW

    Strait >ac8etW

    Chains =-rom 4hatever material?W

    @ireW

    +andageW

    E9ui)ment 4ith tears* )rotruding metal )arts or any

    de-ect that may endanger )atient

    E9ui)ment that may be used as )hysical means o- restraint

    Restraint bedW

    Restraint chairW

    Padded restraints made o- either calico cloth orcotton * leather * nylon* vinyl * )olyurethane* silicone

    or rubber based materialsW and

    Any other e9ui)ment a))roved by the "irector

    eneral

    A))lication o- )hysical means o- restraint

    carried out or su)ervised by 9uali6ed* trained and

    e/)erienced )ersonnel

    a))lied only to the limbs o- a )atient It shall not be necessary to obtain a )ersonLs

    consent to the a))lication o- )hysical means o-

    restraint

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    No )hysical restraint is allo4ed in the )sychiatric

    nursing home and community mental health centre*

    EVCEPT at the time o- Trans)ortation o- )atients to a

    )sychiatric hos)ital

    I- the )atient is acutely disturbed* a member o- the

    nursing sta: shall visit at intervals o- not more than

    6-teen minutes A medical oKcer or registered medical )ractitioner

    shall e/amine the acutely disturbed )atient at

    intervals o- not more than -our hours

    Removal o- )hysical means o- restraint

    "ecision to remove the restraints shall be made by

    the )sychiatric nurse on.duty

    The medical oKcer or registered medical )ractitioner

    must be in-ormed o- the termination o-

    restraints

    Chemical restraint

    A))lication o- chemical means o- restraint

    Consent -or chemical means o- restraint consent

    shall be obtained -rom a voluntary )atient )rior to

    chemical means o- restraint

    I- the )atient is acutely disturbed* a member o- the

    nursing sta: shall visit at #! minutes interval

    A medical oKcer or registered medical

    )ractitioner shall e/amine the acutelydisturbed )atient at intervals o- not more than $

    hours

    Seclusion

    Indications -or seclusion

    A )atient in a )sychiatric hos)ital may be 8e)t in

    seclusion only i- it is necessary -or the )rotection*

    sa-ety or 4ell.being o- the )atient or other )ersons

    4ith 4hom the )atient 4ould other4ise be in

    contact

    ;ther less restrictive method o- treatment to calmthe )atient has not been success-ul

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    A))lication o- seclusion

    It is not necessary to obtain a )ersonLs

    consent -or his seclusion to him or her

    A member o- the nursing sta: shall visit an acutely

    disturbed )atient at intervals o- not more than

    6-teen minutes

    A medical oKcer or registered medical

    )ractitioner shall visit the )atient under

    seclusion at intervals o- not more than -our hours$

    The )atient may re9uest to communicate 4ith others

    4hile under the seclusion