sanbi glossina comparative genomics workshop:

SANBI Glossina genomics workshop Cape Town 04-08 August 08 1

SANBI Glossina comparative genomics workshop:

SANBI Glossina comparative genomics workshop:

TDR new strategy and vector research operational plan

Yeya T. Touré

WHO-TDR ([email protected])


Outline of the presentationOutline of the presentation

1. TDR new vision and strategy

2. Business Line 5: Innovative vector control interventions: Objectives, activities and operational plan


TDR new vision and strategy


Track record

• Supported >10,000 projects; trained >1,500 PhD scientists

• Five of 10 tropical diseases targeted for global / regional elimination

Mission

• To develop new and improved tools for tropical disease control

• To strengthen the research capability of disease endemic countries (DECs)

TDR was established as a special programme 30 years agoTDR was established as a special programme 30 years ago

Key strengths

• UN’s convening power

• Location in WHO and links to ministries and control

• Partner network and brokering capabilities

• Long-standing DEC relationships

• Governance structure


TDR Vision and StrategyTDR Vision and Strategy

www.who.int/tdr


TDR Vision TDR Vision

To foster:

An effective global research effort on infectious diseases of poverty in which disease endemic countries play a pivotal role


Strategic objectivesStrategic objectives

InnovationInterventions

Access


Stewardship / Priority Setting


Empowerment through:Training, Institutional Support and Networks

Rese

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Business Line 5: objectives, activities and operational plan


BL 5 strategic objectivesBL 5 strategic objectives

Overall objective: To develop and evaluate improved and innovative vector control methods for the prevention of neglected diseases.

Specific objectives: • To promote the development and testing of new methods for

improving Human African Trypanosomiasis (HAT) vector control and support the generation and exploitation of Glossina genome sequence data

• To advance the development and evaluation of new and improved integrated methods for malaria and dengue vector control

• To progress the development and evaluation of alternative methods for the prevention of re-infestation and the control of Chagas disease vectors


Development and evaluation of

improved vector control methods

Building capacity in biosafety, exploitation

of vector genome data, training within

funded grants

Facilitating the Glossina genome

sequencing initiative


Consultation meeting defined BL 5 activities and operational frameworkConsultation meeting defined BL 5

activities and operational framework• HAT (Human African Trypanosomiasis): - Improving bait technology, odour release systems

and trapping materials for the enhancement of effectiveness of tsetse fly trapping

- Improving the efficacy of HAT vector control programs through evidence-based planning and implementation of control strategies

• Genetic modification of malaria and dengue vectors: - Addressing the requirements for deployment of genetic control methods

• Malaria: - Developing and evaluating tailored methods for

integrated malaria vector control - Characterizing malaria vector resistance to

insecticides• Dengue: - Improving methods for targeted and integrated

dengue vector control approaches• Chagas disease: - Developing improved methods for the prevention of

re-infestation by triatomine bugs - Developing new methods for control of Chagas

disease vectors

Consultation on a framework for transition from current activities and implementation of the new vector research strategyGeneva, 23-24 April 2007


Objective 1: HAT vector control: Activities, end-products and milestones

sanbi glossina comparative genomics workshop:

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