SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-78 -22 1978-84 13 1984-89 -14 1989-00 00 2000-08 15 2008-17 04 04 04

White 1975-79 -19 1979-84 17 1984-87 -25 1987-99 -02 1999-06 17 2006-17 07 07 07

Black 1975-17 -01 -01 -01

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-17 08 08 08

White 2000-08 13 2008-17 07 07 07

White NHef 2000-08 14 2008-17 08 08 08

Black 2000-17 04 04 04

Black NHef 2000-17 04 04 04

APIe 2000-17 07 07 07

AIANeg 2000-17 02 02 02

Hispanicf 2000-17 06 06 06

US Cancer Mortalityc 1975-2017

All Races 1975-98 -01 1998-17 03 03 03

White 1975-96 -02 1996-17 04 04 04

Black 1975-87 14 1987-17 -05 -05 -05

US Cancer Mortalityc 2000-2017

All Races 2000-17 03 03 03

White 2000-17 04 04 04

White NHef 2000-17 04 04 04

Black 2000-17 -03 -03 -03

Black NHef 2000-17 -02 -02 -02

APIe 2000-17 01 01 01

AIANeg 2000-17 07 07 07

Hispanicf 2000-17 00 00 00

Table 221

Cancer of the Pancreas (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Both Sexes by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-93 -08 1993-03 02 2003-06 29 2006-17 03 03 03

White 1975-94 -10 1994-17 09 09 09

Black 1975-17 -04 -04 -04

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-17 09 09 09

White 2000-17 10 10 10

White NHef 2000-17 11 11 11

Black 2000-17 04 04 04

Black NHef 2000-17 05 05 05

APIe 2000-17 06 06 06

AIANeg 2000-17 22 22 22

Hispanicf 2000-17 06 06 06

US Cancer Mortalityc 1975-2017

All Races 1975-86 -08 1986-00 -03 2000-17 03 03 03

White 1975-86 -10 1986-97 -03 1997-17 04 04 04

Black 1975-92 05 1992-01 -15 2001-17 -03 -03 -03

US Cancer Mortalityc 2000-2017

All Races 2000-17 03 03 03

White 2000-17 04 04 04

White NHef 2000-17 05 05 05

Black 2000-17 -03 -03 -03

Black NHef 2000-17 -02 -02 -02

APIe 2000-17 01 01 01

AIANeg 2000-02 -74 2002-05 246 2005-09 -80 2009-17 22 10 22

Hispanicf 2000-17 00 00 00

Table 222

Cancer of the Pancreas (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Males by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Regression Program Version 48 April 2020 National Cancer Institute (httpssurveillancecancergovjoinpoint)The APC is the Annual Percent Change based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

a Trends are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)b Trends are from the SEER 21 areas (SEER 9 areas Los Angeles Alaska Native Registry Rural Georgia California excluding

SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York and Massachusetts)c Trends are from US Mortality Files National Center for Health Statistics Centers for Disease Control and Preventiond The AAPC is the Average Annual Percent Change and is based on the APCs calculated by Joinpointe API - AsianPacific Islander AIAN - American IndianAlaska Native NH - Non-Hispanicf Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska

Natives Incidence data for Hispanics and Non-Hispanics are based on NHIA and exclude cases from the Alaska Native Registryg Data for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) counties The APCAAPC is significantly different from zero (plt05)- Joinpoint regression line analysis could not be performed on data series

JP Trend 1 JP Trend 2 JP Trend 3 JP Trend 4 JP Trend 5 JP Trend 6 AAPCd

Years APC Years APC Years APC Years APC Years APC Years APC 2008-17 2013-17

SEER 9 Delay-Adjusted Incidencea 1975-2017

All Races 1975-84 14 1984-96 -05 1996-17 10 10 10

White 1975-84 13 1984-96 -06 1996-17 11 11 11

Black 1975-17 01 01 01

SEER 21 Delay-Adjusted Incidenceb 2000-2017

All Races 2000-17 08 08 08

White 2000-17 09 09 09

White NHef 2000-17 09 09 09

Black 2000-17 04 04 04

Black NHef 2000-17 04 04 04

APIe 2000-17 07 07 07

AIANeg 2000-17 -19 -19 -19

Hispanicf 2000-17 05 05 05

US Cancer Mortalityc 1975-2017

All Races 1975-84 08 1984-03 01 2003-06 10 2006-17 00 00 00

White 1975-83 07 1983-02 01 2002-06 09 2006-17 01 01 01

Black 1975-86 25 1986-17 -03 -03 -03

US Cancer Mortalityc 2000-2017

All Races 2000-17 02 02 02

White 2000-17 03 03 03

White NHef 2000-17 04 04 04

Black 2000-17 -03 -03 -03

Black NHef 2000-17 -02 -02 -02

APIe 2000-17 01 01 01

AIANeg 2000-17 -01 -01 -01

Hispanicf 2000-17 01 01 01

Table 223

Cancer of the Pancreas (Invasive)

Trends in SEER Incidenceab and US Mortalityc Using the Joinpoint Regression Program

1975-2017 With up to Five Joinpoints 2000-2017 With up to Three Joinpoints

Females by RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Reference Cancer Incidence Rates Adjusted for Reporting DelayIndividual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Review

a SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

- Delay-adjusted rate is not shown for observed rates based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-1979 1166 1468 947 1142 1448 923 1635 1986 13641980 1151 1419 961 1106 1369 918 1794 2176 15531981 1168 1354 1017 1139 1326 991 1718 2086 14101982 1172 1381 1018 1141 1346 995 1686 2099 13961983 1219 1466 1044 1175 1407 1012 1813 2305 14901984 1222 1394 1093 1203 1387 1064 1719 1836 16341985 1210 1435 1050 1170 1360 1034 1880 2528 14551986 1168 1378 1021 1137 1354 982 1732 2016 15591987 1161 1381 1011 1110 1338 956 1832 1898 17781988 1166 1372 1021 1111 1336 957 1856 1955 17451989 1133 1288 1007 1098 1266 964 1502 1612 14001990 1128 1281 1006 1102 1246 984 1520 1882 12631991 1139 1291 1021 1104 1262 978 1701 1820 16161992 1162 1322 1034 1133 1290 1002 1734 1977 15751993 1097 1254 970 1050 1198 929 1697 1890 15331994 1137 1326 990 1089 1235 974 1745 2153 14491995 1114 1273 996 1071 1232 957 1815 2040 16311996 1130 1292 993 1091 1248 957 1706 1968 14881997 1149 1307 1019 1102 1256 972 1795 1947 16621998 1148 1311 1023 1125 1298 987 1480 1636 13891999 1110 1258 982 1071 1223 934 1670 1953 14692000 1142 1333 984 1107 1293 956 1575 1816 13382001 1134 1318 999 1106 1308 953 1429 1553 13332002 1177 1306 1058 1159 1328 1008 1612 1492 16242003 1165 1291 1061 1144 1271 1035 1613 1710 15402004 1200 1397 1035 1175 1361 1018 1609 1955 13452005 1210 1384 1069 1179 1352 1034 1721 1862 16502006 1261 1431 1121 1248 1449 1083 1699 1837 15762007 1250 1443 1091 1235 1445 1061 1557 1642 14812008 1276 1460 1125 1241 1427 1085 1730 1935 15842009 1313 1476 1178 1283 1448 1147 1752 2046 15232010 1266 1398 1152 1228 1363 1112 1720 1931 15582011 1251 1460 1081 1230 1439 1054 1617 1785 14892012 1313 1468 1183 1301 1507 1130 1696 1615 17102013 1302 1476 1160 1283 1449 1141 1615 1860 14572014 1300 1491 1140 1297 1484 1136 1676 2015 14202015 1313 1471 1180 1302 1455 1166 1666 1923 14952016 1327 1467 1208 1311 1450 1189 1618 1724 15312017 1323 1508 1159 1313 1527 1119 1615 1621 1579

Table 224Cancer of the Pancreas (Invasive)

Delay-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for diagnosis years 1975-1979 available in web browser version of Cancer Statistics Reviewa SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Diagnosis1975-2017 1205 1391 1057 1174 1366 1021 1666 1874 15071975-1979 1166 1468 947 1142 1448 923 1635 1986 13641980 1151 1419 961 1106 1369 918 1794 2176 15531981 1168 1354 1017 1139 1326 991 1718 2086 14101982 1172 1381 1018 1141 1346 995 1686 2099 13961983 1219 1466 1044 1175 1407 1012 1813 2305 14901984 1222 1394 1093 1203 1387 1064 1719 1836 16341985 1210 1435 1050 1170 1360 1034 1880 2528 14551986 1168 1378 1021 1137 1354 982 1732 2016 15591987 1161 1381 1011 1110 1338 956 1832 1898 17781988 1166 1372 1021 1111 1336 957 1856 1955 17451989 1133 1288 1007 1098 1266 964 1502 1612 14001990 1128 1281 1006 1102 1246 984 1520 1882 12631991 1139 1291 1021 1104 1262 978 1701 1820 16161992 1162 1322 1034 1133 1290 1002 1734 1977 15751993 1097 1254 970 1050 1198 929 1697 1890 15331994 1137 1326 990 1089 1235 974 1745 2153 14491995 1114 1273 996 1071 1232 957 1815 2040 16311996 1130 1292 993 1091 1248 957 1706 1968 14881997 1149 1307 1019 1102 1256 972 1795 1947 16621998 1148 1311 1023 1125 1298 987 1480 1636 13891999 1110 1258 982 1071 1223 934 1670 1953 14692000 1142 1333 984 1107 1293 956 1575 1816 13382001 1134 1318 999 1106 1308 953 1429 1553 13332002 1177 1306 1058 1159 1328 1008 1612 1492 16242003 1165 1291 1061 1144 1271 1035 1613 1710 15402004 1200 1397 1035 1175 1361 1018 1609 1955 13452005 1210 1384 1069 1179 1352 1034 1721 1862 16502006 1261 1431 1121 1248 1449 1083 1699 1837 15762007 1250 1443 1091 1235 1445 1061 1557 1642 14812008 1276 1460 1125 1241 1427 1085 1730 1935 15842009 1312 1475 1178 1283 1447 1147 1751 2045 15222010 1264 1396 1151 1226 1361 1110 1718 1929 15562011 1249 1458 1080 1227 1436 1052 1614 1781 14862012 1310 1465 1181 1297 1502 1127 1692 1610 17062013 1298 1472 1157 1278 1444 1137 1608 1853 14522014 1296 1486 1137 1292 1478 1131 1668 2006 14142015 1307 1464 1174 1293 1445 1158 1656 1912 14862016 1317 1456 1199 1298 1435 1177 1607 1713 15192017 1291 1470 1131 1275 1482 1086 1581 1587 1546

Table 225Cancer of the Pancreas (Invasive)

Age-adjusted SEER Incidencea Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Individual rates for years of death 1975-1979 available in web browser version of Cancer Statistics Reviewa US Mortality Files National Center for Health Statistics Centers for Disease Control and Prevention

Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

Year of Death1975-2017 1076 1264 930 1056 1247 906 1394 1598 12401975-1979 1075 1366 867 1056 1347 850 1304 1626 10661980 1062 1310 883 1036 1285 858 1378 1647 11801981 1070 1316 892 1050 1291 877 1340 1696 10831982 1059 1306 885 1032 1276 860 1409 1707 11911983 1069 1282 913 1036 1240 887 1478 1810 12451984 1080 1296 922 1045 1261 889 1496 1752 13081985 1063 1286 903 1033 1253 876 1443 1729 12401986 1060 1246 923 1030 1216 893 1460 1672 13041987 1059 1252 918 1028 1216 890 1458 1736 12611988 1049 1251 898 1015 1216 865 1452 1705 12661989 1062 1261 917 1025 1222 882 1502 1771 13151990 1069 1259 925 1034 1219 892 1518 1808 13211991 1069 1258 928 1040 1227 899 1455 1693 12791992 1070 1261 927 1035 1223 892 1540 1822 13441993 1066 1241 937 1033 1206 905 1505 1759 13311994 1064 1237 931 1028 1198 895 1516 1769 13381995 1045 1213 918 1021 1191 892 1390 1578 12541996 1047 1208 923 1017 1179 891 1443 1645 12971997 1045 1222 907 1016 1197 876 1457 1639 13141998 1052 1229 915 1023 1202 883 1452 1649 13071999 1062 1232 927 1038 1207 903 1418 1658 12402000 1055 1214 926 1033 1198 899 1405 1579 12702001 1057 1215 930 1040 1205 907 1370 1507 12562002 1056 1222 923 1036 1208 896 1370 1547 12372003 1055 1209 929 1035 1193 904 1384 1553 12522004 1070 1240 931 1051 1223 909 1371 1557 12222005 1083 1242 953 1067 1229 933 1377 1547 12472006 1086 1243 955 1071 1239 932 1370 1488 12642007 1084 1256 946 1067 1245 922 1404 1559 12792008 1096 1251 967 1085 1245 949 1367 1512 12552009 1084 1243 953 1072 1237 937 1358 1500 12372010 1098 1270 958 1088 1263 942 1362 1572 12082011 1088 1250 954 1078 1247 937 1332 1485 12122012 1101 1265 964 1093 1270 943 1340 1451 12482013 1082 1245 946 1073 1242 930 1343 1489 12192014 1093 1263 951 1089 1265 940 1320 1496 11812015 1101 1268 960 1094 1270 942 1338 1487 12232016 1106 1269 970 1100 1270 955 1333 1488 12172017 1110 1290 958 1109 1298 948 1318 1491 1181

Table 226Cancer of the Pancreas (Invasive)

Age-adjusted US Deatha Rates by Year Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a SEER 21 areas Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)unless noted

b US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) unless noted

c Rates are per 100000 and are age-adjusted to the world (WHO 2000-2025) standard million- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER IncidenceAge at DiagnosisAge-Adjusted Rates 2013-2017All ages 131 149 116 131 150 116 153 169 141Under 65 44 51 38 44 50 38 59 67 5165 and over 729 823 656 736 838 655 809 872 766

All ages (WHO world std)c 92 105 81 92 105 80 110 123 100

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 01 - 01 01 - 01 - - -15-19 01 - 02 01 - 02 - - -20-24 02 01 02 02 02 02 - - -25-29 03 02 05 03 02 05 03 - 0530-34 08 07 08 07 06 07 11 10 1235-39 14 15 14 14 14 14 19 20 1840-44 28 30 26 28 30 27 33 36 2945-49 59 68 51 58 66 49 78 87 7050-54 118 138 99 117 137 97 154 176 13555-59 206 240 173 204 238 171 273 316 23660-64 326 387 271 322 382 265 445 534 37265-69 483 568 409 490 575 412 579 685 49870-74 643 746 557 649 759 553 744 839 67675-79 824 914 753 829 933 746 926 948 91180-84 956 1076 872 964 1103 865 1019 1008 102585+ 1024 1098 985 1037 1111 998 1009 1062 987

US MortalityAge at DeathAge-Adjusted Rates 2013-2017All ages 110 127 96 109 127 94 133 149 120Under 65 32 38 26 31 38 25 43 52 3665 and over 650 738 581 650 744 575 754 820 706

All ages (WHO world std)c 64 75 54 63 75 53 80 92 70

Age-Specific Rates 2013-2017lt1 - - - - - - - - -1-4 - - - - - - - - -5-9 - - - - - - - - -10-14 - - - - - - - - -15-19 - - - - - - - - -20-24 00 00 00 00 - - - - -25-29 01 01 01 01 01 00 - - -30-34 02 02 02 02 02 02 03 03 0335-39 07 08 05 07 09 04 08 10 0640-44 16 19 13 16 20 12 20 24 1645-49 39 47 31 39 46 31 51 64 3950-54 84 101 68 83 100 66 116 134 9955-59 157 189 127 153 185 122 219 258 18560-64 258 311 209 253 306 203 354 434 28865-69 382 457 315 380 456 311 478 571 40770-74 537 626 461 539 632 458 631 724 56375-79 715 808 640 712 814 630 848 931 79380-84 909 1007 840 909 1018 829 1020 1038 101085+ 1062 1156 1013 1065 1171 1008 1146 1123 1156

Table 227Cancer of the Pancreas (Invasive)

SEER Incidencea and US Deathb Rates Age-Adjusted and Age-Specific Rates by Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 1 1 2 1 0 31970-1973a - - - 2 2 2 2 0 31975-1977b 25 26 22 25 27 23 23 25 191978-1980b 29 27 30 25 26 25 58 45 701981-1983b 27 24 31 25 21 30 36 37 321984-1986b 29 23 35 26 21 31 47 39 531987-1989b 35 33 37 32 30 33 55 51 581990-1992b 43 41 45 44 42 45 36 32 401993-1995b 40 37 43 39 36 42 37 36 371996-1998b 43 46 41 41 46 36 34 31 351999-2001b 51 52 50 50 55 45 56 37 742002-2004b 56 53 59 57 56 58 45 30 572005-2009b 77 78 76 78 78 77 64 68 612010-2016b 105f 107f 102f 104f 107f 102f 103f 105f 101f

5-Year Period Survival (Percent)cd

2016 110 110 110 108 109 107 106 98 112

Stage Distribution () 2010-2016ce

All StagesNumber of cases 65128 33078 32050 51197 26465 24732 8087 3741 4346Percent 100 100 100 100 100 100 100 100 100Localized 11 10 12 11 10 12 11 9 12Regional 30 29 30 30 30 30 28 26 29Distant 52 55 50 52 54 50 56 59 53UnstagedUnknown 7 6 8 7 6 8 6 5 7

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 406 326 489 413 342 491 377 233 490Ages 45-54 171 152 196 167 146 198 162 155 171Ages 55-64 113 106 123 113 108 121 99 89 112Ages 65-74 91 92 90 91 92 90 80 74 85Ages 75+ 47 52 44 48 53 44 45 27 51Ages lt65 152 134 176 150 134 173 139 117 164Ages 65+ 68 74 63 68 74 63 64 58 67

StageeAll Stages 100 100 100 98 99 98 101 92 108Localized 394 409 381 392 412 373 360 335 375Regional 133 140 126 132 137 125 145 153 138Distant 29 29 30 29 29 30 29 28 29UnstagedUnknown 61 66 56 54 62 45 111 92 125

Table 228Cancer of the Pancreas (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on End Results data from a series of hospital registries and one population-based registryb SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)

Based on follow-up of patients into 2017 Expected survival rates are derived from the US Annual Life Tablesc SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-Monterey

Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey andGeorgia excluding ATLRG) Expected survival rates are derived from life tables by socio-economic status geography and racedeveloped by the SEER programBased on follow-up of patients into 2017

d Period survival provides a 2016 estimate of survival by piecing together the most recent conditional survival estimatesfrom several cohorts It is computed here using three year calendar blocks (2010-2012 0-1 year survival)(2009-2011 1-2 year survival) (2008-2010 2-3 year survival) (2007-2009 3-4 year survival) (2006-2008 4-5 years survival)

e Stage at diagnosis is classified using SEER Summary Stage 2000 Stage distribution percentages may not sum to 100 due to roundingf The difference between 1975-1977 and 2010-2016 is statistically significant (plt05)g The standard error is between 5 and 10 percentage pointsh The standard error is greater than 10 percentage points- Statistic could not be calculated due to fewer than 25 cases during the time period

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

5-Year Relative Survival (Percent)Year of Diagnosis1960-1963a - - - 1 1 2 1 0 31970-1973a - - - 2 2 2 2 0 31975-1977b 25 26 22 25 27 23 23 25 191978-1980b 29 27 30 25 26 25 58 45 701981-1983b 27 24 31 25 21 30 36 37 321984-1986b 29 23 35 26 21 31 47 39 531987-1989b 35 33 37 32 30 33 55 51 581990-1992b 43 41 45 44 42 45 36 32 401993-1995b 40 37 43 39 36 42 37 36 371996-1998b 43 46 41 41 46 36 34 31 351999-2001b 51 52 50 50 55 45 56 37 742002-2004b 56 53 59 57 56 58 45 30 572005-2009b 77 78 76 78 78 77 64 68 612010-2016b 105f 107f 102f 104f 107f 102f 103f 105f 101f

5-Year Period Survival (Percent)cd

2016 110 110 110 108 109 107 106 98 112

Stage Distribution () 2010-2016ce

All StagesNumber of cases 65128 33078 32050 51197 26465 24732 8087 3741 4346Percent 100 100 100 100 100 100 100 100 100Localized 11 10 12 11 10 12 11 9 12Regional 30 29 30 30 30 30 28 26 29Distant 52 55 50 52 54 50 56 59 53UnstagedUnknown 7 6 8 7 6 8 6 5 7

5-Year Relative Survival (Percent) 2010-2016c

Age at DiagnosisAges lt45 406 326 489 413 342 491 377 233 490Ages 45-54 171 152 196 167 146 198 162 155 171Ages 55-64 113 106 123 113 108 121 99 89 112Ages 65-74 91 92 90 91 92 90 80 74 85Ages 75+ 47 52 44 48 53 44 45 27 51Ages lt65 152 134 176 150 134 173 139 117 164Ages 65+ 68 74 63 68 74 63 64 58 67

StageeAll Stages 100 100 100 98 99 98 101 92 108Localized 394 409 381 392 412 373 360 335 375Regional 133 140 126 132 137 125 145 153 138Distant 29 29 30 29 29 30 29 28 29UnstagedUnknown 61 66 56 54 62 45 111 92 125

Table 228Cancer of the Pancreas (Invasive)

5-Year Relative and Period Survival (Percent) by Race Sex Diagnosis Year Stage and Age

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 143 158 170 185 178 190 199 193 223 217 238 250 228 228 267 258 280 298 298 303 315 348 356 350 362 3732-year 59 63 67 86 83 93 98 88 105 110 114 119 115 119 129 133 139 151 159 169 163 198 206 197 2043-year 36 41 47 58 53 62 71 56 66 73 74 85 76 83 91 95 98 105 119 120 117 148 156 1524-year 30 33 38 48 40 48 55 44 57 61 61 68 58 64 72 82 84 86 100 100 94 126 1305-year 25 28 33 42 36 42 49 38 51 52 51 62 51 55 64 76 77 78 87 84 82 1156-year 23 25 29 40 32 38 44 37 46 47 47 57 46 50 58 70 71 72 82 76 767-year 22 23 27 36 31 35 43 34 43 43 42 50 43 47 55 62 65 66 75 718-year 19 21 25 34 27 34 41 30 40 39 39 47 41 44 51 60 58 61 709-year 18 20 22 32 27 33 40 27 38 38 38 46 38 42 48 59 53 6010-year 18 19 22 30 25 32 39 26 36 37 35 45 35 41 44 57 5011-year 17 17 21 28 25 29 38 25 33 36 33 41 33 41 40 5512-year 17 17 21 27 23 28 36 24 32 33 32 40 33 41 3913-year 16 16 20 26 22 27 33 22 31 31 32 38 31 3914-year 16 16 19 25 19 27 31 19 31 28 30 38 2915-year 15 15 18 24 18 27 30 19 30 27 27 3516-year 15 14 17 22 17 22 29 18 27 26 2517-year 14 14 17 22 15 19 27 15 27 2518-year 13 13 17 22 14 19 27 13 2419-year 13 13 16 21 14 19 27 1220-year 12 13 16 20 13 19 27

Table 229Cancer of the Pancreas (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males and Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 143 149 167 178 169 198 212 188 228 219 232 248 243 252 257 270 282 314 293 299 327 345 360 361 356 3702-year 58 58 62 84 73 109 99 91 98 114 120 111 116 126 119 137 136 162 166 166 178 197 208 203 2023-year 35 38 44 58 42 71 70 56 60 70 80 82 76 82 79 98 91 115 128 121 127 146 156 1614-year 30 30 33 46 35 58 55 45 55 59 64 69 56 59 56 82 78 99 109 101 105 126 1315-year 26 25 29 40 30 51 47 39 49 52 55 61 46 51 52 76 72 90 95 85 92 1156-year 24 22 24 38 27 47 39 37 40 49 50 53 42 45 47 71 64 85 89 75 867-year 23 19 23 34 27 42 34 34 39 45 46 48 40 41 43 61 60 76 82 698-year 20 17 21 31 24 42 34 32 38 39 42 44 38 38 40 60 52 69 779-year 19 16 18 30 22 40 33 28 36 37 41 43 34 36 37 59 48 6910-year 18 15 17 27 21 38 32 28 36 35 39 42 28 35 34 56 4411-year 17 15 16 26 20 32 29 28 32 35 37 36 26 35 29 5312-year 16 15 16 26 18 30 28 26 31 29 34 35 26 34 2713-year 16 14 15 25 17 30 26 25 30 27 34 35 22 3214-year 16 14 15 24 12 29 24 23 30 24 34 35 2115-year 16 13 13 23 12 28 22 23 30 23 33 2916-year 16 13 13 21 12 20 19 23 26 23 3017-year 14 13 13 21 08 17 19 19 26 2318-year 13 13 12 21 07 17 19 14 2219-year 12 13 12 21 07 16 18 1420-year 11 12 12 19 02 16 18

Table 2210Cancer of the Pancreas (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Males

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Based on the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta)Expected survival rates are derived from the US Annual Life Tables

1975- 1980- 1985- 1990-1979 1984 1989 1994 1995 1996 1997 1998 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016

SurvivalTime

1-year 143 166 173 191 186 182 187 198 219 216 243 251 215 204 279 247 277 282 302 308 301 352 352 338 368 3752-year 59 67 72 87 92 78 98 85 111 105 108 127 113 112 140 129 142 140 152 172 146 200 204 192 2063-year 38 44 51 58 62 54 72 57 71 76 67 87 76 84 103 92 105 95 110 119 106 150 156 1444-year 30 36 43 49 44 39 55 43 58 63 58 67 60 70 88 81 89 73 91 100 82 125 1295-year 24 32 37 44 42 34 52 37 53 52 46 63 55 60 76 76 83 65 79 83 71 1166-year 23 28 34 41 37 30 49 37 51 45 43 60 50 56 70 70 78 60 74 76 667-year 20 27 32 38 34 28 49 34 47 41 37 52 46 53 67 63 70 56 68 738-year 18 25 28 37 30 26 48 28 41 39 35 50 44 50 62 60 64 52 639-year 18 23 27 34 30 25 46 25 39 38 34 48 42 48 59 59 59 5010-year 17 22 26 32 29 25 46 24 37 37 31 47 41 47 54 58 5711-year 17 20 25 29 29 25 46 21 34 37 30 45 39 47 51 5712-year 17 19 25 27 28 25 43 21 32 37 29 44 38 47 5013-year 16 18 24 27 26 23 38 19 32 35 28 41 38 4714-year 15 17 24 26 24 23 38 14 31 32 24 41 3715-year 13 16 23 23 22 23 37 14 30 30 21 4016-year 13 15 20 23 21 23 37 10 28 28 2117-year 13 15 20 23 21 21 35 10 27 2718-year 13 14 20 22 20 21 35 10 2619-year 13 14 20 22 20 21 35 0820-year 13 14 20 21 20 21 35

Table 2211Cancer of the Pancreas (Invasive)

SEERa Relative Survival (Percent)By Year of Diagnosis

All Races Females

Year of Diagnosis

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 000 165 138 Asian 0 000 000 001 164 141

10 000 000 002 167 139 Pacific 10 000 000 001 165 142

20 000 001 006 167 140 Islander 20 000 001 005 165 142

30 001 006 021 168 141 30 001 005 015 165 143

40 005 020 056 169 143 40 004 014 040 165 143

50 016 053 108 169 144 50 011 037 085 163 143

60 039 097 146 161 140 60 027 076 128 157 140

70 065 120 - 138 125 70 053 109 - 139 128

80 072 - - 096 094 80 066 - - 101 103

White 0 000 000 000 164 138 American 0 000 000 000 139 103

10 000 000 002 166 139 Indian 10 000 000 001 140 104

20 000 001 006 166 139 Alaska 20 000 001 006 141 105

30 001 006 021 167 141 Nativea 30 001 006 017 143 107

40 005 020 056 169 142 40 005 016 040 146 110

50 016 053 108 168 143 50 012 037 074 147 113

60 039 097 146 161 140 60 026 067 122 145 115

70 066 120 - 137 124 70 046 108 - 135 106

80 073 - - 095 093 80 083 - - 118 086

Black 0 000 000 000 168 145 Hispanicb 0 000 000 000 170 131

10 000 000 002 171 148 10 000 000 002 171 132

20 000 002 008 172 149 20 000 001 005 172 133

30 002 008 027 174 151 30 001 005 019 173 134

40 006 026 069 176 153 40 004 018 050 173 135

50 020 065 120 176 155 50 014 047 098 172 135

60 048 108 153 169 152 60 034 088 140 165 132

70 071 125 - 143 136 70 059 117 - 144 120

80 075 - - 101 104 80 071 - - 105 093

Table 2212

Cancer of the Pancreas (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Both Sexes 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 000 168 140 Asian 0 000 000 000 164 139

10 000 000 001 169 142 Pacific 10 000 000 001 165 141

20 000 001 006 170 143 Islander 20 000 001 005 166 141

30 001 006 024 172 145 30 001 005 018 166 142

40 005 023 064 174 147 40 004 017 045 167 142

50 019 060 119 174 148 50 013 042 091 165 142

60 045 107 154 167 145 60 030 081 129 158 139

70 072 127 - 141 128 70 056 107 - 139 126

80 076 - - 096 094 80 064 - - 102 102

White 0 000 000 000 169 141 American 0 000 000 000 170 098

10 000 000 001 170 143 Indian 10 000 000 001 172 099

20 000 001 006 171 144 Alaska 20 000 001 005 173 100

30 001 006 024 173 146 Nativea 30 000 004 018 177 102

40 005 023 064 175 148 40 004 018 048 183 106

50 018 060 120 175 149 50 015 047 099 188 111

60 045 109 156 168 146 60 035 092 157 190 113

70 074 129 - 142 128 70 067 143 - 181 102

80 077 - - 096 094 80 107 - - 160 072

Black 0 000 000 000 159 136 Hispanicb 0 000 000 000 165 127

10 000 000 002 163 139 10 000 000 001 167 128

20 000 002 008 164 140 20 000 001 005 167 129

30 001 008 030 166 143 30 001 005 020 169 130

40 007 029 077 169 147 40 004 019 054 170 131

50 023 074 126 170 149 50 015 051 105 170 132

60 056 114 152 162 146 60 038 095 143 164 129

70 073 120 - 134 127 70 064 118 - 142 116

80 073 - - 093 095 80 071 - - 102 090

Table 2213

Cancer of the Pancreas (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Males 2015-2017 By RaceEthnicity

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Devcan 678 April 2020 National Cancer Institute (httpssurveillancecancergovdevcan)Source Incidence data are from the SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta

San Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts) Mortality data are from the NCHS public use data file for the total US

a Underlying incidence and mortality data for American IndianAlaska Native are based on the PRCDA(PurchasedReferred Care DeliveryAreas) counties

b Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska NativesUnderlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registry

- Statistic could not be calculatedA percent of 000 represents a value that is below 0005

Risk of Being Risk of Being

Race Current Diagnosed with Cancer Risk of Dying Race Current Diagnosed with Cancer Risk of Dying

Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer Ethnicity Age +10 yrs +20 yrs +30 yrs Ever from Cancer

All Races 0 000 000 001 162 136 Asian 0 000 000 001 163 142

10 000 001 002 164 137 Pacific 10 000 001 001 164 143

20 000 002 006 164 137 Islander 20 000 001 004 164 143

30 001 005 019 164 138 30 001 004 013 164 144

40 004 017 049 165 139 40 003 013 036 164 144

50 014 045 097 163 140 50 009 033 080 162 144

60 033 087 138 156 136 60 024 072 128 156 141

70 059 115 - 135 122 70 051 109 - 139 131

80 070 - - 095 093 80 067 - - 101 104

White 0 000 000 001 160 134 American 0 000 000 000 112 106

10 000 001 002 161 135 Indian 10 000 000 001 113 108

20 000 002 005 161 135 Alaska 20 000 001 007 114 108

30 001 005 018 162 136 Nativea 30 001 007 016 115 109

40 004 017 048 162 137 40 005 015 032 116 111

50 013 045 096 161 138 50 010 027 052 114 114

60 033 087 136 154 134 60 019 045 091 110 114

70 059 114 - 133 120 70 029 081 - 101 107

80 069 - - 094 092 80 066 - - 091 094

Black 0 000 000 001 176 152 Hispanicb 0 000 000 001 175 135

10 000 001 002 179 155 10 000 001 002 176 136

20 001 002 008 179 156 20 000 002 006 176 136

30 002 007 024 180 157 30 001 005 018 176 137

40 006 023 061 180 158 40 004 016 046 176 137

50 018 057 115 180 160 50 013 042 093 174 137

60 043 104 154 173 156 60 031 083 138 167 134

70 070 128 - 149 141 70 056 115 - 146 122

80 076 - - 105 110 80 071 - - 108 095

Table 2214

Cancer of the Pancreas (Invasive)

Risk of Being Diagnosed With Cancer in 10 20 and 30 Years

Lifetime Risk of Being Diagnosed with Cancer Given Alive and Cancer-Free at Current Age and

Lifetime Risk of Dying from Cancer Given Alive at Current Age

Females 2015-2017 By RaceEthnicity

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

The AAPC is the Average Annual Percent Change over the time interval The AAPCs are calculated bythe Joinpoint Regression Program Version 48 April 2020 National Cancer Institute

- Statistic not shown Rate based on less than 16 cases for the time intervalTrend based on less than 10 cases for at least one year within the time interval

a Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130) Trendsare based on rates age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico SeattleUtah and AtlantaThe SEER 21 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the AlaskaNative Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts

c The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 3 Joinpoints overdiagnosis years 2000-2017

d The 2008-2017 AAPC estimates are based on a Joinpoint analysis with up to 5 Joinpoints overdiagnosis years 1975-2017

e Hispanic and Non-Hispanic are not mutually exclusive from whites blacks AsianPacificIslanders and American IndiansAlaska Natives Incidence data for Hispanics and Non-Hispanicsare based on NHIA and exclude cases from the Alaska Native Registry

f Incidence data for American IndianAlaska Native are based on the PurchasedReferred CareDelivery Area (PRCDA) counties

g US Mortality Files National Center for Health Statistics CDCh The 2008-2017 mortality AAPCs are based on a Joinpoint analysis using years of death 2000-2017 The APC is significantly different from zero (plt05)

SEER Incidence SEER 21 Areasb SEER 21 Areasb SEER 9 Areasb

Rate 2013-2017 Trend 2008-2017c Trend 2008-2017d

Rate per 100000 persons AAPC () AAPC ()

Total Males Females Total Males Females Total Males Females RaceEthnicity

All Races 131 149 116 05 05 07 02 02 09

White 131 150 116 03 06 08 04 04 10White Hispanice 120 130 112 04 04 04 - - -White Non-Hispanice 133 153 116 04 07 08 - - -

Black 153 169 141 03 03 03 -01 -04 01

AsianPacific Islander 100 110 92 05 04 06 - - -

Amer IndAlaska Natf 100 129 78 -01 19 -22 - - -

Hispanice 116 125 108 04 05 04 - - -

US Mortalityg Rate 2013-2017 Trend 2008-2017h

Rate per 100000 persons AAPC ()

Total Males Females Total Males FemalesRaceEthnicity

All Races 110 127 96 03 03 02

White 109 127 94 04 04 03White Hispanice 90 99 82 02 02 02White Non-Hispanice 111 130 96 04 05 04

Black 133 149 120 -03 -03 -03

AsianPacific Islander 76 82 71 01 01 01

Amer IndAlaska NatTotal US 66 72 61 00 02 -03PRCDA Counties 89 103 78 07 10 -01Non-PRCDA Counties 41 39 42 -09 -15 -03

Hispanice 85 94 78 00 00 01

Table 2215Cancer of the Pancreas (Invasive)

SEER Incidence and US MortalityAge-Adjusted Rates and Trendsa

By RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1188 1348 1052 1215 1383 1070 1452 1653 1301Greater Bay Area 1195 1343 1070 1248 1406 1108 1594 1839 1420San Francisco-Oakland 1208 1365 1077 1251 1433 1091 1604 1807 1456San Jose-Monterey 1169 1303 1056 1241 1359 1137 1544 2090 1110

Los Angeles 1160 1303 1045 1181 1329 1059 1436 1551 1353Greater California 1197 1370 1049 1218 1397 1063 1399 1656 1187

Connecticut 1355 1546 1194 1350 1548 1183 1445 1527 1366Detroit 1539 1734 1378 1472 1676 1298 1853 2110 1665Georgia 1305 1488 1156 1241 1448 1064 1556 1687 1465Atlanta 1328 1513 1191 1229 1444 1063 1572 1701 1484Rural Georgia 1233 1441 1064 1170 1531 851 1433 1458 1435Greater Georgia 1305 1490 1149 1254 1460 1072 1562 1695 1469

Hawaii 1371 1551 1211 1347 1455 1213 - - -Idaho 1391 1578 1216 1401 1601 1215 - - -Iowa 1344 1549 1163 1342 1552 1156 1700 1762 1642Kentucky 1350 1533 1198 1335 1525 1178 1646 1661 1589Louisiana 1419 1632 1245 1353 1581 1166 1638 1818 1492Massachusetts 1307 1482 1167 1305 1487 1160 1366 1531 1241New Jersey 1437 1619 1288 1469 1667 1306 1535 1642 1442New Mexico 1123 1273 995 1140 1273 1022 1272 1628 -New York 1420 1620 1257 1441 1662 1258 1488 1625 1379Seattle-Puget Sound 1281 1411 1168 1286 1396 1187 1563 1986 1172Utah 1079 1242 931 1075 1238 927 - - -

SEER 9 Areasb 1302 1470 1159 1287 1457 1137 1624 1808 1486SEER 13 Areasb 1263 1425 1128 1263 1426 1121 1576 1750 1449SEER 18 Areasb 1283 1454 1139 1283 1461 1130 1561 1724 1436SEER 21 Areasb 1310 1487 1163 1314 1500 1156 1534 1690 1415

Table 2216Cancer of the Pancreas (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 1034 1179 912 1070 1227 936 1257 1441 1115Greater Bay Area 983 1100 884 1037 1157 933 1316 1553 1137San Francisco-Oakland 991 1109 891 1037 1151 937 1325 1542 1156San Jose-Monterey 968 1084 869 1036 1167 923 1305 1678 -

Los Angeles 1045 1175 940 1071 1217 951 1291 1423 1197Greater California 1047 1208 909 1079 1251 930 1191 1396 1017

Connecticut 1069 1221 945 1075 1238 941 1155 1223 1094Detroit 1236 1373 1121 1202 1366 1059 1430 1498 1371Georgia 1064 1233 927 1033 1222 875 1217 1347 1117Atlanta 1034 1175 926 988 1142 867 1179 1346 1063Rural Georgia 988 1225 785 992 1269 745 1036 - -Greater Georgia 1086 1266 937 1055 1255 883 1264 1364 1179

Hawaii 1098 1239 978 1236 1304 1145 - - -Idaho 1154 1322 998 1170 1350 1001 - - -Iowa 1119 1300 964 1114 1298 958 1537 1577 1452Kentucky 1121 1296 976 1112 1290 964 1348 1471 1215Louisiana 1275 1482 1104 1208 1436 1022 1494 1660 1348Massachusetts 1129 1298 993 1157 1327 1020 1004 1272 801New Jersey 1131 1279 1011 1160 1316 1031 1253 1401 1147New Mexico 979 1122 854 996 1127 878 1275 1596 -New York 1111 1277 978 1149 1327 1002 1106 1266 991Seattle-Puget Sound 1047 1191 923 1064 1199 944 1335 1677 1065Utah 948 1080 830 950 1078 835 - - -

SEER 9 Areasb 1063 1205 944 1068 1213 942 1272 1410 1165SEER 13 Areasb 1054 1191 940 1068 1211 944 1274 1416 1168SEER 18 Areasb 1079 1231 951 1089 1251 951 1294 1441 1179SEER 21 Areasb 1089 1245 960 1106 1271 966 1235 1391 1115

Total US 1099 1268 957 1094 1270 943 1330 1491 1204

Table 2217Cancer of the Pancreas (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1099 002

High Five StatesMississippi 1296 028 01(0105) 1796c

DC 1292 064 02(0131) 1759c

Louisiana 1275 023 03(0105) 1596c

Michigan 1214 014 04(0210) 1050Delaware 1201 045 05(0137) 927

Low Five StatesArizona 1014 016 47(3650) -774North Dakota 1013 049 48(1051) -788New Mexico 979 028 49(3651) -1093Utah 948 028 50(4351) -1372Colorado 922 018 51(4851) -1615c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1147 020 13(0533) 439 Montana 1052 040 40(0750) -428Alaska 1065 063 37(0351) -311 Nebraska 1107 032 29(0546) 071Arizona 1014 016 47(3650) -774 Nevada 1054 026 39(1649) -407Arkansas 1099 025 31(0745) 003 New Hampshire 1037 035 43(1350) -569California 1034 007 44(3748) -592 New Jersey 1131 015 16(0833) 292Colorado 922 018 51(4851) -1615c New Mexico 979 028 49(3651) -1093Connecticut 1069 022 36(1748) -272 New York 1111 010 26(1535) 110Delaware 1201 045 05(0137) 927 North Carolina 1102 014 30(1439) 024DC 1292 064 02(0131) 1759c North Dakota 1013 049 48(1051) -788Florida 1043 008 42(3547) -511 Ohio 1173 013 07(0419) 669Georgia 1064 015 38(2646) -315 Oklahoma 1099 022 32(0943) 003Hawaii 1098 035 33(0548) -007 Oregon 1156 022 11(0432) 520Idaho 1154 036 12(0340) 502 Pennsylvania 1196 012 06(0312) 878Illinois 1111 012 25(1236) 112 Rhode Island 1168 043 09(0141) 628Indiana 1159 018 10(0429) 546 South Carolina 1138 020 15(0536) 354Iowa 1119 024 22(0641) 177 South Dakota 1116 047 23(0349) 153Kansas 1120 026 21(0541) 192 Tennessee 1122 017 19(0837) 205Kentucky 1121 021 20(0639) 196 Texas 1023 009 45(3849) -697Louisiana 1275 023 03(0105) 1596c Utah 948 028 50(4351) -1372Maine 1111 034 27(0447) 109 Vermont 1075 052 34(0450) -222Maryland 1145 019 14(0533) 421 Virginia 1109 016 28(1139) 087Massachusetts 1129 017 17(0735) 273 Washington 1069 017 35(2046) -270Michigan 1214 014 04(0210) 1050 West Virginia 1044 029 41(1850) -504Minnesota 1113 019 24(0839) 125 Wisconsin 1170 018 08(0425) 650Mississippi 1296 028 01(0105) 1796c Wyoming 1016 056 46(0751) -757Missouri 1123 018 18(0837) 217

Table 2218Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 10 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1268 004

High Five StatesMississippi 1540 047 01(0107) 2148c

Louisiana 1482 037 02(0109) 1692c

DC 1482 107 03(0144) 1690c

Pennsylvania 1413 020 04(0212) 1147c

Delaware 1409 073 05(0140) 1114c

Low Five StatesMontana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c

New Mexico 1122 045 49(2951) -1150c

Utah 1080 044 50(3651) -1477c

Colorado 1073 030 51(4351) -1540c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1332 033 12(0435) 508 Montana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c Nebraska 1319 053 17(0244) 406Arizona 1160 025 46(3350) -850 Nevada 1173 040 42(2251) -751Arkansas 1268 040 28(0646) 006 New Hampshire 1205 056 39(0951) -498California 1179 012 41(3548) -699 New Jersey 1279 024 26(1038) 091Colorado 1073 030 51(4351) -1540c New Mexico 1122 045 49(2951) -1150c

Connecticut 1221 036 36(1448) -365 New York 1277 016 27(1436) 077Delaware 1409 073 05(0140) 1114c North Carolina 1296 023 23(0836) 222DC 1482 107 03(0144) 1690c North Dakota 1216 081 37(0351) -410Florida 1214 014 38(2944) -421 Ohio 1328 021 13(0630) 472Georgia 1233 024 32(1845) -273 Oklahoma 1261 036 29(0946) -051Hawaii 1239 056 31(0550) -229 Oregon 1334 035 11(0335) 520Idaho 1322 056 16(0245) 425 Pennsylvania 1413 020 04(0212) 1147c

Illinois 1309 021 19(0733) 322 Rhode Island 1394 071 06(0141) 995Indiana 1363 029 10(0327) 753 South Carolina 1323 033 14(0436) 435Iowa 1300 039 20(0441) 251 South Dakota 1223 073 35(0351) -355Kansas 1258 042 30(0747) -073 Tennessee 1290 028 24(0839) 172Kentucky 1296 034 22(0540) 222 Texas 1163 015 44(3649) -825Louisiana 1482 037 02(0109) 1692c Utah 1080 044 50(3651) -1477c

Maine 1194 054 40(0951) -581 Vermont 1231 083 33(0251) -288Maryland 1366 031 08(0328) 775 Virginia 1315 026 18(0634) 370Massachusetts 1298 027 21(0737) 237 Washington 1228 027 34(1846) -314Michigan 1387 023 07(0218) 943 West Virginia 1161 046 45(1951) -840Minnesota 1281 030 25(0841) 109 Wisconsin 1363 030 09(0329) 755Mississippi 1540 047 01(0107) 2148c Wyoming 1168 088 43(0351) -787Missouri 1323 029 15(0534) 434

Table 2219Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 957 003

High Five StatesDC 1144 079 01(0140) 1953c

Louisiana 1104 028 02(0111) 1536c

Mississippi 1104 034 03(0115) 1531c

Michigan 1067 018 04(0113) 1143Ohio 1041 016 05(0219) 879

Low Five StatesWyoming 864 071 47(0451) -974New Mexico 854 036 48(2451) -1076North Dakota 833 061 49(0951) -1297Utah 830 036 50(3451) -1331Colorado 792 023 51(4651) -1723c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 987 025 19(0440) 313 Montana 955 053 30(0250) -018Alaska 1014 084 09(0151) 596 Nebraska 927 040 41(0650) -320Arizona 881 020 45(3150) -800 Nevada 942 034 36(0649) -162Arkansas 949 031 33(0648) -090 New Hampshire 878 044 46(1151) -832California 912 009 42(3247) -474 New Jersey 1011 018 10(0429) 565Colorado 792 023 51(4651) -1723c New Mexico 854 036 48(2451) -1076Connecticut 945 027 35(0948) -131 New York 978 012 22(0935) 217Delaware 1035 056 07(0147) 808 North Carolina 945 017 34(1444) -124DC 1144 079 01(0140) 1953c North Dakota 833 061 49(0951) -1297Florida 895 011 44(3549) -648 Ohio 1041 016 05(0219) 879Georgia 927 018 40(1947) -316 Oklahoma 963 028 28(0646) 059Hawaii 978 045 23(0248) 217 Oregon 1008 028 11(0238) 535Idaho 998 046 14(0148) 424 Pennsylvania 1017 015 08(0426) 619Illinois 954 015 31(1442) -034 Rhode Island 993 052 16(0149) 376Indiana 992 022 18(0539) 360 South Carolina 985 025 20(0541) 290Iowa 964 030 27(0646) 071 South Dakota 998 060 13(0149) 424Kansas 998 033 15(0243) 422 Tennessee 981 021 21(0641) 243Kentucky 976 026 25(0543) 191 Texas 902 011 43(3348) -578Louisiana 1104 028 02(0111) 1536c Utah 830 036 50(3451) -1331Maine 1037 045 06(0142) 832 Vermont 949 065 32(0151) -088Maryland 976 023 24(0642) 194 Virginia 939 019 37(1446) -195Massachusetts 993 021 17(0538) 371 Washington 934 021 39(1447) -240Michigan 1067 018 04(0113) 1143 West Virginia 937 037 38(0650) -211Minnesota 967 024 26(0744) 107 Wisconsin 1002 023 12(0437) 464Mississippi 1104 034 03(0115) 1531c Wyoming 864 071 47(0451) -974Missouri 956 022 29(0945) -012

Table 2220Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and Atlanta

The SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Incidence Ratesa 2013-2017

California 1188 1348 1052 1215 1383 1070 1452 1653 1301Greater Bay Area 1195 1343 1070 1248 1406 1108 1594 1839 1420San Francisco-Oakland 1208 1365 1077 1251 1433 1091 1604 1807 1456San Jose-Monterey 1169 1303 1056 1241 1359 1137 1544 2090 1110

Los Angeles 1160 1303 1045 1181 1329 1059 1436 1551 1353Greater California 1197 1370 1049 1218 1397 1063 1399 1656 1187

Connecticut 1355 1546 1194 1350 1548 1183 1445 1527 1366Detroit 1539 1734 1378 1472 1676 1298 1853 2110 1665Georgia 1305 1488 1156 1241 1448 1064 1556 1687 1465Atlanta 1328 1513 1191 1229 1444 1063 1572 1701 1484Rural Georgia 1233 1441 1064 1170 1531 851 1433 1458 1435Greater Georgia 1305 1490 1149 1254 1460 1072 1562 1695 1469

Hawaii 1371 1551 1211 1347 1455 1213 - - -Idaho 1391 1578 1216 1401 1601 1215 - - -Iowa 1344 1549 1163 1342 1552 1156 1700 1762 1642Kentucky 1350 1533 1198 1335 1525 1178 1646 1661 1589Louisiana 1419 1632 1245 1353 1581 1166 1638 1818 1492Massachusetts 1307 1482 1167 1305 1487 1160 1366 1531 1241New Jersey 1437 1619 1288 1469 1667 1306 1535 1642 1442New Mexico 1123 1273 995 1140 1273 1022 1272 1628 -New York 1420 1620 1257 1441 1662 1258 1488 1625 1379Seattle-Puget Sound 1281 1411 1168 1286 1396 1187 1563 1986 1172Utah 1079 1242 931 1075 1238 927 - - -

SEER 9 Areasb 1302 1470 1159 1287 1457 1137 1624 1808 1486SEER 13 Areasb 1263 1425 1128 1263 1426 1121 1576 1750 1449SEER 18 Areasb 1283 1454 1139 1283 1461 1130 1561 1724 1436SEER 21 Areasb 1310 1487 1163 1314 1500 1156 1534 1690 1415

Table 2216Cancer of the Pancreas (Invasive)

Age-Adjusted SEER Incidence Ratesa

By Registry Race and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 1034 1179 912 1070 1227 936 1257 1441 1115Greater Bay Area 983 1100 884 1037 1157 933 1316 1553 1137San Francisco-Oakland 991 1109 891 1037 1151 937 1325 1542 1156San Jose-Monterey 968 1084 869 1036 1167 923 1305 1678 -

Los Angeles 1045 1175 940 1071 1217 951 1291 1423 1197Greater California 1047 1208 909 1079 1251 930 1191 1396 1017

Connecticut 1069 1221 945 1075 1238 941 1155 1223 1094Detroit 1236 1373 1121 1202 1366 1059 1430 1498 1371Georgia 1064 1233 927 1033 1222 875 1217 1347 1117Atlanta 1034 1175 926 988 1142 867 1179 1346 1063Rural Georgia 988 1225 785 992 1269 745 1036 - -Greater Georgia 1086 1266 937 1055 1255 883 1264 1364 1179

Hawaii 1098 1239 978 1236 1304 1145 - - -Idaho 1154 1322 998 1170 1350 1001 - - -Iowa 1119 1300 964 1114 1298 958 1537 1577 1452Kentucky 1121 1296 976 1112 1290 964 1348 1471 1215Louisiana 1275 1482 1104 1208 1436 1022 1494 1660 1348Massachusetts 1129 1298 993 1157 1327 1020 1004 1272 801New Jersey 1131 1279 1011 1160 1316 1031 1253 1401 1147New Mexico 979 1122 854 996 1127 878 1275 1596 -New York 1111 1277 978 1149 1327 1002 1106 1266 991Seattle-Puget Sound 1047 1191 923 1064 1199 944 1335 1677 1065Utah 948 1080 830 950 1078 835 - - -

SEER 9 Areasb 1063 1205 944 1068 1213 942 1272 1410 1165SEER 13 Areasb 1054 1191 940 1068 1211 944 1274 1416 1168SEER 18 Areasb 1079 1231 951 1089 1251 951 1294 1441 1179SEER 21 Areasb 1089 1245 960 1106 1271 966 1235 1391 1115

Total US 1099 1268 957 1094 1270 943 1330 1491 1204

Table 2217Cancer of the Pancreas (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1099 002

High Five StatesMississippi 1296 028 01(0105) 1796c

DC 1292 064 02(0131) 1759c

Louisiana 1275 023 03(0105) 1596c

Michigan 1214 014 04(0210) 1050Delaware 1201 045 05(0137) 927

Low Five StatesArizona 1014 016 47(3650) -774North Dakota 1013 049 48(1051) -788New Mexico 979 028 49(3651) -1093Utah 948 028 50(4351) -1372Colorado 922 018 51(4851) -1615c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1147 020 13(0533) 439 Montana 1052 040 40(0750) -428Alaska 1065 063 37(0351) -311 Nebraska 1107 032 29(0546) 071Arizona 1014 016 47(3650) -774 Nevada 1054 026 39(1649) -407Arkansas 1099 025 31(0745) 003 New Hampshire 1037 035 43(1350) -569California 1034 007 44(3748) -592 New Jersey 1131 015 16(0833) 292Colorado 922 018 51(4851) -1615c New Mexico 979 028 49(3651) -1093Connecticut 1069 022 36(1748) -272 New York 1111 010 26(1535) 110Delaware 1201 045 05(0137) 927 North Carolina 1102 014 30(1439) 024DC 1292 064 02(0131) 1759c North Dakota 1013 049 48(1051) -788Florida 1043 008 42(3547) -511 Ohio 1173 013 07(0419) 669Georgia 1064 015 38(2646) -315 Oklahoma 1099 022 32(0943) 003Hawaii 1098 035 33(0548) -007 Oregon 1156 022 11(0432) 520Idaho 1154 036 12(0340) 502 Pennsylvania 1196 012 06(0312) 878Illinois 1111 012 25(1236) 112 Rhode Island 1168 043 09(0141) 628Indiana 1159 018 10(0429) 546 South Carolina 1138 020 15(0536) 354Iowa 1119 024 22(0641) 177 South Dakota 1116 047 23(0349) 153Kansas 1120 026 21(0541) 192 Tennessee 1122 017 19(0837) 205Kentucky 1121 021 20(0639) 196 Texas 1023 009 45(3849) -697Louisiana 1275 023 03(0105) 1596c Utah 948 028 50(4351) -1372Maine 1111 034 27(0447) 109 Vermont 1075 052 34(0450) -222Maryland 1145 019 14(0533) 421 Virginia 1109 016 28(1139) 087Massachusetts 1129 017 17(0735) 273 Washington 1069 017 35(2046) -270Michigan 1214 014 04(0210) 1050 West Virginia 1044 029 41(1850) -504Minnesota 1113 019 24(0839) 125 Wisconsin 1170 018 08(0425) 650Mississippi 1296 028 01(0105) 1796c Wyoming 1016 056 46(0751) -757Missouri 1123 018 18(0837) 217

Table 2218Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 10 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1268 004

High Five StatesMississippi 1540 047 01(0107) 2148c

Louisiana 1482 037 02(0109) 1692c

DC 1482 107 03(0144) 1690c

Pennsylvania 1413 020 04(0212) 1147c

Delaware 1409 073 05(0140) 1114c

Low Five StatesMontana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c

New Mexico 1122 045 49(2951) -1150c

Utah 1080 044 50(3651) -1477c

Colorado 1073 030 51(4351) -1540c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1332 033 12(0435) 508 Montana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c Nebraska 1319 053 17(0244) 406Arizona 1160 025 46(3350) -850 Nevada 1173 040 42(2251) -751Arkansas 1268 040 28(0646) 006 New Hampshire 1205 056 39(0951) -498California 1179 012 41(3548) -699 New Jersey 1279 024 26(1038) 091Colorado 1073 030 51(4351) -1540c New Mexico 1122 045 49(2951) -1150c

Connecticut 1221 036 36(1448) -365 New York 1277 016 27(1436) 077Delaware 1409 073 05(0140) 1114c North Carolina 1296 023 23(0836) 222DC 1482 107 03(0144) 1690c North Dakota 1216 081 37(0351) -410Florida 1214 014 38(2944) -421 Ohio 1328 021 13(0630) 472Georgia 1233 024 32(1845) -273 Oklahoma 1261 036 29(0946) -051Hawaii 1239 056 31(0550) -229 Oregon 1334 035 11(0335) 520Idaho 1322 056 16(0245) 425 Pennsylvania 1413 020 04(0212) 1147c

Illinois 1309 021 19(0733) 322 Rhode Island 1394 071 06(0141) 995Indiana 1363 029 10(0327) 753 South Carolina 1323 033 14(0436) 435Iowa 1300 039 20(0441) 251 South Dakota 1223 073 35(0351) -355Kansas 1258 042 30(0747) -073 Tennessee 1290 028 24(0839) 172Kentucky 1296 034 22(0540) 222 Texas 1163 015 44(3649) -825Louisiana 1482 037 02(0109) 1692c Utah 1080 044 50(3651) -1477c

Maine 1194 054 40(0951) -581 Vermont 1231 083 33(0251) -288Maryland 1366 031 08(0328) 775 Virginia 1315 026 18(0634) 370Massachusetts 1298 027 21(0737) 237 Washington 1228 027 34(1846) -314Michigan 1387 023 07(0218) 943 West Virginia 1161 046 45(1951) -840Minnesota 1281 030 25(0841) 109 Wisconsin 1363 030 09(0329) 755Mississippi 1540 047 01(0107) 2148c Wyoming 1168 088 43(0351) -787Missouri 1323 029 15(0534) 434

Table 2219Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 957 003

High Five StatesDC 1144 079 01(0140) 1953c

Louisiana 1104 028 02(0111) 1536c

Mississippi 1104 034 03(0115) 1531c

Michigan 1067 018 04(0113) 1143Ohio 1041 016 05(0219) 879

Low Five StatesWyoming 864 071 47(0451) -974New Mexico 854 036 48(2451) -1076North Dakota 833 061 49(0951) -1297Utah 830 036 50(3451) -1331Colorado 792 023 51(4651) -1723c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 987 025 19(0440) 313 Montana 955 053 30(0250) -018Alaska 1014 084 09(0151) 596 Nebraska 927 040 41(0650) -320Arizona 881 020 45(3150) -800 Nevada 942 034 36(0649) -162Arkansas 949 031 33(0648) -090 New Hampshire 878 044 46(1151) -832California 912 009 42(3247) -474 New Jersey 1011 018 10(0429) 565Colorado 792 023 51(4651) -1723c New Mexico 854 036 48(2451) -1076Connecticut 945 027 35(0948) -131 New York 978 012 22(0935) 217Delaware 1035 056 07(0147) 808 North Carolina 945 017 34(1444) -124DC 1144 079 01(0140) 1953c North Dakota 833 061 49(0951) -1297Florida 895 011 44(3549) -648 Ohio 1041 016 05(0219) 879Georgia 927 018 40(1947) -316 Oklahoma 963 028 28(0646) 059Hawaii 978 045 23(0248) 217 Oregon 1008 028 11(0238) 535Idaho 998 046 14(0148) 424 Pennsylvania 1017 015 08(0426) 619Illinois 954 015 31(1442) -034 Rhode Island 993 052 16(0149) 376Indiana 992 022 18(0539) 360 South Carolina 985 025 20(0541) 290Iowa 964 030 27(0646) 071 South Dakota 998 060 13(0149) 424Kansas 998 033 15(0243) 422 Tennessee 981 021 21(0641) 243Kentucky 976 026 25(0543) 191 Texas 902 011 43(3348) -578Louisiana 1104 028 02(0111) 1536c Utah 830 036 50(3451) -1331Maine 1037 045 06(0142) 832 Vermont 949 065 32(0151) -088Maryland 976 023 24(0642) 194 Virginia 939 019 37(1446) -195Massachusetts 993 021 17(0538) 371 Washington 934 021 39(1447) -240Michigan 1067 018 04(0113) 1143 West Virginia 937 037 38(0650) -211Minnesota 967 024 26(0744) 107 Wisconsin 1002 023 12(0437) 464Mississippi 1104 034 03(0115) 1531c Wyoming 864 071 47(0451) -974Missouri 956 022 29(0945) -012

Table 2220Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control and PreventionRates are per 100000 and are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1130)

b The SEER 9 areas are San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah and AtlantaThe SEER 13 areas comprise the SEER 9 areas plus San Jose-Monterey Los Angeles the Alaska Native Registry and Rural GeorgiaThe SEER 18 areas comprise the SEER 13 areas plus California excluding SFSJMLA Kentucky Louisiana New Jersey and Georgiaexcluding ATLRGThe SEER 21 areas comprise the SEER 18 areas plus Idaho New York and Massachusetts

- Statistic not shown Rate based on less than 16 cases for the time interval

All Races Whites Blacks Total Males Females Total Males Females Total Males Females

SEER Death Ratesa 2013-2017

California 1034 1179 912 1070 1227 936 1257 1441 1115Greater Bay Area 983 1100 884 1037 1157 933 1316 1553 1137San Francisco-Oakland 991 1109 891 1037 1151 937 1325 1542 1156San Jose-Monterey 968 1084 869 1036 1167 923 1305 1678 -

Los Angeles 1045 1175 940 1071 1217 951 1291 1423 1197Greater California 1047 1208 909 1079 1251 930 1191 1396 1017

Connecticut 1069 1221 945 1075 1238 941 1155 1223 1094Detroit 1236 1373 1121 1202 1366 1059 1430 1498 1371Georgia 1064 1233 927 1033 1222 875 1217 1347 1117Atlanta 1034 1175 926 988 1142 867 1179 1346 1063Rural Georgia 988 1225 785 992 1269 745 1036 - -Greater Georgia 1086 1266 937 1055 1255 883 1264 1364 1179

Hawaii 1098 1239 978 1236 1304 1145 - - -Idaho 1154 1322 998 1170 1350 1001 - - -Iowa 1119 1300 964 1114 1298 958 1537 1577 1452Kentucky 1121 1296 976 1112 1290 964 1348 1471 1215Louisiana 1275 1482 1104 1208 1436 1022 1494 1660 1348Massachusetts 1129 1298 993 1157 1327 1020 1004 1272 801New Jersey 1131 1279 1011 1160 1316 1031 1253 1401 1147New Mexico 979 1122 854 996 1127 878 1275 1596 -New York 1111 1277 978 1149 1327 1002 1106 1266 991Seattle-Puget Sound 1047 1191 923 1064 1199 944 1335 1677 1065Utah 948 1080 830 950 1078 835 - - -

SEER 9 Areasb 1063 1205 944 1068 1213 942 1272 1410 1165SEER 13 Areasb 1054 1191 940 1068 1211 944 1274 1416 1168SEER 18 Areasb 1079 1231 951 1089 1251 951 1294 1441 1179SEER 21 Areasb 1089 1245 960 1106 1271 966 1235 1391 1115

Total US 1099 1268 957 1094 1270 943 1330 1491 1204

Table 2217Cancer of the Pancreas (Invasive)

Age-Adjusted SEER Death Ratesa

By Registry Race and Sex

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1099 002

High Five StatesMississippi 1296 028 01(0105) 1796c

DC 1292 064 02(0131) 1759c

Louisiana 1275 023 03(0105) 1596c

Michigan 1214 014 04(0210) 1050Delaware 1201 045 05(0137) 927

Low Five StatesArizona 1014 016 47(3650) -774North Dakota 1013 049 48(1051) -788New Mexico 979 028 49(3651) -1093Utah 948 028 50(4351) -1372Colorado 922 018 51(4851) -1615c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1147 020 13(0533) 439 Montana 1052 040 40(0750) -428Alaska 1065 063 37(0351) -311 Nebraska 1107 032 29(0546) 071Arizona 1014 016 47(3650) -774 Nevada 1054 026 39(1649) -407Arkansas 1099 025 31(0745) 003 New Hampshire 1037 035 43(1350) -569California 1034 007 44(3748) -592 New Jersey 1131 015 16(0833) 292Colorado 922 018 51(4851) -1615c New Mexico 979 028 49(3651) -1093Connecticut 1069 022 36(1748) -272 New York 1111 010 26(1535) 110Delaware 1201 045 05(0137) 927 North Carolina 1102 014 30(1439) 024DC 1292 064 02(0131) 1759c North Dakota 1013 049 48(1051) -788Florida 1043 008 42(3547) -511 Ohio 1173 013 07(0419) 669Georgia 1064 015 38(2646) -315 Oklahoma 1099 022 32(0943) 003Hawaii 1098 035 33(0548) -007 Oregon 1156 022 11(0432) 520Idaho 1154 036 12(0340) 502 Pennsylvania 1196 012 06(0312) 878Illinois 1111 012 25(1236) 112 Rhode Island 1168 043 09(0141) 628Indiana 1159 018 10(0429) 546 South Carolina 1138 020 15(0536) 354Iowa 1119 024 22(0641) 177 South Dakota 1116 047 23(0349) 153Kansas 1120 026 21(0541) 192 Tennessee 1122 017 19(0837) 205Kentucky 1121 021 20(0639) 196 Texas 1023 009 45(3849) -697Louisiana 1275 023 03(0105) 1596c Utah 948 028 50(4351) -1372Maine 1111 034 27(0447) 109 Vermont 1075 052 34(0450) -222Maryland 1145 019 14(0533) 421 Virginia 1109 016 28(1139) 087Massachusetts 1129 017 17(0735) 273 Washington 1069 017 35(2046) -270Michigan 1214 014 04(0210) 1050 West Virginia 1044 029 41(1850) -504Minnesota 1113 019 24(0839) 125 Wisconsin 1170 018 08(0425) 650Mississippi 1296 028 01(0105) 1796c Wyoming 1016 056 46(0751) -757Missouri 1123 018 18(0837) 217

Table 2218Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 10 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1268 004

High Five StatesMississippi 1540 047 01(0107) 2148c

Louisiana 1482 037 02(0109) 1692c

DC 1482 107 03(0144) 1690c

Pennsylvania 1413 020 04(0212) 1147c

Delaware 1409 073 05(0140) 1114c

Low Five StatesMontana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c

New Mexico 1122 045 49(2951) -1150c

Utah 1080 044 50(3651) -1477c

Colorado 1073 030 51(4351) -1540c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1332 033 12(0435) 508 Montana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c Nebraska 1319 053 17(0244) 406Arizona 1160 025 46(3350) -850 Nevada 1173 040 42(2251) -751Arkansas 1268 040 28(0646) 006 New Hampshire 1205 056 39(0951) -498California 1179 012 41(3548) -699 New Jersey 1279 024 26(1038) 091Colorado 1073 030 51(4351) -1540c New Mexico 1122 045 49(2951) -1150c

Connecticut 1221 036 36(1448) -365 New York 1277 016 27(1436) 077Delaware 1409 073 05(0140) 1114c North Carolina 1296 023 23(0836) 222DC 1482 107 03(0144) 1690c North Dakota 1216 081 37(0351) -410Florida 1214 014 38(2944) -421 Ohio 1328 021 13(0630) 472Georgia 1233 024 32(1845) -273 Oklahoma 1261 036 29(0946) -051Hawaii 1239 056 31(0550) -229 Oregon 1334 035 11(0335) 520Idaho 1322 056 16(0245) 425 Pennsylvania 1413 020 04(0212) 1147c

Illinois 1309 021 19(0733) 322 Rhode Island 1394 071 06(0141) 995Indiana 1363 029 10(0327) 753 South Carolina 1323 033 14(0436) 435Iowa 1300 039 20(0441) 251 South Dakota 1223 073 35(0351) -355Kansas 1258 042 30(0747) -073 Tennessee 1290 028 24(0839) 172Kentucky 1296 034 22(0540) 222 Texas 1163 015 44(3649) -825Louisiana 1482 037 02(0109) 1692c Utah 1080 044 50(3651) -1477c

Maine 1194 054 40(0951) -581 Vermont 1231 083 33(0251) -288Maryland 1366 031 08(0328) 775 Virginia 1315 026 18(0634) 370Massachusetts 1298 027 21(0737) 237 Washington 1228 027 34(1846) -314Michigan 1387 023 07(0218) 943 West Virginia 1161 046 45(1951) -840Minnesota 1281 030 25(0841) 109 Wisconsin 1363 030 09(0329) 755Mississippi 1540 047 01(0107) 2148c Wyoming 1168 088 43(0351) -787Missouri 1323 029 15(0534) 434

Table 2219Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 957 003

High Five StatesDC 1144 079 01(0140) 1953c

Louisiana 1104 028 02(0111) 1536c

Mississippi 1104 034 03(0115) 1531c

Michigan 1067 018 04(0113) 1143Ohio 1041 016 05(0219) 879

Low Five StatesWyoming 864 071 47(0451) -974New Mexico 854 036 48(2451) -1076North Dakota 833 061 49(0951) -1297Utah 830 036 50(3451) -1331Colorado 792 023 51(4651) -1723c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 987 025 19(0440) 313 Montana 955 053 30(0250) -018Alaska 1014 084 09(0151) 596 Nebraska 927 040 41(0650) -320Arizona 881 020 45(3150) -800 Nevada 942 034 36(0649) -162Arkansas 949 031 33(0648) -090 New Hampshire 878 044 46(1151) -832California 912 009 42(3247) -474 New Jersey 1011 018 10(0429) 565Colorado 792 023 51(4651) -1723c New Mexico 854 036 48(2451) -1076Connecticut 945 027 35(0948) -131 New York 978 012 22(0935) 217Delaware 1035 056 07(0147) 808 North Carolina 945 017 34(1444) -124DC 1144 079 01(0140) 1953c North Dakota 833 061 49(0951) -1297Florida 895 011 44(3549) -648 Ohio 1041 016 05(0219) 879Georgia 927 018 40(1947) -316 Oklahoma 963 028 28(0646) 059Hawaii 978 045 23(0248) 217 Oregon 1008 028 11(0238) 535Idaho 998 046 14(0148) 424 Pennsylvania 1017 015 08(0426) 619Illinois 954 015 31(1442) -034 Rhode Island 993 052 16(0149) 376Indiana 992 022 18(0539) 360 South Carolina 985 025 20(0541) 290Iowa 964 030 27(0646) 071 South Dakota 998 060 13(0149) 424Kansas 998 033 15(0243) 422 Tennessee 981 021 21(0641) 243Kentucky 976 026 25(0543) 191 Texas 902 011 43(3348) -578Louisiana 1104 028 02(0111) 1536c Utah 830 036 50(3451) -1331Maine 1037 045 06(0142) 832 Vermont 949 065 32(0151) -088Maryland 976 023 24(0642) 194 Virginia 939 019 37(1446) -195Massachusetts 993 021 17(0538) 371 Washington 934 021 39(1447) -240Michigan 1067 018 04(0113) 1143 West Virginia 937 037 38(0650) -211Minnesota 967 024 26(0744) 107 Wisconsin 1002 023 12(0437) 464Mississippi 1104 034 03(0115) 1531c Wyoming 864 071 47(0451) -974Missouri 956 022 29(0945) -012

Table 2220Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1099 002

High Five StatesMississippi 1296 028 01(0105) 1796c

DC 1292 064 02(0131) 1759c

Louisiana 1275 023 03(0105) 1596c

Michigan 1214 014 04(0210) 1050Delaware 1201 045 05(0137) 927

Low Five StatesArizona 1014 016 47(3650) -774North Dakota 1013 049 48(1051) -788New Mexico 979 028 49(3651) -1093Utah 948 028 50(4351) -1372Colorado 922 018 51(4851) -1615c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1147 020 13(0533) 439 Montana 1052 040 40(0750) -428Alaska 1065 063 37(0351) -311 Nebraska 1107 032 29(0546) 071Arizona 1014 016 47(3650) -774 Nevada 1054 026 39(1649) -407Arkansas 1099 025 31(0745) 003 New Hampshire 1037 035 43(1350) -569California 1034 007 44(3748) -592 New Jersey 1131 015 16(0833) 292Colorado 922 018 51(4851) -1615c New Mexico 979 028 49(3651) -1093Connecticut 1069 022 36(1748) -272 New York 1111 010 26(1535) 110Delaware 1201 045 05(0137) 927 North Carolina 1102 014 30(1439) 024DC 1292 064 02(0131) 1759c North Dakota 1013 049 48(1051) -788Florida 1043 008 42(3547) -511 Ohio 1173 013 07(0419) 669Georgia 1064 015 38(2646) -315 Oklahoma 1099 022 32(0943) 003Hawaii 1098 035 33(0548) -007 Oregon 1156 022 11(0432) 520Idaho 1154 036 12(0340) 502 Pennsylvania 1196 012 06(0312) 878Illinois 1111 012 25(1236) 112 Rhode Island 1168 043 09(0141) 628Indiana 1159 018 10(0429) 546 South Carolina 1138 020 15(0536) 354Iowa 1119 024 22(0641) 177 South Dakota 1116 047 23(0349) 153Kansas 1120 026 21(0541) 192 Tennessee 1122 017 19(0837) 205Kentucky 1121 021 20(0639) 196 Texas 1023 009 45(3849) -697Louisiana 1275 023 03(0105) 1596c Utah 948 028 50(4351) -1372Maine 1111 034 27(0447) 109 Vermont 1075 052 34(0450) -222Maryland 1145 019 14(0533) 421 Virginia 1109 016 28(1139) 087Massachusetts 1129 017 17(0735) 273 Washington 1069 017 35(2046) -270Michigan 1214 014 04(0210) 1050 West Virginia 1044 029 41(1850) -504Minnesota 1113 019 24(0839) 125 Wisconsin 1170 018 08(0425) 650Mississippi 1296 028 01(0105) 1796c Wyoming 1016 056 46(0751) -757Missouri 1123 018 18(0837) 217

Table 2218Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males and Females

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 10 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1268 004

High Five StatesMississippi 1540 047 01(0107) 2148c

Louisiana 1482 037 02(0109) 1692c

DC 1482 107 03(0144) 1690c

Pennsylvania 1413 020 04(0212) 1147c

Delaware 1409 073 05(0140) 1114c

Low Five StatesMontana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c

New Mexico 1122 045 49(2951) -1150c

Utah 1080 044 50(3651) -1477c

Colorado 1073 030 51(4351) -1540c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1332 033 12(0435) 508 Montana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c Nebraska 1319 053 17(0244) 406Arizona 1160 025 46(3350) -850 Nevada 1173 040 42(2251) -751Arkansas 1268 040 28(0646) 006 New Hampshire 1205 056 39(0951) -498California 1179 012 41(3548) -699 New Jersey 1279 024 26(1038) 091Colorado 1073 030 51(4351) -1540c New Mexico 1122 045 49(2951) -1150c

Connecticut 1221 036 36(1448) -365 New York 1277 016 27(1436) 077Delaware 1409 073 05(0140) 1114c North Carolina 1296 023 23(0836) 222DC 1482 107 03(0144) 1690c North Dakota 1216 081 37(0351) -410Florida 1214 014 38(2944) -421 Ohio 1328 021 13(0630) 472Georgia 1233 024 32(1845) -273 Oklahoma 1261 036 29(0946) -051Hawaii 1239 056 31(0550) -229 Oregon 1334 035 11(0335) 520Idaho 1322 056 16(0245) 425 Pennsylvania 1413 020 04(0212) 1147c

Illinois 1309 021 19(0733) 322 Rhode Island 1394 071 06(0141) 995Indiana 1363 029 10(0327) 753 South Carolina 1323 033 14(0436) 435Iowa 1300 039 20(0441) 251 South Dakota 1223 073 35(0351) -355Kansas 1258 042 30(0747) -073 Tennessee 1290 028 24(0839) 172Kentucky 1296 034 22(0540) 222 Texas 1163 015 44(3649) -825Louisiana 1482 037 02(0109) 1692c Utah 1080 044 50(3651) -1477c

Maine 1194 054 40(0951) -581 Vermont 1231 083 33(0251) -288Maryland 1366 031 08(0328) 775 Virginia 1315 026 18(0634) 370Massachusetts 1298 027 21(0737) 237 Washington 1228 027 34(1846) -314Michigan 1387 023 07(0218) 943 West Virginia 1161 046 45(1951) -840Minnesota 1281 030 25(0841) 109 Wisconsin 1363 030 09(0329) 755Mississippi 1540 047 01(0107) 2148c Wyoming 1168 088 43(0351) -787Missouri 1323 029 15(0534) 434

Table 2219Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 957 003

High Five StatesDC 1144 079 01(0140) 1953c

Louisiana 1104 028 02(0111) 1536c

Mississippi 1104 034 03(0115) 1531c

Michigan 1067 018 04(0113) 1143Ohio 1041 016 05(0219) 879

Low Five StatesWyoming 864 071 47(0451) -974New Mexico 854 036 48(2451) -1076North Dakota 833 061 49(0951) -1297Utah 830 036 50(3451) -1331Colorado 792 023 51(4651) -1723c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 987 025 19(0440) 313 Montana 955 053 30(0250) -018Alaska 1014 084 09(0151) 596 Nebraska 927 040 41(0650) -320Arizona 881 020 45(3150) -800 Nevada 942 034 36(0649) -162Arkansas 949 031 33(0648) -090 New Hampshire 878 044 46(1151) -832California 912 009 42(3247) -474 New Jersey 1011 018 10(0429) 565Colorado 792 023 51(4651) -1723c New Mexico 854 036 48(2451) -1076Connecticut 945 027 35(0948) -131 New York 978 012 22(0935) 217Delaware 1035 056 07(0147) 808 North Carolina 945 017 34(1444) -124DC 1144 079 01(0140) 1953c North Dakota 833 061 49(0951) -1297Florida 895 011 44(3549) -648 Ohio 1041 016 05(0219) 879Georgia 927 018 40(1947) -316 Oklahoma 963 028 28(0646) 059Hawaii 978 045 23(0248) 217 Oregon 1008 028 11(0238) 535Idaho 998 046 14(0148) 424 Pennsylvania 1017 015 08(0426) 619Illinois 954 015 31(1442) -034 Rhode Island 993 052 16(0149) 376Indiana 992 022 18(0539) 360 South Carolina 985 025 20(0541) 290Iowa 964 030 27(0646) 071 South Dakota 998 060 13(0149) 424Kansas 998 033 15(0243) 422 Tennessee 981 021 21(0641) 243Kentucky 976 026 25(0543) 191 Texas 902 011 43(3348) -578Louisiana 1104 028 02(0111) 1536c Utah 830 036 50(3451) -1331Maine 1037 045 06(0142) 832 Vermont 949 065 32(0151) -088Maryland 976 023 24(0642) 194 Virginia 939 019 37(1446) -195Massachusetts 993 021 17(0538) 371 Washington 934 021 39(1447) -240Michigan 1067 018 04(0113) 1143 West Virginia 937 037 38(0650) -211Minnesota 967 024 26(0744) 107 Wisconsin 1002 023 12(0437) 464Mississippi 1104 034 03(0115) 1531c Wyoming 864 071 47(0451) -974Missouri 956 022 29(0945) -012

Table 2220Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 10 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 1268 004

High Five StatesMississippi 1540 047 01(0107) 2148c

Louisiana 1482 037 02(0109) 1692c

DC 1482 107 03(0144) 1690c

Pennsylvania 1413 020 04(0212) 1147c

Delaware 1409 073 05(0140) 1114c

Low Five StatesMontana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c

New Mexico 1122 045 49(2951) -1150c

Utah 1080 044 50(3651) -1477c

Colorado 1073 030 51(4351) -1540c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 1332 033 12(0435) 508 Montana 1152 061 47(1151) -909Alaska 1123 096 48(0551) -1143c Nebraska 1319 053 17(0244) 406Arizona 1160 025 46(3350) -850 Nevada 1173 040 42(2251) -751Arkansas 1268 040 28(0646) 006 New Hampshire 1205 056 39(0951) -498California 1179 012 41(3548) -699 New Jersey 1279 024 26(1038) 091Colorado 1073 030 51(4351) -1540c New Mexico 1122 045 49(2951) -1150c

Connecticut 1221 036 36(1448) -365 New York 1277 016 27(1436) 077Delaware 1409 073 05(0140) 1114c North Carolina 1296 023 23(0836) 222DC 1482 107 03(0144) 1690c North Dakota 1216 081 37(0351) -410Florida 1214 014 38(2944) -421 Ohio 1328 021 13(0630) 472Georgia 1233 024 32(1845) -273 Oklahoma 1261 036 29(0946) -051Hawaii 1239 056 31(0550) -229 Oregon 1334 035 11(0335) 520Idaho 1322 056 16(0245) 425 Pennsylvania 1413 020 04(0212) 1147c

Illinois 1309 021 19(0733) 322 Rhode Island 1394 071 06(0141) 995Indiana 1363 029 10(0327) 753 South Carolina 1323 033 14(0436) 435Iowa 1300 039 20(0441) 251 South Dakota 1223 073 35(0351) -355Kansas 1258 042 30(0747) -073 Tennessee 1290 028 24(0839) 172Kentucky 1296 034 22(0540) 222 Texas 1163 015 44(3649) -825Louisiana 1482 037 02(0109) 1692c Utah 1080 044 50(3651) -1477c

Maine 1194 054 40(0951) -581 Vermont 1231 083 33(0251) -288Maryland 1366 031 08(0328) 775 Virginia 1315 026 18(0634) 370Massachusetts 1298 027 21(0737) 237 Washington 1228 027 34(1846) -314Michigan 1387 023 07(0218) 943 West Virginia 1161 046 45(1951) -840Minnesota 1281 030 25(0841) 109 Wisconsin 1363 030 09(0329) 755Mississippi 1540 047 01(0107) 2148c Wyoming 1168 088 43(0351) -787Missouri 1323 029 15(0534) 434

Table 2219Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Males

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 957 003

High Five StatesDC 1144 079 01(0140) 1953c

Louisiana 1104 028 02(0111) 1536c

Mississippi 1104 034 03(0115) 1531c

Michigan 1067 018 04(0113) 1143Ohio 1041 016 05(0219) 879

Low Five StatesWyoming 864 071 47(0451) -974New Mexico 854 036 48(2451) -1076North Dakota 833 061 49(0951) -1297Utah 830 036 50(3451) -1331Colorado 792 023 51(4651) -1723c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 987 025 19(0440) 313 Montana 955 053 30(0250) -018Alaska 1014 084 09(0151) 596 Nebraska 927 040 41(0650) -320Arizona 881 020 45(3150) -800 Nevada 942 034 36(0649) -162Arkansas 949 031 33(0648) -090 New Hampshire 878 044 46(1151) -832California 912 009 42(3247) -474 New Jersey 1011 018 10(0429) 565Colorado 792 023 51(4651) -1723c New Mexico 854 036 48(2451) -1076Connecticut 945 027 35(0948) -131 New York 978 012 22(0935) 217Delaware 1035 056 07(0147) 808 North Carolina 945 017 34(1444) -124DC 1144 079 01(0140) 1953c North Dakota 833 061 49(0951) -1297Florida 895 011 44(3549) -648 Ohio 1041 016 05(0219) 879Georgia 927 018 40(1947) -316 Oklahoma 963 028 28(0646) 059Hawaii 978 045 23(0248) 217 Oregon 1008 028 11(0238) 535Idaho 998 046 14(0148) 424 Pennsylvania 1017 015 08(0426) 619Illinois 954 015 31(1442) -034 Rhode Island 993 052 16(0149) 376Indiana 992 022 18(0539) 360 South Carolina 985 025 20(0541) 290Iowa 964 030 27(0646) 071 South Dakota 998 060 13(0149) 424Kansas 998 033 15(0243) 422 Tennessee 981 021 21(0641) 243Kentucky 976 026 25(0543) 191 Texas 902 011 43(3348) -578Louisiana 1104 028 02(0111) 1536c Utah 830 036 50(3451) -1331Maine 1037 045 06(0142) 832 Vermont 949 065 32(0151) -088Maryland 976 023 24(0642) 194 Virginia 939 019 37(1446) -195Massachusetts 993 021 17(0538) 371 Washington 934 021 39(1447) -240Michigan 1067 018 04(0113) 1143 West Virginia 937 037 38(0650) -211Minnesota 967 024 26(0744) 107 Wisconsin 1002 023 12(0437) 464Mississippi 1104 034 03(0115) 1531c Wyoming 864 071 47(0451) -974Missouri 956 022 29(0945) -012

Table 2220Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

a US Mortality Files National Center for Health Statistics Centers for Disease Control andPrevention Rates are per 100000 and are age-adjusted to the 2000 US Std Population (19age groups - Census P25-1130)

b Difference between state rate and total US rate is statistically significant (plt=0002)c Absolute percent difference between state rate and total US rate is 15 or mored Rank of state level death rate and the 95 confidence intervals (low high) for the rankSE Standard error of the ratePD Percent difference between state rate and total US rate- Statistic not shown Rate based on less than 16 cases for the time interval

State Rate SE Rank(CI)d PD TOTAL US 957 003

High Five StatesDC 1144 079 01(0140) 1953c

Louisiana 1104 028 02(0111) 1536c

Mississippi 1104 034 03(0115) 1531c

Michigan 1067 018 04(0113) 1143Ohio 1041 016 05(0219) 879

Low Five StatesWyoming 864 071 47(0451) -974New Mexico 854 036 48(2451) -1076North Dakota 833 061 49(0951) -1297Utah 830 036 50(3451) -1331Colorado 792 023 51(4651) -1723c

State Rate SE Rank(CI)d PD State Rate SE Rank(CI)d PD

Alabama 987 025 19(0440) 313 Montana 955 053 30(0250) -018Alaska 1014 084 09(0151) 596 Nebraska 927 040 41(0650) -320Arizona 881 020 45(3150) -800 Nevada 942 034 36(0649) -162Arkansas 949 031 33(0648) -090 New Hampshire 878 044 46(1151) -832California 912 009 42(3247) -474 New Jersey 1011 018 10(0429) 565Colorado 792 023 51(4651) -1723c New Mexico 854 036 48(2451) -1076Connecticut 945 027 35(0948) -131 New York 978 012 22(0935) 217Delaware 1035 056 07(0147) 808 North Carolina 945 017 34(1444) -124DC 1144 079 01(0140) 1953c North Dakota 833 061 49(0951) -1297Florida 895 011 44(3549) -648 Ohio 1041 016 05(0219) 879Georgia 927 018 40(1947) -316 Oklahoma 963 028 28(0646) 059Hawaii 978 045 23(0248) 217 Oregon 1008 028 11(0238) 535Idaho 998 046 14(0148) 424 Pennsylvania 1017 015 08(0426) 619Illinois 954 015 31(1442) -034 Rhode Island 993 052 16(0149) 376Indiana 992 022 18(0539) 360 South Carolina 985 025 20(0541) 290Iowa 964 030 27(0646) 071 South Dakota 998 060 13(0149) 424Kansas 998 033 15(0243) 422 Tennessee 981 021 21(0641) 243Kentucky 976 026 25(0543) 191 Texas 902 011 43(3348) -578Louisiana 1104 028 02(0111) 1536c Utah 830 036 50(3451) -1331Maine 1037 045 06(0142) 832 Vermont 949 065 32(0151) -088Maryland 976 023 24(0642) 194 Virginia 939 019 37(1446) -195Massachusetts 993 021 17(0538) 371 Washington 934 021 39(1447) -240Michigan 1067 018 04(0113) 1143 West Virginia 937 037 38(0650) -211Minnesota 967 024 26(0744) 107 Wisconsin 1002 023 12(0437) 464Mississippi 1104 034 03(0115) 1531c Wyoming 864 071 47(0451) -974Missouri 956 022 29(0945) -012

Table 2220Cancer of the Pancreas (Invasive)

Age-Adjusted Cancer Deatha Rates By State All Races 2013-2017

Females

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

a US 2017 cancer prevalence counts are based on 2017 cancer prevalence proportions from the SEER 13 Areas (excluding the AlaskaNative Registry) and 112017 US population estimates based on the average of 2016 and 2017 population estimates from theUS Bureau of the CensusPrevalence was calculated using the first invasive tumor for each cancer site diagnosed during the previous 25 years

b Maximum limited-duration prevalence is 25 years for 1992-2017 datac Percentages are age-adjusted to the 2000 US Standard Population (19 age groups - Census P25-1130) by 5-year age groupsd Cases diagnosed more than 25 years ago were estimated using the completeness index method (Capocaccia et al 1997

Merrill et al 2000)e Complete prevalence is obtained by summing lt=25 and gt 25- Statistic not shown Statistic based on fewer than 5 cases estimated alive in SEER for the time interval+ Not available

Years Since Diagnosis 0 to 5 gt 5 to 10 gt 10 to 15 gt 15 to 20 gt 20 to 25 lt=25b gt 25d Completee

Race Sex

All Races Both Sexes 57729 10952 4618 1929 1010 76239 2731 78969Males 29053 5759 1879 922 286 37899 1296 39194Females 28677 5193 2739 1007 724 38340 1435 39775

White Both Sexes 47797 8888 3811 1535 804 62836 2220 65055Males 24315 4813 1594 812 246 31779 1120 32898Females 23482 4075 2218 724 558 31057 1100 32157

Black Both Sexes 6894 1388 510 247 114 9153 861 10015Males 3194 619 177 70 9 4069 404 4473Females 3700 770 333 177 105 5085 457 5541

Asian Both Sexes 2378 526 211 85 52 3252 + +Pacific Males 1159 241 85 20 13 1518 + +Islander Females 1219 285 127 64 38 1734 + +

Hispanic Both Sexes 4702 805 408 181 108 6204 + +Males 2021 361 133 71 5 2591 + +Females 2681 445 274 110 103 3613 + +

Age Specific (Crude) Age-Adjustedc Age at Prevalence All Ages 0-9 10-19 20-29 30-39 40-49 50-59 60-69 70-79 80+ All Ages

Race Sex

All Races Both Sexes 00235 00000 00004 00011 00033 00103 00283 00650 01048 00977 00196Males 00237 00001 00003 00004 00026 00087 00291 00723 01202 01108 00211Females 00233 - 00005 00018 00040 00118 00275 00585 00919 00896 00184

White Both Sexes 00248 00000 00004 00012 00031 00097 00272 00643 01057 00980 00194Males 00253 00001 00003 00004 00026 00082 00281 00722 01202 01132 00210Females 00243 - 00004 00021 00037 00112 00263 00569 00933 00884 00181

Black Both Sexes 00201 - 00003 00006 00039 00130 00366 00770 01050 00895 00216Males 00186 - 00003 00005 00027 00098 00382 00814 01264 00690 00219Females 00215 - 00003 00007 00050 00159 00352 00735 00900 00997 00213

Asian Both Sexes 00156 00003 00009 00007 00039 00101 00224 00497 00814 00921 00164Pacific Males 00152 00005 00005 00004 00028 00112 00218 00488 00987 01006 00176Islander Females 00160 - 00014 00010 00048 00091 00230 00505 00675 00865 00156

Hispanic Both Sexes 00107 - 00004 00014 00030 00086 00211 00516 00801 00840 00158Males 00088 - 00005 00004 00014 00065 00181 00490 00875 00799 00149Females 00126 - 00004 00025 00047 00108 00241 00540 00744 00866 00167

Table 2221Cancer of the Pancreas (Invasive)

Estimated United States Cancer Prevalence Countsa on January 1 2017By RaceEthnicity Sex and Years Since Diagnosis

Estimated prevalence percenta on January 1 2017 of the SEER population diagnosed in the previous 25 yearsBy Age at Prevalence RaceEthnicity and Sex

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Source SEER 21 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New JerseyGeorgia excluding ATLRG Idaho New York and Massachusetts)Percents may not sum to 100 due to rounding

a Excludes Kaposi Sarcoma mesothelioma lymphomas leukemias myelomas lymphoreticular and immunoproliferative diseasesb Estimates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesc Hispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives

Underlying incidence data for Hispanics are based on NHIA and exclude cases from the Alaska Native Registryd Epidermoid carcinoma includes squamous basal and transitional cell carcinomase Adenocarcinoma includes histologies 80508140-81478160-81628180-82218250-850785148520-855185608570-857485768940-8941f Other adenocarcinoma include histologies 80508141-81478160-81628180-82218250-82598261-84798483-84998504-85068520-8551

85608570-857485768940-8941g Other specific carcinomas include histologies 8012-80158030-80468150-81558170-81808230-824985088510-85138561-85628575

8580-8671h Other carcinomas include histologies 8012-80158030-80468170-81808230-824985088510-85138561-856285758580-8671i Sarcoma and other soft tissue tumors include histologies 8680-87138800-89218990-89919040-90449120-91369150-92529370-9373

9540-9582j Other specific types include histologies 8720-87908930-89368950-90309060-91109260-93659380-9539- Statistic not shown due to fewer than 16 cases during the time period

AsianPacific American IndianAll Races White Black Islander Alaska Nativeb Hispanicc

Histologya Count Percent Count Percent Count Percent Count Percent Count Percent Count Percent

Carcinoma 72717 985 58010 985 9047 984 4974 983 251 977 7796 981Epidermoid carcinomad 198 03 149 03 28 03 16 03 - - 26 03(8051-8131)

Adenocarcinomae 62748 850 50250 853 7767 845 4188 828 211 821 6651 836Adenocarcinoma NOS 49487 670 39612 673 6284 683 3178 628 167 650 5135 646(8140)

Papillary adenocarcinoma 40 01 31 01 - - - - - - - -NOS (8260)

Mucinous adenocarcinoma 1550 21 1274 22 141 15 116 23 - - 177 22(84808482)

Mucin-producing 354 05 278 05 52 06 22 04 - - 34 04adenocarcinoma (8481)

Infiltrating duct carcinoma 9099 123 7283 124 1039 113 692 137 31 121 971 122(8500-850385078514)

Other adenocarcinomaf 2218 30 1772 30 247 27 175 35 - - 328 41Other specific carcinomasg 7494 101 5895 100 894 97 589 116 26 101 846 106Islet cell carcinoma 328 04 267 05 40 04 17 03 - - 21 03(8150-8155)

Other carcinomash 7166 97 5628 96 854 93 572 113 25 97 825 104Unspecified Carcinoma NOS 2278 31 1717 29 358 39 181 36 - - 274 34(80108020-8022)

Sarcoma and other soft tissue 62 01 50 01 - - - - - - - -tumorsi

Other specific typesj 75 01 57 01 - - - - - - - -

Unspecified (8000-8005) 984 13 767 13 130 14 74 15 - - 132 17

Total 73839 1000 58885 1000 9194 1000 5061 1000 257 1000 7951 1000

Table 2222

Cancer of the Pancreas (Invasive)

Percent Distribution and Counts by Histology among Histologically Confirmed Cases 2013-2017Both Sexes by Race

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

0

5

10

15

20

25

30

1975 1985 1995 2005 20170

5

10

15

20

25

30

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 20170

2

4

6

8

10

12

14

16

18

20

1975 1985 1995 2005 2017

Delay-Adj IncidenceDelay-Adj Incidence

Observed IncidenceObserved Incidence

MortalityMortality

SEER Observed Incidence SEER Delay Adjusted Incidence and US Death RatesCancer of the Pancreas by Race and Sex

a

Figure 221

Source SEER 9 areas and US Mortality Files (National Center for Health Statistics CDC)Rates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines and APCs are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer InstituteThe APC is the Annual Percent Change for the regression line segments The APC shown on the graph is for the most recent trendThe APC is significantly different from zero (p lt 005)

a

White Male Black Male White Female Black FemaleRate per 100000 Rate per 100000 Rate per 100000 Rate per 100000

Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath Year of DiagnosisDeath

SEER Incidence APCsDelay Adj 1994-17 = 09Observed 2007-17 = 04

US Mortality APC1997-17 = 04

SEER Incidence APCsDelay Adj 1975-17 = -04Observed 1975-17 = -04

US Mortality APC2001-17 = -03

SEER Incidence APCsDelay Adj 1996-17 = 11Observed 1996-17 = 10

US Mortality APC2006-17 = 01

SEER Incidence APCsDelay Adj 1975-17 = 01Observed 1975-17 = 01

US Mortality APC1986-17 = -03

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

Joinpoint Analyses for Whites and Blacks from 1975-2017and for AsianPacific Islanders American IndiansAlaska Natives and Hispanics from 2000-2017

0

5

10

15

20

1975 1985 1995 2005 20170

5

10

15

20

1975 1985 1995 2005 2017

White

Black

API

AIAN

Hispanic

SEER Incidence and US Death RatesCancer of the Pancreas Both Sexes

Figure 222

Source Incidence data for whites and blacks are from the SEER 9 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah Atlanta)Incidence data for AsianPacific Islanders American IndiansAlaska Natives and Hispanics are from the SEER 21 areas (SEER 9 areas San Jose-MontereyLos Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLA Kentucky Louisiana New Jersey Georgia excluding ATLRG Idaho New York andMassachusetts)Mortality data are from US Mortality Files National Center for Health Statistics CDCRates are age-adjusted to the 2000 US Std Population (19 age groups - Census P25-1103)Regression lines are calculated using the Joinpoint Regression Program Version 48 April 2020 National Cancer Institute Joinpoint analyses for Whites andBlacks during the 1975-2017 period allow a maximum of 5 joinpoints Analyses for other ethnic groups during the period 2000-2017 allow a maximum of 3 joinpointsAPI = AsianPacific IslanderAIAN = American IndianAlaska Native Rates for American IndianAlaska Native are based on the PurchasedReferred Care Delivery Area (PRCDA) countiesHispanic is not mutually exclusive from whites blacks AsianPacific Islanders and American IndiansAlaska Natives Incidence data for Hispanics are based onNHIA and exclude cases from the Alaska Native Registry

Incidence MortalityRate per 100000 Rate per 100000

Year of Diagnosis Year of Death

a

d

a

b

c

c

b

d

SEE

R C

ancer Statistics Review

1975-2017N

ational Cancer Institute

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival

Figure 223

Cancer of the Pancreas5-Year SEER Conditional Relative Survival and

95 Confidence Intervals

Source SEER 18 areas (San Francisco Connecticut Detroit Hawaii Iowa New Mexico Seattle Utah AtlantaSan Jose-Monterey Los Angeles Alaska Native Registry Rural Georgia California excluding SFSJMLAKentucky Louisiana New Jersey and Georgia excluding ATLRG)Percent surviving is not shown if based on less than 25 casesConfidence intervals are not shown if length of the confidence interval is greater than 5 times the standard error

0

20

40

60

80

100Percent Surviving Next 5 Years

Stage at Diagnosis

Probabilty of surviving the next 5 years given the cohort has already survived 0 1 or 3 years

2000-2015 by stage at diagnosis

Survival Time Since Diagnosis

Localized Regional Distant Unstaged

0 year (at diagnosis) 1 year 3 years

SEER Cancer Statistics Review 1975-2017 National Cancer Institute

• Trends in SEER Incidence and US Mortality Both Sexes
• Trends in SEER Incidence and US Mortality Males
• Trends in SEER Incidence and US Mortality Females
• Annual Delay-adjusted Incidence Rates
• Annual Incidence Rates
• Annual Death Rates
• Incidence and Mortality Rates by Age
• 5-year Relative and Period Survival
• Relative Survival by Year of Diagnosis Both Sexes
• Relative Survival by Year of Diagnosis Males
• Relative Survival by Year of Diagnosis Females
• Risk of DevelopingDying Both Sexes
• Risk of DevelopingDying Males
• Risk of DevelopingDying Females
• Rates and Trends by RaceEthnicity
• Age-Adjusted SEER Incidence Rates by Registry
• Age-Adjusted SEER Death Rates by Registry
• Age-Adjusted Cancer Death Rates By State Both Sexes
• Age-Adjusted Cancer Death Rates By State Males
• Age-Adjusted Cancer Death Rates By State Females
• US Prevalence Estimates
• Case Distribution by Histology
• Graph - SEER Incidence Delay Adjusted Incidence and US Death Rates by Race and Sex
• Graph - SEER Incidence and US Death Rates by RaceEthnicity
• Graph - 5-Year SEER Conditional Relative Survival